Relationship between polymorphism sites of IRF5, TLR-9 and SLE patients in Shandong Han population

National Medical Journal of China

Volumn 89, Issue 43, 2009, Pages 3038-3042

  Song, Wei Qing ^a   Li, Hua Hui ^a   Chen, Hua Bo ^a   Yuan, Jiang Shui ^a   Yin, Xiao Jie ^a  

^a QINGDAO MUNICIPAL HOSPITAL   (China)

Author keywords

IRF5; Single nucleotide polymorphism; SLE; TLR 9

Indexed keywords

INTERFERON REGULATORY FACTOR; IRF5 PROTEIN, HUMAN; TLR9 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 9;

ADOLESCENT; ADULT; AGED; ARTICLE; ASIAN; CASE CONTROL STUDY; ETHNOLOGY; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; HUMAN; MALE; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADOLESCENT; ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERFERON REGULATORY FACTORS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TOLL-LIKE RECEPTOR 9; YOUNG ADULT;

EID: 84871529853     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2009.43.005     Document Type: Article

References (12)

1. Baechler EC, Gregersen PK, Behrens TW. The emerging role of interferon in human systemic lupus erythematosus. Curr Opini Immunol, 2004, 16: 801-807.
2. Banchereau J, Pascual V. Type I Interferonin Systemic Lupus Erythematosus and Other Autoimmune Diseases. Immunity, 2006 , 25: 383-392.
3. Patole PS, Pawar RD, Lech M, et al. Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas ( lpr ) mice. Nephrol Dial Transplant, 2006, 21: 3062-3073.
4. Huang Q, Ma Y, Adebayo A, et al. Increased macrophage activation mediated through toll-like receptors in rheumatoid arthritis. Arthritis Rheum, 2007, 56: 2192-2201.
5. Graham RR, Kyogoku C, Sigurdsson S, et al. Three functional variants of IFN regulatory factor 5 ( IRF5 ) define risk and protective haplotypes for human lupus. PNAS, 2007, 104:6758-6763.
6. Armstrong DJ, Crockard AD, Wisdom BG, et al. Accelerated apoptosis in SLE neutrophils cultured with anti-dsDNA antibody isolated from SLE patient serum; a pilot study. Rheumatol Int, 2006, 27:153-156.
7. Santiago-Raber ML, Baccala R, Haraldsson KM, et al. Theofilopoulos AN:Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. J Exp Med, 2003, 197: 777-788.
8. Bengtsson AA, Sturfelt G, Truedsson L, et al. Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies. Lupus, 2000, 9: 664-671.
9. Shin HD, Sung YK, Choi CB, et al. Replication of the genetic effects of IFN regulatory factor 5 ( IRF5 ) on systemic lupus erythematosus in a Korean population. Arthritis Research Therapy, 2007, 9: R32-36.
10. De Jager PL, Richardson A, Vyse TJ,et al. Genetic variation in toll-like receptor 9 and susceptibility to systemic lupus erythematosus. Arthritis Rheum, 2006, 54: 1279-1282.
11. Hur JW, Shin HD, Park BL, et al. Association study of Toll-like receptor 9gene polymorphism in Korean patients with systemic lupus erythematosus. Tissue Antigens, 2005, 65: 266-270.
12. Tao K, Fujii M, Tsukumo S, et al. Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population. Ann Rheum Dis, 2007, 66: 905-909.