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Volumn 42, Issue 2, 2012, Pages 171-178

Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish population

Author keywords

Abdominal obesity; Genetic polymorphisms; Obesity; Uncoupling proteins

Indexed keywords

UNCOUPLING PROTEIN 2;

EID: 84855480203     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2011.02570.x     Document Type: Article
Times cited : (26)

References (36)
  • 2
    • 58149163142 scopus 로고    scopus 로고
    • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
    • Genetic Investigation of Anthropometric Traits Consortium.
    • Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM et al. Genetic Investigation of Anthropometric Traits Consortium. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009;41:25-34.
    • (2009) Nat Genet , vol.41 , pp. 25-34
    • Willer, C.J.1    Speliotes, E.K.2    Loos, R.J.3    Li, S.4    Lindgren, C.M.5    Heid, I.M.6
  • 3
    • 33947327738 scopus 로고    scopus 로고
    • Mitochondrial function and endocrine diseases
    • Stark R, Roden M. Mitochondrial function and endocrine diseases. Eur J Clin Invest 2007;37:236-48.
    • (2007) Eur J Clin Invest , vol.37 , pp. 236-248
    • Stark, R.1    Roden, M.2
  • 4
    • 84455207168 scopus 로고    scopus 로고
    • Genetic variance in uncoupling protein 2 in relation to obesity. Type 2 diabetes, and related metabolic traits: focus on the functional -866G>A promoter variant (rs659366)
    • Dalgaard LT. Genetic variance in uncoupling protein 2 in relation to obesity. Type 2 diabetes, and related metabolic traits: focus on the functional -866G>A promoter variant (rs659366). J Obes 2011;2011:340241.
    • (2011) J Obes , vol.2011 , pp. 340241
    • Dalgaard, L.T.1
  • 5
    • 0034883804 scopus 로고    scopus 로고
    • Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and type II diabetes
    • Dalgaard LT, Pedersen O. Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and type II diabetes. Diabetologia 2001;44:946-65.
    • (2001) Diabetologia , vol.44 , pp. 946-965
    • Dalgaard, L.T.1    Pedersen, O.2
  • 6
    • 68849099874 scopus 로고    scopus 로고
    • Could mitochondrial efficiency explain the susceptibility to adiposity, metabolic syndrome, diabetes and cardiovascular diseases in South Asian populations?
    • Bhopal RS, Rafnsson SB. Could mitochondrial efficiency explain the susceptibility to adiposity, metabolic syndrome, diabetes and cardiovascular diseases in South Asian populations? Int J Epidemiol 2009;38:1072-81.
    • (2009) Int J Epidemiol , vol.38 , pp. 1072-1081
    • Bhopal, R.S.1    Rafnsson, S.B.2
  • 7
    • 0031912624 scopus 로고    scopus 로고
    • Organization of the coding exons and mutational screening of the uncoupling protein 3 gene in subjects with juvenile-onset obesity
    • Urhammer SA, Dalgaard LT, Sorensen TI, Tybjaerg-Hansen A, Echwald SM, Andersen T et al. Organization of the coding exons and mutational screening of the uncoupling protein 3 gene in subjects with juvenile-onset obesity. Diabetologia 1998;41:241-4.
    • (1998) Diabetologia , vol.41 , pp. 241-244
    • Urhammer, S.A.1    Dalgaard, L.T.2    Sorensen, T.I.3    Tybjaerg-Hansen, A.4    Echwald, S.M.5    Andersen, T.6
  • 8
    • 1242284366 scopus 로고    scopus 로고
    • Uncoupling proteins: gender dependence and their relation to body weight control
    • Rodriguez AM, Palou A. Uncoupling proteins: gender dependence and their relation to body weight control. Int J Obes Relat Metab Disord 2004;28:500-2.
    • (2004) Int J Obes Relat Metab Disord , vol.28 , pp. 500-502
    • Rodriguez, A.M.1    Palou, A.2
  • 9
    • 69449089547 scopus 로고    scopus 로고
    • The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes
    • Jia JJ, Zhang X, Ge CR, Jois M. The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes. Obes Rev 2009;10:519-26.
    • (2009) Obes Rev , vol.10 , pp. 519-526
    • Jia, J.J.1    Zhang, X.2    Ge, C.R.3    Jois, M.4
  • 10
    • 38149097915 scopus 로고    scopus 로고
    • Renin polymorphisms and haplotypes are associated with blood pressure levels and hypertension risk in postmenopausal women
    • Mansego ML, Redon J, Marin R, Gonzalez-Albert V, Martin-Escudero JC, Fabia MJ et al. Renin polymorphisms and haplotypes are associated with blood pressure levels and hypertension risk in postmenopausal women. J Hypertens 2008;26:230-7.
    • (2008) J Hypertens , vol.26 , pp. 230-237
    • Mansego, M.L.1    Redon, J.2    Marin, R.3    Gonzalez-Albert, V.4    Martin-Escudero, J.C.5    Fabia, M.J.6
  • 17
    • 0021448003 scopus 로고
    • Influence of free glycerol on enzymatic of triglycerides
    • Ter HF, Baarscheer T, Fiolet JWT. Influence of free glycerol on enzymatic of triglycerides. Clin Chem 1984;30:1102-3.
    • (1984) Clin Chem , vol.30 , pp. 1102-1103
    • Ter, H.F.1    Baarscheer, T.2    Fiolet, J.W.T.3
  • 18
    • 0003072603 scopus 로고
    • Enzymatic colorimetric method for glucose determination
    • Trinder P. Enzymatic colorimetric method for glucose determination. Ann Clin Biochem 1969;6:24-7.
    • (1969) Ann Clin Biochem , vol.6 , pp. 24-27
    • Trinder, P.1
  • 19
    • 33747827929 scopus 로고    scopus 로고
    • SNPStats: a web tool for the analysis of association studies
    • Sole X, Guino E, Valls J, Iniesta R, Moreno V. SNPStats: a web tool for the analysis of association studies. Bioinformatics 2006;22:1928-9.
    • (2006) Bioinformatics , vol.22 , pp. 1928-1929
    • Sole, X.1    Guino, E.2    Valls, J.3    Iniesta, R.4    Moreno, V.5
  • 20
    • 67449141659 scopus 로고    scopus 로고
    • Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study
    • Goossens GH, Petersen L, Blaak EE, Hul G, Arner P, Astrup A et al. Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study. Int J Obes 2009;33:669-79.
    • (2009) Int J Obes , vol.33 , pp. 669-679
    • Goossens, G.H.1    Petersen, L.2    Blaak, E.E.3    Hul, G.4    Arner, P.5    Astrup, A.6
  • 21
    • 36148973232 scopus 로고    scopus 로고
    • Association between obesity and insulin resistance with UCP2-UCP3 gene variants in Spanish children and adolescents
    • GENOI Members.
    • Ochoa MC, Santos JL, Azcona C, Moreno-Aliaga MJ, Martinez-Gonzalez MA, Martinez JA et al. GENOI Members. Association between obesity and insulin resistance with UCP2-UCP3 gene variants in Spanish children and adolescents. Mol Genet Metab 2007;92:351-8.
    • (2007) Mol Genet Metab , vol.92 , pp. 351-358
    • Ochoa, M.C.1    Santos, J.L.2    Azcona, C.3    Moreno-Aliaga, M.J.4    Martinez-Gonzalez, M.A.5    Martinez, J.A.6
  • 22
    • 0034972150 scopus 로고    scopus 로고
    • A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans
    • Esterbauer H, Schneitler C, Oberkofler H, Ebenbichler C, Paulweber B, Sandhofer F et al. A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans. Nat Genet 2001;28:178-83.
    • (2001) Nat Genet , vol.28 , pp. 178-183
    • Esterbauer, H.1    Schneitler, C.2    Oberkofler, H.3    Ebenbichler, C.4    Paulweber, B.5    Sandhofer, F.6
  • 23
    • 70349563773 scopus 로고    scopus 로고
    • Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish diabetes prevention study
    • Salopuro T, Pulkkinen L, Lindström J, Kolehmainen M, Tolppanen AM, Eriksson JG et al. Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish diabetes prevention study. BMC Med Genet 2009;10:94.
    • (2009) BMC Med Genet , vol.10 , pp. 94
    • Salopuro, T.1    Pulkkinen, L.2    Lindström, J.3    Kolehmainen, M.4    Tolppanen, A.M.5    Eriksson, J.G.6
  • 24
    • 33846253751 scopus 로고    scopus 로고
    • Uncoupling protein 2 promoter polymorphism -866G/A, central adiposity, and metabolic syndrome in Asians
    • Shen H, Qi L, Tai ES, Chew SK, Tan CE, Ordovas JM. Uncoupling protein 2 promoter polymorphism -866G/A, central adiposity, and metabolic syndrome in Asians. Obesity 2006;14:656-61.
    • (2006) Obesity , vol.14 , pp. 656-661
    • Shen, H.1    Qi, L.2    Tai, E.S.3    Chew, S.K.4    Tan, C.E.5    Ordovas, J.M.6
  • 26
    • 77949653045 scopus 로고    scopus 로고
    • A common polymorphism in the promoter of UCP2 is associated with obesity and hyperinsulenemia in northern Indians
    • Srivastava N, Prakash J, Lakhan R, Agarwal CG, Pant DC, Mittal B. A common polymorphism in the promoter of UCP2 is associated with obesity and hyperinsulenemia in northern Indians. Mol Cell Biochem 2010;337:293-8.
    • (2010) Mol Cell Biochem , vol.337 , pp. 293-298
    • Srivastava, N.1    Prakash, J.2    Lakhan, R.3    Agarwal, C.G.4    Pant, D.C.5    Mittal, B.6
  • 27
    • 35648954193 scopus 로고    scopus 로고
    • UCP2 A55V variant is associated with obesity and related phenotypes in an aboriginal community in Taiwan
    • Wang TN, Huang MC, Lin HL, Hsiang CH, Ko AM, Chang WT et al. UCP2 A55V variant is associated with obesity and related phenotypes in an aboriginal community in Taiwan. Int J Obes 2007;31:1746-52.
    • (2007) Int J Obes , vol.31 , pp. 1746-1752
    • Wang, T.N.1    Huang, M.C.2    Lin, H.L.3    Hsiang, C.H.4    Ko, A.M.5    Chang, W.T.6
  • 28
    • 34248385690 scopus 로고    scopus 로고
    • Association of UCP2 and UCP3 gene polymorphisms with serum high-density lipoprotein cholesterol among Korean women
    • Cha MH, Kim IC, Kim KS, Kang BK, Choi SM, Yoon Y. Association of UCP2 and UCP3 gene polymorphisms with serum high-density lipoprotein cholesterol among Korean women. Metabolism 2007;56:806-13.
    • (2007) Metabolism , vol.56 , pp. 806-813
    • Cha, M.H.1    Kim, I.C.2    Kim, K.S.3    Kang, B.K.4    Choi, S.M.5    Yoon, Y.6
  • 29
    • 54249088345 scopus 로고    scopus 로고
    • Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM
    • Lee HJ, Ryu HJ, Shin HD, Park BL, Kim JY, Cho YM et al. Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM. Clin Chim Acta 2008;398:27-33.
    • (2008) Clin Chim Acta , vol.398 , pp. 27-33
    • Lee, H.J.1    Ryu, H.J.2    Shin, H.D.3    Park, B.L.4    Kim, J.Y.5    Cho, Y.M.6
  • 30
    • 0042160141 scopus 로고    scopus 로고
    • The role of uncoupling proteins in the regulation of metabolism
    • Erlanson-Albertsson C. The role of uncoupling proteins in the regulation of metabolism. Acta Physiol Scand 2003;78:405-12.
    • (2003) Acta Physiol Scand , vol.78 , pp. 405-412
    • Erlanson-Albertsson, C.1
  • 31
    • 34250354410 scopus 로고    scopus 로고
    • Effects of genetic polymorphisms of UCP2 and UCP3 on very low calorie diet-induced body fat reduction in Korean female subjects
    • Yoon Y, Park BL, Cha MH, Kim KS, Cheong HS, Choi YH et al. Effects of genetic polymorphisms of UCP2 and UCP3 on very low calorie diet-induced body fat reduction in Korean female subjects. Biochem Biophys Res Commun 2007;359:451-6.
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 451-456
    • Yoon, Y.1    Park, B.L.2    Cha, M.H.3    Kim, K.S.4    Cheong, H.S.5    Choi, Y.H.6
  • 32
    • 0031816020 scopus 로고    scopus 로고
    • Uncoupling protein-2 gene: reduced mRNA expression in intraperitoneal adipose tissue of obese humans
    • Oberkofler H, Liu YM, Esterbauer H, Hell E, Krempler F, Patsch W. Uncoupling protein-2 gene: reduced mRNA expression in intraperitoneal adipose tissue of obese humans. Diabetologia 1998;41:940-6.
    • (1998) Diabetologia , vol.41 , pp. 940-946
    • Oberkofler, H.1    Liu, Y.M.2    Esterbauer, H.3    Hell, E.4    Krempler, F.5    Patsch, W.6
  • 36
    • 7344220905 scopus 로고    scopus 로고
    • Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima Indians
    • Walder K, Norman RA, Hanson RL, Schrauwen P, Neverova M, Jenkinson CP et al. Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima Indians. Hum Mol Genet 1998;7:1431-5.
    • (1998) Hum Mol Genet , vol.7 , pp. 1431-1435
    • Walder, K.1    Norman, R.A.2    Hanson, R.L.3    Schrauwen, P.4    Neverova, M.5    Jenkinson, C.P.6


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