Metabotropic glutamate receptors: Potential therapeutic applications of recently disclosed new chemical entities

Expert Opinion on Therapeutic Patents

Volumn 14, Issue 11, 2004, Pages 1593-1604

  Sabbatini, Fabio Maria ^a   Micheli, Fabrizio ^b  

^a GSK   (Italy)

^b NONE

Author keywords

Agonist; Allosteric modulator; Antagonist; Anxiety; Cognitive disorders; Depression; Metabotropic glutamate receptor (mGlu); Pain; Schizophrenia

Indexed keywords

1 (PYRIDIN 2 YL)PIPERAZINE DERIVATIVE; 1,3 BISARYLTETRAZOLE DERIVATIVE; 2 AMINO 3 (3,4 DICHLOROBENZYLOXY) 6 FLUOROBICYCLO[3.1.0]HEXANE 2,6 DICARBOXYLIC ACID; 2 AMINO 6 FLUOROBICYCLO[3.1.0]HEXANE 2,6 DICARBOXYLIC ACID; 2 METHYL 6 (2 PHENYLVINYL)PYRIDINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; ACETYLENE DERIVATIVE; BENZENE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; CLOZAPINE; EGLUMETAD; GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYMETHYLGLUTAMIC ACID; IMIDAZOTHIAZOLE DERIVATIVE; INOSITOL PHOSPHATE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; QUINOLINE DERIVATIVE; TETRAHYDROHETEROCYCLOAZEPINYLPYRIMIDINE DERIVATIVE; TETRAZOLE DERIVATIVE; THIAZOLE DERIVATIVE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AMINO TERMINAL SEQUENCE; BRAIN INFARCTION; BRAIN INJURY; COGNITIVE DEFECT; DEMENTIA; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG RECEPTOR BINDING; DRUG STRUCTURE; EPILEPSY; HUMAN; HYPOGLYCEMIA; HYPOXIA; MOLECULAR CLONING; NEUROLOGIC DISEASE; NONHUMAN; PARKINSON DISEASE; PATENT; PROTEIN DOMAIN; PROTEIN FUNCTION; REVIEW; SCHIZOPHRENIA; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 8444229676     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.14.11.1593     Document Type: Review

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