메뉴 건너뛰기




Volumn 40, Issue 1, 2012, Pages 209-216

Clinical significance of UNC5B expression in colorectal cancer

Author keywords

Colorectal cancer; Methylation; UNC5B

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENTARY DNA; MESSENGER RNA; PROTEIN UNC5B; UNCLASSIFIED DRUG;

EID: 84455163052     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1201     Document Type: Article
Times cited : (49)

References (37)
  • 1
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer pathogenesis
    • Grady WM and Carethers JM: Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 135: 1079-1099, 2008.
    • (2008) Gastroenterology , vol.135 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 2
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • DOI 10.1038/5947
    • Jones PA and Laird PW: Cancer epigenetics comes of age. Nat Genet 21: 163-167, 1999. (Pubitemid 29070360)
    • (1999) Nature Genetics , vol.21 , Issue.2 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 3
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histonemodification maps
    • Esteller M: Cancer epigenomics: DNA methylomes and histonemodification maps. Nat Rev Genet 8: 286-298, 2007.
    • (2007) Nat Rev Genet , vol.8 , pp. 286-298
    • Esteller, M.1
  • 4
    • 33846008439 scopus 로고    scopus 로고
    • Colorectal cancer: A model for epigenetic tumorigenesis
    • DOI 10.1136/gut.2005.088799
    • Wong JJ, Hawkins NJ and Ward RL: Colorectal cancer: a model for epigenetic tumorigenesis. Gut 56: 140-148, 2007. (Pubitemid 46044900)
    • (2007) Gut , vol.56 , Issue.1 , pp. 140-148
    • Wong, J.J.L.1    Hawkins, N.J.2    Ward, R.L.3
  • 5
    • 7644228433 scopus 로고    scopus 로고
    • CpG island methylation in gastroenterologic neoplasia: A maturing field
    • DOI 10.1053/j.gastro.2004.09.007, PII S0016508504015768
    • Rashid A and Issa JP: CpG island methylation in gastroenterologic neoplasia: a maturing field. Gastroenterology 127: 1578-1588, 2004. (Pubitemid 39457781)
    • (2004) Gastroenterology , vol.127 , Issue.5 , pp. 1578-1588
    • Rashid, A.1    Issa, J.P.J.2
  • 6
    • 10344260184 scopus 로고    scopus 로고
    • CpG island methylator phenotype in cancer
    • Issa JP: CpG island methylator phenotype in cancer. Nat Rev Cancer 4: 988-993, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 8
    • 0033928171 scopus 로고    scopus 로고
    • The epigenetics of colorectal cancer
    • Issa JP: The epigenetics of colorectal cancer. Ann N Y Acad Sci 910: 140-153, 2000.
    • (2000) Ann N Y Acad Sci , vol.910 , pp. 140-153
    • Issa, J.P.1
  • 9
    • 0036895068 scopus 로고    scopus 로고
    • Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands
    • DOI 10.1136/gut.51.6.797
    • van Rijnsoever M, Grieu F, Elsaleh H, Joseph D and Iacopetta B: Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands. Gut 51: 797-802, 2002. (Pubitemid 35408598)
    • (2002) Gut , vol.51 , Issue.6 , pp. 797-802
    • Van Rijnsoever, M.1    Grieu, F.2    Elsaleh, H.3    Joseph, D.4    Iacopetta, B.5
  • 11
    • 0031017268 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
    • K ane MF, Loda M, Gaida GM, et al.: Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 57: 808-811, 1997.
    • (1997) Cancer Res , vol.57 , pp. 808-811
    • Kane, M.F.1    Loda, M.2    Gaida, G.M.3
  • 13
    • 23844517119 scopus 로고    scopus 로고
    • Diagnostic and therapeutic applications of epigenetics
    • DOI 10.1093/jjco/hyi088
    • Miyamoto K and Ushijima T: Diagnostic and therapeutic applications of epigenetics. Jpn J Clin Oncol 35: 293-301, 2005. (Pubitemid 41444276)
    • (2005) Japanese Journal of Clinical Oncology , vol.35 , Issue.6 , pp. 293-301
    • Miyamoto, K.1    Ushijima, T.2
  • 14
    • 0036735638 scopus 로고    scopus 로고
    • DNA methylation: An epigenetic pathway to cancer and a promising target for anticancer therapy
    • Worm J and Guldberg P: DNA methylation: an epigenetic pathway to cancer and a promising target for anticancer therapy. J Oral Pathol Med 31: 443-449, 2002.
    • (2002) J Oral Pathol Med , vol.31 , pp. 443-449
    • Worm, J.1    Guldberg, P.2
  • 15
    • 35348832560 scopus 로고    scopus 로고
    • The synergistic effect of 5-aza-2′-deoxycytidine and 5-fluorouracil on drug-resistant tumors
    • Morita S, Iida S, Kato K, Takagi Y, Uetake H and Sugihara K: The synergistic effect of 5-aza-2′-deoxycytidine and 5-fluorouracil on drug-resistant tumors. Oncology 71: 437-445, 2006.
    • (2006) Oncology , vol.71 , pp. 437-445
    • Morita, S.1    Iida, S.2    Kato, K.3    Takagi, Y.4    Uetake, H.5    Sugihara, K.6
  • 17
    • 37149041833 scopus 로고    scopus 로고
    • Molecular classification and correlates in colorectal cancer
    • O gino S and Goel A: Molecular classification and correlates in colorectal cancer. J Mol Diagn 10: 13-27, 2008.
    • (2008) J Mol Diagn , vol.10 , pp. 13-27
    • Ogino, S.1    Goel, A.2
  • 20
    • 34248160372 scopus 로고    scopus 로고
    • Dependence receptors: When apoptosis controls tumor progression
    • Bernet A and Mehlen P: Dependence receptors: when apoptosis controls tumor progression. Bull Cancer 94: E12-E17, 2007.
    • (2007) Bull Cancer , vol.94
    • Bernet, A.1    Mehlen, P.2
  • 21
    • 23044459218 scopus 로고    scopus 로고
    • Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers
    • DOI 10.1038/sj.bjc.6602656
    • Mehlen P and Llambi F: Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers. Br J Cancer 93: 1-6, 2005. (Pubitemid 41076245)
    • (2005) British Journal of Cancer , vol.93 , Issue.1 , pp. 1-6
    • Mehlen, P.1    Llambi, F.2
  • 22
    • 4344716258 scopus 로고    scopus 로고
    • Role of the dependence receptor DCC in colorectal cancer pathogenesis
    • DOI 10.1200/JCO.2004.02.019
    • Mehlen P and Fearon ER: Role of the dependence receptor DCC in colorectal cancer pathogenesis. J Clin Oncol 22: 3420-3428, 2004. (Pubitemid 41103701)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.16 , pp. 3420-3428
    • Mehlen, P.1    Fearon, E.R.2
  • 23
    • 34547927238 scopus 로고    scopus 로고
    • Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis
    • DOI 10.1038/sj.onc.1210347, PII 1210347
    • Rodrigues S, De Wever O, Bruyneel E, Rooney RJ and Gespach C: Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis. Oncogene 26: 5615-5625, 2007. (Pubitemid 47267839)
    • (2007) Oncogene , vol.26 , Issue.38 , pp. 5615-5625
    • Rodrigues, S.1    De Wever, O.2    Bruyneel, E.3    Rooney, R.J.4    Gespach, C.5
  • 24
    • 36549009090 scopus 로고    scopus 로고
    • Inactivation of the UNC5C Netrin-1 Receptor Is Associated With Tumor Progression in Colorectal Malignancies
    • DOI 10.1053/j.gastro.2007.08.009, PII S0016508507014552
    • Bernet A, Mazelin L, Coissieux MM, et al.: Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies. Gastroenterology 133: 1840-1848, 2007. (Pubitemid 350186160)
    • (2007) Gastroenterology , vol.133 , Issue.6 , pp. 1840-1848
    • Bernet, A.1    Mazelin, L.2    Coissieux, M.3    Gadot, N.4    Ackerman, S.L.5    Scoazec, J.6    Mehlen, P.7
  • 25
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER and Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 61: 759-767, 1990.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 26
    • 0025056930 scopus 로고
    • Identification of a chromosome 18q gene that is altered in colorectal cancers
    • Fearon ER, Cho KR, Nigro JM, et al.: Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 247: 49-56, 1990.
    • (1990) Science , vol.247 , pp. 49-56
    • Fearon, E.R.1    Cho, K.R.2    Nigro, J.M.3
  • 27
    • 33745684527 scopus 로고    scopus 로고
    • Metastasis: A question of life or death
    • Mehlen P and Puisieux A: Metastasis: a question of life or death. Nat Rev Cancer 6: 449-458, 2006.
    • (2006) Nat Rev Cancer , vol.6 , pp. 449-458
    • Mehlen, P.1    Puisieux, A.2
  • 28
    • 0035114554 scopus 로고    scopus 로고
    • Adjuvant therapy of colon cancer
    • Macdonald JS and Astrow AB: Adjuvant therapy of colon cancer. Semin Oncol 28: 30-40, 2001. (Pubitemid 32172408)
    • (2001) Seminars in Oncology , vol.28 , Issue.1 , pp. 30-40
    • Macdonald, J.S.1    Astrow, A.B.2
  • 29
    • 0031982505 scopus 로고    scopus 로고
    • Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer
    • O 'Connell MJ, Laurie JA, Kahn M, et al.: Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer. J Clin Oncol 16: 295-300, 1998.
    • (1998) J Clin Oncol , vol.16 , pp. 295-300
    • O'Connell, M.J.1    Laurie, J.A.2    Kahn, M.3
  • 30
    • 17544374369 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in curative resected colon carcinoma: 5-fluorouracil/leucovorin versus high-dose 5-fluorouracil 24-h infusion/leucovorin versus high-dose 5-fluorouracil 24-h infusion
    • DOI 10.1007/s00384-004-0657-6
    • Arkenau HT, Rettig K and Porschen R: Adjuvant chemotherapy in curative resected colon carcinoma: 5-fluorouracil/leucovorin versus high-dose 5-fluorouracil 24-h infusion/leucovorin versus high-dose 5-fluorouracil 24-h infusion. Int J Colorectal Dis 20: 258-261, 2005. (Pubitemid 40553005)
    • (2005) International Journal of Colorectal Disease , vol.20 , Issue.3 , pp. 258-261
    • Arkenau, H.T.1    Rettig, K.2    Porschen, R.3
  • 31
    • 33947398364 scopus 로고    scopus 로고
    • Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites
    • DOI 10.1016/j.canlet.2006.08.014, PII S0304383506005179
    • Moriguchi K, Yamashita S, Tsujino Y, Tatematsu M and Ushijima T: Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites. Cancer Lett 249: 178-187, 2007. (Pubitemid 46452925)
    • (2007) Cancer Letters , vol.249 , Issue.2 , pp. 178-187
    • Moriguchi, K.1    Yamashita, S.2    Tsujino, Y.3    Tatematsu, M.4    Ushijima, T.5
  • 33
    • 10344239412 scopus 로고    scopus 로고
    • Netrin-1 and its receptors in tumorigenesis
    • Arakawa H: Netrin-1 and its receptors in tumorigenesis. Nat Rev Cancer 4: 978-987, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 978-987
    • Arakawa, H.1
  • 34
    • 23044446171 scopus 로고    scopus 로고
    • P53, apoptosis and axon-guidance molecules
    • Arakawa H: p53, apoptosis and axon-guidance molecules. Cell Death Differ 12: 1057-1065, 2005.
    • (2005) Cell Death Differ , vol.12 , pp. 1057-1065
    • Arakawa, H.1
  • 36
    • 33646071894 scopus 로고    scopus 로고
    • Decitabine improves patient outcomes in myelodysplastic syndromes: Results of a phase III randomized study
    • K antarjian H, Issa JP, Rosenfeld CS, et al.: Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer 106: 1794-1803, 2006.
    • (2006) Cancer , vol.106 , pp. 1794-1803
    • Kantarjian, H.1    Issa, J.P.2    Rosenfeld, C.S.3
  • 37
    • 77449149374 scopus 로고    scopus 로고
    • Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia
    • Cashen AF, Schiller GJ, O'Donnell MR and DiPersio JF: Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia. J Clin Oncol 28: 556-561, 2010.
    • (2010) J Clin Oncol , vol.28 , pp. 556-561
    • Cashen, A.F.1    Schiller, G.J.2    O'Donnell, M.R.3    DiPersio, J.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.