Involvement of unique mechanisms in the induction of scratching behavior in BALB/c mice by compound 48/80

European Journal of Pharmacology

Volumn 448, Issue 2-3, 2002, Pages 175-183

  Inagaki, Naoki ^a   Igeta, Katsuhiro ^a   Kim, John Fan ^a   Nagao, Masafumi ^a   Shiraishi, Noriko ^a   Nakamura, Nobuaki ^a   Nagai, Hiroichi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

(Mouse); 5 HT (5 hydroxypryptamine, serotonin); Compound 48 80; Histamine; Mast cell; MicroAct; Scratching behavior

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; CINCHOCAINE; COMPOUND 48-80; CYPROHEPTADINE; ENZYME INHIBITOR; HISTAMINE H1 RECEPTOR ANTAGONIST; INDOMETACIN; ISRAPAFANT; KETOTIFEN; METHYSERGIDE; MU OPIATE RECEPTOR; NALOXONE; NALTREXONE; PROSTAGLANDIN SYNTHASE INHIBITOR; SEROTONIN ANTAGONIST; TERFENADINE; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; 4 METHOXY N METHYLPHENETHYLAMINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL ACTIVATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; MALE; MAST CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; SCRATCHING; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; EVALUATION; GENETICS; METABOLISM; METHODOLOGY; OBSERVATION; PATHOLOGY; PHYSIOLOGY; PRURITUS; SKIN;

ANIMAL; BEHAVIOR, ANIMAL; COMPARATIVE STUDY; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; OBSERVATION; P-METHOXY-N-METHYLPHENETHYLAMINE; PRURITUS; SKIN; ANIMALS;

EID: 0037135028     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01933-7     Document Type: Article

References (35)

1. 4 in substance P-induced itch-associated response in mice
2. Itching after epidural and spinal opiates
3. Differential release of histamine and eicosanoids from human skin mast cells activated by IgE-dependent and non-immunological stimuli
4. Effects of naloxone infusions in patients with the pruritus of cholestasis. A double-blind, randomized, controlled trial
5. Pruritometer 2: Portable recording system for the quantification of scratching as objective criterion for the pruritus
6. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
7. Evaluation of scratch movements by a new scratch-monitor to analyze nocturnal itching in atopic dermatitis
8. Mast cells in rat gastrointestinal mucosa: 3. Reactivity towards compound 48/80
9. Inhibitory effect of cloxacepride on compound 48/80-induced histamine and serotonin release from rat mast cells
10. L-663,536 (MK-886) (3-[1-(4-chlorobenzyl9-3-t-butyl-thio-5-isopropylindol-2-yl)-2, 2-dimethylpropanoic acid], a novel, orally active leukotriene biosynthesis inhibitor
11. Studies on vascular permeability increasing factors involved in 48-hour homologous PCA in the mouse ear
12. Homologous passive cutaneous anaphylaxis in various strains of mice
13. 2 receptors in passive cutaneous anaphylaxis-induced scratching behavior in ICR mice
14. Evaluation of anti-scratch properties of oxatomide and epinastine in mice
15. Inhibition of passive cutaneous anaphylaxis-associated scratching behavior by μ-opioid receptor antagonists in ICR mice
16. Scratching behavior in various strains of mice
17. Guideline for animal experimentation
18. Effects of antihistamines on cutaneous reactions and influx of eosinophils after local injection of PAF, kallikrein, compound 48/80 and histamine in patients with chronic urticaria and healthy subjects
19. Antipruritic effect of DA-5018, a capsaicin derivative, in mice
20. Histamine release induced from mast cells by active components of compound 48/80
21. Scratching behavior induced by pruritogenic but not algesiogenic agents in mice
22. Inhibition of passive cutaneous anaphylaxis by several histamine H1 and serotonin antagonists in the rat
23. Scratching behavior in mice associated with IgE-mediated allergic cutaneous reaction and its pharmacological characterization
24. Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients: A dermal microdialysis study
25. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents
26. Effects of topically applied clobetasol-17-propionate on histamine release in human skin
27. Pharmacological actions of Y-24180, a new specific antagonist of platelet activating factor (PAF): II. Interaction with PAF and benzodiazepine receptors
28. Pharmacological actions of Y-24180: I. A potent and specific antagonist of platelet-activating factor
29. Itch and atopic dermatitis: Clinical and experimental studies
30. Patients' perception of itch induced by histamine, compound 48/80 and wool fibers in atopic dermatitis
31. Cloned mouse mast cells and normal mouse peritoneal mast cells. Determination of serotonin content and ability to synthesize serotonin in vitro
32. Characterization of a behavioral model for peripherally evoked itch suggests platelet-activating factor as a potent pruritogen
33. Characterization of receptor subtypes involved in prostanoid-induced conjunctival pruritus and their role in mediating allergic conjunctival itching
34. 2 receptors in mice
35. Characterization of itch-associated responses of NC mice with mite-induced chronic dermatitis