Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression

European Neuropsychopharmacology

Volumn 22, Issue 2, 2012, Pages 143-152

  Leri, Francesco ^a   Zhou, Yan ^b   Carmichael, Brendan ^a   Cummins, Erin ^a   Kreek, Mary Jeanne ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Cocaine; Dopamine D2 receptor; Gene expression; Lateral hypothalamus; Methadone; Preprohypocretin preproorexin; Sensitization; Stereotypy; Striatum

Indexed keywords

COCAINE; DOPAMINE 2 RECEPTOR; MESSENGER RNA; METHADONE; OREXIN; PREPRODYNORPHIN; PREPROENKEPHALIN; PREPROHYPOCRETIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CAUDATE NUCLEUS; COCAINE DEPENDENCE; CONTROLLED STUDY; GENE EXPRESSION; LATERAL HYPOTHALAMUS; MALE; METHADONE TREATMENT; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PUTAMEN; RAT; SENSITIZATION; STEADY STATE; STEREOTYPY;

ANALGESICS, OPIOID; ANIMALS; BRAIN; COCAINE; COCAINE-RELATED DISORDERS; DISEASE MODELS, ANIMAL; DOPAMINE UPTAKE INHIBITORS; DRUG DELIVERY SYSTEMS; DYNORPHINS; GENE EXPRESSION; LOCOMOTION; MALE; METHADONE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, OPIOID, MU; RNA, MESSENGER; STEREOTYPED BEHAVIOR;

EID: 84855200692     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2011.06.003     Document Type: Article

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