TLR9 polymorphisms and systemic lupus erythematosus risk in Asians: A meta-analysis study

Cytokine

Volumn 57, Issue 2, 2012, Pages 282-289

  Yang, Zaixing ^a   Liang, Yan ^a   Qin, Baodong ^a   Li, Chang ^a   Zhong, Renqian ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Meta analysis; Polymorphism; Systemic lupus erythematosus; Toll like receptor 9

Indexed keywords

ADENINE; CYTOSINE; GUANINE; THYMINE; TOLL LIKE RECEPTOR 9;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; ASIAN; CHINA; GENE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HONG KONG; HUMAN; JAPAN; MEDICAL LITERATURE; MEDICAL RESEARCH; POPULATION GENETICS; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH KOREA; SYSTEMATIC REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS; TLR9 GENE;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PUBLICATION BIAS; RISK FACTORS; TOLL-LIKE RECEPTOR 9;

EID: 84855444149     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2011.11.017     Document Type: Article

References (28)

1. Yasutomo K. Pathological lymphocyte activation by defective clearance of self ligands in systemic lupus erythematosus. Rheumatology (Oxford) 2003, 42:214-222.
2. Wakeland E.K., Liu K., Graham R.R., Behrens T.W. Delineating the genetic basis of systemic lupus erythematosus. Immunity 2001, 15:397-408.
3. Ruiz-Narvaez EA, Fraser PA, Palmer JR, Cupples LA, Reich D, Wang YA, Rioux JD, Rosenberg L. MHC region and risk of systemic lupus erythematosus in African American women. Hum Genet 2011; Epub ahead of print.
4. Lessard C.J., Adrianto I., Kelly J.A., et al. Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet 2011, 88:83-91.
5. Han J.W., Zheng H.F., Cui Y., et al. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet 2009, 41:1234-1237.
6. Klinman D.M., Yi A.K., Beaucage S.L., Conover J., Krieg A.M. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc Natl Acad Sci USA 1996, 93:2879-2883.
7. Leadbetter E.A., Rifkin I.R., Hohlbaum A.M., Beaudette B.C., Shlomchik M.J., Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 2002, 416:603-607.
8. Christensen S.R., Kashgarian M., Alexopoulou L., Flavell R.A., Akira S., Shlomchik M.J. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med 2005, 202:321-331.
9. Yu P., Musette P., Peng S.L. Toll-like receptor 9 in murine lupus: more friend than foe!. Immunobiology 2008, 213:151-157.
10. Takeda K., Kaisho T., Akira S. Toll-like receptors. Annu Rev Immunol 2003, 21:335-376.
11. Wu X., Peng S.L. Toll-like receptor 9 signaling protects against murine lupus. Arthritis Rheum 2006, 54:336-342.
12. Kelly J.A., Moser K.L., Harley J.B. The genetics of systemic lupus erythematosus: putting the pieces together. Genes Immun 2002, 3(Suppl. 1):S71-S85.
13. Higgins J.P., Thompson S.G. Quantifying heterogeneity in a meta-analysis. Stat Med 2002, 21:589-624.
14. Galbraith R.F. A note on graphical presentation of estimated odds ratios from several clinical trials. Stat Med 1988, 7:889-894.
15. Egger M., Davey S.G., Schneider M., Minder C. Bias in metaanalysis detected by a simple, graphical test. BMJ 1997, 315:629-634.
16. Begg C.B., Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994, 50:1088-1101.
17. De Jager P., Richardson A., Vyse T.J., Rioux J.D. Genetic variation in Toll-like receptor 9 and susceptibility to systemic lupus erythematosus. Arthritis Rheum 2006, 54:1279-1282.
18. Xu C.J., Zhang W.H., Pan H.F., Li X.P., Xu J.H., Ye D.Q. Association study of a single nucleotide polymorphism in the exon 2 region of toll-like receptor 9 (TLR9) gene with susceptibility to systemic lupus erythematosus among Chinese. Mol Biol Rep 2009, 36:2245-2248.
19. Demirci F.Y., Manzi S., Ramsey-Goldman R., et al. Association study of Toll-like receptor 5 (TLR5) and Toll-like receptor 9 (TLR9) polymorphisms in systemic lupus erythematosus. J Rheumatol 2007, 34:1708-1711.
20. Tao K., Fujii M., Tsukumo S., Maekawa Y., et al. Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population. Ann Rheum Dis 2007, 66:905-909.
21. Zhou X.J., Lv J.C., Cheng W.R., Yu L., Zhao M.H., Zhang H. Association of TLR9 gene polymorphisms with lupus nephritis in a Chinese Han population. Clin Exp Rheumatol 2010, 28:397-400.
22. Huang CM, Huang PH, Chen CL, Lin YJ, Tsai CH, Huang WL, Tsai FJ. Association of toll-like receptor 9 gene polymorphism in Chinese patients with systemic lupus erythematosus in Taiwan. Rheumatol Int 2011; [Epub ahead of print].
23. Ng M.W., Lau C.S., Chan T.M., Wong W.H., Lau Y.L. Polymorphisms of the toll-like receptor 9 (TLR9) gene with systemic lupus erythematosus in Chinese. Rheumatology (Oxford) 2005, 44:1456-1457.
24. Hur J.W., Shin H.D., Park B.L., Kim L.H., Kim S.Y., Bae S.C. Association study of Toll-like receptor 9 gene polymorphism in Korean patients with systemic lupus erythematosus. Tissue Antigens 2005, 65:266-270.
25. Lu Z.Y., Jin L.W., Niu Z.M., et al. Preliminary study on polymorphism of toll-like receptor 9 gene in patients with systemic lupus erythematosus. J Shanghai jiaotong university (Medical Science) 2007, 27:1448-1450.
26. Song W.Q., Li H.H., Chen H.B., Yuan J.S., Yin X.J. Relationship between polymorphism sites of IRF5, TLR-9 and SLE patients in Shandong Han population. Zhonghua Yi Xue Za Zhi 2009, 89:3038-3042.
27. Lazarus R., Klimecki W.T., Raby B.A., et al. Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three US ethnic groups and exploratory case-control disease association studies. Genomics 2003, 81:85-91.
28. Munafo M.R., Flint J. Meta-analysis of genetic association studies. Trends Genet 2008, 20:439-444.