Aspirin-Mediated COX-2 Transcript Stabilization via Sustained p38 Activation in Human Intestinal Myofibroblasts

Molecular Pharmacology

Volumn 65, Issue 2, 2004, Pages 470-478

  Mifflin, Randy C ^a   Saada, Jamal I ^a   Di Mari, John F ^a   Valentich, John D ^a   Adegboyega, Patrick A ^a   Powell, Don W ^b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLSALICYLIC ACID; CYCLOOXYGENASE 2; GENE PRODUCT; GRO ALPHA PROTEIN; INDOMETACIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; ISOENZYME; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MESALAZINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; RECOMBINANT INTERLEUKIN 1; RECOMBINANT INTERLEUKIN 1ALPHA; SALICYLATE SODIUM; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANALGESIA; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CONTROLLED STUDY; CYTOLOGY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME STABILITY; ENZYMOLOGY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HALF LIFE TIME; HUMAN; HUMAN CELL; INHIBITION KINETICS; INTESTINE; INTESTINE CELL; METABOLISM; MYOFIBROBLAST; PHYSIOLOGY; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN RNA BINDING; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA STABILITY; STEADY STATE; TRANSCRIPTION REGULATION;

ASPIRIN; CELLS, CULTURED; CYCLOOXYGENASE 2; ENZYME ACTIVATION; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTESTINES; ISOENZYMES; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA STABILITY; TRANSCRIPTION, GENETIC;

EID: 1642498134     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.65.2.470     Document Type: Article

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