Pharmacophore analysis of the nuclear oxysterol receptor LXRα

Journal of Medicinal Chemistry

Volumn 44, Issue 6, 2001, Pages 886-897

  Spencer, T A ^a   Li, D ^a   Russel, J S ^a   Collins, J L ^b   Bledsoe, R K ^b   Consler, T G ^b   Moore, L B ^b   Galardi, C M ^b   McKee, D D ^b   Moore, J T ^b   Watson, M A ^b   Parks, D J ^b   Lambert, M H ^b   Willson, T M ^b  

^a Dartmouth College ^*  (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

22 HYDROXYCHOLESTEROL; 24,25 EPOXYCHOLESTEROL; CELL NUCLEUS RECEPTOR; CHOLENIC ACID DIMETHYLAMIDE; CHOLESTEROL DERIVATIVE; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG;

ARTICLE; CELL FREE SYSTEM; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; LIGAND BINDING; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; CELL-FREE SYSTEM; CERCOPITHECUS AETHIOPS; CHOLESTEROL; CHOLIC ACIDS; DNA-BINDING PROTEINS; ENERGY TRANSFER; FLUORESCENCE; HISTONE ACETYLTRANSFERASES; HYDROXYCHOLESTEROLS; KETOCHOLESTEROLS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; STEREOISOMERISM; STEROLS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TRYPTOPHAN;

EID: 0035866585     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0004749     Document Type: Article

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