Synthesis, central and peripheral benzodiazepine receptor affinity of pyrazole and pyrazole-containing polycyclic derivatives

Farmaco

Volumn 59, Issue 11, 2004, Pages 849-856

  Campagna, Francesco ^a   Palluotto, Fausta ^a   Carotti, Angelo ^a   Maciocco, Elisabetta ^b  

^a UNIVERSITY OF BARI   (Italy)

^b Perinatology Child Hlth Univ S   (Italy)

Author keywords

1 Aryl 1,4 dihydro indeno 1,2 c pyrazoles; Binding assay; Central benzodiazepine receptor; Peripheral benzodiazepine receptor; Structure activity relationships

Indexed keywords

1 (4 CHLOROPHENYL)INDENO[1,2 C]PYRAZOL 4(1H) ONE; BENZODIAZEPINE RECEPTOR; BUTYL 1 (2 CHLOROPHENYL) 4 OXO 1,4 DIHYDROINDENOL[1,2 C]PYRAZOLE 3 CARBOXYLATE; ISOBUTYL 1 (2 CHLOROPHENYL) 4 OXO 1,4 DIHYDROINDENO[1,2 C]PYRAZOLE 3 CARBOXYLATE; N,N DIETHYL 1 PHENYL 1,4 DIHYDROINDENO[1,2 C]PYRAZOLE 3 CARBOXAMIDE; POLYCYCLIC HYDROCARBON; PYRAZOLE; PYRAZOLE DERIVATIVE; TRICYCLIC AROMATIC COMPOUND; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; IC 50; MALE; NONHUMAN; RAT;

ANIMALS; INHIBITORY CONCENTRATION 50; LIGANDS; MALE; POLYCYCLIC HYDROCARBONS, AROMATIC; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A;

EID: 8444219757     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2004.05.008     Document Type: Article

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