Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299

Journal Pharmacological Sciences

Volumn 91, Issue 2, 2003, Pages 95-104

  Jang, Mi Hyeon ^a   Shin, Min Chul ^a   Lim, Sabina ^b   Han, Seung Moo ^b   Park, Hi Joon ^b   Shin, Insop ^b   Lee, Ji Suk ^b   Kim, Kyoung Ah ^b   Kim, Ee Hwa ^c   Kim, Chang Ju ^a,b  

^a Kyung Hee University Hospital   (South Korea)

^b Kyung Hee University   (South Korea)

^c Semyung University   (South Korea)

Author keywords

Apoptosis; Bee venom; Cyclooxygenase; Lung cancer; Prostaglandin E2

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACETYLSALICYLIC ACID; BEE VENOM; CASPASE 3; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOPHILIN; DNA; DNA FRAGMENT; MESSENGER RNA; PROSTAGLANDIN E2; PROTEIN BAX; PROTEIN BCL 2;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASSAY; BIOCHEMISTRY; CANCER CELL CULTURE; CONTROLLED STUDY; DNA DETERMINATION; DRUG SELECTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOASSAY; LUNG CANCER; NICK END LABELING; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING;

EID: 0037716618     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.91.95     Document Type: Article

References (37)

1. 2 adrenoceptors. Neurosci Lett 308, 133-137 (2001)
2. Kwon YB, Lee JD, Lee HJ, Han HJ, Mar WC, Kang SK, Beitz AJ and Lee JH: Bee venom injection into an acupuncture point reduces arthritis associated edema and nociceptive responses. Pain 90, 271-280 (2001)
3. 2 from bee (apis mellifera) venom cause necrosis of murine skeletal muscle in vivo. Toxicon 35, 67-80 (1997)
4. Liu P, Davis P, Liu H and Krishnan TR: Evaluation of cytotoxicity and absorption enhancing effects of melittin-a novel absorption enhancer. Eur J Pharm Biopharm 48, 85-87 (1999)
5. Vento R, D'Alessandro N, Giuliano M, Lauricella M, Carabillò M and Tesoriere G: Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: Involvement of oxidative stress. Exp Eye Res 70, 503-517 (2000)
6. Winder D, Gunzburg WH, Erfle V and Salmons B: Expression of antimicrobial peptides has an antitumour effect in human cells. Biochem Biophys Res Commun 242, 608-612 (1998)
7. Shin SY, Lee MK, Kim KL and Halm KS: Structure-antitumor and hemolytic activity relationships of synthetic peptides derived from cecropin A-magainin 2 and cecropin A-melittin hybrid peptides. J Pept Res 50, 279-285 (1997)
8. Kagawa S, Gu J, Swisher SG, Ji L, Roth JA, Lai D, Stephens LC and Fang B: Antitumor effect of adenovirus-mediated bax gene transfer on p53-sensitive and p53-resistant cancer lines. Cancer Res 60, 1157-1161 (2000)
9. Rao CV, Rivenson A, Simi B, Zang E, Kelloff G, Steele V and Reddy BS: Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent. Cancer Res 55, 1464-1472 (1995)
10. Chan TA, Morin PJ, Vogelstein B and Kinzler KW: Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. Proc Natl Acad Sci USA 95, 681-686 (1998)
11. Shiff SJ, Qiao L, Tasi LL and Rigas B: Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells. J Clin Invest 96, 491-503 (1995)
12. Hanif R, Pittas A, Feng Y, Koutsos MI, Qiao L, Staiano-Coico L, Shiff SI and Rigas B: Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway. Biochem Pharmacol 52, 237-245 (1996)
13. Thun MJ, Namboodiri MM and Heath CW Jr: Aspirin use and reduce risk of fatal colon cancer. N Engl J Med 325, 1593-1596 (1991)
14. Harris RE, Namboodiri KK and Farrar WB: Nonsteroidal anti-inflammatory drugs and breast cancer. Epidemiology 7, 203-205 (1996)
15. Schreinemachers DM and Everson RB: Aspirin use and lung, colon, and breast cancer incidence in a prospective study. Epidemiology 5, 138-146 (1994)
16. Klampfer L, Cammenga J, Wisniewski HG and Nimer SD: Sodium salicylate activates caspases and induces apoptosis of myeloid leukemia cell lines. Blood 93, 2386-2394 (1999)
17. Kerr JF, Winteford CM and Harmon BV: Apoptosis. Its significance in cancer and cancer therapy. Cancer 73, 2013-2026 (1994).
18. Woodle ES and Kulkarni S: Programmed cell death. Transplantation 66, 681-691 (1998)
19. Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462 (1995)
20. Korsmeyer SJ: Bcl-2 gene family and the regulation of programmed cell death. Cancer Res Suppl 59, 1693s-1700s (1999)
21. Cohen GM: Caspases: The executioners of apoptosis. Biochem J 326, 1-16 (1997)
22. Oltvai ZN, Milliman CL and Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death. Cell 74, 609-619 (1993)
23. Wardlaw S, March TH and Belinsky SA: Cyclooxygenase-2 expression is abundant in alveolar type II cells in lung cancer-sensitive mouse strains and in premalignant lesions. Carcinogenesis 21, 1371-1377 (2000)
24. Soriano AF, Helfrich B, Chan DC, Heasley LE, Bunn PA Jr and Chou TC: Synergistic effects of new chemopreventive agents and conventional cytotoxic agents against human lung cancer cell lines. Cancer Res 59, 6178-6184 (1999)
25. Subbaramaiah K, Zakim D, Weksler BB and Dannenberg AJ: Inhibition of cyclooxygenase: A novel approach to cancer prevention. Proc Soc Exp Biol Med 216, 201-210 (1997)
26. Herschman HR: Prostaglandin synthase 2. Biochim Biophys Acta 1299, 125-140 (1996)
27. Piazza GA, Alberts DS, Hixson LJ, Paranka NS, Li H, Finn T, Bogert C, Guillen JM, Brendel K, Gross PH, Sperl G, Ritchie J, Burt RW, Ellsworth L, Ahnen DJ and Pamukcu R: Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels. Cancer Res 57, 2909-2915 (1997)
28. Thompson HJ, Jiang C, Lu J, Mehta RG, Piazza GA, Paranka NS, Pamukcu R and Ahnene DJ: Sulfone metabolite of sulindac inhibits mammary carcinogenesis. Cancer Res 57, 267-271 (1997)
29. Hla T and Neilson K: Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci USA 89, 7384-7388 (1992)
30. Funk CD, Funk LB, Kennedy ME, Pong AS and Fitzgerald GA: Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chrosomal assignment. Faseb J 5, 2304-2312 (1991)
31. Sawa A, Oyama F, Cairns NJ, Amano N and Matsushita M: Aberrant expression of bcl-2 gene family in Down's syndrome brains. Mol Brain Res 48, 53-59 (1997)
32. Zhang GS, Tu CQ, Zhang GY, Zhou GB and Zheng WL: Indomethacin induces apoptosis and inhibits proliferation in chronic myeloid leukemia cells. Leuk Res 24, 385-392 (2000)
33. + cord blood cells is linked to apoptosis after growth factor withdrawal. Exp Hematol 28, 907-915 (2000)
34. Qiao L, Hanif R, Sphicas E, Shiff SJ and Rigas B: Effect of aspirin on induction of apoptosis on HT-29 human colon adenocarcinoma cells. Biochem Pharmacol 55, 53-64 (1998)
35. Cohen JJ: Apoptosis. Immuno Today 14, 126-130 (1993)
36. Reed JC: Double identity for proteins of the bcl-2 family. Nature 387, 773-776 (1997)
37. Wolff H, Saukkonen K, Anttila S, Karjalainen A, Vainio H, Ristimaki A: Expression of cyclooxygenase-2 in human lung carcinoma. Cancer Res 58, 4997-5001 (1998)