Association of TLR9 gene polymorphisms with lupus nephritis in a Chinese Han population

Clinical and Experimental Rheumatology

Volumn 28, Issue 3, 2010, Pages 397-400

  Zhou, Xu Jie ^a   Lv, Ji Cheng ^a   Cheng, Wen Rong ^a   Yu, Lei ^a   Zhao, Ming Hui ^a   Zhang, Hong ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Chinese; Lupus nephritis; TLR9

Indexed keywords

TOLL LIKE RECEPTOR 9; TLR9 PROTEIN, HUMAN;

ADULT; ALLELE; ARTICLE; CHINESE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE SEVERITY; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; POPULATION GENETICS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN; CHINA; ETHNOLOGY; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; HAPLOTYPE; IMMUNOLOGY; STATISTICS;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; LUPUS NEPHRITIS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; TOLL-LIKE RECEPTOR 9; YOUNG ADULT;

EID: 77957008935     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. KIM WU, SREIH A, BUCALA R: Toll-like receptors in systemic lupus erythematosus; prospects for therapeutic intervention. Autoimmun Rev 2009; 8: 204-8.
2. YU P, MUSETTE P, PENG SL: Toll-like receptor 9 in murine lupus: more friend than foe!. Immunobiology 2008; 213: 151-7.
3. SANCHEZ E, CALLEJAS-RUBIO JL, SABIO JM et al.: Investigation of TLR5 and TLR7 as candidate genes for susceptibility to systemic lupus erythematosus. Clin Exp Rheumatol 2009; 27: 267-71.
4. KAWAGOE T, TAKEUCHI O, TAKABATAKE Y et al.: TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat Immunol 2009; 10: 965-72.
5. BAGAVANT H, FU SM: Pathogenesis of kidney disease in systemic lupus erythematosus. Curr Opin Rheumatol 2009; 21: 489-94.
6. ROBSON MG: Toll-like receptors and renal disease. Nephron Exp Nephrol 2009; 113: e1-7.
7. ELEFTHERIADIS T, LAWSON BR: Toll-like receptors and kidney diseases. Inflamm Allergy Drug Targets 2009; 8: 191-201.
8. LARTIGUE A, COURVILLE P, AUQUIT I et al.: Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus. J Immunol 2006; 177: 1349-54.
9. ANDERS HJ, VIELHAUER V, EIS V et al.: Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice. FASEB J 2004; 18: 534-6.
10. BOULE MW, BROUGHTON C, MACKAY F, AKIRA S, MARSHAK-ROTHSTEIN A, RIFKIN IR: Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J Exp Med 2004; 199: 1631-40.
11. ANDERS HJ, BANAS B, LINDE Y et al.: Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors. J Am Soc Nephrol 2003; 14: 317-26.
12. PAPADIMITRAKI E, TZARDI M, BERTSIAS G, SOTSIOU E, BOUMPAS D: Glomerular expression of toll-like receptor-9 in lupus nephritis but not in normal kidneys: implications for the amplification of the inflammatory response. Lupus 2009; 18: 831-5.
13. XU CJ, ZHANG WH, PAN HF, LI XP, XU JH, YE DQ: Association study of a single nucleotide polymorphism in the exon 2 region of toll-like receptor 9 (TLR9) gene with susceptibility to systemic lupus erythematosus among Chinese. Mol Biol Rep 2009. 36: 2245-8.
14. TAO K, FUJII M, TSUKUMO S et al.: Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population. Ann Rheum Dis 2007; 66: 905-9.
15. DEMIRCI FY, MANZI S, RAMSEY-GOLDMAN R et al.: Association study of Toll-like receptor 5 (TLR5) and Toll-like receptor 9 (TLR9) polymorphisms in systemic lupus erythematosus. J Rheumatol 2007; 34: 1708-11.
16. DE JAGER PL, RICHARDSON A, VYSE TJ, RIOUX JD: Genetic variation in toll-like receptor 9 and susceptibility to systemic lupus erythematosus. Arthritis Rheum 2006; 54: 1279-82.
17. NG MW, LAU CS, CHAN TM, WONG WH, LAU YL: Polymorphisms of the toll-like receptor 9 (TLR9) gene with systemic lupus erythematosus in Chinese. Rheumatology (Oxford) 2005; 44: 1456-7.
18. HUR JW, SHIN HD, PARK BL, KIM LH, KIM SY, BAE SC: Association study of Toll-like receptor 9 gene polymorphism in Korean patients with systemic lupus erythematosus. Tissue Antigens 2005; 65: 266-70.
19. HOCHBERG MC: Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997; 40: 1725.
20. ANDERS HJ, SCHLONDORFF D: Toll-like receptors: emerging concepts in kidney disease. Curr Opin Nephrol Hypertens 2007; 16: 177-83.
21. AMITAL H, GOVONI M, MAYA R et al.: Role of infectious agents in systemic rheumatic diseases. Clin Exp Rheumatol 2008; 26 (Suppl. 48): S27-32.
22. AVCIN T, CANOVA M, GUILPAIN P et al.: Infections, connective tissue diseases and vasculitis. Clin Exp Rheumatol 2008; 26 (Suppl. 48): S18-26.
23. ALLAM R, LICHTNEKERT J, MOLL AG, TAUBITZ A, VIELHAUER V, ANDERS HJ: Viral RNA and DNA trigger common antiviral responses in mesangial cells. J Am Soc Nephrol 2009; 20: 1986-96.