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Volumn 43, Issue 12, 2011, Pages 669-675

Rottlerin enhances IL-1β-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells

Author keywords

Breast neoplasms; Cyclooxygenase 2; Interleukin 1 ; P38 mitogen activated protein kinases; RNA stability; Rottlerin

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C DELTA; ROTTLERIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84855185783     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2011.43.12.077     Document Type: Article
Times cited : (25)

References (38)
  • 2
    • 18444408375 scopus 로고    scopus 로고
    • COX-2: A molecular target for colorectal cancer prevention
    • Brown JR, DuBois RN. COX-2: a molecular target for colorectal cancer prevention. J Clin Oncol 2005;23:2840-55
    • (2005) J Clin Oncol , vol.23 , pp. 2840-2855
    • Brown, J.R.1    Dubois, R.N.2
  • 3
    • 36248967155 scopus 로고    scopus 로고
    • Effects of dietary salt on intrarenal angiotensin system, NAD(P)H oxidase, COX-2, MCP-1 and PAI-1 expressions and NF-kappaB activity in salt-sensitive and -resistant rat kidneys
    • Chandramohan G, Bai Y, Norris K, Rodriguez-Iturbe B, Vaziri ND. Effects of dietary salt on intrarenal angiotensin system, NAD(P)H oxidase, COX-2, MCP-1 and PAI-1 expressions and NF-kappaB activity in salt-sensitive and -resistant rat kidneys. Am J Nephrol 2008;28:158-67
    • (2008) Am J Nephrol , vol.28 , pp. 158-167
    • Chandramohan, G.1    Bai, Y.2    Norris, K.3    Rodriguez-Iturbe, B.4    Vaziri, N.D.5
  • 4
    • 0035869678 scopus 로고    scopus 로고
    • Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac
    • Chen WS, Wei SJ, Liu JM, Hsiao M, Kou-Lin J, Yang WK. Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac. Int J Cancer 2001;91:894-9
    • (2001) Int J Cancer , vol.91 , pp. 894-899
    • Chen, W.S.1    Wei, S.J.2    Liu, J.M.3    Hsiao, M.4    Kou-Lin, J.5    Yang, W.K.6
  • 5
    • 70449519966 scopus 로고    scopus 로고
    • Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation
    • Chiu WT, Shen SC, Chow JM, Lin CW, Shia LT, Chen YC. Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation. Neurobiol Dis 2010;37:118-29
    • (2010) Neurobiol Dis , vol.37 , pp. 118-129
    • Chiu, W.T.1    Shen, S.C.2    Chow, J.M.3    Lin, C.W.4    Shia, L.T.5    Chen, Y.C.6
  • 8
    • 0032951716 scopus 로고    scopus 로고
    • P38 mitogenactivated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes
    • Dean JL, Brook M, Clark AR, Saklatvala J. p38 mitogenactivated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J Biol Chem 1999;274:264-9
    • (1999) J Biol Chem , vol.274 , pp. 264-269
    • Dean, J.L.1    Brook, M.2    Clark, A.R.3    Saklatvala, J.4
  • 10
    • 1842425625 scopus 로고    scopus 로고
    • Prognostic impact of cyclooxygenase-2 in breast cancer
    • Denkert C, Winzer KJ, Hauptmann S. Prognostic impact of cyclooxygenase-2 in breast cancer. Clin Breast Cancer 2004;4:428-33
    • (2004) Clin Breast Cancer , vol.4 , pp. 428-433
    • Denkert, C.1    Winzer, K.J.2    Hauptmann, S.3
  • 12
    • 0028942661 scopus 로고
    • Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide
    • Feng L, Xia Y, Garcia GE, Hwang D, Wilson CB. Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide. J Clin Invest 1995;95: 1669-75
    • (1995) J Clin Invest , vol.95 , pp. 1669-1675
    • Feng, L.1    Xia, Y.2    Garcia, G.E.3    Hwang, D.4    Wilson, C.B.5
  • 13
    • 0029983843 scopus 로고    scopus 로고
    • Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): Rationale for selective inhibition and progress to date
    • Griswold DE, Adams JL. Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): rationale for selective inhibition and progress to date. Med Res Rev 1996;16:181-206
    • (1996) Med Res Rev , vol.16 , pp. 181-206
    • Griswold, D.E.1    Adams, J.L.2
  • 15
    • 33845696273 scopus 로고    scopus 로고
    • BK-induced COX-2 expression via PKC-deltadependent activation of p42/p44 MAPK and NF-kappaB in astrocytes
    • Hsieh HL, Wang HH, Wu CY, Jou MJ, Yen MH, Parker P, Yang CM. BK-induced COX-2 expression via PKC-deltadependent activation of p42/p44 MAPK and NF-kappaB in astrocytes. Cell Signal 2007;19:330-40
    • (2007) Cell Signal , vol.19 , pp. 330-340
    • Hsieh, H.L.1    Wang, H.H.2    Wu, C.Y.3    Jou, M.J.4    Yen, M.H.5    Parker, P.6    Yang, C.M.7
  • 16
    • 0033991143 scopus 로고    scopus 로고
    • Differential regulation of cyclooxygenase-2 (COX-2) mRNA stability by interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) in human in vitro differentiated macrophages
    • Huang ZF, Massey JB, Via DP. Differential regulation of cyclooxygenase-2 (COX-2) mRNA stability by interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) in human in vitro differentiated macrophages. Biochem Pharmacol 2000;59:187-94
    • (2000) Biochem Pharmacol , vol.59 , pp. 187-194
    • Huang, Z.F.1    Massey, J.B.2    Via, D.P.3
  • 17
    • 38849134824 scopus 로고    scopus 로고
    • Upregulation of cortical COX-2 in salt-sensitive hypertension: Role of angiotensin II and reactive oxygen species
    • Jaimes EA, Zhou MS, Pearse DD, Puzis L, Raij L. Upregulation of cortical COX-2 in salt-sensitive hypertension: role of angiotensin II and reactive oxygen species. Am J Physiol Renal Physiol 2008;294:F385-92
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Jaimes, E.A.1    Zhou, M.S.2    Pearse, D.D.3    Puzis, L.4    Raij, L.5
  • 18
    • 0347334750 scopus 로고    scopus 로고
    • IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
    • Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L. IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J 2003; 17:2115-7
    • (2003) FASEB J , vol.17 , pp. 2115-2117
    • Jung, Y.J.1    Isaacs, J.S.2    Lee, S.3    Trepel, J.4    Neckers, L.5
  • 19
    • 65549096389 scopus 로고    scopus 로고
    • Involvement of NF-kappaB and AP-1 in COX-2 upregulation by human papillomavirus 16 E5 oncoprotein
    • Kim SH, Oh JM, No JH, Bang YJ, Juhnn YS, Song YS. Involvement of NF-kappaB and AP-1 in COX-2 upregulation by human papillomavirus 16 E5 oncoprotein. Carcinogenesis 2009;30:753-7
    • (2009) Carcinogenesis , vol.30 , pp. 753-757
    • Kim, S.H.1    Oh, J.M.2    No, J.H.3    Bang, Y.J.4    Juhnn, Y.S.5    Song, Y.S.6
  • 20
    • 0033805221 scopus 로고    scopus 로고
    • Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes
    • Kontny E, Kurowska M, Szczepanska K, Maslinski W. Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes. J Leukoc Biol 2000;67:249-58
    • (2000) J Leukoc Biol , vol.67 , pp. 249-258
    • Kontny, E.1    Kurowska, M.2    Szczepanska, K.3    Maslinski, W.4
  • 21
    • 0034077529 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade
    • Lasa M, Mahtani KR, Finch A, Brewer G, Saklatvala J, Clark AR. Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade. Mol Cell Biol 2000;20:4265-74
    • (2000) Mol Cell Biol , vol.20 , pp. 4265-4274
    • Lasa, M.1    Mahtani, K.R.2    Finch, A.3    Brewer, G.4    Saklatvala, J.5    Clark, A.R.6
  • 22
    • 65549101773 scopus 로고    scopus 로고
    • Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells
    • Lim JH, Park JW, Choi KS, Park YB, Kwon TK. Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells. Carcinogenesis 2009;30:729-36
    • (2009) Carcinogenesis , vol.30 , pp. 729-736
    • Lim, J.H.1    Park, J.W.2    Choi, K.S.3    Park, Y.B.4    Kwon, T.K.5
  • 24
    • 1642498134 scopus 로고    scopus 로고
    • Aspirin-mediated COX-2 transcript stabilization via sustained p38 activation in human intestinal myofibroblasts
    • Mifflin RC, Saada JI, Di Mari JF, Valentich JD, Adegboyega PA, Powell DW. Aspirin-mediated COX-2 transcript stabilization via sustained p38 activation in human intestinal myofibroblasts. Mol Pharmacol 2004;65:470-8
    • (2004) Mol Pharmacol , vol.65 , pp. 470-478
    • Mifflin, R.C.1    Saada, J.I.2    di Mari, J.F.3    Valentich, J.D.4    Adegboyega, P.A.5    Powell, D.W.6
  • 25
    • 0030985587 scopus 로고    scopus 로고
    • Selective induction of cyclo-oxygenase-2 activity in the permanent human endothelial cell line HUV-EC-C: Biochemical and pharmacological characterization
    • Miralpeix M, Camacho M, Lopez-Belmonte J, Canalias F, Beleta J, Palacios JM, Vila L. Selective induction of cyclo-oxygenase-2 activity in the permanent human endothelial cell line HUV-EC-C: biochemical and pharmacological characterization. Br J Pharmacol 1997; 121:171-80
    • (1997) Br J Pharmacol , vol.121 , pp. 171-180
    • Miralpeix, M.1    Camacho, M.2    Lopez-Belmonte, J.3    Canalias, F.4    Beleta, J.5    Palacios, J.M.6    Vila, L.7
  • 27
    • 0033821771 scopus 로고    scopus 로고
    • Induction of COX-2 and PGE(2) biosynthesis by IL-1beta is mediated by PKC and mitogen-activated protein kinases in murine astrocytes
    • Molina-Holgado E, Ortiz S, Molina-Holgado F, Guaza C. Induction of COX-2 and PGE(2) biosynthesis by IL-1beta is mediated by PKC and mitogen-activated protein kinases in murine astrocytes. Br J Pharmacol 2000;131:152-9
    • (2000) Br J Pharmacol , vol.131 , pp. 152-159
    • Molina-Holgado, E.1    Ortiz, S.2    Molina-Holgado, F.3    Guaza, C.4
  • 28
    • 0036715333 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha (TNF-alpha)-induced prostaglandin E2 release is mediated by the activation of cyclooxygenase-2 (COX-2) transcription via NFkappaB in human gingival fibroblasts
    • Nakao S, Ogtata Y, Shimizu E, Yamazaki M, Furuyama S, Sugiya H. Tumor necrosis factor alpha (TNF-alpha)-induced prostaglandin E2 release is mediated by the activation of cyclooxygenase-2 (COX-2) transcription via NFkappaB in human gingival fibroblasts. Mol Cell Biochem 2002;238:11-8
    • (2002) Mol Cell Biochem , vol.238 , pp. 11-18
    • Nakao, S.1    Ogtata, Y.2    Shimizu, E.3    Yamazaki, M.4    Furuyama, S.5    Sugiya, H.6
  • 29
    • 72049101622 scopus 로고    scopus 로고
    • Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC delta-independent pathway in human colon cancer HT29 cells
    • Park EJ, Lim JH, Nam SI, Park JW, Kwon TK. Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC delta-independent pathway in human colon cancer HT29 cells. Biochimie 2010;92:110-5
    • (2010) Biochimie , vol.92 , pp. 110-115
    • Park, E.J.1    Lim, J.H.2    Nam, S.I.3    Park, J.W.4    Kwon, T.K.5
  • 30
    • 0032515186 scopus 로고    scopus 로고
    • A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA
    • Ridley SH, Dean JL, Sarsfield SJ, Brook M, Clark AR, Saklatvala J. A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA. FEBS Lett 1998;439:75-80
    • (1998) FEBS Lett , vol.439 , pp. 75-80
    • Ridley, S.H.1    Dean, J.L.2    Sarsfield, S.J.3    Brook, M.4    Clark, A.R.5    Saklatvala, J.6
  • 31
    • 27744496768 scopus 로고    scopus 로고
    • The biology of p38 kinase: A central role in inflammation
    • Schieven GL. The biology of p38 kinase: a central role in inflammation. Curr Top Med Chem 2005;5:921-8
    • (2005) Curr Top Med Chem , vol.5 , pp. 921-928
    • Schieven, G.L.1
  • 32
    • 3242771185 scopus 로고    scopus 로고
    • Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: Correlation with suppression of COX-2 synthesis
    • Shishodia S, Koul D, Aggarwal BB. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis. J Immunol 2004;173:2011-22
    • (2004) J Immunol , vol.173 , pp. 2011-2022
    • Shishodia, S.1    Koul, D.2    Aggarwal, B.B.3
  • 33
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 2000;69:145-82
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    Dewitt, D.L.2    Garavito, R.M.3
  • 34
    • 34548511124 scopus 로고    scopus 로고
    • Rottlerin: An inappropriate and ineffective inhibitor of PKCdelta
    • Soltoff SP. Rottlerin: an inappropriate and ineffective inhibitor of PKCdelta. Trends Pharmacol Sci 2007;28:453-8
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 453-458
    • Soltoff, S.P.1
  • 35
    • 48249083788 scopus 로고    scopus 로고
    • Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: The protective role of autophagy in apoptosis
    • Song KS, Kim JS, Yun EJ, Kim YR, Seo KS, Park JH, Jung YJ, Park JI, Kweon GR, Yoon WH, Lim K, Hwang BD. Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis. Autophagy 2008;4:650-8
    • (2008) Autophagy , vol.4 , pp. 650-658
    • Song, K.S.1    Kim, J.S.2    Yun, E.J.3    Kim, Y.R.4    Seo, K.S.5    Park, J.H.6    Jung, Y.J.7    Park, J.I.8    Kweon, G.R.9    Yoon, W.H.10    Lim, K.11    Hwang, B.D.12
  • 36
    • 35648999484 scopus 로고    scopus 로고
    • COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma
    • Song S, Guha S, Liu K, Buttar NS, Bresalier RS. COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma. Gut 2007;56:1512-21
    • (2007) Gut , vol.56 , pp. 1512-1521
    • Song, S.1    Guha, S.2    Liu, K.3    Buttar, N.S.4    Bresalier, R.S.5
  • 38
    • 35748952490 scopus 로고    scopus 로고
    • Sulforaphane suppresses lipopolysaccharide-induced cyclooxygenase-2 (COX-2) expression through the modulation of multiple targets in COX-2 gene promoter
    • Woo KJ, Kwon TK. Sulforaphane suppresses lipopolysaccharide-induced cyclooxygenase-2 (COX-2) expression through the modulation of multiple targets in COX-2 gene promoter. Int Immunopharmacol 2007;7: 1776-83
    • (2007) Int Immunopharmacol , vol.7 , pp. 1776-1783
    • Woo, K.J.1    Kwon, T.K.2


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