-
2
-
-
51649093834
-
Recent advances in head and neck cancer
-
Haddad RI, Shin DM. Recent advances in head and neck cancer. N Engl J Med 2008;359:1143-54.
-
(2008)
N Engl J Med
, vol.359
, pp. 1143-1154
-
-
Haddad, R.I.1
Shin, D.M.2
-
3
-
-
60249087574
-
Survival following primary surgery for oral cancer
-
Rogers SN, Brown JS, Woolgar JA, Lowe D, Magennis P, Shaw RJ, et al. Survival following primary surgery for oral cancer. Oral Oncol 2009;45:201-11.
-
(2009)
Oral Oncol
, vol.45
, pp. 201-211
-
-
Rogers, S.N.1
Brown, J.S.2
Woolgar, J.A.3
Lowe, D.4
Magennis, P.5
Shaw, R.J.6
-
4
-
-
80052177544
-
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
-
Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011;333:1154-7.
-
(2011)
Science
, vol.333
, pp. 1154-1157
-
-
Agrawal, N.1
Frederick, M.J.2
Pickering, C.R.3
Bettegowda, C.4
Chang, K.5
Li, R.J.6
-
5
-
-
80052158097
-
The mutational landscape of head and neck squamous cell carcinoma
-
Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, et al. The mutational landscape of head and neck squamous cell carcinoma. Science 2011;333:1157-60.
-
(2011)
Science
, vol.333
, pp. 1157-1160
-
-
Stransky, N.1
Egloff, A.M.2
Tward, A.D.3
Kostic, A.D.4
Cibulskis, K.5
Sivachenko, A.6
-
6
-
-
33646537475
-
Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma
-
DOI 10.1101/gad.1413306
-
Lu SL, Herrington H, Reh D, Weber S, Bornstein S, Wang D, et al. Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma. Genes Dev 2006;20:1331-42. (Pubitemid 43727593)
-
(2006)
Genes and Development
, vol.20
, Issue.10
, pp. 1331-1342
-
-
Lu, S.-L.1
Herrington, H.2
Reh, D.3
Weber, S.4
Bornstein, S.5
Wang, D.6
Li, A.G.7
Tang, C.-F.8
Siddiqui, Y.9
Nord, J.10
Andersen, P.11
Corless, C.L.12
Wang, X.-J.13
-
7
-
-
0032478998
-
Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
-
Rubin Grandis J, Melhem MF, Gooding WE, Day R, Holst VA, Wagener MM, et al. Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998;90:824-32. (Pubitemid 28280548)
-
(1998)
Journal of the National Cancer Institute
, vol.90
, Issue.11
, pp. 824-832
-
-
Grandis, J.R.1
Melhem, M.F.2
Gooding, W.E.3
Day, R.4
Holst, V.A.5
Wagener, M.M.6
Drenning, S.D.7
Tweardy, D.J.8
-
8
-
-
67349108318
-
Dysregulated molecular networks in head and neck carcinogenesis
-
Molinolo AA, Amornphimoltham P, Squarize CH, Castilho RM, Patel V, Gutkind JS. Dysregulated molecular networks in head and neck carcinogenesis. Oral Oncol 2009;45:324-34.
-
(2009)
Oral Oncol
, vol.45
, pp. 324-334
-
-
Molinolo, A.A.1
Amornphimoltham, P.2
Squarize, C.H.3
Castilho, R.M.4
Patel, V.5
Gutkind, J.S.6
-
9
-
-
70449651958
-
Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway
-
Hoover AC, Strand GL, Nowicki PN, Anderson ME, Vermeer PD, Klingelhutz AJ, et al. Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway. Oncogene 2009;28:3960-70.
-
(2009)
Oncogene
, vol.28
, pp. 3960-3970
-
-
Hoover, A.C.1
Strand, G.L.2
Nowicki, P.N.3
Anderson, M.E.4
Vermeer, P.D.5
Klingelhutz, A.J.6
-
10
-
-
0035124085
-
Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappaB signal pathways
-
Bancroft CC, Chen Z, Dong G, Sunwoo JB, Yeh N, Park C, et al. Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEKMAPK and IKK-NF-kappaB signal pathways. Clin Cancer Res 2001;7:435-42. (Pubitemid 32183050)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.2
, pp. 435-442
-
-
Bancroft, C.C.1
Chen, Z.2
Dong, G.3
Sunwoo, J.B.4
Yeh, N.5
Park, C.6
Van Waes, C.7
-
11
-
-
79952767543
-
Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance
-
Wang SJ, Bourguignon LY. Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance. Am J Pathol 2011;178:956-63.
-
(2011)
Am J Pathol
, vol.178
, pp. 956-963
-
-
Wang, S.J.1
Bourguignon, L.Y.2
-
12
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
DOI 10.1073/pnas.0610117104
-
Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, Dalerba P, et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci U S A 2007;104:973-8. (Pubitemid 46154721)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
Wolf, G.T.4
Kaplan, M.J.5
Dalerba, P.6
Weissman, I.L.7
Clarke, M.F.8
Ailles, L.E.9
-
13
-
-
43049165453
-
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
-
DOI 10.1016/j.cell.2008.03.027, PII S0092867408004443
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008;133:704-15. (Pubitemid 351636299)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
Eaton, E.Ng.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
14
-
-
73349134974
-
Hyaluronan-CD44 Interactions in cancer: Paradoxes and possibilities
-
Toole BP. Hyaluronan-CD44 Interactions in cancer: paradoxes and possibilities. Clin Cancer Res 2009;15:7462-8.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7462-7468
-
-
Toole, B.P.1
-
15
-
-
0036896923
-
CD44 is required for two consecutive steps in HGF/c-Met signaling
-
DOI 10.1101/gad.242602
-
Orian-Rousseau V, Chen L, Sleeman JP, Herrlich P, Ponta H. CD44 is required for two consecutive steps in HGF/c-Met signaling. Genes Dev 2002;16:3074-86. (Pubitemid 35424194)
-
(2002)
Genes and Development
, vol.16
, Issue.23
, pp. 3074-3086
-
-
Orian-Rousseau, V.1
Chen, L.2
Sleeman, J.P.3
Herrlich, P.4
Ponta, H.5
-
17
-
-
46149089421
-
Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression
-
DOI 10.1016/j.cell.2008.06.006, PII S009286740800754X
-
Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, et al. Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell 2008;134:62-73. (Pubitemid 351905743)
-
(2008)
Cell
, vol.134
, Issue.1
, pp. 62-73
-
-
Godar, S.1
Ince, T.A.2
Bell, G.W.3
Feldser, D.4
Donaher, J.L.5
Bergh, J.6
Liu, A.7
Miu, K.8
Watnick, R.S.9
Reinhardt, F.10
McAllister, S.S.11
Jacks, T.12
Weinberg, R.A.13
-
18
-
-
33745606029
-
A positive feedback loop couples Ras activation and CD44 alternative splicing
-
DOI 10.1101/gad.1430906
-
Cheng C, Yaffe MB, Sharp PA. A positive feedback loop couples Ras activation and CD44 alternative splicing. Genes Dev 2006;20:1715-20. (Pubitemid 43992879)
-
(2006)
Genes and Development
, vol.20
, Issue.13
, pp. 1715-1720
-
-
Cheng, C.1
Yaffe, M.B.2
Sharp, P.A.3
-
19
-
-
79952227361
-
CD44 splice isoformswitching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression
-
Brown RL, Reinke LM, Damerow MS, Perez D, Chodosh LA, Yang J, et al. CD44 splice isoformswitching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest 2011;121:1064-74.
-
(2011)
J Clin Invest
, vol.121
, pp. 1064-1074
-
-
Brown, R.L.1
Reinke, L.M.2
Damerow, M.S.3
Perez, D.4
Chodosh, L.A.5
Yang, J.6
-
20
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B, Chen X, Calhoun-Davis T, Li H, et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 2011;17:211-5.
-
(2011)
Nat Med
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
Chen, X.4
Calhoun-Davis, T.5
Li, H.6
-
21
-
-
83555172386
-
Frequency of cells expressing CD44, a Head and Neck cancer stem cell marker: Correlation with tumor aggressiveness
-
Joshua B, Kaplan MJ, Doweck I, Pai R, Weissman IL, Prince ME, et al. Frequency of cells expressing CD44, a Head and Neck cancer stem cell marker: correlation with tumor aggressiveness. Head Neck 2011.
-
(2011)
Head Neck
-
-
Joshua, B.1
Kaplan, M.J.2
Doweck, I.3
Pai, R.4
Weissman, I.L.5
Prince, M.E.6
-
22
-
-
78049452311
-
CD44 expression predicts local recurrence after radiotherapy in larynx cancer
-
deJong MC, Pramana J, van der Wal JE, Lacko M, Peutz-Kootstra CJ, de Jong JM, et al. CD44 expression predicts local recurrence after radiotherapy in larynx cancer. Clin Cancer Res 2010;16:5329-38.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5329-5338
-
-
DeJong, M.C.1
Pramana, J.2
Van Der Wal, J.E.3
Lacko, M.4
Peutz-Kootstra, C.J.5
De Jong, J.M.6
-
23
-
-
0034694024
-
Requirement of the chemokine receptor CXCR3 for acute allograft rejection
-
Hancock WW, Lu B, Gao W, Csizmadia V, Faia K, King JA, et al. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. J Exp Med 2000;192:1515-20.
-
(2000)
J Exp Med
, vol.192
, pp. 1515-1520
-
-
Hancock, W.W.1
Lu, B.2
Gao, W.3
Csizmadia, V.4
Faia, K.5
King, J.A.6
-
24
-
-
0032493649
-
Regulation of CD44 gene expression by the proinflammatory cytokine interleukin-1beta in vascular smooth muscle cells
-
DOI 10.1074/jbc.273.32.20341
-
Foster LC, Arkonac BM, Sibinga NE, Shi C, Perrella MA, Haber E. Regulation of CD44 gene expression by the proinflammatory cytokine interleukin-1beta in vascular smooth muscle cells. J Biol Chem 1998;273:20341-6. (Pubitemid 28377598)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.32
, pp. 20341-20346
-
-
Foster, L.C.1
Arkonac, B.M.2
Sibinga, N.E.S.3
Shi, C.4
Perrella, M.A.5
Haber, E.6
-
25
-
-
4344620189
-
Mek1 alters epidermal growth and differentiation
-
DOI 10.1158/0008-5472.CAN-04-0017
-
Scholl FA, Dumesic PA, Khavari PA. Mek1 alters epidermal growth and differentiation. Cancer Res 2004;64:6035-40. (Pubitemid 39129401)
-
(2004)
Cancer Research
, vol.64
, Issue.17
, pp. 6035-6040
-
-
Scholl, F.A.1
Dumesic, P.A.2
Khavari, P.A.3
-
26
-
-
34248192422
-
Loss of p53 expression correlates with metastatic phenotype and transcriptional profile in a new mouse model of head and neck cancer
-
DOI 10.1158/1541-7786.MCR-06-0238
-
Ku TK, Nguyen DC, Karaman M, Gill P, Hacia JG, Crowe DL. Loss of p53 expression correlates with metastatic phenotype and transcriptional profile in a new mouse model of head and neck cancer. Mol Cancer Res 2007;5:351-62. (Pubitemid 46706997)
-
(2007)
Molecular Cancer Research
, vol.5
, Issue.4
, pp. 351-362
-
-
Ku, T.K.S.1
Nguyen, D.C.2
Karaman, M.3
Gill, P.4
Hacia, J.G.5
Crowe, D.L.6
-
27
-
-
77949400528
-
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines
-
Brenner JC, Graham MP, Kumar B, Saunders LM, Kupfer R, Lyons RH, et al. Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines. Head Neck 2010;32:417-26.
-
(2010)
Head Neck
, vol.32
, pp. 417-426
-
-
Brenner, J.C.1
Graham, M.P.2
Kumar, B.3
Saunders, L.M.4
Kupfer, R.5
Lyons, R.H.6
-
28
-
-
34347343933
-
ABIN-3: A molecular basis for species divergence in interleukin-10- induced anti-inflammatory actions
-
DOI 10.1128/MCB.00223-07
-
Weaver BK, Bohn E, Judd BA, Gil MP, Schreiber RD. ABIN-3: a molecular basis for species divergence in interleukin-10-induced anti-inflammatory actions. Mol Cell Biol 2007;27:4603-16. (Pubitemid 47016116)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.13
, pp. 4603-4616
-
-
Weaver, B.K.1
Bohn, E.2
Judd, B.A.3
Gil, M.P.4
Schreiber, R.D.5
-
29
-
-
0022527161
-
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
-
Quintanilla M, Brown K, Ramsden M, Balmain A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 1986;322:78-80. (Pubitemid 16061512)
-
(1986)
Nature
, vol.322
, Issue.6074
, pp. 78-80
-
-
Quintanilla, M.1
Brown, K.2
Ramsden, M.3
Balmain, A.4
-
30
-
-
42649137241
-
Mechanisms of disease: Epithelial-mesenchymal transition - Does cellular plasticity fuel neoplastic progression?
-
DOI 10.1038/ncponc1089, PII NCPONC1089
-
Turley EA, Veiseh M, Radisky DC, Bissell MJ. Mechanisms of disease: epithelial-mesenchymal transition - does cellular plasticity fuel neoplastic progression? Nat Clin Pract Oncol 2008;5:280-90. (Pubitemid 351594144)
-
(2008)
Nature Clinical Practice Oncology
, vol.5
, Issue.5
, pp. 280-290
-
-
Turley, E.A.1
Veiseh, M.2
Radisky, D.C.3
Bissell, M.J.4
-
31
-
-
0027524424
-
A link between ras and metastatic behavior of tumor cells: ras Induces CD44 promoter activity and leads to low-level expression of metastasis- specific variants of CD44 in CREF cells
-
Hofmann M, Rudy W, Gunthert U, Zimmer SG, Zawadzki V, Zoller M, et al. A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells. Cancer Res 1993;53:1516-21. (Pubitemid 23113222)
-
(1993)
Cancer Research
, vol.53
, Issue.7
, pp. 1516-1521
-
-
Hofmann, M.1
Rudy, W.2
Gunthert, U.3
Zimmer, S.G.4
Zawadzki, V.5
Zoller, M.6
Lichtner, R.B.7
Herrlich, P.8
Ponta, H.9
-
32
-
-
33846546485
-
Head and neck squamous cell carcinoma cell lines: Established models and rationale for selection
-
DOI 10.1002/hed.20478
-
Lin CJ, Grandis JR, Carey TE, Gollin SM, Whiteside TL, Koch WM, et al. Head and neck squamous cell carcinoma cell lines: established models and rationale for selection. Head Neck 2007;29:163-88. (Pubitemid 46167784)
-
(2007)
Head and Neck
, vol.29
, Issue.2
, pp. 163-188
-
-
Lin, C.J.1
Grandis, J.R.2
Carey, T.E.3
Gollin, S.M.4
Whiteside, T.L.5
Koch, W.M.6
Ferris, R.L.7
Lai, S.Y.8
-
33
-
-
34447302548
-
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines
-
DOI 10.1016/j.oraloncology.2006.09.001, PII S1368837506002478
-
White JS, Weissfeld JL, Ragin CC, Rossie KM, Martin CL, Shuster M, et al. The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines. Oral Oncol 2007;43:701-12. (Pubitemid 47058372)
-
(2007)
Oral Oncology
, vol.43
, Issue.7
, pp. 701-712
-
-
White, J.S.1
Weissfeld, J.L.2
Ragin, C.C.R.3
Rossie, K.M.4
Martin, C.L.5
Shuster, M.6
Ishwad, C.S.7
Law, J.C.8
Myers, E.N.9
Johnson, J.T.10
Gollin, S.M.11
-
34
-
-
78651041785
-
Experimental carcinogenesis in the cheek pouch of the Syrian hamster
-
Salley JJ. Experimental carcinogenesis in the cheek pouch of the Syrian hamster. J Dent Res 1954;33:253-62.
-
(1954)
J Dent Res
, vol.33
, pp. 253-262
-
-
Salley, J.J.1
-
35
-
-
70449338760
-
Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation
-
Bornstein S, White R, Malkoski S, Oka M, Han G, Cleaver T, et al. Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation. J Clin Invest 2009;119:3408-19.
-
(2009)
J Clin Invest
, vol.119
, pp. 3408-3419
-
-
Bornstein, S.1
White, R.2
Malkoski, S.3
Oka, M.4
Han, G.5
Cleaver, T.6
-
36
-
-
67650338317
-
Chemical carcinogenesis models for evaluating molecular-targeted prevention and treatment of oral cancer
-
Phila
-
Vitale-Cross L, Czerninski R, Amornphimoltham P, Patel V, Molinolo AA, Gutkind JS. Chemical carcinogenesis models for evaluating molecular-targeted prevention and treatment of oral cancer. Cancer Prev Res (Phila) 2009;2:419-22.
-
(2009)
Cancer Prev Res
, vol.2
, pp. 419-422
-
-
Vitale-Cross, L.1
Czerninski, R.2
Amornphimoltham, P.3
Patel, V.4
Molinolo, A.A.5
Gutkind, J.S.6
-
37
-
-
77956686420
-
Xenograft models of head and neck cancers
-
Sano D, Myers JN. Xenograft models of head and neck cancers. Head Neck Oncol 2009;1:32.
-
(2009)
Head Neck Oncol
, vol.1
, pp. 32
-
-
Sano, D.1
Myers, J.N.2
-
38
-
-
0033046904
-
Decreased expression of CD80 is a marker for increased tumorigenicity in a new murine model of oral squamous-cell carcinoma
-
DOI 10.1002/(SICI)1097-0215(19990730)82:3<377::AID-IJC11>3.0.CO;2-9
-
Thomas GR, Chen Z, Oechsli MN, Hendler FJ, Van Waes C. Decreased expression of CD80 is a marker for increased tumorigenicity in a new murine model of oral squamous-cell carcinoma. Int J Cancer 1999;82:377-84. (Pubitemid 29302979)
-
(1999)
International Journal of Cancer
, vol.82
, Issue.3
, pp. 377-384
-
-
Thomas, G.R.1
Chen, Z.2
Oechli, M.N.3
Hendler, F.J.4
Van Waes, C.5
-
39
-
-
39749192555
-
The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth
-
DOI 10.1128/JVI.02188-07
-
Spanos WC, Hoover A, Harris GF, Wu S, Strand GL, Anderson ME, et al. The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth. J Virol 2008;82:2493-500. (Pubitemid 351293550)
-
(2008)
Journal of Virology
, vol.82
, Issue.5
, pp. 2493-2500
-
-
Spanos, W.C.1
Hoover, A.2
Harris, G.F.3
Wu, S.4
Strand, G.L.5
Anderson, M.E.6
Klingelhutz, A.J.7
Hendriks, W.8
Bossler, A.D.9
Lee, J.H.10
-
40
-
-
67651232299
-
Animal models of cancer in the head and neck region
-
Kim S. Animal models of cancer in the head and neck region. Clin Exp Otorhinolaryngol 2009;2:55-60.
-
(2009)
Clin Exp Otorhinolaryngol
, vol.2
, pp. 55-60
-
-
Kim, S.1
-
41
-
-
33750379861
-
Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis
-
DOI 10.1128/MCB.00404-06
-
Jang JW, Boxer RB, Chodosh LA. Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis. Mol Cell Biol 2006;26:8109-21. (Pubitemid 44631009)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.21
, pp. 8109-8121
-
-
Jang, J.W.1
Boxer, R.B.2
Chodosh, L.A.3
-
42
-
-
79953240219
-
Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells
-
Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, et al. Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells. Sci Signal 2011;4:ra17.
-
(2011)
Sci Signal
, vol.4
-
-
Little, A.S.1
Balmanno, K.2
Sale, M.J.3
Newman, S.4
Dry, J.R.5
Hampson, M.6
-
44
-
-
0242298117
-
Molecular pathogenesis of head and neck squamous cell carcinoma
-
DOI 10.1007/s00405-003-0581-3
-
Hardisson D. Molecular pathogenesis of head and neck squamous cell carcinoma. Eur Arch Otorhinolaryngol 2003;260:502-8. (Pubitemid 37363578)
-
(2003)
European Archives of Oto-Rhino-Laryngology
, vol.260
, Issue.9
, pp. 502-508
-
-
Hardisson, D.1
-
45
-
-
0043091970
-
Mutations of the BRAF gene in squamous cell carcinoma of the head and neck
-
DOI 10.1038/sj.onc.1206705
-
Weber A, Langhanki L, Sommerer F, Markwarth A, Wittekind C, Tannapfel A. Mutations of the BRAF gene in squamous cell carcinoma of the head and neck. Oncogene 2003;22:4757-9. (Pubitemid 36976451)
-
(2003)
Oncogene
, vol.22
, Issue.30
, pp. 4757-4759
-
-
Weber, A.1
Langhanki, L.2
Sommerer, F.3
Markwarth, A.4
Wittekind, C.5
Tannapfel, A.6
-
46
-
-
0025732716
-
High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India
-
Saranath D, Chang SE, Bhoite LT, Panchal RG, Kerr IB, Mehta AR, et al. High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India. Br J Cancer 1991;63:573-8.
-
(1991)
Br J Cancer
, vol.63
, pp. 573-578
-
-
Saranath, D.1
Chang, S.E.2
Bhoite, L.T.3
Panchal, R.G.4
Kerr, I.B.5
Mehta, A.R.6
-
47
-
-
77949464718
-
From basic research to clinical development of MEK1/2 inhibitors for cancer therapy
-
Fremin C, Meloche S. From basic research to clinical development of MEK1/2 inhibitors for cancer therapy. J Hematol Oncol 2010;3:8.
-
(2010)
J Hematol Oncol
, vol.3
, pp. 8
-
-
Fremin, C.1
Meloche, S.2
-
48
-
-
73649124286
-
Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression
-
Chen H, Zhu G, Li Y, Padia RN, Dong Z, Pan ZK, et al. Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression. Cancer Res 2009;69:9228-35.
-
(2009)
Cancer Res
, vol.69
, pp. 9228-9235
-
-
Chen, H.1
Zhu, G.2
Li, Y.3
Padia, R.N.4
Dong, Z.5
Pan, Z.K.6
-
49
-
-
77950353276
-
ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motifdependent signaling events
-
Shin S, Dimitri CA, Yoon SO, Dowdle W, Blenis J. ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motifdependent signaling events. Mol Cell 2010;38:114-27.
-
(2010)
Mol Cell
, vol.38
, pp. 114-127
-
-
Shin, S.1
Dimitri, C.A.2
Yoon, S.O.3
Dowdle, W.4
Blenis, J.5
-
50
-
-
79959260166
-
Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas
-
Basu D, Montone KT, Wang LP, Gimotty PA, Hammond R, Diehl JA, et al. Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas. Cell Cycle 2011;10:2008-16.
-
(2011)
Cell Cycle
, vol.10
, pp. 2008-2016
-
-
Basu, D.1
Montone, K.T.2
Wang, L.P.3
Gimotty, P.A.4
Hammond, R.5
Diehl, J.A.6
|