Reaction of cis -3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: Hydration via an enamine

Journal of the American Chemical Society

Volumn 134, Issue 1, 2012, Pages 293-304

  Schroeder, Gottfried K ^a   Johnson, William H ^a   Huddleston, Jamison P ^a   Serrano, Hector ^a   Johnson, Kenneth A ^b   Whitman, Christian P ^a,b  

^a The Center for Molecular Carcinogenesis and Toxicology   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COVALENT MODIFICATIONS; DEHALOGENASE; ENAMINES; ENZYME INACTIVATION; KINETIC EXPERIMENT; MALONATES; PRE-STEADY STATE; STEREOCHEMICAL ANALYSIS; TAUTOMERASE;

CATALYSIS; ENZYMES; HYDRATION; NITROGEN COMPOUNDS;

SUBSTRATES;

2,3 BUTADIENOATE; ACETOACETIC ACID; ACRYLIC ACID DERIVATIVE; ALLENE DERIVATIVE; CIS 3 CHLOROACRYLIC ACID DEHALOGENASE; ENAMINE; ENZYME; IMINE; MALONATE SEMIALDEHYDE DEHYDROGENASE (ACETYLATING); UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; COVALENT BOND; DEHALOGENATION; ENZYME INACTIVATION; HYDRATION; HYDROLYSIS; STEREOCHEMISTRY; TAUTOMER;

ALKADIENES; BIOCATALYSIS; BIPHENYL COMPOUNDS; BUTYRIC ACIDS; ENZYME INHIBITORS; HYDROLASES; IMIDAZOLES; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDE MAPPING; PROTEIN STRUCTURE, SECONDARY; PSEUDOMONAS; STAPHYLOCOCCUS AUREUS; STEREOISOMERISM;

EID: 84855697030     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja206873f     Document Type: Article

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