Prevention of growth and metastasis of murine melanoma through enhanced natural-killer cytotoxicity by fatty acid-conjugate of protopanaxatriol

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 7, 2002, Pages 861-866

  Hasegawa, Hideo ^a   Suzuki, Ryuichi ^a   Nagaoka, Takema ^b   Tezuka, Yasuhiro ^b   Kadota, Shigetoshi ^b   Saiki, Ikuo ^b  

^a Happy World Inc   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

20(S) protopanaxatriol (M4); Esterification; Fatty acid; Ginsenoside; Immunostimulation; NK cell

Indexed keywords

2 CHLOROADENOSINE; FATTY ACID; GANGLIOTETRAOSYLCERAMIDE; GINSENOSIDE; PROTOPANAXATRIOL; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; SAPOGENIN; TRITERPENE;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG METABOLISM; ESTERIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; LUNG; LUNG METASTASIS; MASS SPECTROMETRY; MELANOMA; MESENTERY LYMPH NODE; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; SMALL INTESTINE ABSORPTION; SPLEEN CELL; THIN LAYER CHROMATOGRAPHY; TUMOR GROWTH; ANIMAL; BIOAVAILABILITY; C57BL MOUSE; CANCER TRANSPLANTATION; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; EXPERIMENTAL MELANOMA; FEMALE; GINSENG; IMMUNOLOGY; INTESTINE ABSORPTION; LUNG TUMOR; MALE; METABOLISM; METASTASIS; MICROBIOLOGY; ORAL DRUG ADMINISTRATION; SMALL INTESTINE;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOLOGICAL AVAILABILITY; CELL SURVIVAL; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; INTESTINAL ABSORPTION; INTESTINE, SMALL; KILLER CELLS, NATURAL; LUNG NEOPLASMS; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; PANAX; SAPOGENINS; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 0036633130     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.861     Document Type: Article

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