-
1
-
-
58849162826
-
Acute exacerbations of asthma: Epidemiology, biology and the exacerbation-prone phenotype
-
R.H. Dougherty, and J.V. Fahy Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype Clin Exp Allergy 39 2009 193 202
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 193-202
-
-
Dougherty, R.H.1
Fahy, J.V.2
-
2
-
-
0027525233
-
Respiratory viruses and exacerbations of asthma in adults
-
K.G. Nicholson, J. Kent, and D.C. Ireland Respiratory viruses and exacerbations of asthma in adults BMJ 307 1993 982 986
-
(1993)
BMJ
, vol.307
, pp. 982-986
-
-
Nicholson, K.G.1
Kent, J.2
Ireland, D.C.3
-
3
-
-
0028990124
-
Community study of role of viral infections in exacerbations of asthma in 9-11 year old children
-
S.L. Johnston, P.K. Pattemore, G. Sanderson, S. Smith, F. Lampe, and L. Josephs Community study of role of viral infections in exacerbations of asthma in 9-11 year old children BMJ 310 1995 1225 1229
-
(1995)
BMJ
, vol.310
, pp. 1225-1229
-
-
Johnston, S.L.1
Pattemore, P.K.2
Sanderson, G.3
Smith, S.4
Lampe, F.5
Josephs, L.6
-
4
-
-
55549094831
-
Gene expression profiles during in vivo human rhinovirus infection: Insights into the host response
-
D. Proud, R.B. Turner, B. Winther, S. Wiehler, J.P. Tiesman, and T.D. Reichling Gene expression profiles during in vivo human rhinovirus infection: insights into the host response Am J Respir Crit Care Med 178 2008 962 968
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 962-968
-
-
Proud, D.1
Turner, R.B.2
Winther, B.3
Wiehler, S.4
Tiesman, J.P.5
Reichling, T.D.6
-
5
-
-
69949148793
-
Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans
-
A.K. Zaas, M. Chen, J. Varkey, T. Veldman, A.O. Hero 3rd, and J. Lucas Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans Cell Host Microbe 6 2009 207 217
-
(2009)
Cell Host Microbe
, vol.6
, pp. 207-217
-
-
Zaas, A.K.1
Chen, M.2
Varkey, J.3
Veldman, T.4
Hero III, A.O.5
Lucas, J.6
-
6
-
-
13444280369
-
Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma
-
J.R. Guajardo, K.W. Schleifer, M.O. Daines, R.M. Ruddy, B.J. Aronow, and M. Wills-Karp Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma J Allergy Clin Immunol 115 2005 243 251
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 243-251
-
-
Guajardo, J.R.1
Schleifer, K.W.2
Daines, M.O.3
Ruddy, R.M.4
Aronow, B.J.5
Wills-Karp, M.6
-
7
-
-
70149089062
-
Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children
-
L.S. Subrata, J. Bizzintino, E. Mamessier, A. Bosco, K.L. McKenna, and M.E. Wikstrom Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children J Immunol 183 2009 2793 2800
-
(2009)
J Immunol
, vol.183
, pp. 2793-2800
-
-
Subrata, L.S.1
Bizzintino, J.2
Mamessier, E.3
Bosco, A.4
McKenna, K.L.5
Wikstrom, M.E.6
-
8
-
-
77249119309
-
Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma
-
Y.A. Bochkov, K.M. Hanson, S. Keles, R.A. Brockman-Schneider, N.N. Jarjour, and J.E. Gern Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma Mucosal Immunol 3 2010 69 80
-
(2010)
Mucosal Immunol
, vol.3
, pp. 69-80
-
-
Bochkov, Y.A.1
Hanson, K.M.2
Keles, S.3
Brockman-Schneider, R.A.4
Jarjour, N.N.5
Gern, J.E.6
-
9
-
-
77953787260
-
Decreased activation of inflammatory networks during acute asthma exacerbations is associated with chronic airflow obstruction
-
A. Bosco, S. Ehteshami, D.A. Stern, and F.D. Martinez Decreased activation of inflammatory networks during acute asthma exacerbations is associated with chronic airflow obstruction Mucosal Immunol 3 2010 399 409
-
(2010)
Mucosal Immunol
, vol.3
, pp. 399-409
-
-
Bosco, A.1
Ehteshami, S.2
Stern, D.A.3
Martinez, F.D.4
-
10
-
-
0742305866
-
Network biology: Understanding the cell's functional organization
-
A.L. Barabasi, and Z.N. Oltvai Network biology: understanding the cell's functional organization Nat Rev Genet 5 2004 101 113
-
(2004)
Nat Rev Genet
, vol.5
, pp. 101-113
-
-
Barabasi, A.L.1
Oltvai, Z.N.2
-
12
-
-
0037199968
-
Hierarchical organization of modularity in metabolic networks
-
E. Ravasz, A.L. Somera, D.A. Mongru, Z.N. Oltvai, and A.L. Barabasi Hierarchical organization of modularity in metabolic networks Science 297 2002 1551 1555
-
(2002)
Science
, vol.297
, pp. 1551-1555
-
-
Ravasz, E.1
Somera, A.L.2
Mongru, D.A.3
Oltvai, Z.N.4
Barabasi, A.L.5
-
13
-
-
70249134919
-
Molecular networks as sensors and drivers of common human diseases
-
E.E. Schadt Molecular networks as sensors and drivers of common human diseases Nature 461 2009 218 223
-
(2009)
Nature
, vol.461
, pp. 218-223
-
-
Schadt, E.E.1
-
14
-
-
60549111634
-
WGCNA: An R package for weighted correlation network analysis
-
P. Langfelder, and S. Horvath WGCNA: an R package for weighted correlation network analysis BMC Bioinformatics 9 2008 559
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 559
-
-
Langfelder, P.1
Horvath, S.2
-
15
-
-
67649805319
-
An official American Thoracic Society/European Respiratory Society statement: Asthma control and exacerbations: Standardizing endpoints for clinical asthma trials and clinical practice
-
H.K. Reddel, D.R. Taylor, E.D. Bateman, L.P. Boulet, H.A. Boushey, and W.W. Busse An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice Am J Respir Crit Care Med 180 2009 59 99
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 59-99
-
-
Reddel, H.K.1
Taylor, D.R.2
Bateman, E.D.3
Boulet, L.P.4
Boushey, H.A.5
Busse, W.W.6
-
16
-
-
77649252969
-
A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease
-
A. Bosco, K.L. McKenna, M.J. Firth, P.D. Sly, and P.G. Holt A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease J Immunol 182 2009 6011 6021
-
(2009)
J Immunol
, vol.182
, pp. 6011-6021
-
-
Bosco, A.1
McKenna, K.L.2
Firth, M.J.3
Sly, P.D.4
Holt, P.G.5
-
17
-
-
4544341015
-
Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
-
Article3
-
G.K. Smyth Linear models and empirical Bayes methods for assessing differential expression in microarray experiments Stat Appl Genet Mol Biol 3 2004 Article3
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
-
-
Smyth, G.K.1
-
18
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
W. Huang da, B.T. Sherman, and R.A. Lempicki Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat Protocol 4 2009 44 57
-
(2009)
Nat Protocol
, vol.4
, pp. 44-57
-
-
Huang Da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
19
-
-
70349882120
-
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
-
I. Amit, M. Garber, N. Chevrier, A.P. Leite, Y. Donner, and T. Eisenhaure Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses Science 326 2009 257 263
-
(2009)
Science
, vol.326
, pp. 257-263
-
-
Amit, I.1
Garber, M.2
Chevrier, N.3
Leite, A.P.4
Donner, Y.5
Eisenhaure, T.6
-
20
-
-
35348960378
-
STAT3 mutations in the hyper-IgE syndrome
-
S.M. Holland, F.R. DeLeo, H.Z. Elloumi, A.P. Hsu, G. Uzel, and N. Brodsky STAT3 mutations in the hyper-IgE syndrome N Engl J Med 357 2007 1608 1619
-
(2007)
N Engl J Med
, vol.357
, pp. 1608-1619
-
-
Holland, S.M.1
Deleo, F.R.2
Elloumi, H.Z.3
Hsu, A.P.4
Uzel, G.5
Brodsky, N.6
-
21
-
-
33745308594
-
Stat3 is required for cytoprotection of the respiratory epithelium during adenoviral infection
-
Y. Matsuzaki, Y. Xu, M. Ikegami, V. Besnard, K.S. Park, and W.M. Hull Stat3 is required for cytoprotection of the respiratory epithelium during adenoviral infection J Immunol 177 2006 527 537
-
(2006)
J Immunol
, vol.177
, pp. 527-537
-
-
Matsuzaki, Y.1
Xu, Y.2
Ikegami, M.3
Besnard, V.4
Park, K.S.5
Hull, W.M.6
-
22
-
-
0032489828
-
Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50
-
H. Ishikawa, E. Claudio, D. Dambach, C. Raventos-Suarez, C. Ryan, and R. Bravo Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50 J Exp Med 187 1998 985 996
-
(1998)
J Exp Med
, vol.187
, pp. 985-996
-
-
Ishikawa, H.1
Claudio, E.2
Dambach, D.3
Raventos-Suarez, C.4
Ryan, C.5
Bravo, R.6
-
23
-
-
79151473780
-
NF-kappaB and STAT3 signaling hubs for lung innate immunity
-
L.J. Quinton, and J.P. Mizgerd NF-kappaB and STAT3 signaling hubs for lung innate immunity Cell Tissue Res 343 2011 153 165
-
(2011)
Cell Tissue Res
, vol.343
, pp. 153-165
-
-
Quinton, L.J.1
Mizgerd, J.P.2
-
24
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
F. Martinon, X. Chen, A.H. Lee, and L.H. Glimcher TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages Nat Immunol 11 2010 411 418
-
(2010)
Nat Immunol
, vol.11
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.H.3
Glimcher, L.H.4
-
25
-
-
79953034321
-
ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells
-
F. Hu, X. Yu, H. Wang, D. Zuo, C. Guo, and H. Yi ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells Eur J Immunol 41 2011 1086 1097
-
(2011)
Eur J Immunol
, vol.41
, pp. 1086-1097
-
-
Hu, F.1
Yu, X.2
Wang, H.3
Zuo, D.4
Guo, C.5
Yi, H.6
-
26
-
-
34548129605
-
Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response
-
J. Hiscott Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response Cytokine Growth Factor Rev 18 2007 483 490
-
(2007)
Cytokine Growth Factor Rev
, vol.18
, pp. 483-490
-
-
Hiscott, J.1
-
27
-
-
77957228318
-
Central roles of NLRs and inflammasomes in viral infection
-
T.D. Kanneganti Central roles of NLRs and inflammasomes in viral infection Nat Rev Immunol 10 2010 688 698
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 688-698
-
-
Kanneganti, T.D.1
-
28
-
-
33646377870
-
Interferon signalling network in innate defence
-
A. Takaoka, and H. Yanai Interferon signalling network in innate defence Cell Microbiol 8 2006 907 922
-
(2006)
Cell Microbiol
, vol.8
, pp. 907-922
-
-
Takaoka, A.1
Yanai, H.2
-
29
-
-
29244442569
-
Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type i interferon activity
-
J.E. Fenner, R. Starr, A.L. Cornish, J.G. Zhang, D. Metcalf, and R.D. Schreiber Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity Nat Immunol 7 2006 33 39
-
(2006)
Nat Immunol
, vol.7
, pp. 33-39
-
-
Fenner, J.E.1
Starr, R.2
Cornish, A.L.3
Zhang, J.G.4
Metcalf, D.5
Schreiber, R.D.6
-
30
-
-
70349251863
-
Interleukin-27 inhibition of HIV-1 involves an intermediate induction of type i interferon
-
T. Greenwell-Wild, N. Vazquez, W. Jin, Z. Rangel, P.J. Munson, and S.M. Wahl Interleukin-27 inhibition of HIV-1 involves an intermediate induction of type I interferon Blood 114 2009 1864 1874
-
(2009)
Blood
, vol.114
, pp. 1864-1874
-
-
Greenwell-Wild, T.1
Vazquez, N.2
Jin, W.3
Rangel, Z.4
Munson, P.J.5
Wahl, S.M.6
-
31
-
-
33847645819
-
Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression
-
H. Yanai, H.M. Chen, T. Inuzuka, S. Kondo, T.W. Mak, and A. Takaoka Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression Proc Natl Acad Sci U S A 104 2007 3402 3407
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3402-3407
-
-
Yanai, H.1
Chen, H.M.2
Inuzuka, T.3
Kondo, S.4
Mak, T.W.5
Takaoka, A.6
-
32
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
K. Honda, H. Yanai, H. Negishi, M. Asagiri, M. Sato, and T. Mizutani IRF-7 is the master regulator of type-I interferon-dependent immune responses Nature 434 2005 772 777
-
(2005)
Nature
, vol.434
, pp. 772-777
-
-
Honda, K.1
Yanai, H.2
Negishi, H.3
Asagiri, M.4
Sato, M.5
Mizutani, T.6
-
33
-
-
63449127873
-
Managing childhood asthma: Challenge of preventing exacerbations
-
F.D. Martinez Managing childhood asthma: challenge of preventing exacerbations Pediatrics 123 suppl 3 2009 S146 S150
-
(2009)
Pediatrics
, vol.123
, Issue.SUPPL.3
-
-
Martinez, F.D.1
-
34
-
-
27844446240
-
Embracing complexity, inching closer to reality
-
pe40
-
E.E. Schadt, A. Sachs, and S. Friend Embracing complexity, inching closer to reality Sci STKE 2005 2005 pe40
-
(2005)
Sci STKE
, vol.2005
-
-
Schadt, E.E.1
Sachs, A.2
Friend, S.3
-
36
-
-
54249155522
-
Network pharmacology: The next paradigm in drug discovery
-
A.L. Hopkins Network pharmacology: the next paradigm in drug discovery Nat Chem Biol 4 2008 682 690
-
(2008)
Nat Chem Biol
, vol.4
, pp. 682-690
-
-
Hopkins, A.L.1
-
37
-
-
27144509163
-
A network-based analysis of systemic inflammation in humans
-
S.E. Calvano, W. Xiao, D.R. Richards, R.M. Felciano, H.V. Baker, and R.J. Cho A network-based analysis of systemic inflammation in humans Nature 437 2005 1032 1037
-
(2005)
Nature
, vol.437
, pp. 1032-1037
-
-
Calvano, S.E.1
Xiao, W.2
Richards, D.R.3
Felciano, R.M.4
Baker, H.V.5
Cho, R.J.6
-
38
-
-
46749152178
-
A modular analysis framework for blood genomics studies: Application to systemic lupus erythematosus
-
D. Chaussabel, C. Quinn, J. Shen, P. Patel, C. Glaser, and N. Baldwin A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus Immunity 29 2008 150 164
-
(2008)
Immunity
, vol.29
, pp. 150-164
-
-
Chaussabel, D.1
Quinn, C.2
Shen, J.3
Patel, P.4
Glaser, C.5
Baldwin, N.6
-
39
-
-
62649129291
-
A module-based analytical strategy to identify novel disease-associated genes shows an inhibitory role for interleukin 7 receptor in allergic inflammation
-
R. Mobini, B.A. Andersson, J. Erjefalt, M. Hahn-Zoric, M.A. Langston, and A.D. Perkins A module-based analytical strategy to identify novel disease-associated genes shows an inhibitory role for interleukin 7 receptor in allergic inflammation BMC Syst Biol 3 2009 19
-
(2009)
BMC Syst Biol
, vol.3
, pp. 19
-
-
Mobini, R.1
Andersson, B.A.2
Erjefalt, J.3
Hahn-Zoric, M.4
Langston, M.A.5
Perkins, A.D.6
-
40
-
-
79952659846
-
Boosting signal-to-noise in complex biology: Prior knowledge is power
-
T. Ideker, J. Dutkowski, and L. Hood Boosting signal-to-noise in complex biology: prior knowledge is power Cell 144 2011 860 863
-
(2011)
Cell
, vol.144
, pp. 860-863
-
-
Ideker, T.1
Dutkowski, J.2
Hood, L.3
-
41
-
-
0034721164
-
Error and attack tolerance of complex networks
-
R. Albert, H. Jeong, and A.L. Barabasi Error and attack tolerance of complex networks Nature 406 2000 378 382
-
(2000)
Nature
, vol.406
, pp. 378-382
-
-
Albert, R.1
Jeong, H.2
Barabasi, A.L.3
-
42
-
-
48749104048
-
Innate immune modulation by RNA viruses: Emerging insights from functional genomics
-
M.G. Katze, J.L. Fornek, R.E. Palermo, K.A. Walters, and M.J. Korth Innate immune modulation by RNA viruses: emerging insights from functional genomics Nat Rev Immunol 8 2008 644 654
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 644-654
-
-
Katze, M.G.1
Fornek, J.L.2
Palermo, R.E.3
Walters, K.A.4
Korth, M.J.5
-
43
-
-
79955542915
-
A diverse range of gene products are effectors of the type i interferon antiviral response
-
J.W. Schoggins, S.J. Wilson, M. Panis, M.Y. Murphy, C.T. Jones, and P. Bieniasz A diverse range of gene products are effectors of the type I interferon antiviral response Nature 472 2011 481 485
-
(2011)
Nature
, vol.472
, pp. 481-485
-
-
Schoggins, J.W.1
Wilson, S.J.2
Panis, M.3
Murphy, M.Y.4
Jones, C.T.5
Bieniasz, P.6
-
44
-
-
32044440119
-
Rhinovirus induces airway epithelial gene expression through double-stranded RNA and IFN-dependent pathways
-
Y. Chen, E. Hamati, P.K. Lee, W.M. Lee, S. Wachi, and D. Schnurr Rhinovirus induces airway epithelial gene expression through double-stranded RNA and IFN-dependent pathways Am J Respir Cell Mol Biol 34 2006 192 203
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 192-203
-
-
Chen, Y.1
Hamati, E.2
Lee, P.K.3
Lee, W.M.4
Wachi, S.5
Schnurr, D.6
-
45
-
-
73349104638
-
Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses
-
Q. Wang, D.R. Nagarkar, E.R. Bowman, D. Schneider, B. Gosangi, and J. Lei Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses J Immunol 183 2009 6989 6997
-
(2009)
J Immunol
, vol.183
, pp. 6989-6997
-
-
Wang, Q.1
Nagarkar, D.R.2
Bowman, E.R.3
Schneider, D.4
Gosangi, B.5
Lei, J.6
-
46
-
-
33748475531
-
Type i interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
-
K. Honda, A. Takaoka, and T. Taniguchi Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors Immunity 25 2006 349 360
-
(2006)
Immunity
, vol.25
, pp. 349-360
-
-
Honda, K.1
Takaoka, A.2
Taniguchi, T.3
|