Steady-state methadone blocks cocaine seeking and cocaine-induced gene expression alterations in the rat brain

European Neuropsychopharmacology

Volumn 19, Issue 4, 2009, Pages 238-249

  Leri, Francesco ^a   Zhou, Yan ^b   Goddard, Benjamin ^a   Levy, AnneMarie ^a   Jacklin, Derek ^a   Kreek, Mary Jeanne ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Cocaine; ; Dopamine receptor; Hypocretin orexin; ; Methadone; ; Mu opioid receptor;

Indexed keywords

COCAINE; DOPAMINE 2 RECEPTOR; MESSENGER RNA; METHADONE; MU OPIATE RECEPTOR; OPIATE; OREXIN;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CAUDATE NUCLEUS; CONTROLLED STUDY; DRUG BLOOD LEVEL; GENE EXPRESSION; HORMONE BLOOD LEVEL; HYPOTHALAMUS; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PUTAMEN; RAT; SPRAGUE DAWLEY RAT; STEADY STATE; STIMULUS RESPONSE;

ACOUSTIC STIMULATION; ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; COCAINE; COCAINE-RELATED DISORDERS; CONDITIONING, CLASSICAL; CONDITIONING, OPERANT; DOPAMINE UPTAKE INHIBITORS; DRUG ADMINISTRATION SCHEDULE; DRUG DELIVERY SYSTEMS; DYNORPHINS; GENE EXPRESSION REGULATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LOCOMOTION; MALE; METHADONE; NEUROPEPTIDES; PHOTIC STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, OPIOID, MU; RNA, MESSENGER;

EID: 60749117166     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2008.09.004     Document Type: Article

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