Altered ratio of D1 and D2 dopamine receptors in mouse striatum is associated with behavioral sensitization to cocaine

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Thompson, Dawn ^a   Martini, Lene ^a   Whistler, Jennifer L ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR ASSOCIATED SORTING PROTEIN 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; GASP 1 PROTEIN, MOUSE; GASP-1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; ENDOCYTOSIS; LOCOMOTION; MOUSE; NONHUMAN; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; ANIMAL; ANIMAL BEHAVIOR; DOWN REGULATION; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

ANIMALIA; MUS;

ANIMALS; BEHAVIOR, ANIMAL; CARRIER PROTEINS; COCAINE; CORPUS STRIATUM; DOWN-REGULATION; MICE; MICE, KNOCKOUT; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2;

EID: 77956219271     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011038     Document Type: Article

References (37)

1. Fehr C, Yakushev I, Hohmann N, Buchholz HG, Landvogt C, et al. (2008) Association of low striatal dopamine d2 receptor availability with nicotine dependence similar to that seen with other drugs of abuse. Am J Psychiatry 165: 507-514.
2. Wang GJ, Volkow ND, Fowler JS, Logan J, Abumrad NN, et al. (1997) Dopamine D2 receptor availability in opiate-dependent subjects before and after naloxone-precipitated withdrawal. Neuropsychopharmacology 16: 174-182.
3. Hietala J, West C, Syvalahti E, Nagren K, Lehikoinen P, et al. (1994) Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence. Psychopharmacology (Berl) 116: 285-290.
4. Volkow ND, Wang GJ, Maynard L, Fowler JS, Jayne B, et al. (2002) Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study. Psychiatry Res 116: 163-172.
5. Volkow ND, Chang L, Wang GJ, Fowler JS, Ding YS, et al. (2001) Low level of brain dopamine D2 receptors in methamphetamine abusers: association with metabolism in the orbitofrontal cortex. Am J Psychiatry 158: 2015-2021.
6. Nader MA, Morgan D, Gage HD, Nader SH, Calhoun TL, et al. (2006) PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys. Nat Neurosci 9: 1050-1056.
7. Volkow ND, Fowler JS, Wolf AP (1991) Use of positron emission tomography to study cocaine in the human brain. NIDA Res Monogr 112: 168-179.
8. Hooks MS, Juncos JL, Justice JB, Jr., Meiergerd SM, Povlock SL, et al. (1994) Individual locomotor response to novelty predicts selective alterations in D1 and D2 receptors and mRNAs. J Neurosci 14: 6144-6152.
9. Czoty PW, Morgan D, Shannon EE, Gage HD, Nader MA (2004) Characterization of dopamine D1 and D2 receptor function in socially housed cynomolgus monkeys self-administering cocaine. Psychopharmacology (Berl) 174: 381-388.
10. Bartlett SE, Enquist J, Hopf FW, Lee JH, Gladher F, et al. (2005) Dopamine responsiveness is regulated by targeted sorting of D2 receptors. Proc Natl Acad Sci U S A 102: 11521-11526.
11. Whistler JL, Enquist J, Marley A, Fong J, Gladher F, et al. (2002) Modulation of postendocytic sorting of G protein-coupled receptors. Science 297: 615-620.
12. Chausmer AL, Katz JL (2001) The role of D2-like dopamine receptors in the locomotor stimulant effects of cocaine in mice. Psychopharmacology (Berl) 155: 69-77.
13. Kalivas PW, Duffy P (1990) Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens. Synapse 5: 48-58.
14. Robinson TE, Berridge KC (1993) The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev 18: 247-291.
15. Nestler EJ, Aghajanian GK (1997) Molecular and cellular basis of addiction. Science 278: 58-63.
16. White FJ, Kalivas PW (1998) Neuroadaptations involved in amphetamine and cocaine addiction. Drug Alcohol Depend 51: 141-153.
17. Chen JF, Aloyo VJ, Weiss B (1993) Continuous treatment with the D2 dopamine receptor agonist quinpirole decreases D2 dopamine receptors, D2 dopamine receptor messenger RNA and proenkephalin messenger RNA, and increases mu opioid receptors in mouse striatum. Neuroscience 54: 669-680.
18. Eilam D, Szechtman H (1989) Biphasic effect of D-2 agonist quinpirole on locomotion and movements. Eur J Pharmacol 161: 151-157.
19. Starke K, Gothert M, Kilbinger H (1989) Modulation of neurotransmitter release by presynaptic autoreceptors. Physiol Rev 69: 864-989.
20. Masri B, Salahpour A, Didriksen M, Ghisi V, Beaulieu JM, et al. (2008) Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics. Proc Natl Acad Sci U S A 105: 13656-13661.
21. Urban JD, Vargas GA, von Zastrow M, Mailman RB (2007) Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways. Neuropsychopharmacology 32: 67-77.
22. Sorensen G, Sager TN, Petersen JH, Brennum LT, Thogersen P, et al. (2008) Aripiprazole blocks acute self-administration of cocaine and is not selfadministered in mice. Psychopharmacology (Berl) 199: 37-46.
23. Bowers MS, McFarland K, Lake RW, Peterson YK, Lapish CC, et al. (2004) Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking. Neuron 42: 269-281.
24. Nestler EJ, Terwilliger RZ, Walker JR, Sevarino KA, Duman RS (1990) Chronic cocaine treatment decreases levels of the G protein subunits Gi alpha and Go alpha in discrete regions of rat brain. J Neurochem 55: 1079-1082.
25. Self DW, Terwilliger RZ, Nestler EJ, Stein L (1994) Inactivation of Gi and G(o) proteins in nucleus accumbens reduces both cocaine and heroin reinforcement. J Neurosci 14: 6239-6247.
26. Fontana D, Post RM, Weiss SR, Pert A (1993) The role of D1 and D2 dopamine receptors in the acquisition and expression of cocaine-induced conditioned increases in locomotor behavior. Behav Pharmacol 4: 375-387.
27. Cabib S, Castellano C, Cestari V, Filibeck U, Puglisi-Allegra S (1991) D1 and D2 receptor antagonists differently affect cocaine-induced locomotor hyperactivity in the mouse. Psychopharmacology (Berl) 105: 335-339.
28. Le AD, Tomkins D, Higgins G, Quan B, Sellers EM (1997) Effects of 5-HT3, D1 and D2 receptor antagonists on ethanol- and cocaine-induced locomotion. Pharmacol Biochem Behav 57: 325-332.
29. Halberda JP, Middaugh LD, Gard BE, Jackson BP (1997) DAD1- and DAD2- like agonist effects on motor activity of C57 mice: differences compared to rats. Synapse 26: 81-92.
30. Eilam D, Clements KV, Szechtman H (1991) Differential effects of D1 and D2 dopamine agonists on stereotyped locomotion in rats. Behav Brain Res 45: 117-124.
31. Czoty PW, Gage HD, Nader MA (2005) PET imaging of striatal dopamine D2 receptors in nonhuman primates: increases in availability produced by chronic raclopride treatment. Synapse 58: 215-219.
32. Kalivas PW, Duffy P (1995) D1 receptors modulate glutamate transmission in the ventral tegmental area. J Neurosci 15: 5379-5388.
33. Reid MS, Hsu K, Jr., Berger SP (1997) Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse 27: 95-105.
34. Boeuf J, Trigo JM, Moreau PH, Lecourtier L, Vogel E, et al. (2009) Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice. Eur J Neurosci 30: 860-868.
35. Martini L, Waldhoer M, Pusch M, Kharazia V, Fong J, et al. (2007) Ligandinduced down-regulation of the cannabinoid 1 receptor is mediated by the Gprotein-coupled receptor-associated sorting protein GASP1. Faseb J 21: 802-811.
36. Enquist J, Skroder C, Whistler JL, Leeb-Lundberg LM (2007) Kinins promote B2 receptor endocytosis and delay constitutive B1 receptor endocytosis. Mol Pharmacol 71: 494-507.
37. Martini L, Thompson D, Kharazia V, Whistler JL (2010) Differential Regulation of Behavioral Tolerance to WIN55,212-2 by GASP1,Neuropsychopharmacology, In press.