Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy

Journal of Clinical Oncology

Volumn 21, Issue 5, 2003, Pages 927-931

  Pace, Andrea ^a   Savarese, Antonella ^a   Picardo, Mauro ^a   Maresca, Vittoria ^a   Pacetti, Umberto ^a   Del Monte, Girolamo ^a   Biroccio, Annamaria ^a   Leonetti, Carlo ^a   Jandolo, Bruno ^a   Cognetti, Francesco ^a   Bove, Loredana ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; CISPLATIN; ANTINEOPLASTIC AGENT; ANTIOXIDANT; NEUROPROTECTIVE AGENT;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER PATIENT; CLINICAL ARTICLE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; HUMAN; LIFESPAN; MELANOMA; MONOTHERAPY; MOUSE; MULTIPLE CYCLE TREATMENT; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; TUMOR VOLUME; VITAMIN SUPPLEMENTATION; ADULT; AGED; ANIMAL; CELL PROTECTION; CHEMICALLY INDUCED DISORDER; DIET SUPPLEMENTATION; DRUG COMBINATION; DRUG SCREENING; ELECTROPHYSIOLOGY; EXPERIMENTAL MELANOMA; FEMALE; MALE; MIDDLE AGED; NEOPLASM; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY;

ADULT; AGED; ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CISPLATIN; CYTOPROTECTION; DIETARY SUPPLEMENTS; DRUG EVALUATION, PRECLINICAL; DRUG THERAPY, COMBINATION; ELECTROPHYSIOLOGY; FEMALE; HUMANS; MALE; MELANOMA, EXPERIMENTAL; MICE; MIDDLE AGED; NEOPLASMS; NEUROPROTECTIVE AGENTS; PERIPHERAL NERVOUS SYSTEM DISEASES; VITAMIN E;

EID: 0037366026     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2003.05.139     Document Type: Article

References (26)

1. Hamers FPT, Gispen WH, Neijt JP: Neurotoxic side effects of cisplatin. Eur J Cancer 27(3):372-376, 1991
2. Alberts DS, Noel JK: Cisplatin-associated neurotoxicity: Can it be prevented? Anticancer Drugs 6:369-383, 1995
3. Cavaletti G, Tredici G, Marmiroli P: Morphometric study of the sensory neuron and peripheral nerve changes induced by chronic cisplatin (CDDP) administration in rats. Acta Neuropathol 84:364-371, 1992
4. Gregg RW, Matshela MJ, Monpetit VJA, et al.: Cisplatin Neurotoxicity: The relationship between dosage, time, and platinum concentration in neurological tissue and morphological evidence of toxicity. J Clin Oncol 10:795-803, 1992
5. Krarup-Hansen A, Rietz B, Krarup C, et al: Histology and platinum content of sensory ganglia and sural nerves in patients treated with cisplatin and carboplatin: An autopsy study. Neuropathol Appl Neurobiol 25(1):29-40, 1999
6. Windebank AJ, Gordon Smith A, Russel JW: The effect of nerve growth factor, ciliary neurotrophic factor, and ACTH analogs on cisplatin neurotoxicity in vitro. Neurology 44:488-494, 1994
7. Cascinu S, Cordella L, Del Ferro E, et al: Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: A randomized double-blind placebo-controlled trial. J Clin Oncol 13(1):26-32, 1995
8. Di Paola RS, Schuchter L.: Neurologic protection by Amifostine. Semin Oncol 26(suppl 7):82-88, 1999
9. Smoorenburg GF, De Groot JC, Hamers FP, et al: Protection and spontaneous recovery from cisplatin-induced hearing loss. Ann N Y Acad Sci 28, 884:192-210, 1999
10. Weijl NI, Hopman GD, Wipkink-Bakker A, et al: Cisplatin combination chemotherapy induces a fall in plasma antioxidants of cancer patients. Ann Oncol 9(12):1331-1337, 1998
11. Sugihara K, Gemba M: Modification of cisplatin toxicity by antioxidants. Jpn J Pharmacol 40(2):353-355, 1986
12. Appenroth D, et al: Protective effects of vitamin E and C on cisplatin nephrotoxicity in developing rats. Arch Toxicol 71:677, 1997
13. Rybak LP, Husain K, Morris C, et al: Effect of protective agents against cisplatin ototoxicity. Am J Otol 21(4):513-520, 2000
14. Traber MG, Sokol RJ, Ringel SP, et al: Lack of α-tocopherol in peripheral nerves of vitamin E deficient patients with peripheral neuropathy. N Engl J Med 317:262-265, 1987
15. Muller DPR, Lloid JK, Wolff OH: Vitamin E and neurological function. Lancet 29:225-228, 1983
16. Bove L, Picardo M, Maresca V, et al.: A Pilot study on the relationship between cisplatin neuropathy and Vitamin. E. J Exp Clin Cancer Res 20(2):277-280, 2001
17. Citro G, D'Agnano I, Leonetti C, et al: c-myc antisense oligodeoxynucleotides enhance the efficacy of cisplatin in melanoma chemotherapy in vitro and in nude mice. Cancer Res 58(2):283-289, 1998
18. Greco C, Zupi G: Biological features and in vitro chemosensitivity of a new model of human melanoma. Anticancer Res 7:839-844, 1987
19. Windebank AJ: Polineuropathy due to nutritional deficiency and alcoholism; in Dick PJ and Thomas PK (eds): Peripheral Neuropathy (ed 3). Vol 2. Philadelphia, PA, WB Saunders, 1993, pp 1310-1317
20. Pace A, Bove L, Aloe A, et al.: Paclitaxel neurotoxicity: Clinical and neurophysiological study in 23 patients. It J Neurol Sci 18:73-79, 1996
21. Chaudry V, Rowinsky EK, Sartorius et al.: Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studies. Ann Neurol 35:304-311, 1994
22. Pace A, Bove L, Nisticò C, et al: Vinorelbine neurotoxicity: Clinical and neurophysiological findings in 23 patients. J Neurol Neurosurg Psychiatry 61:409-411, 1996
23. Passi S, Morrone A, Picardo M, et al: Blood level of vitamin E, polyunsaturated fatty acids of phospholipids, lipoperoxides, and glutathione peroxidase activity in patients with seborrheic dermatitis. J Dermatol Sci 2:171-178, 1991
24. Vasigara Singh W, Subramaniam S, Shyama Subramaniam, et al: Levels of antioxidants in haemolysates from breast cancer patients after chemo- and radiotherapy. Med Sci Res 24:195-197, 1996
25. el Daly ES: Protective effect of cisteine and vitamin E, crocus sativa and Nigella sativa extracts on cisplatin-induced toxicity in rats. J Pharm Belg 53(2):87-93, 1998
26. Teranishi M, Nakashima T, Wakabayashi T: Effects of alfa-tocopherol on cisplatin-induced ototoxicity in guinea pigs. Hear Res 151(1-2):61-70, 2001