Association study of Toll-like receptor 9 gene polymorphism in Korean patients with systemic lupus erythematosus

Tissue Antigens

Volumn 65, Issue 3, 2005, Pages 266-270

  Hur, J W ^a   Shin, H D ^b   Park, B L ^b   Kim, L H ^b   Kim, S Y ^c   Bae, Sang Cheol ^a,d  

^a Hanyang University Hospital for Rheumatic Diseases   (South Korea)

^b SNP Genetics Inc   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

^d Hanyang University Medical Center   (South Korea)

Author keywords

Polymorphism; Systemic lopus erythematosus; TLR9

Indexed keywords

TOLL LIKE RECEPTOR 9;

ADAPTIVE BEHAVIOR; ARTICLE; AUTOIMMUNE DISEASE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IMMUNITY; KOREA; MAJOR CLINICAL STUDY; MAMMAL; PHENOTYPE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; SYSTEMIC LUPUS ERYTHEMATOSUS; TLR9 GENE;

ADOLESCENT; ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; DNA-BINDING PROTEINS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; KOREA; LINKAGE DISEQUILIBRIUM; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 9;

LOPUS; MAMMALIA;

EID: 14844291442     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2005.00374.x     Document Type: Article

References (20)

1. Huck S, Deveaud E, Namane A, Zouali M. Abnormal DNA methylation and deoxycytosine-deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis. Faseb J 1999: 13: 1415-22.
2. Medzhitov R, Janeway C Jr. The Toll receptor family and microbial recognition. Trends Microbiol 2000: 8: 452-6.
3. Takeda K, Kaisho T, Akira S. Toll-like receptors. Annu Rev Immunol 2003: 21: 335-76.
4. Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001: 2: 675-80.
5. Kaisho T, Takeuchi O, Kawai T, Hoshino K, Akira S. Endotoxin-induced maturation of MyD88-deficient dendritic cells. J Immunol 2001: 166: 5688-94.
6. Hemmi H, Takeuchi O, Kawai T et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000: 408: 740-5.
7. Tsuji S, Matsumoto M, Takeuchi O et al. Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: involvement of toll-like receptors. Infect Immun 2000: 68: 6883-90.
8. Hertz CJ, Kiertscher SM, Godowski PJ et al. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J Immunol 2001: 166: 2444-50.
9. Michelsen KS, Aicher A, Mohaupt M et al. The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2. J Biol Chem 2001: 276: 25680-6.
10. Bauer S, Kirschning CJ, Hacker H et al. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc Natl Acad Sci USA 2001: 98: 9237-42.
11. Hamann L, Hamprecht A, Gomma A, Schumann RR. Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor -2, -4, and -9 genes. J Immunol Methods 2004: 285: 281-91.
12. Du X, Poltorak A, Wei Y, Beutler B. Three novel mammalian toll-like receptors: gene structure, expression, and evolution. Eur Cytokine Netw 2000: 11: 362-71.
13. Lazarus R, Klimecki WT, Raby BA et al. Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies. Genomics 2003: 81: 85-91.
14. Torok HP, Glas J, Tonenchi L, Bruennler G, Folwaczny M, Folwaczny C. Crohn's disease is associated with a toll-like receptor-9 polymorphism. Gastroenterology 2004: 127: 365-6.
15. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997: 40: 1725.
16. Gladman D, Ginzler E, Goldsmith C et al. The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for systemic lupus erythematosus. Arthritis Rheum 1996: 39: 363-9.
17. Livak KJ. Allelic discrimination using fluorogenic probes and the 5′ nuclease assay. Genet Anal 1999: 14: 143-9.
18. Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001: 68: 978-89.
19. Hedrick PW. Gametic disequilibrium measures: proceed with caution. Genetics 1987: 117: 331-41.
20. Hedrick P, Kumar S. Mutation and linkage disequilibrium in human mtDNA. Eur J Hum Genet 2001: 9: 969-72.