Knockdown of the β 1 integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis

International Journal of Cancer

Volumn 129, Issue 12, 2011, Pages 2905-2915

  Grzesiak, John J ^a,b   Cao, Hop S Tran ^c   Burton, Douglas W ^a,d   Kaushal, Sharmeela ^b   Vargas, Fabian ^a   Clopton, Paul ^a   Snyder, Cynthia S ^b   Deftos, Leonard J ^a,d   Hoffman, Robert M ^c,e   Bouvet, Michael ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e ANTICANCER INC   (United States)

Author keywords

extracellular matrix; integrins; orthotopic mouse models; pancreatic cancer; RNA interference

Indexed keywords

ALPHA2 INTEGRIN; ALPHA3 INTEGRIN; BETA1 INTEGRIN; BETA5 INTEGRIN; COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRONECTIN; LAMININ; SCLEROPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DENSITOMETRY; IN VITRO STUDY; IN VIVO STUDY; METASTASIS POTENTIAL; MOLECULAR CLONING; MOUSE; NONHUMAN; PANCREAS CANCER; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR GROWTH; TUMOR MICROENVIRONMENT; ANIMAL; CELL MOTION; DISEASE COURSE; GENE SILENCING; GENETICS; HUMAN; METABOLISM; METASTASIS; NUDE MOUSE; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD29; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DISEASE PROGRESSION; EXTRACELLULAR MATRIX PROTEINS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MICE, NUDE; NEOPLASM METASTASIS; PANCREATIC NEOPLASMS;

EID: 84855165949     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25942     Document Type: Article

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