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Volumn 8, Issue 1, 2012, Pages 81-91

Choice of antiepileptic drugs for the elderly: Possible drug interactions and adverse effects

Author keywords

Adverse drug reactions; Antiepileptic drugs; Elderly; Interactions

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CARBAPENEM; CLONAZEPAM; ERTAPENEM; ETIRACETAM; FELBAMATE; GABAPENTIN; HARKOSERIDE; LAMOTRIGINE; LOPINAVIR; MEROPENEM; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PREGABALIN; RITONAVIR; THIAZIDE DIURETIC AGENT; TIAGABINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN;

EID: 84255171153     PISSN: 17425255     EISSN: 17447607     Source Type: Journal    
DOI: 10.1517/17425255.2012.645535     Document Type: Review
Times cited : (39)

References (96)
  • 2
    • 0025119777 scopus 로고
    • National General Practice Study of Epilepsy: Newly diagnosed epileptic seizures in a general population
    • DOI 10.1016/0140-6736(90)92959-L
    • Sander JW, Hart YM, Johnson AL, Shorvon SD. National general practice study of epilepsy: newly diagnosed epileptic seizures in a general population. Lancet 1990;336:1267-71 (Pubitemid 20382979)
    • (1990) Lancet , vol.336 , Issue.8726 , pp. 1267-1271
    • Sander, J.W.A.S.1    Hart, Y.M.2    Johnson, A.L.3    Shorvon, S.D.4
  • 4
    • 80054732003 scopus 로고    scopus 로고
    • Antiepileptic drug use in community-dwelling and institutionalized elderly: A nationwide study of over 1 300 000 older people
    • Epub ahead of print
    • Johnell K, Fastbom J. Antiepileptic drug use in community-dwelling and institutionalized elderly: a nationwide study of over 1 300 000 older people. Eur J Clin Pharmacol 2011; Epub ahead of print
    • (2011) Eur J Clin Pharmacol
    • Johnell, K.1    Fastbom, J.2
  • 5
    • 77949774970 scopus 로고    scopus 로고
    • Recommendations for the prevention of adverse drug reactions in older adults with dementia
    • Gomez-Pavon J, Gonzalez Garcia P, Frances Roman I, et al. Recommendations for the prevention of adverse drug reactions in older adults with dementia. Rev Esp Geriatr Gerontol 2010;45:89-96
    • (2010) Rev Esp Geriatr Gerontol , vol.45 , pp. 89-96
    • Gomez-Pavon, J.1    Gonzalez Garcia, P.2    Frances Roman, I.3
  • 6
    • 65549124065 scopus 로고    scopus 로고
    • Perioperative drug therapy in elderly patients
    • Rivera R, Antognini JF. Perioperative drug therapy in elderly patients. Anesthesiology 2009;110:1176-81
    • (2009) Anesthesiology , vol.110 , pp. 1176-81
    • Rivera, R.1    Antognini, J.F.2
  • 8
    • 77949333671 scopus 로고    scopus 로고
    • Management of new-onset epilepsy in the elderly
    • Arain AM, Abou-Khalil BW. Management of new-onset epilepsy in the elderly. Nat Rev Neurol 2009;5:363-71
    • (2009) Nat Rev Neurol , vol.5 , pp. 363-71
    • Arain, A.M.1    Abou-Khalil, B.W.2
  • 9
    • 33947411319 scopus 로고    scopus 로고
    • Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy
    • DOI 10.1111/j.1464-5491.2007.02093.x
    • Jose VM, Bhansali A, Hota D, Pandhi P. Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy. Diabet Med 2007;24:377-83 (Pubitemid 46452398)
    • (2007) Diabetic Medicine , vol.24 , Issue.4 , pp. 377-383
    • Jose, V.M.1    Bhansali, A.2    Hota, D.3    Pandhi, P.4
  • 11
    • 47049127441 scopus 로고    scopus 로고
    • Epilepsy outcomes in elderly treated with topiramate
    • Stefan H, Hubbertz L, Peglau I, et al. Epilepsy outcomes in elderly treated with topiramate. Acta Neurol Scand 2008;118:164-74
    • (2008) Acta Neurol Scand , vol.118 , pp. 164-74
    • Stefan, H.1    Hubbertz, L.2    Peglau, I.3
  • 12
    • 77955297109 scopus 로고    scopus 로고
    • Review of topiramate for the treatment of epilepsy in elderly patients
    • Sommer BR, Fenn HH. Review of topiramate for the treatment of epilepsy in elderly patients. Clin Interv Aging 2010;5:89-99
    • (2010) Clin Interv Aging , vol.5 , pp. 89-99
    • Sommer, B.R.1    Fenn, H.H.2
  • 13
    • 0032877268 scopus 로고    scopus 로고
    • Multicentre, double-blind, randomised comparison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy
    • DOI 10.1016/S0920-1211(99)00039-X, PII S092012119900039X
    • Brodie MJ, Overstall PW, Giorgi L. Multicentre, double-blind, randomized comparison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy. The UK Lamotrigine Elderly Study Group. Epilepsy Res 1999;37:81-7 (Pubitemid 29413167)
    • (1999) Epilepsy Research , vol.37 , Issue.1 , pp. 81-87
    • Brodie, M.J.1    Overstall, P.W.2    Giorgi, L.3
  • 14
    • 34447319721 scopus 로고    scopus 로고
    • An international multicenter randomized double-blind controlled trial of lamotrigine and sustained-release carbamazepine in the treatment of newly diagnosed epilepsy in the elderly
    • DOI 10.1111/j.1528-1167.2007.01128.x
    • Saetre E, Perucca E, Isojarvi J, et al. An international multicenter randomized double-blind controlled trial of lamotrigine and sustained-release carbamazepine in the treatment of newly diagnosed epilepsy in the elderly. Epilepsia 2007;48:1292-302 (Pubitemid 47063092)
    • (2007) Epilepsia , vol.48 , Issue.7 , pp. 1292-1302
    • Saetre, E.1    Perucca, E.2    Isojarvi, J.3    Gjerstad, L.4
  • 15
    • 0028280090 scopus 로고
    • Hyponatremia associated with carbamazepine and oxcarbazepine therapy: A review
    • Van Amelsvoort T, Bakshi R, Devaux CB, Schwabe S. Hyponatremia associated with carbamazepine and oxcarbazepine therapy: a review. Epilepsia 1994;35:181-8 (Pubitemid 24074484)
    • (1994) Epilepsia , vol.35 , Issue.1 , pp. 181-188
    • Van Amelsvoort, T.1    Bakshi, R.2    Devaux, C.B.3    Schwabe, S.4
  • 17
    • 33749344982 scopus 로고    scopus 로고
    • A case of severe hyponatremia in a patient suffering from epilepsy and using oxcarbazepine
    • Gumbrevicius G, Sveikata A. A case of severe hyponatremia in a patient suffering from epilepsy and using oxcarbazepine. Medicina (Kaunas) 2006;42:649-52
    • (2006) Medicina (Kaunas) , vol.42 , pp. 649-52
    • Gumbrevicius, G.1    Sveikata, A.2
  • 18
    • 46549084628 scopus 로고    scopus 로고
    • Efficacy, tolerability, and side effects of oxcarbazepine monotherapy: A prospective study in adult and elderly patients with newly diagnosed partial epilepsy
    • Dogan EA, Usta BE, Bilgen R, et al. Efficacy, tolerability, and side effects of oxcarbazepine monotherapy: a prospective study in adult and elderly patients with newly diagnosed partial epilepsy. Epilepsy Behav 2008;13:156-61
    • (2008) Epilepsy Behav , vol.13 , pp. 156-61
    • Dogan, E.A.1    Usta, B.E.2    Bilgen, R.3
  • 19
    • 50849132592 scopus 로고    scopus 로고
    • Oxcarbazepine and adverse events: Impact of age, dosage, metabolite serum concentrations and concomitant antiepileptic therapy
    • Ortenzi A, Paggi A, Foschi N, et al. Oxcarbazepine and adverse events: impact of age, dosage, metabolite serum concentrations and concomitant antiepileptic therapy. Funct Neurol 2008;23:97-100
    • (2008) Funct Neurol , vol.23 , pp. 97-100
    • Ortenzi, A.1    Paggi, A.2    Foschi, N.3
  • 20
    • 0037968501 scopus 로고    scopus 로고
    • Safety and tolerability of oxcarbazepine in elderly patients with epilepsy
    • DOI 10.1016/S1525-5050(03)00037-4
    • Kutluay E, McCague K, DSouza J, Beydoun A. Safety and tolerability of oxcarbazepine in elderly patients with epilepsy. Epilepsy Behav 2003;4:175-80 (Pubitemid 37184590)
    • (2003) Epilepsy and Behavior , vol.4 , Issue.2 , pp. 175-180
    • Kutluay, E.1    McCague, K.2    D'Souza, J.3    Beydoun, A.4
  • 21
    • 41349115538 scopus 로고    scopus 로고
    • Oxcarbazepine-induced hemolytic anemia in a geriatric patient
    • DOI 10.1097/MJT.0b013e31815afb6f, PII 0004539120080300000017
    • Chaudhry MM, Abrar M, Mutahir K, Mendoza C. Oxcarbazepine-induced hemolytic anemia in a geriatric patient. Am J Ther 2008;15:187-9 (Pubitemid 351450786)
    • (2008) American Journal of Therapeutics , vol.15 , Issue.2 , pp. 187-189
    • Chaudhry, M.M.1    Abrar, M.2    Mutahir, K.3    Mendoza, C.4
  • 22
    • 29544451720 scopus 로고    scopus 로고
    • Oxcarbazepine-induced thrombocytopenia
    • DOI 10.1176/appi.psy.47.1.73
    • Mahmud J, Mathews M, Verma S, Basil B. Oxcarbazepine-induced thrombocytopenia. Psychosomatics 2006;47:73-4 (Pubitemid 43017125)
    • (2006) Psychosomatics , vol.47 , Issue.1 , pp. 73-74
    • Mahmud, J.1    Mathews, M.2    Verma, S.3    Basil, B.4
  • 23
    • 34547949534 scopus 로고    scopus 로고
    • Assessment of tolerability in elderly patients: Changing to lamotrigine therapy
    • DOI 10.1016/j.amjopharm.2007.06.001, PII S1543594607000244
    • Evans BK, Kustra RP, Hammer AE. Assessment of tolerability in elderly patients: changing to lamotrigine therapy. Am J Geriatr Pharmacother 2007;5:112-19 (Pubitemid 47264114)
    • (2007) American Journal Geriatric Pharmacotherapy , vol.5 , Issue.2 , pp. 112-119
    • Evans, B.K.1    Kustra, R.P.2    Hammer, A.E.3
  • 25
    • 0028330545 scopus 로고
    • Impact of valproate and phenytoin on cognitive function in elderly patients: Results of a single-blind randomized comparative study
    • Craig I, Tallis R. Impact of valproate and phenytoin on cognitive function in elderly patients: results of a single-blind randomized comparative study. Epilepsia 1994;35:381-90 (Pubitemid 24138826)
    • (1994) Epilepsia , vol.35 , Issue.2 , pp. 381-390
    • Craig, I.1    Tallis, R.2
  • 26
    • 0034957749 scopus 로고    scopus 로고
    • Comparative cognitive effects of carbamazepine and gabapentin in healthy senior adults
    • DOI 10.1046/j.1528-1157.2001.33300.x
    • Martin R, Meador K, Turrentine L, et al. Comparative cognitive effects of carbamazepine and gabapentin in healthy senior adults. Epilepsia 2001;42:764-71 (Pubitemid 32605939)
    • (2001) Epilepsia , vol.42 , Issue.6 , pp. 764-771
    • Martin, R.1    Meador, K.2    Turrentine, L.3    Faught, E.4    Sinclair, K.5    Kuzniecky, R.6    Gilliam, F.7
  • 27
    • 76949088300 scopus 로고    scopus 로고
    • Suicide-related behaviors in older patients with new anti epileptic drug use: Data from the VA hospital system
    • VanCott AC, Cramer JA, Copeland LA, et al. Suicide-related behaviors in older patients with new anti epileptic drug use: data from the VA hospital system. BMC Med 2010;8:4
    • (2010) BMC Med , vol.8 , pp. 4
    • Vancott, A.C.1    Cramer, J.A.2    Copeland, L.A.3
  • 28
    • 33847216894 scopus 로고    scopus 로고
    • An association of intrusive, repetitive phrases with lamotrigine treatment in bipolar II disorder
    • Kemp DE, Gilmer WS, Fleck J, Dago PL. An association of intrusive, repetitive phrases with lamotrigine treatment in bipolar II disorder. CNS Spectr 2007;12:106-11
    • (2007) CNS Spectr , vol.12 , pp. 106-11
    • Kemp, D.E.1    Gilmer, W.S.2    Fleck, J.3    Dago, P.L.4
  • 29
    • 0023891943 scopus 로고
    • Cardiopulmonary arrest following intravenous phenytoin loading
    • York RC, Coleridge ST. Cardiopulmonary arrest following intravenous phenytoin loading. Am J Emerg Med 1988;6:255-9
    • (1988) Am J Emerg Med , vol.6 , pp. 255-9
    • York, R.C.1    Coleridge, S.T.2
  • 30
    • 0025837105 scopus 로고
    • A case of propylene glycol toxic reaction associated with etomidate infusion
    • Bedichek E, Kirschbaum B. A case of propylene glycol toxic reaction associated with etomidate infusion. Arch Intern Med 1991;151:2297-8
    • (1991) Arch Intern Med , vol.151 , pp. 2297-8
    • Bedichek, E.1    Kirschbaum, B.2
  • 31
    • 31144477275 scopus 로고    scopus 로고
    • Fosphenytoin may cause hemodynamically unstable bradydysrhythmias
    • DOI 10.1016/j.jemermed.2005.01.034, PII S0736467905003756
    • Adams BD, Buckley NH, Kim JY, Tipps LB. Fosphenytoin may cause hemodynamically unstable bradydysrhythmias. J Emerg Med 2006;30:75-9 (Pubitemid 43129882)
    • (2006) Journal of Emergency Medicine , vol.30 , Issue.1 , pp. 75-79
    • Adams, B.D.1    Buckley, N.H.2    Kim, J.Y.3    Tipps, L.B.4
  • 32
    • 77952653328 scopus 로고    scopus 로고
    • Intravenous levetiracetam as first-line treatment of status epilepticus in the elderly
    • Fattouch J, Di Bonaventura C, Casciato S, et al. Intravenous levetiracetam as first-line treatment of status epilepticus in the elderly. Acta Neurol Scand 2010; 121:418-21
    • (2010) Acta Neurol Scand , vol.121 , pp. 418-21
    • Fattouch, J.1    Di Bonaventura, C.2    Casciato, S.3
  • 33
    • 79959949279 scopus 로고    scopus 로고
    • Second-line status epilepticus treatment: Comparison of phenytoin, valproate, and levetiracetam
    • Alvarez V, Januel JM, Burnand B, Rossetti AO. Second-line status epilepticus treatment: Comparison of phenytoin, valproate, and levetiracetam. Epilepsia 2011;52:1292-6
    • (2011) Epilepsia , vol.52 , pp. 1292-6
    • Alvarez, V.1    Januel, J.M.2    Burnand, B.3    Rossetti, A.O.4
  • 34
    • 80053575364 scopus 로고    scopus 로고
    • Intravenous lacosamide in status epilepticus and seizure clusters
    • Epub ahead of print
    • Hofler J, Unterberger I, Dobesberger J, et al. Intravenous lacosamide in status epilepticus and seizure clusters. Epilepsia 2011; Epub ahead of print
    • (2011) Epilepsia
    • Hofler, J.1    Unterberger, I.2    Dobesberger, J.3
  • 35
    • 79957475750 scopus 로고    scopus 로고
    • Possible heart failure associated with pregabalin use: Case report
    • Erdogan G, Ceyhan D, Gulec S. Possible heart failure associated with pregabalin use: case report. Agri 2011;23:80-3
    • (2011) Agri , vol.23 , pp. 80-3
    • Erdogan, G.1    Ceyhan, D.2    Gulec, S.3
  • 36
    • 55249086325 scopus 로고    scopus 로고
    • Possible heart failure exacerbation associated with pregabalin: Case discussion and literature review
    • Page RL II, Cantu M, Lindenfeld J, et al. Possible heart failure exacerbation associated with pregabalin: case discussion and literature review. J Cardiovasc Med (Hagerstown) 2008;9:922-5
    • (2008) J Cardiovasc Med (Hagerstown) , vol.9 , pp. 922-5
    • Page, R.L.I.I.1    Cantu, M.2    Lindenfeld, J.3
  • 39
    • 78651339196 scopus 로고    scopus 로고
    • Association of antiepileptic drugs with nontraumatic fractures: A population-based analysis
    • Jette N, Lix LM, Metge CJ, et al. Association of antiepileptic drugs with nontraumatic fractures: a population-based analysis. Arch Neurol 2011;68:107-12
    • (2011) Arch Neurol , vol.68 , pp. 107-12
    • Jette, N.1    Lix, L.M.2    Metge, C.J.3
  • 40
    • 0034840412 scopus 로고    scopus 로고
    • Adverse effects of antiepileptic drugs on bone structure: Epidemiology, mechanisms and therapeutic implications
    • Pack AM, Morrell MJ. Adverse effects of antiepileptic drugs on bone structure: epidemiology, mechanisms and therapeutic implications. CNS Drugs 2001;15:633-42 (Pubitemid 32848344)
    • (2001) CNS Drugs , vol.15 , Issue.8 , pp. 633-642
    • Pack, A.M.1    Morrell, M.J.2
  • 41
    • 80053566974 scopus 로고    scopus 로고
    • The effect of topiramate monotherapy on bone mineral density and markers of bone and mineral metabolism in premenopausal women with epilepsy
    • Heo K, Rhee Y, Lee HW, et al. The effect of topiramate monotherapy on bone mineral density and markers of bone and mineral metabolism in premenopausal women with epilepsy. Epilepsia 2011;52:1884-9
    • (2011) Epilepsia , vol.52 , pp. 1884-9
    • Heo, K.1    Rhee, Y.2    Lee, H.W.3
  • 42
    • 33646671744 scopus 로고    scopus 로고
    • Use of antiepileptic drugs and risk of fractures: Case-control study among patients with epilepsy
    • DOI 10.1212/01.wnl.0000210503.89488.88, PII 0000611420060509000009
    • Souverein PC, Webb DJ, Weil JG, et al. Use of antiepileptic drugs and risk of fractures: case-control study among patients with epilepsy. Neurology 2006;66:1318-24 (Pubitemid 43739637)
    • (2006) Neurology , vol.66 , Issue.9 , pp. 1318-1324
    • Souverein, P.C.1    Webb, D.J.2    Weil, J.G.3    Van Staa, T.P.4    Egberts, A.C.G.5
  • 45
    • 33747079280 scopus 로고    scopus 로고
    • Measuring the effects of antiepileptic medications on balance in older people
    • DOI 10.1016/j.eplepsyres.2006.03.004, PII S092012110600091X
    • Fife TD, Blum D, Fisher RS. Measuring the effects of antiepileptic medications on balance in older people. Epilepsy Res 2006;70:103-9 (Pubitemid 44209223)
    • (2006) Epilepsy Research , vol.70 , Issue.2-3 , pp. 103-109
    • Fife, T.D.1    Blum, D.2    Fisher, R.S.3
  • 46
    • 0031440072 scopus 로고    scopus 로고
    • Evaluation of case reports of aplastic anemia among patients treated with Felbamate
    • DOI 10.1111/j.1528-1157.1997.tb00062.x
    • Kaufman DW, Kelly JP, Anderson T, et al. Evaluation of case reports of aplastic anemia among patients treated with felbamate. Epilepsia 1997;38:1265-9 (Pubitemid 28007514)
    • (1997) Epilepsia , vol.38 , Issue.12 , pp. 1265-1269
    • Kaufman, D.W.1    Kelly, J.P.2    Anderson, T.3    Harmon, D.C.4    Shapiro, S.5
  • 48
    • 0028148392 scopus 로고
    • No authors listed Acute liver failure linked to felbamate use
    • No authors listed Acute liver failure linked to felbamate use. Am J Hosp Pharm 1994;51:2882-7
    • (1994) Am J Hosp Pharm , vol.51 , pp. 2882-7
  • 49
    • 0031787340 scopus 로고    scopus 로고
    • Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs
    • DOI 10.1111/j.1528-1157.1998.tb01679.x
    • Leeder JS. Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs. Epilepsia 1998;39(Suppl 7):S8-16 (Pubitemid 28485582)
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 7
    • Leeder, J.S.1
  • 50
    • 77949362520 scopus 로고    scopus 로고
    • Choice of initial antiepileptic drug for older veterans: Possible pharmacokinetic drug interactions with existing medications
    • Pugh MJ, Vancott AC, Steinman MA, et al. Choice of initial antiepileptic drug for older veterans: possible pharmacokinetic drug interactions with existing medications. Am Geriatr Soc 2010;58:465-71
    • (2010) Am Geriatr Soc , vol.58 , pp. 465-71
    • Pugh, M.J.1    Vancott, A.C.2    Steinman, M.A.3
  • 52
    • 2942597785 scopus 로고    scopus 로고
    • Delirium from valproic acid with lamotrigine
    • Mueller TH, Beeber AR. Delirium from valproic acid with lamotrigine. Am J Psychiatry 2004;161:1128-9
    • (2004) Am J Psychiatry , vol.161 , pp. 1128-9
    • Mueller, T.H.1    Beeber, A.R.2
  • 53
    • 0029759838 scopus 로고    scopus 로고
    • Serum concentrations of lamotrigine in epileptic patients: The influence of dose and comedication
    • DOI 10.1097/00007691-199610000-00001
    • May TW, Rambeck B, Jurgens U. Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication. Ther Drug Monit 1996;18:523-31 (Pubitemid 26330471)
    • (1996) Therapeutic Drug Monitoring , vol.18 , Issue.5 , pp. 523-531
    • May, T.W.1    Rambeck, B.2    Jurgens, U.3
  • 55
    • 0033837480 scopus 로고    scopus 로고
    • Adding valproate to lamotrigine: A study of their pharmacokinetic interaction
    • Kanner AM, Frey M. Adding valproate to lamotrigine: a study of their pharmacokinetic interaction. Neurology 2000;55:588-91 (Pubitemid 30647265)
    • (2000) Neurology , vol.55 , Issue.4 , pp. 588-591
    • Kanner, A.M.1    Frey, M.2
  • 57
    • 0024533595 scopus 로고
    • Effect of felbamate on phenytoin and carbamazepine serum concentrations
    • Graves NM, Holmes GB, Fuerst RH, Leppik IE. Effect of felbamate on phenytoin and carbamazepine serum concentrations. Epilepsia 1989;30:225-9 (Pubitemid 19095114)
    • (1989) Epilepsia , vol.30 , Issue.2 , pp. 225-229
    • Graves, N.M.1    Holmes, G.B.2    Fuerst, R.H.3    Leppik, I.E.4
  • 58
    • 0032805398 scopus 로고    scopus 로고
    • Coadministration of phenytoin and felbamate: Evidence of additional phenytoin dose-reduction requirements based on pharmacokinetics and tolerability with increasing doses of felbamate
    • DOI 10.1111/j.1528-1157.1999.tb00829.x
    • Sachdeo R, Wagner ML, Sachdeo S, et al. Coadministration of phenytoin and felbamate: evidence of additional phenytoin dose-reduction requirements based on pharmacokinetics and tolerability with increasing doses of felbamate. Epilepsia 1999;40:1122-8 (Pubitemid 29372628)
    • (1999) Epilepsia , vol.40 , Issue.8 , pp. 1122-1128
    • Sachdeo, R.1    Wagner, M.L.2    Sachdeo, S.3    Shumaker, R.C.4    Lyness, W.H.5    Rosenberg, A.6    Ward, D.7    Perhach, J.L.8
  • 59
    • 0029845689 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy
    • Sachdeo RC, Sachdeo SK, Walker SA, et al. Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy. Epilepsia 1996;37:774-80 (Pubitemid 26276948)
    • (1996) Epilepsia , vol.37 , Issue.8 , pp. 774-780
    • Sachdeo, R.C.1    Sachdeo, S.K.2    Walker, S.A.3    Kramer, L.D.4    Nayak, R.K.5    Doose, D.R.6
  • 60
    • 0036797057 scopus 로고    scopus 로고
    • Interaction of topiramate with carbamazepine: Two case reports and a review of clinical experience
    • DOI 10.1053/seiz.2001.0633
    • Mack CJ, Kuc S, Mulcrone SA, et al. Interaction of topiramate with carbamazepine: two case reports and a review of clinical experience. Seizure 2002;11:464-7 (Pubitemid 35203595)
    • (2002) Seizure , vol.11 , Issue.7 , pp. 464-467
    • Mack, C.J.1    Kuc, S.2    Mulcrone, S.A.3    Pilley, A.4    Grunewald, R.A.5
  • 61
    • 70449553615 scopus 로고    scopus 로고
    • The influence of drug-drug interaction and patients characteristics on valproic acids clearance in adults with epilepsy using nonlinear mixed effects modeling
    • Vucicevic K, Miljkovic B, Pokrajac M, et al. The influence of drug-drug interaction and patients characteristics on valproic acids clearance in adults with epilepsy using nonlinear mixed effects modeling. Eur J Pharm Sci 2009;38:512-18
    • (2009) Eur J Pharm Sci , vol.38 , pp. 512-18
    • Vucicevic, K.1    Miljkovic, B.2    Pokrajac, M.3
  • 62
    • 52049106877 scopus 로고    scopus 로고
    • Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy
    • Knudsen JF, Sokol GH, Flowers CM. Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy. J Clin Pharm Ther 2008;33:513-19
    • (2008) J Clin Pharm Ther , vol.33 , pp. 513-19
    • Knudsen, J.F.1    Sokol, G.H.2    Flowers, C.M.3
  • 63
  • 64
    • 61549103148 scopus 로고    scopus 로고
    • Effect of concomitant administration of meropenem and valproic acid in an elderly Chinese patient
    • Gu J, Huang Y. Effect of concomitant administration of meropenem and valproic acid in an elderly Chinese patient. Am J Geriatr Pharmacother 2009;7:26-33
    • (2009) Am J Geriatr Pharmacother , vol.7 , pp. 26-33
    • Gu, J.1    Huang, Y.2
  • 65
    • 33745941931 scopus 로고    scopus 로고
    • Epileptic seizures caused by low valproic acid levels from an interaction with meropenem
    • DOI 10.1111/j.1365-2710.2006.00743.x
    • Fudio S, Carcas A, Pinana E, Ortega R. Epileptic seizures caused by low valproic acid levels from an interaction with meropenem. J Clin Pharm Ther 2006;31:393-6 (Pubitemid 44060205)
    • (2006) Journal of Clinical Pharmacy and Therapeutics , vol.31 , Issue.4 , pp. 393-396
    • Fudio, S.1    Carcas, A.2    Pinana, E.3    Ortega, R.4
  • 67
    • 19444366567 scopus 로고    scopus 로고
    • Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: A pooled analysis of data from randomized clinical trials
    • DOI 10.1016/j.eplepsyres.2005.01.005, PII S0920121105000252
    • Gidal BE, Baltes E, Otoul C, Perucca E. Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: a pooled analysis of data from randomized clinical trials. Epilepsy Res 2005;64:1-11 (Pubitemid 40726160)
    • (2005) Epilepsy Research , vol.64 , Issue.1-2 , pp. 1-11
    • Gidal, B.E.1    Baltes, E.2    Otoul, C.3    Perucca, E.4
  • 68
    • 0037322794 scopus 로고    scopus 로고
    • Levetiracetam, a new antiepileptic agent: Lack of in vitro and in vivo pharmacokinetic interaction with valproic acid
    • DOI 10.1046/j.1528-1157.2003.25302.x
    • Coupez R, Nicolas JM, Browne TR. Levetiracetam, a new antiepileptic agent: lack of in vitro and in vivo pharmacokinetic interaction with valproic acid. Epilepsia 2003;44:171-8 (Pubitemid 36206018)
    • (2003) Epilepsia , vol.44 , Issue.2 , pp. 171-178
    • Coupez, R.1    Nicolas, J.-M.2    Browne, T.R.3
  • 71
  • 72
    • 7044260583 scopus 로고    scopus 로고
    • Carbamazepine pharmacokinetics are not affected by zonisamide: In vitro mechanistic study and in vivo clinical study in epileptic patients
    • DOI 10.1016/j.eplepsyres.2004.06.008, PII S0920121104001470
    • Ragueneau-Majlessi I, Levy RH, Bergen D, et al. Carbamazepine pharmacokinetics are not affected by zonisamide: in vitro mechanistic study and in vivo clinical study in epileptic patients. Epilepsy Res 2004;62:1-11 (Pubitemid 39424186)
    • (2004) Epilepsy Research , vol.62 , Issue.1 , pp. 1-11
    • Ragueneau-Majlessi, I.1    Levy, R.H.2    Bergen, D.3    Garnett, W.4    Rosenfeld, W.5    Mather, G.6    Shah, J.7    Grundy, J.S.8
  • 74
    • 26944476349 scopus 로고    scopus 로고
    • Pregabalin drug interaction studies: Lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy
    • Brodie MJ, Wilson EA, Wesche DL, et al. Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy. Epilepsia 2005;46:1407-13
    • (2005) Epilepsia , vol.46 , pp. 1407-13
    • Brodie, M.J.1    Wilson, E.A.2    Wesche, D.L.3
  • 75
    • 77749279921 scopus 로고    scopus 로고
    • Pharmacokinetic interaction study between eslicarbazepine acetate and lamotrigine in healthy subjects
    • Almeida L, Nunes T, Sicard E, et al. Pharmacokinetic interaction study between eslicarbazepine acetate and lamotrigine in healthy subjects. Acta Neurol Scand 2010;121:257-64
    • (2010) Acta Neurol Scand , vol.121 , pp. 257-64
    • Almeida, L.1    Nunes, T.2    Sicard, E.3
  • 76
    • 77952477242 scopus 로고    scopus 로고
    • Pharmacokinetic interaction study between eslicarbazepine acetate and topiramate in healthy subjects
    • Nunes T, Sicard E, Almeida L, et al. Pharmacokinetic interaction study between eslicarbazepine acetate and topiramate in healthy subjects. Curr Med Res Opin 2010;26:1355-62
    • (2010) Curr Med Res Opin , vol.26 , pp. 1355-62
    • Nunes, T.1    Sicard, E.2    Almeida, L.3
  • 77
    • 34248660396 scopus 로고    scopus 로고
    • Epilepsy in the elderly: Special pharmacotherapeutic considerations
    • Gidal B, Anderson G. Epilepsy in the elderly: special pharmacotherapeutic considerations. Consult Pharm 1998;1:62-74
    • (1998) Consult Pharm , vol.1 , pp. 62-74
    • Gidal, B.1    Anderson, G.2
  • 79
    • 0037282719 scopus 로고    scopus 로고
    • Drug treatment of epilepsy in elderly people: Focus on valproic acid
    • DOI 10.2165/00002512-200320020-00005
    • Stephen LJ. Drug treatment of epilepsy in elderly people: focus on valproic acid. Drugs Aging 2003;20:141-52 (Pubitemid 36246296)
    • (2003) Drugs and Aging , vol.20 , Issue.2 , pp. 141-152
    • Stephen, L.J.1
  • 81
    • 1542346294 scopus 로고    scopus 로고
    • Special considerations in treating the elderly patient with epilepsy
    • Ramsay RE, Rowan AJ, Pryor FM. Special considerations in treating the elderly patient with epilepsy. Neurology 2004;62(5 Suppl 2):S24-9 (Pubitemid 38298935)
    • (2004) Neurology , vol.62 , Issue.5 SUPPL. 2
    • Ramsay, R.E.1    Rowan, A.J.2    Pryor, F.M.3
  • 84
    • 0036193577 scopus 로고    scopus 로고
    • Strategies for optimizing antiepileptic drug therapy in elderly people
    • Lackner TE. Strategies for optimizing antiepileptic drug therapy in elderly people. Pharmacotherapy 2002;22:329-64 (Pubitemid 34205171)
    • (2002) Pharmacotherapy , vol.22 , Issue.3 , pp. 329-364
    • Lackner, T.E.1
  • 86
    • 71849110726 scopus 로고    scopus 로고
    • Population pharmacokinetics of lamotrigine in patients with epilepsy
    • Milovanovic JR, Jankovic SM. Population pharmacokinetics of lamotrigine in patients with epilepsy. Int J Clin Pharmacol Ther 2009;47:752-60
    • (2009) Int J Clin Pharmacol Ther , vol.47 , pp. 752-60
    • Milovanovic, J.R.1    Jankovic, S.M.2
  • 87
    • 36549070787 scopus 로고    scopus 로고
    • Serum concentrations of pregabalin in patients with epilepsy: The influence of dose, age, and comedication
    • DOI 10.1097/FTD.0b013e31815d0cd5, PII 0000769120071200000011
    • May TW, Rambeck B, Neb R, Jurgens U. Serum concentrations of pregabalin in patients with epilepsy: the influence of dose, age, and comedication. Ther Drug Monit 2007;29:789-94 (Pubitemid 350190856)
    • (2007) Therapeutic Drug Monitoring , vol.29 , Issue.6 , pp. 789-794
    • May, T.W.1    Rambeck, B.2    Neb, R.3    Jurgens, U.4
  • 89
    • 0025835171 scopus 로고
    • Comparison of lamotrigine pharmacokinetics in young and elderly healthy volunteers
    • Posner J, Holdich T, Chrome P. Comparison of lamotrigine pharmacokinetics in young and elderly healthy volunteers. J Pharm Med 1991;1:121-8
    • (1991) J Pharm Med , vol.1 , pp. 121-8
    • Posner, J.1    Holdich, T.2    Chrome, P.3
  • 90
    • 0027179598 scopus 로고
    • Lamotrigine - A review of its pharmacological properties and clinical efficacy in epilepsy
    • Goa KL, Ross SR, Chrisp P. Lamotrigine: a review of its pharmacological properties and clinical efficacy in epilepsy. Drugs 1993;46:152-76 (Pubitemid 23232410)
    • (1993) Drugs , vol.46 , Issue.1 , pp. 152-176
    • Goa, K.L.1    Ross, S.R.2    Chrisp, P.3
  • 91
    • 0002368328 scopus 로고    scopus 로고
    • Comparative single-dose pharmacokinetics of topiramate in elderly versus young men and women
    • Doose DR, Larsson KL, Natarajan J, et al. Comparative single-dose pharmacokinetics of topiramate in elderly versus young men and women. Epilepsia 1998;39(Suppl 6):56
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 56
    • Doose, D.R.1    Larsson, K.L.2    Natarajan, J.3
  • 92
    • 80051666841 scopus 로고    scopus 로고
    • Treatment of epilepsy to optimize bone health
    • Pack AM. Treatment of epilepsy to optimize bone health. Curr Treat Options Neurol 2011;13:346-54
    • (2011) Curr Treat Options Neurol , vol.13 , pp. 346-54
    • Pack, A.M.1
  • 93
    • 0036074626 scopus 로고    scopus 로고
    • Some common issues in the use of antiepileptic drugs
    • Asconape JJ. Some common issues in the use of antiepileptic drugs. Semin Neurol 2002;22:27-39 (Pubitemid 34792768)
    • (2002) Seminars in Neurology , vol.22 , Issue.1 , pp. 27-39
    • Asconape, J.J.1
  • 94
    • 0038714895 scopus 로고    scopus 로고
    • Clinically important drug interactions in epilepsy: Interactions between antiepileptic drugs and other drugs
    • DOI 10.1016/S1474-4422(03)00483-6
    • Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs. Lancet Neurol 2003;2:473-81 (Pubitemid 36876104)
    • (2003) Lancet Neurology , vol.2 , Issue.8 , pp. 473-481
    • Patsalos, P.N.1    Perucca, E.2


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