Inhibition of itch-related responses at spinal level in rats

Acta Physiologica Hungarica

Volumn 98, Issue 4, 2011, Pages 480-490

  Horvath, G ^a   Joo, G ^a   Kekesi, G ^a   Farkas, I ^b   Tuboly, G ^c   Petrovszki, Z ^a   Benedek, G ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

ketamine; kynurenic acid; naltrexone; pruritus; rat; spinal cord

Indexed keywords

5 METHOXYTRYPTAMINE; KETAMINE; KYNURENIC ACID; NALTREXONE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DRUG RESPONSE; INTRATHECAL DRUG ADMINISTRATION; LOWER LEG; MALE; NONHUMAN; PRURITUS; RAT; SKIN;

5-METHOXYTRYPTAMINE; ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; EXCITATORY AMINO ACID ANTAGONISTS; INJECTIONS, SPINAL; KETAMINE; KYNURENIC ACID; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; PRURITUS; RATS; RATS, WISTAR; SPINAL CORD;

EID: 84255209589     PISSN: 0231424X     EISSN: 15882683     Source Type: Journal    
DOI: 10.1556/APhysiol.98.2011.4.12     Document Type: Article

References (53)

1. Akiyama T, Merrill AW, Zanotto K, Carstens MI, Carstens E: Scratching behavior and Fos expression in superficial dorsal horn elicited by protease-activated receptor agonists and other itch mediators in mice. J. Pharmacol. Exp. Ther. 329, 945-951 (2009)
2. Akiyama T, Merrill AW, Carstens MI, Carstens E: Activation of superficial dorsal horn neurons in the mouse by a PAR-2 agonist and 5-HT: potential role in itch. J. Neurosci. 29, 6691-6699 (2009)
3. Andrew D, Craig AD: Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch. Nat. Neurosci. 4, 72-77 (2001) (Pubitemid 32095528)
4. Ballantyne JC, Loach AB, Carr DB: Itching after epidural and spinal opiates. Pain 33, 149-160 (1988)
5. Berendsen HHG, Boekkamp CLE: A peripheral 5-HT-1D-like receptor involved in serotoninergic induced hindlimb scratching in rats. Eur. J. Pharmacol. 194, 201-208 (1991)
6. Berendsen HHG, Broekkamp CLE: Age dependence of 5-methoxytryptamine- induced hindlimb scratching in rats. Eur. J. Pharmacol. 199, 107-109 (1991)
7. Bernstein JE, Swift RM, Soltani K, Lorincz AL: Anti-pruritic effect of an opiate antagonist, naloxone hydrochloride. J. Invest. Dermatol. 78, 82-83 (1982) (Pubitemid 12207162)
8. Buvanendran A, McCarthy RJ, Kroin JS, Leong W, Perry P, Tuman KJ: Intrathecal magnesium prolongs fentanyl analgesia: a prospective, randomized, controlled trial. Anesth. Analg. 95, 661-666 (2002) (Pubitemid 35006861)
9. Carstens E: Responses of rat spinal dorsal horn neurons to intracutaneous microinjection of histamine, capsaicin and other irritans. J. Neurophysiol. 77, 2499-2514 (1997) (Pubitemid 27209218)
10. Carstens EE, Carstens MI, Simons CT, Jinks SL: Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats. NeuroReport 21, 303-308 (2010)
11. Coggeshall RE, Carlton SM: Receptor localization in the mammalian dorsal horn and primary afferent neurons. Brain Res. Rev. 24, 28-66 (1997) (Pubitemid 27293807)
12. Costa R, Manjavachi MN, Motta EM, Marotta DM, Juliano L, Torres HA, Pesquero JB, Calixto JB: The role of kinin B-1 and B-2 receptors in the scratching behaviour induced by proteinase-activated receptor-2 agonists in mice. Br. J. Pharmacol. 159, 888-897 (2010)
13. Davidson S, Zhang X, Khasabov SG, Simone DA, Giesler GJJr: Relief of itch by scratching: state-dependent inhibition of primate spinotalamic tract neurons. Nat. Neurosci. 12, 544-546 (2009)
14. Dickenson AH: Spinal cord pharmacology of pain. Br. J. Anaesth. 75, 193-200 (1995)
15. Dobos I, Toth K, Kekesi G, Joo G, Csullog E, Klimscha W, Benedek G, Horvath G: The significance of intrathecal catheter location in rats. Anesth. Analg. 96, 487-492 (2003) (Pubitemid 36125770)
16. Ganesh A, Maxwell LG: Pathophysiology and management of opioid-induced pruritus. Drugs 67, 2323-2333 (2007) (Pubitemid 350071045)
17. Greaves MW: Recent advances in pathophysiology and current management of itch. Ann. Acad. Med. Singapore 36, 788-792 (2007) (Pubitemid 350219088)
18. Han DW, Hong SW, Kwon JY, Lee JW, Kim KJ: Epidural ondansetron is more effective to prevent postoperative pruritus and nausea than intravenous ondansetron in elective cesarean delivery. Acta. Obstet. Gynecol. Scand. 86, 683-687 (2007) (Pubitemid 46801785)
19. Horta ML, Ramos L, Goncalves ZR: The inhibition of epidural morphine-induced pruritus by epidural droperidol. Anesth. Analg. 90, 638-641 (2000) (Pubitemid 30117525)
20. Horvath G, Joo G, Dobos I, Klimscha W, Toth G, Benedek G: The synergistic antinociceptive interactions of endomorphin-1 with dexmedetomidine and/or S(+)-ketamine in rats. Anesth. Analg. 93, 1018-1024 (2001) (Pubitemid 32905997)
21. Ikoma A, Rukwied R, Stander S, Steinhoff M, Miyachi Y, Schmelz M: Neurophysiology of pruritus. Arch. Dermatol. 139, 1475-1478 (2003)
22. Ikoma A, Steinhoff M, Stander S, Yosipovitch G, Schmelz M: The neurobiology of itch. Nat. Rev. Neurosci. 7, 535-547 (2006) (Pubitemid 43995431)
23. Inagaki N, Igeta K, Kim JF, Nagao M, Shiraishi N, Nakamura N, Nagai H: Involvement of unique machanisms in the induction of scratching behavior in BALB/c mice by compound 48/80. Eur. J. Pharmacol. 448, 175-183 (2002) (Pubitemid 34874585)
24. Jeon Y, Hwang J, Kang J, Han S, Rhee K, Oh Y: Effects of epidural naloxone on pruritus induced by epidural morphine: a randomized controlled trial. Int. J. Obstet. Anesth. 14, 22-25 (2005) (Pubitemid 41201402)
25. Jinks SL, Carstens E: Spinal NMDA receptor involvement in expansion of dorsal horn neuronal receptive field area produced by intracutaneous histamine. J. Neurophysiol. 79, 1613-1618 (1998) (Pubitemid 28183302)
26. Jinks SL, Carstens E: Superficial dorsal horn neurons identified by intracutaneous histamine: chemonociceptive responses and modulation by morphine. J. Neurophysiol. 84, 616-627 (2000) (Pubitemid 30655589)
27. Jinks SL, Carstens E: Responses of superficial dorsal horn neurons to intradermal serotonin and other irritans: comparison with scratching behavior. J. Neurophysiol. 87, 1280-1289 (2002) (Pubitemid 34670795)
28. Johanek LM, Meyer RA, Hartke T, Hobelmann JG, Maine DN, LaMotte RH, Ringkamp M: Psychophysical and physiological evidence for parallel afferent pathways mediating the sensation of itch. J. Neurosci. 27, 7490-7497 (2007) (Pubitemid 47066576)
29. Joo G, Horvath G, Klimscha W, Kekesi G, Dobos I, Szikszay M, Benedek G: The effects of ketamine and its enantiomers on the morphine- or dexmedetomidine-induced antinociception after intrathecal administration in rats. Anesthesiology 93, 231-241 (2000) (Pubitemid 30436698)
30. Ko MCH, Song MS, Edwards T, Lee H, Naughton NN: The role of central ?-opioid receptors in opioid-induced itch in primates. J. Pharmacol. Exp. Ther. 310, 169-176 (2004) (Pubitemid 38812708)
31. Kuraishi Y, Nagasawa T, Hayashi K, Satoh M: Scratching behavior induced by pruritogenic but not algesiogenic agents in mice. Eur. J. Pharmacol. 275, 229-233 (1995)
32. Kuraishi Y, Yageta Y, Konno M, Andoh T, Yamaguchi-Miyamoto T, Nojima H: Intracisternal, but not intrathecal, injection of naloxone inhibits cutaneous itch-related response in mice. Biol. Pharm. Bull. 31, 2143-2145 (2008)
33. Kuraishi Y, Yamaguchi T, Miyamoto T: Itch-scratch responses induced by opioids through central mu opioid receptors in mice. J. Biomed. Sci. 7, 248-252 (2000) (Pubitemid 30307744)
34. Maekawa T, Yamaguchi-Miyamoto T, Nojima H, Kuraishi Y: Effects of naltrexone on spontaneous itchassociated responses in NC mice with chronic dermatitis. Jpn. J. Pharmacol. 90, 193-196 (2002) (Pubitemid 35291306)
35. Nojima H, Carstens E: Quantitative assessment of directed hind limb scratching behavior as a rodent itch model. J. Neurosci. Methods 126, 137-143 (2003) (Pubitemid 36694154)
36. Nojima H, Carstens MI, Carstens E: C-fos expression in superficial dorsal horn of cervical spinal cord associated with spontaneous scratching in rats with dry skin. Neurosci. Lett. 347, 62-64 (2003) (Pubitemid 36831107)
37. Nojima H, Cuellar JM, Simons CT, Carstens MI, Carstens E: Spinal c-Fos expression associated with spontaneous biting in a mouse model of dry skin pruritus. Neurosci. Lett. 361, 79-82 (2004) (Pubitemid 38609221)
38. Nojima H, Simons CT, Cuellar JM, Carstens MI, Moore JA, Carstens E: Opioid modulation of scratching and spinal c-fos expression evoked by intradermal serotonin. J. Neurosci. 23, 10784-10790 (2003) (Pubitemid 37499684)
39. Ohshiro H, Tonai-Kachi H, Ichikawa K: GPR35 is a functional receptor in rat dorsal root ganglion neurons. Biochem. Biophys. Res. Commun. 365, 344-348 (2008) (Pubitemid 350137295)
40. Okutomi T, Saito M, Mochizuki J, Amano K: Prophylactic epidural naloxone reduces the incidence and severity of neuraxial fentanyl-induced pruritus during labour analgesia in primiparous parturients. Can. J. Anaesth. 50, 961-962 (2003) (Pubitemid 38139546)
41. Omori Y, Andoh T, Shirakawa H, Ishida H, Hachiga T, Kuraishi Y: Itch-related responses of dorsal horn neurons to cutaneous allergic stimulation in mice. NeuroReport 20, 478-481 (2009)
42. Onigbogi O, Ajayi AA, Ukponmwen OE: Mechanisms of chloroquine-induced body-scratching behavior in rats: evidence of involvement of endogenous opioid peptides. Pharmacol. Biochem. Behav. 65, 333-337 (2000) (Pubitemid 30100281)
43. Pereira EF, Hilmas C, Santos MD, Alkondon M, Maelicke A, Albuquerque EX: Unconventional ligands and modulators of nicotinic receptors. J. Neurobiol. 53, 479-500 (2002) (Pubitemid 35375580)
44. Ren K, Williams GM, Hylden JLK, Ruda MA, Dubner R: The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats. Eur. J. Pharmacol. 219, 235-243 (1992)
45. Schmelz M: Itch and pain. Neurosci. Biobehav. Rev. 34, 171-176 (2010)
46. Simone DA, Zhang X, Li J, Zhang JM, Honda CN, LaMotte RH, Giesler GJ, Jr.: Comparison of responses of primate spinothalamic tract neurons to pruritic and algogenic stimuli. J. Neurophysiol. 91, 213-222 (2004) (Pubitemid 38084366)
47. Sun YG, Chen Z-F: A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord. Nature 448, 700-703 (2007) (Pubitemid 47236861)
48. Sun YG, Zhao ZQ, Meng XL, Yin J, Liu XY, Chen ZF: Cellular basis if itch sensation. Science 325, 1531-1534 (2009)
49. Thomsen JS, Petersen MB, Benfeldt E, Jensen SB, Serup J: Scratch induction in the rat by intradermal serotonin: a model for pruritus. Acta Derm. Venereol. 81, 250-254 (2001) (Pubitemid 32977102)
50. Wang J, Simonavicius N, Wu X, Swaminath G, Reagan J, Tian H, Ling L: Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J. Biol. Chem. 281, 22021-22028 (2006) (Pubitemid 44181906)
51. Wiesenfeld-Hallin Z: Combined opioid-NMDA antagonist therapies. Drugs 55, 1-4 (1998)
52. Yaksh TL, Rudy TA: Chronic catheterization of the spinal subarachnoid space. Physiol. Behav. 17, 1031-1036 (1976) (Pubitemid 8063691)
53. Yamaguchi T, Nagasawa T, Satoh M, Kuraishi Y: Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice. Neurosci. Res. 35, 77-83 (1999) (Pubitemid 29518398)