Synthesis and structure-affinity relationships at the central benzodiazepine receptor of pyridazino[4,3-b]indoles and Indeno[1,2-c]pyridazines

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 8, 1999, Pages 1533-1538

  Campagna, F ^a   Palluotto, F ^a   Carotti, A ^a   Casini, G ^a   Genchi, G ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Benzodiazepine receptor; Binding assay; Indeno 1,2 c pyridazines; Pyridazino 4,3 b indoles; Structure activity relationships

Indexed keywords

BENZODIAZEPINE RECEPTOR; FLUNITRAZEPAM; INDOLE DERIVATIVE; PYRIDAZINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; MOLECULAR MODEL; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION;

HYDROGEN BONDING; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PYRIDAZINES; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032811376     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00093-0     Document Type: Article

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