Quantification of process induced disorder in milled samples using different analytical techniques

Pharmaceutics

Volumn 2, Issue 1, 2010, Pages 30-49

  Zimper, Ulrike ^a   Aaltonen, Jaakko ^a,b   McGoverin, Cushla M ^a   Gordon, Keith C ^a   Krauel Goellner, Karen ^c   Rades, Thomas ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

Amorphous; Ball milling; DSC; Indomethacin simvastatin; Multivariate analysis; Partial least squares regression (PLS); Principal component analysis (PCA); Process induced disorder; Raman spectroscopy; XRPD

Indexed keywords

INDOMETACIN; SIMVASTATIN;

ARTICLE; CALIBRATION; CRYOCOAGULATION; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DESIGN; DRUG MIXTURE; DRUG STABILITY; DRUG STRUCTURE; GLASS TRANSITION TEMPERATURE; HEAT TOLERANCE; PRINCIPAL COMPONENT ANALYSIS; RAMAN SPECTROMETRY; TABLET FORMULATION; THERMAL ANALYSIS; X RAY POWDER DIFFRACTION;

EID: 79952078556     PISSN: None     EISSN: 19994923     Source Type: Journal    
DOI: 10.3390/pharmaceutics2010030     Document Type: Article

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