Quantitative assessment of directed hind limb scratching behavior as a rodent itch model

Journal of Neuroscience Methods

Volumn 126, Issue 2, 2003, Pages 137-143

  Nojima, Hiroshi ^a   Carstens, E ^b  

^a UNIVERSITY OF TOYAMA   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Itch; Naltrexone; Rat; Scratch reflex; Scratching; Serotonin

Indexed keywords

NALTREXONE; SEROTONIN; SODIUM CHLORIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HINDLIMB; MALE; NECK; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SCRATCHING; SKIN; VALIDATION PROCESS;

EID: 0038798016     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0270(03)00074-8     Document Type: Article

References (31)

1. Andoh T., Nagasawa T., Satoh M., Kuraishi Y. Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice. J. Pharmacol. Exp. Ther. 286:1998;1140-1145.
2. Baev K.V., Esipenko V.B., Shimansky Y.P. Afferent control of central pattern generators: experimental analysis of scratching in the decerebrate cat. Neuroscience. 40:1991;239-256.
3. Balaskas E.V. Histamine and serotonin in uremic pruritus: effect of ondansetrom in CAPD-pruritic patients. Nephron. 78:1998;395-402.
4. Barney C.C., Morrison C.M., Renkema L.A., Vergoth C. Opioid modulation of thermal dehydration-induced thirst in rats. Pharmacol. Biochem. Behav. 43:1992;1065-1070.
5. Berkinblit M.B., Deliagina T.G., Feldman A.G., Gelfand I.M., Orlovsky G.N. Generation of scratching. II. Nonregular regimes of generation. J. Neurophysiol. 41:1978;1058-1069.
6. Bernstein J.E., Swift R. Relief of intractable pruritus with naloxone. Arch. Dermatol. 115:1979;1366-1367.
7. Bernstein J.E., Swift R., Soltani K., Lorincz A.L. Antipruritic effect of an opiate antagonist, naloxone hydrochloride. J. Invest. Dermatol. 78:1982;82-83.
8. Bossut D., Frenk H., Mayer D.J. Is substance P a primary afferent neurotransmitter for nociceptive input? II. Spinalization does not reduce and intrathecal morphine potentiates behavioral responses to substance P. Brain Res. 445:1988;232-239.
9. Cuellar J.M., Jinks S.L., Simons C.T., Carstens E. Deletion of the preprotachykinin A gene in mice does not reduce scratching behavior elicited by intradermal serotonin. Neurosci. Lett. 339:2003;72-76.
10. DeCastro-Costa M., Gybels J., Kupers R., Van Hees J. Scratching behaviour in arthritic rats: a sign of chronic pain or itch. Pain. 29:1987;123-131.
11. Degtyarenko A.M., Kaufman M.P. Fictive locomotion and scratching inhibit dorsal horn neurons receiving thin fiber afferent input. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279:2000;R394-R403.
12. Frenk H., Bossut D., Urca G., Mayer D.J. Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds. Brain Res. 455:1988;223-231.
13. Graziano F.M. Mast cells and mast cell products. Methods Enzymol. 162:1988;501-522.
14. Grillner S. Locomotion in vertebrates: central mechanisms and reflex interaction. Physiol. Rev. 55:1975;247-304.
15. Gustafsson B. Cytofluorometric analysis of anaphylactic secretion of 5-hydroxytryptamine and heparin from rat mast cells. Int. Arch. Allergy Appl. Immunol. 63:1980;121-128.
16. Hagermark O. Itch mediators. Semin. Dermatol. 14:1995;271-276.
17. Heyer G., Dotzer M., Diepgen T.L., Handwerker H.O. Opiate and H1 antagonist effects on histamine induced pruritus and alloknesis. Pain. 73:1997;239-243.
18. Jinks S.L., Carstens E. Responses of superficial dorsal horn neurons to intradermal serotonin and other irritants: comparison with scratching behavior. J. Neurophysiol. 87:2002;1280-1289.
19. Königstein H. Experimental study of itch stimuli in animals. Arch. Dermatol. Syphilol. 57:1948;829-849.
20. Kuhta P.C., Smith J.L. Scratch responses in normal cats: hindlimb kinematics and muscle synergies. J. Neurophysiol. 64:1990;1653-1667.
21. Kuraishi Y., Nagasawa T., Hayashi K., Satoh M. Scratching behavior induced by pruritogenic but not algesiogenic agents in mice. Eur. J. Pharmacol. 275:1995;229-233.
22. Purcell W.M., Cohen D.L., Hanahoe T.H. Comparison of histamine and 5-hydroxytryptamine content and secretion in rat mast cells isolated from different anatomical locations. Int. Arch. Allergy Appl. Immunol. 90:1989;382-386.
23. Schwörer H., Ramadori G. Improvement of cholestatic pruritus by ondansetron [letter]. Lancet. 341:1993;1277.
24. Thomas D.A., Hammond D.L. Microinjection of morphine into the rat medullary dorsal horn produces a dose-dependent increase in facial scratching. Brain Res. 695:1995;267-270.
25. Thomas D.A., Williams G.M., Iwata K., Kenshalo D.R. Jr, Dubner R. The medullary dorsal horn. A site of action of morphine in producing facial scratching in monkeys. Anesthesiology. 79:(3):1993;548-554.
26. Thomsen J.S., Petersen M.B., Benfeldt E., Jensen S.B., Serup J. Scratch induction in the rat by intradermal serotonin: a model for pruritus. Acta Derm.-Venereol. 81:2001;250-254.
27. Tohda C., Yamaguchi T., Kuraishi Y. Intracisternal injection of opioids induces itch-associated response through mu-opioid receptors in mice. Jpn. J. Pharmacol. 74:1997;77-82.
28. Van Wimersma Greidanus T.B., Maigret C. Grooming behavior induced by substance P. Eur. J. Pharmacol. 154:1988;217-220.
29. Van Wimersma Greidanus T.B., Maigret C. Neuromedin-induced excessive grooming/scratching behavior is suppressed by naloxone, neurotensin and a dopamine D1 receptor antagonist. Eur. J. Pharmacol. 209:1991;57-61.
30. Wilcox G.L. Pharmacological studies of grooming and scratching behavior elicited by spinal substance P and excitatory amino acids. Ann. New York Acad. Sci. 525:1988;228-236.
31. Yamaguchi T., Nagasawa T., Satoh M., Kuraishi Y. Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice. Neurosci. Res. 35:1999;77-83.