Expression and assay of HECT domain ligases

Methods in Enzymology

Volumn 398, Issue , 2005, Pages 112-125

  Beaudenon, Sylvie ^a   Dastur, Anahita ^a   Huibregtse, Jon M ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

E6 ASSOCIATED PROTEIN; PROTEIN; PROTEIN RSP5P; THIOESTER; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; UBIQUITINATION;

EID: 27644522319     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(05)98011-7     Document Type: Review

References (48)

1. + channel by Nedd4 in Liddle's syndrome J. Clin. Invest. 103 1999 667 673
2. Albrecht U., Sutcliffe J.S., Cattanach B.M., Beechey C.V., Armstrong D., Eichele G., and Beaudet A.L. Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons Nature Genet. 17 1997 75 78
3. Arora K., and Warrior R. A new Smurf in the village Dev. Cell 1 2001 441 442
4. de la Fuente N., Maldonado A.M., and Portillo F. Glucose activation of the yeast plasma membrane H+-ATPase requires the ubiquitin-proteasome proteolytic pathway FEBS Lett. 411 1997 308 312
5. Dunn R., and Hicke L. Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosis Mol. Biol. Cell 12 2001 421 435
6. Fang P., Lev-Lehman E., Tsai T.F., Matsuura T., Benton C.S., Sutcliffe J.S., Christian S.L., Kubota T., Halley D.J., Meijers-Heijboer H., Langlois S., Graham J.M. Jr., Beuten J., Willems P.J., Ledbetter D.H., and Beaudet A.L. The spectrum of mutations in UBE3A causing Angelman syndrome Hum. Mol. Genet. 8 1999 129 135
7. Gitan R.S., and Eide D.J. Zinc-regulated ubiquitin conjugation signals endocytosis of the yeast ZRT1 zinc transporter Biochem. J. 346 Pt 2 2000 329 336
8. + channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome J. Biol. Chem. 273 1998 30012 30017
9. Harty R.N., Brown M.E., Wang G., Huibregtse J., and Hayes F.P. A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: Implications for filovirus budding Proc. Natl. Acad. Sci. USA 97 2000 13871 13876
10. Hein C., Springael J.Y., Volland C., Haguenauer-Tsapis R., and Andre B. NPl1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase Mol. Microbiol. 18 1995 77 87
11. Hoppe T., Matuschewski K., Rape M., Schlenker S., Ulrich H.D., and Jentsch S. Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing Cell 102 2000 577 586
12. Huang L., Kinnucan E., Wang G., Beaudenon S., Howley P.M., Huibregtse J.M., and Pavletich N.P. Structure of an E6AP-UbcH7 complex: Insights into ubiquitination by the E2-E3 enzyme cascade Science 286 1999 1321 1326
13. Huibregtse J.M., Scheffner M., Beaudenon S., and Howley P.M. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase Proc. Natl. Acad. Sci. USA 92 1995 2563 2567
14. Huibregtse J.M., Scheffner M., and Howley P.M. A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18 EMBO J. 10 1991 4129 4135
15. Huibregtse J.M., Scheffner M., and Howley P.M. Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53 Mol. Cell. Biol. 13 1993 775 784
16. Huibregtse J.M., Scheffner M., and Howley P.M. Localization of the E6-AP regions that direct human papillomavirus e6 binding, association with p53, and ubiquitination of associated proteins Mol. Cell. Biol. 13 1993 4918 4927
17. Huibregtse J.M., Yang J.C., and Beaudenon S.L. The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase Proc. Natl. Acad. Sci. USA 94 1997 3656 3661
18. Ingham R.J., Gish G., and Pawson T. The Nedd4 family of E3 ubiquitin ligases: Functional diversity within a common modular architecture Oncogene 23 2004 1972 1984
19. Jiang Y., Lev-Lehman E., Bressler J., Tsai T.F., and Beaudet A.L. Genetics of Angelman syndrome Am. J. Hum. Genet. 65 1999 1 6
20. Kikonyogo A., Bouamr F., Vana M.L., Xiang Y., Aiyar A., Carter C., and Leis J. Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells Proc. Natl. Acad. Sci. USA 98 2001 11199 11204
21. King R.W., Lustig K.D., Stukenberg P.T., McGarry T.J., and Kirschner M.W. Expression cloning in the test tube Science 277 1997 973 974
22. Kishino T., Lalande M., and Wagstaff J. UBE3A/E6-AP mutations cause Angelman syndrome Nature Genet. 15 1997 70 73
23. Kumar S., Kao W.H., and Howley P.M. Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity J. Biol. Chem. 272 1997 13548 13554
24. Kumar S., Talis A.L., and Howley P.M. Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination J. Biol. Chem. 274 1999 18785 18792
25. Lin X., Liang M., and Feng X.H. Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling J. Biol. Chem. 275 2000 36818 36822
26. Lustig K.D., Stukenberg P.T., McGarry T.J., King R.W., Cryns V.L., Mead P.E., Zon L.I., Yuan J., and Kirschner M.W. Small pool expression screening: Identification of genes involved in cell cycle control, apoptosis, and early development Methods Enzymol. 283 1997 83 99
27. McGarry T.J., and Kirschner M.W. Geminin, an inhibitor of DNA replication, is degraded during mitosis Cell 93 1998 1043 1053
28. Mitsui K., Nakanishi M., Ohtsuka S., Norwood T.H., Okabayashi K., Miyamoto C., Tanaka K., Yoshimura A., and Ohtsubo M. A novel human gene encoding HECT domain and RCC1-like repeats interacts with cyclins and is potentially regulated by the tumor suppressor proteins Biochem. Biophys. Res. Commun. 266 1999 115 122
29. Nakagawa S., and Huibregtse J.M. Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase Mol. Cell. Biol. 20 2000 8244 8253
30. Nuber U., and Scheffner M. Identification of determinants in E2 ubiquitin-conjugating enzymes required for hect E3 ubiquitin-protein ligase interaction J. Biol. Chem. 274 1999 7576 7582
31. Pickart C.M. Mechanisms underlying ubiquitination Annu. Rev. Biochem. 70 2001 503 533
32. Puig O., Caspary F., Rigaut G., Rutz B., Bouveret E., Bragado-Nilsson E., Wilm M., and Seraphin B. The tandem affinity purification (TAP) method: A general procedure of protein complex purification Methods 24 2001 218 229
33. Sakurai A., Yasuda J., Takano H., Tanaka Y., Hatakeyama M., and Shida H. Regulation of human T-cell leukemia virus type 1 (HTLV-1) budding by ubiquitin ligase Nedd4 Microbes Infect. 6 2004 150 156
34. Salvat C., Wang G., Dastur A., Lyon N., and Huibregtse J.M. The -4 phenylalanine is required for substrate ubiquitination catalyzed by HECT ubiquitin ligases J. Biol. Chem. 279 2004 18935 18943
35. Scheffner M. Ubiquitin, E6-AP, and their role in p53 inactivation Pharmacol. Ther. 78 1998 129 139
36. Scheffner M., Huibregtse J.M., Vierstra R.D., and Howley P.M. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 Cell 75 1993 495 505
37. Scheffner M., Nuber U., and Huibregtse J.M. Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade Nature 373 1995 81 83
38. Scheffner M., Werness B.A., Huibregtse J.M., Levine A.J., and Howley P.M. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 Cell 63 1990 1129 1136
39. Schwarz S.E., Rosa J.L., and Scheffner M. Characterization of human hect domain family members and their interaction with UbcH5 and UbcH7 J. Biol. Chem. 273 1998 12148 12154
40. Springael J.Y., and Andre B. Nitrogen-regulated ubiquitination of the gap1 permease of Saccharomyces cerevisiae Mol. Biol. Cell 9 1998 1253 1263
41. + channel deleted in Liddle's syndrome EMBO J. 15 1996 2371 2380
42. Suzuki C., Murakami G., Fukuchi M., Shimanuki T., Shikauchi Y., Imamura T., and Miyazono K. Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane J. Biol. Chem. 277 2002 39919 39925
43. Traweger A., Fang D., Liu Y.C., Stelzhammer W., Krizbai I.A., Fresser F., Bauer H.C., and Bauer H. The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase itch J. Biol. Chem. 277 2002 10201 10208
44. Verdecia M.A., Joazeiro C.A., Wells N.J., Ferrer J.L., Bowman M.E., Hunter T., and Noel J.P. Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase Mol. Cell 11 2003 249 259
45. Wang G., Yang J., and Huibregtse J.M. Functional domains of the Rsp5 ubiquitin-protein ligase Mol. Cell. Biol. 19 1999 342 352
46. Yasuda J., Nakao M., Kawaoka Y., and Shida H. Nedd4 regulates egress of Ebola virus-like particles from host cells J. Virol. 77 2003 9987 9992
47. Zhang Y., Wang H.R., and Wrana J.L. Smurf1: A link between cell polarity and ubiquitination Cell Cycle 3 2004 391 392
48. Zhao C., Beaudenon S.L., Kelley M.L., Waddell M.B., Yuan W., Schulman B.A., Huibregtse J.M., and Krug R.M. The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein Proc. Natl. Acad. Sci. USA 101 2004 7578 7582