Detection of a minor amorphous phase in crystalline etoricoxib by dynamic mechanical analysis: Comparison with raman spectroscopy and modulated differential scanning calorimetry

Journal of Pharmaceutical Sciences

Volumn 101, Issue 2, 2012, Pages 558-565

  Clas, Sophie Dorothee ^a,b   Lalonde, Karine ^a   Khougaz, Karine ^a   Dalton, Chad R ^a,b   Bilbeisi, Rana ^a  

^a Merck Canada   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Amorphous; Crystalline; DMA; Dynamic mechanical analysis; Etoricoxib; Glass transition; Limit of detection; MDSC; Modulated differential scanning calorimetry; Raman spectroscopy; Stainless steel powder pockets; Thermal analysis

Indexed keywords

CRYSTALLIN; ETORICOXIB;

ARTICLE; CALIBRATION; DIFFERENTIAL SCANNING CALORIMETRY; INTERMETHOD COMPARISON; LIMIT OF DETECTION; LIMIT OF QUANTITATION; RAMAN SPECTROMETRY;

EID: 84455188930     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22774     Document Type: Article

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