Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles

Gene Expression Patterns

Volumn 5, Issue 6, 2005, Pages 750-755

  Benedito, Rui ^a   Duarte, António ^a  

^a FACULDADE DE MEDICINA VETERINÁRIA   (Portugal)

Author keywords

Angiogenesis; Dll4; Embryonic expression; Neural development; Notch signalling

Indexed keywords

BETA GALACTOSIDASE; DELTA LIKE 4 PROTEIN; MEMBRANE PROTEIN; NOTCH RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; CARDIOVASCULAR SYSTEM; CELL FATE; CHROMAFFIN SYSTEM; CONTROLLED STUDY; DIGESTIVE SYSTEM; EMBRYO; EMBRYO DEVELOPMENT; ENDOCARDIUM; ENDOTHELIUM CELL; GENE CASSETTE; GENE EXPRESSION; GENE FUNCTION; HEART MUSCLE CELL; INTESTINE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL TUBE; NONHUMAN; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; REPORTER GENE; RETINA; SIGNAL TRANSDUCTION; THYMUS; VASCULAR SMOOTH MUSCLE; VOMERONASAL ORGAN;

ANIMALS; BLOOD VESSELS; EMBRYONIC DEVELOPMENT; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MEMBRANE PROTEINS; MICE; NERVOUS SYSTEM; OLFACTORY PATHWAYS; RETINA;

EID: 21744442626     PISSN: 1567133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.modgep.2005.04.004     Document Type: Article

References (16)

1. S. Artavanis-Tsakonas M.D. Rand R.J. Lake Notch signaling: Cell fate control and signal integration in development Science 284 1999 770-776
2. E. Cau G. Gradwohl S. Casarosa R. Kageyama F. Guillemot Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium Development 127 2000 2323-2332
3. S. Claxton M. Fruttiger Periodic Delta-like 4 expression in developing retinal arteries Gene Expr. Patterns 5 2004 123-127
4. A. Duarte M. Hirashima R. Benedito A. Trindade P. Diniz E. Bekman et al. Dosage-sensitive requirement for mouse Dll4 in artery development Genes Dev. 18 2004 2474-2478
5. S.L. Dunwoodie D. Henrique S.M. Harrison R.S. Beddington Mouse Dll3: A novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo Development 124 1997 3065-3076
6. N.W. Gale M.G. Dominguez I. Noguera L. Pan V. Hughes D.M. Valenzuela et al. Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development Proc. Natl Acad. Sci. USA 101 2004 15949-15954
7. B. Hogan R. Beddington F. Constantini E. Lacy Manipulating the Mouse Embryo. A Laboratory Manual 1994 Cold Spring Harbor Laboratory Press, New york
8. D.E. Jackson The unfolding tale of PECAM-1 FEBS Lett. 540 2003 7-14
9. J. Jensen E.E. Pedersen P. Galante J. Hald R.S. Heller M. Ishibashi et al. Control of endodermal endocrine development by Hes-1 Nat. Genet. 24 2000 36-44
10. L.T. Krebs J.R. Shutter K. Tanigaki T. Honjo K.L. Stark T. Gridley Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants Genes Dev. 18 2004 2469-2473
11. C. Mailhos U. Modlich J. Lewis A. Harris R. Bicknell D. Ish-Horowicz Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis Differentiation 69 2001 135-144
12. A. Myat D. Henrique D. Ish-Horowicz J. Lewis A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis Dev. Biol. 174 1996 233-247
13. J.R. Shutter S. Scully W. Fan W.G. Richards J. Kitajewski G.A. Deblandre et al. Dll4, a novel Notch ligand expressed in arterial endothelium Genes Dev. 14 2000 1313-1318
14. E. Smith M. Hargrave T. Yamada C.G. Begley M.H. Little Coexpression of SCL and GATA3 in the V2 interneurons of the developing mouse spinal cord Dev. Dyn. 224 2002 231-237
15. Y. Suzuki I. Mizoguchi H. Nishiyama M. Takeda N. Obara Expression of Hes6 and NeuroD in the olfactory epithelium, vomeronasal organ and non-sensory patches Chem. Senses 28 2003 197-205
16. H.U. Wang Z.F. Chen D.J. Anderson Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4 Cell 93 1998 741-753