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Volumn 7, Issue 8, 2011, Pages 813-820

Exercise training and grape seed extract co-administration improve endothelial dysfunction of mesenteric vascular bed in STZ-induced diabetic rats

Author keywords

Diabetic vascular complication; Exercise; Grape seed extract; Mesenteric vascular bed; Plasma antioxidant capacity

Indexed keywords

ACETYLCHOLINE; GLUCOSE; GRAPE SEED EXTRACT; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; STREPTOZOCIN;

EID: 84255177694     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2011.813.820     Document Type: Article
Times cited : (7)

References (44)
  • 1
    • 79958243683 scopus 로고    scopus 로고
    • Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits
    • Akar, F., M.B. Pektas, C. Tufan, S. Soylemez and A. Sepici, 2011. Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits. Cardiovas. Drugs Ther., 25: 119-131.
    • (2011) Cardiovas. Drugs Ther , vol.25 , pp. 119-131
    • Akar, F.1    Pektas, M.B.2    Tufan, C.3    Soylemez, S.4    Sepici, A.5
  • 2
    • 53749104222 scopus 로고    scopus 로고
    • Effect of grape seed extract on lead induced hypertension and heart rate in rat
    • Badavi, M., F.Z. Mehrgerdi, A. Sarkaki, M.K.G. Naseri and M. Dianat, 2008. Effect of grape seed extract on lead induced hypertension and heart rate in rat. Pak. J. Biol. Sci., 11: 882-887.
    • (2008) Pak. J. Biol. Sci , vol.11 , pp. 882-887
    • Badavi, M.1    Mehrgerdi, F.Z.2    Sarkaki, A.3    Naseri, M.K.G.4    Dianat, M.5
  • 3
    • 0030586361 scopus 로고    scopus 로고
    • The Ferric Reducing Ability of Plasma (FRAP) as a measure of antioxidant power: The FRAP assay
    • Benzie, I.F.F. and J. J. Strain, 1996. The Ferric Reducing Ability of Plasma (FRAP) as a measure of antioxidant power: The FRAP assay. Anal. Biochem., 239: 70-76.
    • (1996) Anal. Biochem , vol.239 , pp. 70-76
    • Benzie, I.F.F.1    Strain, J.J.2
  • 4
    • 0035116150 scopus 로고    scopus 로고
    • Diabetes and endothelial dysfunction: A clinical perspective
    • Calles-Escandon, J. and M. Cipolla, 2001. Diabetes and endothelial dysfunction: A clinical perspective. Endocrinol. Rev., 22: 36-52.
    • (2001) Endocrinol. Rev , vol.22 , pp. 36-52
    • Calles-Escandon, J.1    Cipolla, M.2
  • 5
    • 0035399658 scopus 로고    scopus 로고
    • Effect of alpha-lipoic acid on vascular responses and nociception in diabetic rats
    • Cameron, N.E., A.M. Jack and M.A. Cotter, 2001. Effect of alpha-lipoic acid on vascular responses and nociception in diabetic rats. Free Radic. Biol. Med., 31: 125-135.
    • (2001) Free Radic. Biol. Med , vol.31 , pp. 125-135
    • Cameron, N.E.1    Jack, A.M.2    Cotter, M.A.3
  • 8
    • 0036712066 scopus 로고    scopus 로고
    • Effects of the protein kinase C [3 inhibitor LY333531 on neural and vascular function in rats with streptozotocin-induced diabetes
    • Cotter, M.A., A.M. Jack and N.E. Cameron, 2002. Effects of the protein kinase C [3 inhibitor LY333531 on neural and vascular function in rats with streptozotocin-induced diabetes. Clin. Sci., 103: 311-321.
    • (2002) Clin. Sci , vol.103 , pp. 311-321
    • Cotter, M.A.1    Jack, A.M.2    Cameron, N.E.3
  • 9
    • 0032905015 scopus 로고    scopus 로고
    • In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: Effects of improved metabolic control and vitamin
    • Davi, G., G. Ciabattoni, A. Consoli, A. Mezzetti and A. Falco et al., 1999. In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: Effects of improved metabolic control and vitamin E supplementation. Circulation, 99: 224-229.
    • (1999) E Supplementation. Circulation , vol.99 , pp. 224-229
    • Davi, G.1    Ciabattoni, G.2    Consoli, A.3    Mezzetti, A.4    Falco, A.5
  • 10
    • 0029023824 scopus 로고
    • Effects of exercise training on endothelium-dependent peripheral vascular responsiveness
    • Delp, M.D., 1995. Effects of exercise training on endothelium-dependent peripheral vascular responsiveness. Med. Sci. Sports Exerc, 27: 1152-1157.
    • (1995) Med. Sci. Sports Exerc , vol.27 , pp. 1152-1157
    • Delp, M.D.1
  • 11
    • 0023724763 scopus 로고
    • Impairment of endothelium-dependent relaxation in aortae from spontaneously diabetic rats
    • Durante, W., A.K. Sen and F. A. Sunahar, 1988. Impairment of endothelium-dependent relaxation in aortae from spontaneously diabetic rats. Br. J. Pharmacol., 94: 463-468.
    • (1988) Br. J. Pharmacol , vol.94 , pp. 463-468
    • Durante, W.1    Sen, A.K.2    Sunahar, F.A.3
  • 12
    • 38949123212 scopus 로고    scopus 로고
    • Mechanism of the endotheHum-dependent relaxation evoked by a grape seed extract
    • Edirisinghe, I., B. Burton-Freeman and C.T. Kappagoda, 2008. Mechanism of the endotheHum-dependent relaxation evoked by a grape seed extract. Clin. Sci., 114: 331-337.
    • (2008) Clin. Sci , vol.114 , pp. 331-337
    • Edirisinghe, I.1    Burton-Freeman, B.2    Kappagoda, C.T.3
  • 13
    • 33645398098 scopus 로고    scopus 로고
    • The beneficial in vitro effects of lovastatin and chelerythrine on relaxatory response to acetylcholine in the perfused mesentric bed isolated from diabetic rats
    • Fatehi-Hassanabad, Z., M. Imen-Shahidil, M. Fatehil, K. FaiTokhfall and H. Parsaeei, 2006. The beneficial in vitro effects of lovastatin and chelerythrine on relaxatory response to acetylcholine in the perfused mesentric bed isolated from diabetic rats. Eur. J. Pharmacol., 535: 228-233.
    • (2006) Eur. J. Pharmacol , vol.535 , pp. 228-233
    • Fatehi-Hassanabad, Z.1    Imen-Shahidil, M.2    Fatehil, M.3    Faitokhfall, K.4    Parsaeei, H.5
  • 14
    • 67650735222 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular disease: Novel tools give (free) radical insight
    • Fearon, I.M. and S.P. Faux, 2009. Oxidative stress and cardiovascular disease: Novel tools give (free) radical insight. J. Mol. Cell. Cardiol, 47: 372-381.
    • (2009) J. Mol. Cell. Cardiol , vol.47 , pp. 372-381
    • Fearon, I.M.1    Faux, S.P.2
  • 15
    • 60849119548 scopus 로고    scopus 로고
    • Acute exercise and oxidative stress: A 30 year history
    • 10.1186/1476-5918-8-1
    • Fisher-Wellman, K. and R.J. Bloomer, 2009. Acute exercise and oxidative stress: A 30 year history. Dyn. Med., Vol. 8,10.1186/1476-5918-8-1
    • (2009) Dyn. Med , vol.8
    • Fisher-Wellman, K.1    Bloomer, R.J.2
  • 17
    • 0030752939 scopus 로고    scopus 로고
    • Endothelium-dependent hyperpolarization and relaxation in mesenteric arteries from streptozotocin-induced diabetic rats
    • Endothelium-dependent hyperpolarization and relaxation in mesenteric arteries from streptozotocin-induced diabetic rats. Br. J.Pharmacol., 121: 1383-1391.
    • Br. J.Pharmacol , vol.121 , pp. 1383-1391
  • 18
    • 58049140295 scopus 로고    scopus 로고
    • Exercise training enhanced myocardial endothelial nitric oxide synthase (enos) function in diabetic goto-kakizaki (gk) rats
    • Grijalva, J., S. Hicks, X. Zhao, S. Medikayala, P.M. Kaminski, M.S. Wolm and J.G. Edwards, 2008. Exercise training enhanced myocardial endothelial nitric oxide synthase (enos) function in diabetic goto-kakizaki (gk) rats. Cardiovascular Diabetol., 7: 34-34.
    • (2008) Cardiovascular Diabetol , vol.7 , pp. 34
    • Grijalva, J.1    Hicks, S.2    Zhao, X.3    Medikayala, S.4    Kaminski, P.M.5    Wolm, M.S.6    Edwards, J.G.7
  • 19
    • 68049114316 scopus 로고    scopus 로고
    • Effects of grape seed extract and its ethylacetate/ethanol fraction on blood glucose levels in a model of type 2 diabetes
    • Hwang, I.K., D.W. Kim, J.H. Park, S.S. Lim and K. Y. Yoo et al, 2009. Effects of grape seed extract and its ethylacetate/ethanol fraction on blood glucose levels in a model of type 2 diabetes. Phytother. Res., 23: 1182-1185.
    • (2009) Phytother. Res , vol.23 , pp. 1182-1185
    • Hwang, I.K.1    Kim, D.W.2    Park, J.H.3    Lim, S.S.4    Yoo, K.Y.5
  • 20
    • 33947253955 scopus 로고    scopus 로고
    • Treatment with the xanthine oxidase inhibitor, allopurinol, improves nerve and vascular function in diabetic rats
    • Inkster, M.E., M.A. Cotter and N.E. Cameron, 2007. Treatment with the xanthine oxidase inhibitor, allopurinol, improves nerve and vascular function in diabetic rats. Eur. J. Pharmacol., 561: 63-71.
    • (2007) Eur. J. Pharmacol , vol.561 , pp. 63-71
    • Inkster, M.E.1    Cotter, M.A.2    Cameron, N.E.3
  • 21
    • 0035117742 scopus 로고    scopus 로고
    • Short-term exercise training increases ach-induced relaxation and enos protein in porcine pulmonary arteries
    • Johnson, L.R., J.W. Rush, J.R Turk, E.M. Price and M.H. Laughlin, 2001. Short-term exercise training increases ach-induced relaxation and enos protein in porcine pulmonary arteries. J. Applied Physiol, 90: 1102-1110.
    • (2001) J. Applied Physiol , vol.90 , pp. 1102-1110
    • Johnson, L.R.1    Rush, J.W.2    Turk, J.R.3    Price, E.M.4    Laughlin, M.H.5
  • 22
    • 27944445736 scopus 로고    scopus 로고
    • Mechanisms of endothelial dysfunction with development of type 1 diabetes mellitus: Role of insulin and c-peptide
    • Joshua, I.G., Q. Zhang, J.C. Falcone, A.P. Bratcher, W.E. Rodriguez and S.C. Tyagi, 2005. Mechanisms of endothelial dysfunction with development of type 1 diabetes mellitus: Role of insulin and c-peptide. J. Cellular Biochem., 96: 1149-1156.
    • (2005) J. Cellular Biochem , vol.96 , pp. 1149-1156
    • Joshua, I.G.1    Zhang, Q.2    Falcone, J.C.3    Bratcher, A.P.4    Rodriguez, W.E.5    Tyagi, S.C.6
  • 23
    • 0034683051 scopus 로고    scopus 로고
    • Antioxidants, diabetes and endothelial dysfunction
    • Laight, D.W., M.J. Carrier and E.E. Anggard, 2000. Antioxidants, diabetes and endothelial dysfunction. Cardiovasc. Res., 47: 457-464.
    • (2000) Cardiovasc. Res , vol.47 , pp. 457-464
    • Laight, D.W.1    Carrier, M.J.2    Anggard, E.E.3
  • 24
    • 0029023823 scopus 로고
    • Endothelium-mediated control of coronary vascular tone after chronic exercise training
    • Laughlin, M.H., 1995. Endothelium-mediated control of coronary vascular tone after chronic exercise training. Med. Sci. Sports Exerc, 27: 1135-1144.
    • (1995) Med. Sci. Sports Exerc , vol.27 , pp. 1135-1144
    • Laughlin, M.H.1
  • 25
    • 55349089239 scopus 로고    scopus 로고
    • Cardioprotective actions of grape polyphenols
    • Leifert, W.R. and M.Y. Abeywardena, 2008. Cardioprotective actions of grape polyphenols. Nutr. Res., 28: 729-737.
    • (2008) Nutr. Res , vol.28 , pp. 729-737
    • Leifert, W.R.1    Abeywardena, M.Y.2
  • 26
    • 43449114799 scopus 로고    scopus 로고
    • Back-regulation of six oxidative stress proteins with grape seed proanthocyanidin extracts in rat diabetic nephropathy
    • Li, B. Y., M. Cheng, H.Q. Gao, Y.B. Ma and L. Xu et al., 2008. Back-regulation of six oxidative stress proteins with grape seed proanthocyanidin extracts in rat diabetic nephropathy. J. Cell. Biochem., 104: 668-679.
    • (2008) J. Cell. Biochem , vol.104 , pp. 668-679
    • Li, B.Y.1    Cheng, M.2    Gao, H.Q.3    Ma, Y.B.4    Xu, L.5
  • 27
    • 34249666141 scopus 로고    scopus 로고
    • Quercetin, a flavonoid antioxidant, modulates endothelium-derived nitric oxide bioavailability in diabetic rat aortas
    • Machha, A., F.I. Achike, A.M. Mustafa and M.R. Mustafa, 2007. Quercetin, a flavonoid antioxidant, modulates endothelium-derived nitric oxide bioavailability in diabetic rat aortas. Nitric. Oxide., 16: 442-447.
    • (2007) Nitric. Oxide , vol.16 , pp. 442-447
    • Machha, A.1    Achike, F.I.2    Mustafa, A.M.3    Mustafa, M.R.4
  • 28
    • 33646070557 scopus 로고    scopus 로고
    • Metformin reduces blood pressure and restores endothelial function in aorta of streptozotocin-induced diabetic rats
    • Majithiya, J.B. and R. Balaraman, 2006. Metformin reduces blood pressure and restores endothelial function in aorta of streptozotocin-induced diabetic rats. Life Sci., 78: 2615-2624.
    • (2006) Life Sci , vol.78 , pp. 2615-2624
    • Majithiya, J.B.1    Balaraman, R.2
  • 29
    • 78651170765 scopus 로고
    • The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessels of the rat
    • McGregor, D.D., 1965. The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessels of the rat. J. Physiol, 177: 21-30.
    • (1965) J. Physiol , vol.177 , pp. 21-30
    • McGregor, D.D.1
  • 30
    • 0036223849 scopus 로고    scopus 로고
    • Exercise training improves acetylcho line-induced endothelium-dependent hyperpolarization in type 2 diabetic rats, otsuka long-evans tokushima fatty rats
    • Minami, A., N. Ishimura, N. Harada, S. Sakamoto, Y. Niwa and Y. Nakaya, 2002. Exercise training improves acetylcho line-induced endothelium-dependent hyperpolarization in type 2 diabetic rats, otsuka long-evans tokushima fatty rats. Atherosclerosis, 162: 85-92.
    • (2002) Atherosclerosis , vol.162 , pp. 85-92
    • Minami, A.1    Ishimura, N.2    Harada, N.3    Sakamoto, S.4    Niwa, Y.5    Nakaya, Y.6
  • 31
    • 0030071185 scopus 로고    scopus 로고
    • Fosinopril improves regulation of vascular tone in mesenteric bed of diabetic rats
    • Olbnch, A., P. Rosen, R.D. Hilgers and S. Dhein, 1996. Fosinopril improves regulation of vascular tone in mesenteric bed of diabetic rats. J. Cardiovasc. Pharmacol, 27: 187-194.
    • (1996) J. Cardiovasc. Pharmacol , vol.27 , pp. 187-194
    • Olbnch, A.1    Rosen, P.2    Hilgers, R.D.3    Dhein, S.4
  • 32
    • 29644437686 scopus 로고    scopus 로고
    • The effect of systemic leptin administration on aorta smooth muscle responses in diabetic rats
    • Ozer, C, S. Gulen, E. Dilekoz, A. Babul and Z.S. Ercan, 2006. The effect of systemic leptin administration on aorta smooth muscle responses in diabetic rats. Mol. Cell. Biochem., 282: 187-191.
    • (2006) Mol. Cell. Biochem , vol.282 , pp. 187-191
    • Ozer, C.1    Gulen, S.2    Dilekoz, E.3    Babul, A.4    Ercan, Z.S.5
  • 33
    • 0023713429 scopus 로고
    • Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta
    • Pieper, G.M. and G.J. Gross, 1988. Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta. Am. J. Physiol, 255: H825-H833.
    • (1988) Am. J. Physiol , vol.255
    • Pieper, G.M.1    Gross, G.J.2
  • 35
    • 37849004479 scopus 로고    scopus 로고
    • Systemic adaptation to oxidative challenge induced by regular exercise
    • Radak, Z., H.Y. Chung and S. Goto, 2008. Systemic adaptation to oxidative challenge induced by regular exercise. Free Radical Biol. Med., 44: 153-159.
    • (2008) Free Radical Biol. Med , vol.44 , pp. 153-159
    • Radak, Z.1    Chung, H.Y.2    Goto, S.3
  • 37
    • 0028118896 scopus 로고
    • Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression
    • Sessa, W.C., K. Pritchard, N. Seyedi, J. Wang and T.H. Hintze, 1994. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ. Res., 74: 349-353.
    • (1994) Circ. Res , vol.74 , pp. 349-353
    • Sessa, W.C.1    Pritchard, K.2    Seyedi, N.3    Wang, J.4    Hintze, T.H.5
  • 38
    • 67650064637 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins protect cardiomyocytes from ischemia and reperfusion injury via Akt-NOS signaling
    • Shao, Z.H., K.R. Wojcik, A. Dossumbekova, C. Hsu and S.R. Mehendale et al, 2009. Grape seed proanthocyanidins protect cardiomyocytes from ischemia and reperfusion injury via Akt-NOS signaling. J. Cell. Biochem., 107: 697-705.
    • (2009) J. Cell. Biochem , vol.107 , pp. 697-705
    • Shao, Z.H.1    Wojcik, K.R.2    Dossumbekova, A.3    Hsu, C.4    Mehendale, S.R.5
  • 39
    • 1642559404 scopus 로고    scopus 로고
    • Polyphenolics in grape seed biochemistry and functionality
    • Shi, J., J. Yu, J.E. Pohrly and Y. Kakud, 2003. Polyphenolics in grape seed biochemistry and functionality. J. Med. Food, 6: 291-299.
    • (2003) J. Med. Food , vol.6 , pp. 291-299
    • Shi, J.1    Yu, J.2    Pohrly, J.E.3    Kakud, Y.4
  • 40
    • 0037337890 scopus 로고    scopus 로고
    • Vitamins reverse endothelial dysfunction through regulation of eNOS andNAD(P)H oxidase activities
    • Ulker, S., P.P. McKeown and U. Bayraktutan, 2003. Vitamins reverse endothelial dysfunction through regulation of eNOS andNAD(P)H oxidase activities. Hypertension, 41: 534-539.
    • (2003) Hypertension , vol.41 , pp. 534-539
    • Ulker, S.1    McKeown, P.P.2    Bayraktutan, U.3
  • 41
    • 66949138069 scopus 로고    scopus 로고
    • Anti-diabetic effects of 1 -methylnicotinamide (MNA) in streptozocin-induced diabetes in rats
    • Watala, C, P. Kazmierczak, M. Dobaczewski, T. Przygodzki and M. Bartus et al, 2009. Anti-diabetic effects of 1 -methylnicotinamide (MNA) in streptozocin-induced diabetes in rats. Pharmacol. Rep., 61: 86-98.
    • (2009) Pharmacol. Rep , vol.61 , pp. 86-98
    • Watala, C.1    Kazmierczak, P.2    Dobaczewski, M.3    Przygodzki, T.4    Bartus, M.5
  • 42
    • 67349163186 scopus 로고    scopus 로고
    • 3',4'-dihydroxyflavonol prevents diabetes-induced endothelial dysfunction in rat aorta
    • Woodman, O.L. and W. Malakul, 2009. 3',4'-dihydroxyflavonol prevents diabetes-induced endothelial dysfunction in rat aorta. Life Sci., 85: 54-59.
    • (2009) Life Sci , vol.85 , pp. 54-59
    • Woodman, O.L.1    Malakul, W.2
  • 43
    • 0038648918 scopus 로고    scopus 로고
    • Histamine-induced vasodilatation in the perfused mesenteric arterial bed of diabetic rats
    • Yousif, M.H.M., M.A. Oriowo, A. Cherian and A.S. Adeagbo, 2002. Histamine-induced vasodilatation in the perfused mesenteric arterial bed of diabetic rats. Vascul. Pharmacol., 39: 287-292.
    • (2002) Vascul. Pharmacol , vol.39 , pp. 287-292
    • Yousif, M.H.M.1    Oriowo, M.A.2    Cherian, A.3    Adeagbo, A.S.4
  • 44
    • 52649172042 scopus 로고    scopus 로고
    • Vasorelaxational effects of procyanidins on rabbit aorta in vitro and decreasing arterial blood pressure in vivo
    • Zhang, T.X., C.Q. Niu, J.M. Hu, H. Liuand, H.E. Jing, 2008. Vasorelaxational effects of procyanidins on rabbit aorta in vitro and decreasing arterial blood pressure in vivo. Zhongguo Zhong YaoZaZhi, 33: 1720-1723.
    • (2008) Zhongguo Zhong YaoZaZhi , vol.33 , pp. 1720-1723
    • Zhang, T.X.1    Niu, C.Q.2    Hu, J.M.3    Liuand, H.4    Jing, H.E.5


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