Physiological relationships of uncoupling protein-2 gene expression in human adipose tissue in vivo

Journal of Clinical Endocrinology and Metabolism

Volumn 85, Issue 6, 2000, Pages 2312-2317

  Pinkney, Jonathan H ^a,b   Boss, Olivier ^c   Bray, George A ^a   Bulmer, Karen ^d   Coppack, Simon W ^d   Mohamed Ali, Vidya ^d  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; INSULIN; MESSENGER RNA; NUCLEASE; UNCOUPLING PROTEIN 2; XENON 133;

ADIPOSE TISSUE; ADULT; ARTICLE; BODY FAT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; FATTY ACID BLOOD LEVEL; FEMALE; FOOD INTAKE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INSULIN BLOOD LEVEL; MALE; OBESITY; PATHOGENESIS; POSTPRANDIAL STATE; PRIORITY JOURNAL; RADIAL ARTERY;

EUKARYOTA;

EID: 0034455929     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.85.6.2312     Document Type: Article

References (34)

1. Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinaemia
2. Cloning and characterisation of an uncoupling protein homolog. A potential molecular mediator of human thermogenesis
3. 3-adrenoceptor agonist BRL 35135 on UCP isoform mRNA expression
4. Molecular cloning of rat uncoupling protein 2 cDNA and its expression in genetically obese Zucker (fa/fa) rats
5. 3-adrenergic agonist BRL 35135 and metformin in obese fa/fa Zucker rats
6. Differential regulation of mouse uncoupling proteins among brown adipose tissue, white adipose tissue, and skeletal muscle in chronic beta 3 adrenergic receptor agonist treatment
7. Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone and β3-adrenergic agonists and leptin
8. Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation
9. Leptin regulation of peroxisome proliferator-activated receptor-γ, tumor necrosis factor, and uncoupling protein-2 expression in adipose tissues
10. Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells
11. Cloning of rat uncouplin protein-3 and uncoupling protein-2 cDNAs: Their gene expression in rats fed high fat diet
12. Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice
13. Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans
14. Uncoupling protein-2 messenger ribonucleic acid expression durng very-low calorie diet in obese premenopausal women
15. Uncoupling protein-2 gene: Reduced mRNA expression in intraperitoneal adipose tissue of obese humans
16. Uncoupling protein-3: A new member of the mitochondrial carrier family with tissue-specific expression
17. UCP3: An uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
18. Uncoupling protein-3 expression in skeletal muscle and free fatty acids in obesity
19. Elevated free fatty acids induce uncoupling protein-3 expression in muscle
20. Role of UCP homologues in skeletal muscles and brown adipose tissue: Mediators of thermogenesis or regulators of lipids as fuel substrate?
21. Interorgan signaling between adipose tissue metabolism and skeletal muscle uncoupling protein homologs: Is there a role for circulating free fatty acids?
22. Metabolic characteristics of human adipsoe tissue in vivo
23. Tissue/blood partition coefficients for xenon in various adipose tissue depots in man
24. Subcutaneous abdominal adipose tissue blood flow: Variation within and between subjects and relationship to obesity
25. Adipose tissue leptin production and plasma leptin kinetics in humans
26. Effect of isoprenaline on plasma leptin and lipolysis in humans in vivo
27. Insulin clearance by adipose tissue in vivo
28. Regulation of the level of uncoupling protein in brown adipose tissue by insulin
29. Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins
30. Uncoupling protein-3: A muscle-specific gene upregulated by leptin on ob/ob mice
31. UCP2, UCP3 and leptin gene expression: Modulation by food restriction and leptin
32. Low plasma leptin in response to dietary fat in diabetes- and obesity-prone mice
33. Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes
34. Bidirectional regulation of uncoupling protein-3 and GLUT-4 mRNA in skeletal muscle by cold