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Volumn 13, Issue 4, 2010, Pages 343-349

Curcumin interrupts the interaction between the androgen receptor and Wnt/β-catenin signaling pathway in LNCaP prostate cancer cells

Author keywords

catenin; androgen receptor; curcumin

Indexed keywords

ANDROGEN RECEPTOR; BETA CATENIN; CURCUMIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; MYC PROTEIN; PROTEIN KINASE B; T CELL FACTOR PROTEIN; WNT PROTEIN;

EID: 78649322736     PISSN: 13657852     EISSN: 14765608     Source Type: Journal    
DOI: 10.1038/pcan.2010.26     Document Type: Article
Times cited : (91)

References (29)
  • 2
    • 0032483683 scopus 로고    scopus 로고
    • Nutritional and socioeconomic factors in relation to prostate cancer mortality: A cross-national study
    • Hebert JR, Hurley TG, Olendzki BC, Teas J, Ma Y, Hampl JS. Nutritional and socioeconomic factors in relation to prostate cancer mortality: a cross-national study. J Natl Cancer Inst 1998; 90: 1637-1647.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1637-1647
    • Hebert, J.R.1    Hurley, T.G.2    Olendzki, B.C.3    Teas, J.4    Ma, Y.5    Hampl, J.S.6
  • 3
    • 1842531175 scopus 로고    scopus 로고
    • Androgen receptor coregulators in prostate cancer: Mechanisms and clinical implications
    • Rahman M, Miyamoto H, Chang C. Androgen receptor coregulators in prostate cancer: mechanisms and clinical implications. Clin Cancer Res 2004; 10: 2208-2219.
    • (2004) Clin Cancer Res , vol.10 , pp. 2208-2219
    • Rahman, M.1    Miyamoto, H.2    Chang, C.3
  • 4
    • 33646533771 scopus 로고    scopus 로고
    • Roles and regulation of Wnt signaling and beta-catenin in prostate cancer
    • Verras M, Sun Z. Roles and regulation of Wnt signaling and beta-catenin in prostate cancer. Cancer Lett 2006; 237: 22-32.
    • (2006) Cancer Lett , vol.237 , pp. 22-32
    • Verras, M.1    Sun, Z.2
  • 5
    • 0034283030 scopus 로고    scopus 로고
    • Beta-catenin affects androgen receptor transcriptional activity and ligand specificity
    • Truica CI, Byers S, Gelmann EP. Beta-catenin affects androgen receptor transcriptional activity and ligand specificity. Cancer Res 2000; 60: 4709-4713.
    • (2000) Cancer Res , vol.60 , pp. 4709-4713
    • Truica, C.I.1    Byers, S.2    Gelmann, E.P.3
  • 7
    • 0037124062 scopus 로고    scopus 로고
    • The androgen receptor can promote beta-catenin nuclear transloca-tion independently of adenomatous polyposis coli
    • Mulholland DJ, Cheng H, Reid K, Rennie PS, Nelson CC. The androgen receptor can promote beta-catenin nuclear transloca-tion independently of adenomatous polyposis coli. J Biol Chem 2002; 277: 17933-17943.
    • (2002) J Biol Chem , vol.277 , pp. 17933-17943
    • Mulholland, D.J.1    Cheng, H.2    Reid, K.3    Rennie, P.S.4    Nelson, C.C.5
  • 8
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006; 127: 469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 9
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009; 17: 9-26.
    • (2009) Dev Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 10
    • 0347087570 scopus 로고    scopus 로고
    • Beta-catenin signaling in prostate cancer: An early perspective
    • Chesire DR, Isaacs WB. Beta-catenin signaling in prostate cancer: an early perspective. Endocr Relat Cancer 2003; 10: 537-560.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 537-560
    • Chesire, D.R.1    Isaacs, W.B.2
  • 11
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multitasking kinase
    • Doble BW, Woodgett JR. GSK-3: tricks of the trade for a multitasking kinase. J Cell Sci 2003; 116: 1175-1186.
    • (2003) J Cell Sci , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 12
    • 0037163032 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation
    • Sharma M, Chuang WW, Sun Z. Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation. J Biol Chem 2002; 277: 30935-30941.
    • (2002) J Biol Chem , vol.277 , pp. 30935-30941
    • Sharma, M.1    Chuang, W.W.2    Sun, Z.3
  • 13
    • 10144237223 scopus 로고    scopus 로고
    • Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells
    • Ohigashi T, Mizuno R, Nakashima J, Marumo K, Murai M. Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells. Prostate 2005; 62: 61-68.
    • (2005) Prostate , vol.62 , pp. 61-68
    • Ohigashi, T.1    Mizuno, R.2    Nakashima, J.3    Marumo, K.4    Murai, M.5
  • 14
    • 30944461586 scopus 로고    scopus 로고
    • PTEN and GSK3beta: Key regulators of progression to androgen-indepen-dent prostate cancer
    • Mulholland DJ, Dedhar S, Wu H, Nelson CC. PTEN and GSK3beta: key regulators of progression to androgen-indepen-dent prostate cancer. Oncogene 2006; 25: 329-337.
    • (2006) Oncogene , vol.25 , pp. 329-337
    • Mulholland, D.J.1    Dedhar, S.2    Wu, H.3    Nelson, C.C.4
  • 16
    • 0037129305 scopus 로고    scopus 로고
    • In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis
    • Chesire DR, Ewing CM, Gage WR, Isaacs WB. In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis. Oncogene 2002; 21: 2679-2694.
    • (2002) Oncogene , vol.21 , pp. 2679-2694
    • Chesire, D.R.1    Ewing, C.M.2    Gage, W.R.3    Isaacs, W.B.4
  • 18
    • 4444326415 scopus 로고    scopus 로고
    • Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications
    • Chen G, Shukeir N, Potti A, Sircar K, Aprikian A, Goltzman D et al. Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications. Cancer 2004; 101: 1345-1356.
    • (2004) Cancer , vol.101 , pp. 1345-1356
    • Chen, G.1    Shukeir, N.2    Potti, A.3    Sircar, K.4    Aprikian, A.5    Goltzman, D.6
  • 20
    • 58149143164 scopus 로고    scopus 로고
    • Prostate cancer and curcumin: Add spice to your life
    • Aggarwal BB. Prostate cancer and curcumin: add spice to your life. Cancer Biol Ther 2008; 7: 1436-1440.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1436-1440
    • Aggarwal, B.B.1
  • 21
    • 0033843216 scopus 로고    scopus 로고
    • Therapeutic potential of curcumin in human prostate cancer-I Curcumin induces apoptosis in both androgen-dependent and androgen-independent prostate cancer cells
    • Dorai T, Gehani N, Katz A. Therapeutic potential of curcumin in human prostate cancer-I. Curcumin induces apoptosis in both androgen-dependent and androgen-independent prostate cancer cells. Prostate Cancer Prostatic Dis 2000; 3: 84-93.
    • (2000) Prostate Cancer Prostatic Dis , vol.3 , pp. 84-93
    • Dorai, T.1    Gehani, N.2    Katz, A.3
  • 22
    • 0036781479 scopus 로고    scopus 로고
    • Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines
    • Nakamura K, Yasunaga Y, Segawa T, Ko D, Moul JW, Srivastava S et al. Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines. Int J Oncol 2002; 21: 825-830.
    • (2002) Int J Oncol , vol.21 , pp. 825-830
    • Nakamura, K.1    Yasunaga, Y.2    Segawa, T.3    Ko, D.4    Moul, J.W.5    Srivastava, S.6
  • 23
    • 56249138279 scopus 로고    scopus 로고
    • Curcumin blocks the activation of androgen and interlukin-6 on prostate-specific antigen expression in human prostatic carcinoma cells
    • Tsui KH, Feng TH, Lin CM, Chang PL, Juang HH. Curcumin blocks the activation of androgen and interlukin-6 on prostate-specific antigen expression in human prostatic carcinoma cells. J Androl 2008; 29: 661-668.
    • (2008) J Androl , vol.29 , pp. 661-668
    • Tsui, K.H.1    Feng, T.H.2    Lin, C.M.3    Chang, P.L.4    Juang, H.H.5
  • 24
    • 73449113640 scopus 로고    scopus 로고
    • Novel anti-prostate cancer curcumin analogues that enhance androgen receptor degradation activity
    • Shi Q, Shih CC, Lee KH. Novel anti-prostate cancer curcumin analogues that enhance androgen receptor degradation activity. Anticancer Agents Med Chem 2009; 9: 904-912.
    • (2009) Anticancer Agents Med Chem , vol.9 , pp. 904-912
    • Shi, Q.1    Shih, C.C.2    Lee, K.H.3
  • 25
    • 0033564514 scopus 로고    scopus 로고
    • The phospha-tidylinositol 3-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells
    • Lin J, Adam RM, Santiestevan E, Freeman MR. The phospha-tidylinositol 3-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells. Cancer Res 1999; 59: 2891-2897.
    • (1999) Cancer Res , vol.59 , pp. 2891-2897
    • Lin, J.1    Adam, R.M.2    Santiestevan, E.3    Freeman, M.R.4
  • 26
    • 30044446136 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation
    • Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol Pharmacol 2006; 69: 195-206.
    • (2006) Mol Pharmacol , vol.69 , pp. 195-206
    • Aggarwal, S.1    Ichikawa, H.2    Takada, Y.3    Sandur, S.K.4    Shishodia, S.5    Aggarwal, B.B.6
  • 27
    • 34247850953 scopus 로고    scopus 로고
    • Involvement of Bcl-2 family members, phosphatidylinositol 3-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer
    • Shankar S, Srivastava RK. Involvement of Bcl-2 family members, phosphatidylinositol 3-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer. Int J Oncol 2007; 30: 905-918.
    • (2007) Int J Oncol , vol.30 , pp. 905-918
    • Shankar, S.1    Srivastava, R.K.2
  • 28
    • 54049128202 scopus 로고    scopus 로고
    • Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism
    • Yu S, Shen G, Khor TO, Kim JH, Kong AN. Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism. Mol Cancer Ther 2008; 7: 2609-2620.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2609-2620
    • Yu, S.1    Shen, G.2    Khor, T.O.3    Kim, J.H.4    Kong, A.N.5
  • 29
    • 23044506681 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway and its role in cancer
    • Mani A, Gelmann EP. The ubiquitin-proteasome pathway and its role in cancer. J Clin Oncol 2005; 23: 4776-4789.
    • (2005) J Clin Oncol , vol.23 , pp. 4776-4789
    • Mani, A.1    Gelmann, E.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.