Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells

Cardiovascular Research

Volumn 80, Issue 2, 2008, Pages 299-308

  Meng, Dan ^a   Lv, Dan Dan ^a   Fang, Jing ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Insulin like growth factor I; Nox4; Rac1; Reactive oxygen species; Vascular smooth muscle cells

Indexed keywords

CYCLOHEXIMIDE; DACTINOMYCIN; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CELL MIGRATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; IMMUNOBLOTTING; MALE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; INSULIN-LIKE GROWTH FACTOR I; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TIME FACTORS;

EID: 54149115156     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn173     Document Type: Article

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