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Volumn 26, Issue 2, 2012, Pages 139-148

Level of double negative T cells, which produce TGF-β and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection

Author keywords

double negative T cells; immune activation; primary acute HIV infection; regulatory T cells; transforming growth factor

Indexed keywords

CD38 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 7 RECEPTOR; KI 67 ANTIGEN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84155163937     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32834e1484     Document Type: Article
Times cited : (50)

References (48)
  • 2
    • 0041327667 scopus 로고    scopus 로고
    • Persistent immune activation in HIV-1 infection is associated with progression to AIDS
    • Hazenberg MD, Otto SA, van Benthem BH, Roos MT, Coutinho RA, Lange JM, et al. Persistent immune activation in HIV-1 infection is associated with progression to AIDS. AIDS 2003; 17:1881-1888.
    • (2003) AIDS , vol.17 , pp. 1881-1888
    • Hazenberg, M.D.1    Otto, S.A.2    Van Benthem, B.H.3    Roos, M.T.4    Coutinho, R.A.5    Lange, J.M.6
  • 3
    • 38549149823 scopus 로고    scopus 로고
    • Immune activation and inflammation in HIV-1 infection: Causes and consequences
    • Appay V, Sauce D. Immune activation and inflammation in HIV-1 infection: causes and consequences. J Pathol 2008; 214:231-241.
    • (2008) J Pathol , vol.214 , pp. 231-241
    • Appay, V.1    Sauce, D.2
  • 4
    • 3843056825 scopus 로고    scopus 로고
    • Immune activation set point during early HIV infection predicts subsequent CD4R T-cell changes independent of viral load
    • Deeks SG, Kitchen CM, Liu L, Guo H, Gascon R, Narvaez AB, et al. Immune activation set point during early HIV infection predicts subsequent CD4R T-cell changes independent of viral load. Blood 2004; 104:942-947.
    • (2004) Blood , vol.104 , pp. 942-947
    • Deeks, S.G.1    Kitchen, C.M.2    Liu, L.3    Guo, H.4    Gascon, R.5    Narvaez, A.B.6
  • 5
    • 67649138829 scopus 로고    scopus 로고
    • Regulatory T cells in the control of host-microorganism interactions
    • Belkaid Y, Tarbell K. Regulatory T cells in the control of host-microorganism interactions. Annu Rev Immunol 2009; 27:551-589.
    • (2009) Annu Rev Immunol , vol.27 , pp. 551-589
    • Belkaid, Y.1    Tarbell, K.2
  • 6
    • 33746383248 scopus 로고    scopus 로고
    • Regulatory T cells in virus infections
    • Rouse BT, Sarangi PP, Suvas S. Regulatory T cells in virus infections. Immunol Rev 2006; 212:272-286.
    • (2006) Immunol Rev , vol.212 , pp. 272-286
    • Rouse, B.T.1    Sarangi, P.P.2    Suvas, S.3
  • 7
    • 8644280556 scopus 로고    scopus 로고
    • Human immunodeficiency virus-driven expansion of CD4RCD25R regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
    • Weiss L, Donkova-Petrini V, Caccavelli L, Balbo M, Carbonneil C, Levy Y. Human immunodeficiency virus-driven expansion of CD4RCD25R regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 2004; 104:3249-3256.
    • (2004) Blood , vol.104 , pp. 3249-3256
    • Weiss, L.1    Donkova-Petrini, V.2    Caccavelli, L.3    Balbo, M.4    Carbonneil, C.5    Levy, Y.6
  • 8
    • 3543098686 scopus 로고    scopus 로고
    • CD25RCD4R regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4R and CD8R HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
    • Kinter AL, Hennessey M, Bell A, Kern S, Lin Y, Daucher M, et al. CD25RCD4R regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4R and CD8R HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med 2004; 200:331-343.
    • (2004) J Exp Med , vol.200 , pp. 331-343
    • Kinter, A.L.1    Hennessey, M.2    Bell, A.3    Kern, S.4    Lin, Y.5    Daucher, M.6
  • 9
    • 33144476838 scopus 로고    scopus 로고
    • Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection
    • Estes JD, Li Q, Reynolds MR, Wietgrefe S, Duan L, Schacker T, et al. Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. J Infect Dis 2006; 193:703-712.
    • (2006) J Infect Dis , vol.193 , pp. 703-712
    • Estes, J.D.1    Li, Q.2    Reynolds, M.R.3    Wietgrefe, S.4    Duan, L.5    Schacker, T.6
  • 10
    • 33750320502 scopus 로고    scopus 로고
    • Mucosal but not peripheral FOXP3R regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART
    • Epple HJ, Loddenkemper C, Kunkel D, Troger H, Maul J, Moos V, et al. Mucosal but not peripheral FOXP3R regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART. Blood 2006; 108:3072-3078.
    • (2006) Blood , vol.108 , pp. 3072-3078
    • Epple, H.J.1    Loddenkemper, C.2    Kunkel, D.3    Troger, H.4    Maul, J.5    Moos, V.6
  • 11
    • 20644434609 scopus 로고    scopus 로고
    • Relationship of CD4RCD25R regulatory T cells to immune status in HIV-infected patients
    • Tsunemi S, Iwasaki T, Imado T, Higasa S, Kakishita E, Shirasaka T, et al. Relationship of CD4RCD25R regulatory T cells to immune status in HIV-infected patients. Aids 2005; 19:879-886.
    • (2005) Aids , vol.19 , pp. 879-886
    • Tsunemi, S.1    Iwasaki, T.2    Imado, T.3    Higasa, S.4    Kakishita, E.5    Shirasaka, T.6
  • 12
    • 15444363618 scopus 로고    scopus 로고
    • Depletion of regulatory T cells in HIV infection is associated with immune activation
    • Eggena MP, Barugahare B, Jones N, Okello M, Mutalya S, Kityo C, et al. Depletion of regulatory T cells in HIV infection is associated with immune activation. J Immunol 2005; 174: 4407-4414.
    • (2005) J Immunol , vol.174 , pp. 4407-4414
    • Eggena, M.P.1    Barugahare, B.2    Jones, N.3    Okello, M.4    Mutalya, S.5    Kityo, C.6
  • 13
    • 38949128315 scopus 로고    scopus 로고
    • FOXP3 expressing CD127lo CD4R T cells inversely correlate with CD38R CD8R T cell activation levels in primary HIV-1 infection
    • Ndhlovu LC, Loo CP, Spotts G, Nixon DF, Hecht FM. FOXP3 expressing CD127lo CD4R T cells inversely correlate with CD38R CD8R T cell activation levels in primary HIV-1 infection. J Leukoc Biol 2008; 83:254-262.
    • (2008) J Leukoc Biol , vol.83 , pp. 254-262
    • Ndhlovu, L.C.1    Loo, C.P.2    Spotts, G.3    Nixon, D.F.4    Hecht, F.M.5
  • 14
    • 34447578626 scopus 로고    scopus 로고
    • Proportions of circulating T cells with a regulatory cell phenotype increase with HIV-associated immune activation and remain high on antiretroviral therapy
    • Lim A, Tan D, Price P, Kamarulzaman A, Tan HY, James I, et al. Proportions of circulating T cells with a regulatory cell phenotype increase with HIV-associated immune activation and remain high on antiretroviral therapy. Aids 2007; 21: 1525-1534.
    • (2007) Aids , vol.21 , pp. 1525-1534
    • Lim, A.1    Tan, D.2    Price, P.3    Kamarulzaman, A.4    Tan, H.Y.5    James, I.6
  • 15
    • 77955351656 scopus 로고    scopus 로고
    • Relationship between regulatory T cells and immune activation in human immunodeficiency virus-infected patients interrupting antiretroviral therapy
    • Weiss L, Piketty C, Assoumou L, Didier C, Caccavelli L, Donkova-Petrini V, et al. Relationship between regulatory T cells and immune activation in human immunodeficiency virus-infected patients interrupting antiretroviral therapy. PLoS One 2010; 5:e11659.
    • (2010) PLoS One , vol.5
    • Weiss, L.1    Piketty, C.2    Assoumou, L.3    Didier, C.4    Caccavelli, L.5    Donkova-Petrini, V.6
  • 16
    • 57349175888 scopus 로고    scopus 로고
    • HIV-specific regulatory T cells are associated with higher CD4 cell counts in primary infection
    • Kared H, Lelievre JD, Donkova-Petrini V, Aouba A, Melica G, Balbo M, et al. HIV-specific regulatory T cells are associated with higher CD4 cell counts in primary infection. AIDS 2008; 22:2451-2460.
    • (2008) AIDS , vol.22 , pp. 2451-2460
    • Kared, H.1    Lelievre, J.D.2    Donkova-Petrini, V.3    Aouba, A.4    Melica, G.5    Balbo, M.6
  • 17
    • 37049026246 scopus 로고    scopus 로고
    • FoxP3RCD25RCD8RT-cell induction during primary simian immunodeficiency virus infection in cynomolgus macaques correlates with low CD4R T-cell activation and high viral load
    • Karlsson I, Malleret B, Brochard P, Delache B, Calvo J, Le Grand R, et al. FoxP3RCD25RCD8RT-cell induction during primary simian immunodeficiency virus infection in cynomolgus macaques correlates with low CD4R T-cell activation and high viral load. J Virol 2007; 81:13444-13455.
    • (2007) J Virol , vol.81 , pp. 13444-13455
    • Karlsson, I.1    Malleret, B.2    Brochard, P.3    Delache, B.4    Calvo, J.5    Le Grand, R.6
  • 18
    • 45549107134 scopus 로고    scopus 로고
    • Revival of CD8R Treg-mediated suppression
    • Smith TR, Kumar V. Revival of CD8R Treg-mediated suppression. Trends Immunol 2008; 29:337-342.
    • (2008) Trends Immunol , vol.29 , pp. 337-342
    • Smith, T.R.1    Kumar, V.2
  • 19
    • 0033929005 scopus 로고    scopus 로고
    • Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression
    • Zhang ZX, Yang L, Young KJ, DuTemple B, Zhang L. Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression. Nat Med 2000; 6:782-789.
    • (2000) Nat Med , vol.6 , pp. 782-789
    • Zhang, Z.X.1    Yang, L.2    Young, K.J.3    Dutemple, B.4    Zhang, L.5
  • 20
    • 20144388310 scopus 로고    scopus 로고
    • Isolation and characterization of human antigen-specific TCR alpha betaR CD4(S)CD8S doublenegative regulatory T cells
    • Fischer K, Voelkl S, Heymann J, Przybylski GK, Mondal K, Laumer M, et al. Isolation and characterization of human antigen-specific TCR alpha betaR CD4(S)CD8S doublenegative regulatory T cells. Blood 2005; 105:2828-2835.
    • (2005) Blood , vol.105 , pp. 2828-2835
    • Fischer, K.1    Voelkl, S.2    Heymann, J.3    Przybylski, G.K.4    Mondal, K.5    Laumer, M.6
  • 21
    • 77952580564 scopus 로고    scopus 로고
    • Despite being highly diverse, immunovirological status strongly correlates with clinical symptoms during primary HIV-1 infection: A cross-sectional study based on 674 patients enrolled in the ANRS CO 06 PRIMO cohort
    • Ghosn J, Deveau C, Chaix ML, Goujard C, Galimand J, Zitoun Y, et al. Despite being highly diverse, immunovirological status strongly correlates with clinical symptoms during primary HIV-1 infection: a cross-sectional study based on 674 patients enrolled in the ANRS CO 06 PRIMO cohort. J Antimicrob Chemother 2010; 65:741-748.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 741-748
    • Ghosn, J.1    Deveau, C.2    Chaix, M.L.3    Goujard, C.4    Galimand, J.5    Zitoun, Y.6
  • 22
    • 33750310898 scopus 로고    scopus 로고
    • HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS
    • Nilsson J, Boasso A, Velilla PA, Zhang R, Vaccari M, Franchini G, et al. HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood 2006; 108:3808-3817.
    • (2006) Blood , vol.108 , pp. 3808-3817
    • Nilsson, J.1    Boasso, A.2    Velilla, P.A.3    Zhang, R.4    Vaccari, M.5    Franchini, G.6
  • 23
    • 79952123612 scopus 로고    scopus 로고
    • Partial regulatory T cell depletion prior to acute feline immunodeficiency virus infection does not alter disease pathogenesis
    • Mikkelsen SR, Long JM, Zhang L, Galemore ER, VandeWoude S, Dean GA. Partial regulatory T cell depletion prior to acute feline immunodeficiency virus infection does not alter disease pathogenesis. PLoS One 2011; 6:e17183.
    • (2011) PLoS One , vol.6
    • Mikkelsen, S.R.1    Long, J.M.2    Zhang, L.3    Galemore, E.R.4    Vandewoude, S.5    Dean, G.A.6
  • 24
    • 34247632512 scopus 로고    scopus 로고
    • Simian immunodeficiency virus (SIV) infection influences the level and function of regulatory T cells in SIV-infected rhesus macaques but not SIV-infected sooty mangabeys
    • Pereira LE, Villinger F, Onlamoon N, Bryan P, Cardona A, Pattanapanysat K, et al. Simian immunodeficiency virus (SIV) infection influences the level and function of regulatory T cells in SIV-infected rhesus macaques but not SIV-infected sooty mangabeys. J Virol 2007; 81:4445-4456.
    • (2007) J Virol , vol.81 , pp. 4445-4456
    • Pereira, L.E.1    Villinger, F.2    Onlamoon, N.3    Bryan, P.4    Cardona, A.5    Pattanapanysat, K.6
  • 25
    • 34249852256 scopus 로고    scopus 로고
    • HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
    • Saez-Cirion A, Lacabaratz C, Lambotte O, Versmisse P, Urrutia A, Boufassa F, et al. HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc Natl Acad Sci U S A 2007; 104:6776-6781.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 6776-6781
    • Saez-Cirion, A.1    Lacabaratz, C.2    Lambotte, O.3    Versmisse, P.4    Urrutia, A.5    Boufassa, F.6
  • 26
    • 10744231165 scopus 로고    scopus 로고
    • CD38 expression on CD8 T lymphocytes as a marker of residual virus replication in chronically HIV-infected patients receiving antiretroviral therapy
    • Benito JM, Lopez M, Lozano S, Martinez P, Gonzalez-Lahoz J, Soriano V. CD38 expression on CD8 T lymphocytes as a marker of residual virus replication in chronically HIV-infected patients receiving antiretroviral therapy. AIDS Res Hum Retroviruses 2004; 20:227-233.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 227-233
    • Benito, J.M.1    Lopez, M.2    Lozano, S.3    Martinez, P.4    Gonzalez-Lahoz, J.5    Soriano, V.6
  • 28
    • 0033562984 scopus 로고    scopus 로고
    • Regulation of apoptosis in mature alphabetaRCD4SCD8S antigen-specific suppressor T cell clones
    • Khan Q, Penninger JM, Yang L, Marra LE, Kozieradzki I, Zhang L. Regulation of apoptosis in mature alphabetaRCD4SCD8S antigen-specific suppressor T cell clones. J Immunol 1999; 162:5860-5867.
    • (1999) J Immunol , vol.162 , pp. 5860-5867
    • Khan, Q.1    Penninger, J.M.2    Yang, L.3    Marra, L.E.4    Kozieradzki, I.5    Zhang, L.6
  • 29
    • 40949110212 scopus 로고    scopus 로고
    • Double-negative regulatory T cells induce allotolerance when expanded after allogeneic haematopoietic stem cell transplantation
    • McIver Z, Serio B, Dunbar A, O'Keefe CL, Powers J, Wlodarski M, et al. Double-negative regulatory T cells induce allotolerance when expanded after allogeneic haematopoietic stem cell transplantation. Br J Haematol 2008; 141:170-178.
    • (2008) Br J Haematol , vol.141 , pp. 170-178
    • McIver, Z.1    Serio, B.2    Dunbar, A.3    O'Keefe, C.L.4    Powers, J.5    Wlodarski, M.6
  • 30
    • 79954431750 scopus 로고    scopus 로고
    • Characterization of the immunoregulatory function of human TCR-alphabetaRCD4SCD8S double-negative T cells
    • Voelkl S, Gary R, Mackensen A. Characterization of the immunoregulatory function of human TCR-alphabetaRCD4SCD8S double-negative T cells. Eur J Immunol 2011; 41:739-748.
    • (2011) Eur J Immunol , vol.41 , pp. 739-748
    • Voelkl, S.1    Gary, R.2    MacKensen, A.3
  • 31
    • 33750814875 scopus 로고    scopus 로고
    • Doublenegative T cells, activated by xenoantigen, lyse autologous B and T cells using a perforin/granzyme-dependent, Fas-Fas ligand-independent pathway
    • Zhang ZX, Ma Y, Wang H, Arp J, Jiang J, Huang X, et al. Doublenegative T cells, activated by xenoantigen, lyse autologous B and T cells using a perforin/granzyme-dependent, Fas-Fas ligand-independent pathway. J Immunol 2006; 177:6920-6929.
    • (2006) J Immunol , vol.177 , pp. 6920-6929
    • Zhang, Z.X.1    Ma, Y.2    Wang, H.3    Arp, J.4    Jiang, J.5    Huang, X.6
  • 33
    • 38149047616 scopus 로고    scopus 로고
    • Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease
    • Bhagat G, Naiyer AJ, Shah JG, Harper J, Jabri B, Wang TC, et al. Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease. J Clin Invest 2008; 118:281-293.
    • (2008) J Clin Invest , vol.118 , pp. 281-293
    • Bhagat, G.1    Naiyer, A.J.2    Shah, J.G.3    Harper, J.4    Jabri, B.5    Wang, T.C.6
  • 34
    • 79960641911 scopus 로고    scopus 로고
    • Innate gamma/delta T-cells during HIV infection: Terra relatively incognita in novel vaccination strategies?
    • Agrati C, D'Offizi G, Gougeon ML, Malkovsky M, Sacchi A, Casetti R, et al. Innate gamma/delta T-cells during HIV infection: Terra relatively incognita in novel vaccination strategies? AIDS Rev 2011; 13:3-12.
    • (2011) AIDS Rev , vol.13 , pp. 3-12
    • Agrati, C.1    D'Offizi, G.2    Gougeon, M.L.3    Malkovsky, M.4    Sacchi, A.5    Casetti, R.6
  • 35
    • 33646874429 scopus 로고    scopus 로고
    • TCR gamma delta intraepithelial lymphocytes are required for selftolerance
    • Locke NR, Stankovic S, Funda DP, Harrison LC. TCR gamma delta intraepithelial lymphocytes are required for selftolerance. J Immunol 2006; 176:6553-6559.
    • (2006) J Immunol , vol.176 , pp. 6553-6559
    • Locke, N.R.1    Stankovic, S.2    Funda, D.P.3    Harrison, L.C.4
  • 36
    • 34548024379 scopus 로고    scopus 로고
    • Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway
    • Peng G, Wang HY, Peng W, Kiniwa Y, Seo KH, Wang RF. Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway. Immunity 2007; 27: 334-348.
    • (2007) Immunity , vol.27 , pp. 334-348
    • Peng, G.1    Wang, H.Y.2    Peng, W.3    Kiniwa, Y.4    Seo, K.H.5    Wang, R.F.6
  • 37
    • 0034254303 scopus 로고    scopus 로고
    • Adoptively transferred gamma delta T cells indirectly regulate murine graftversus-host reactivity following donor leukocyte infusion therapy in mice
    • Drobyski WR, Vodanovic-Jankovic S, Klein J. Adoptively transferred gamma delta T cells indirectly regulate murine graftversus-host reactivity following donor leukocyte infusion therapy in mice. J Immunol 2000; 165:1634-1640.
    • (2000) J Immunol , vol.165 , pp. 1634-1640
    • Drobyski, W.R.1    Vodanovic-Jankovic, S.2    Klein, J.3
  • 38
    • 73949129793 scopus 로고    scopus 로고
    • Interleukin-17-producing gamma delta plus T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-beta
    • Han GC, Wang RX, Chen GJ, Wang JN, Xu RN, Wang LY, et al. Interleukin-17-producing gamma delta plus T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-beta. Immunology 2010; 129:197-206.
    • (2010) Immunology , vol.129 , pp. 197-206
    • Han, G.C.1    Wang, R.X.2    Chen, G.J.3    Wang, J.N.4    Xu, R.N.5    Wang, L.Y.6
  • 39
    • 0036018995 scopus 로고    scopus 로고
    • Dominant IL-10 and TGF-beta mRNA expression in gamma delta T cells of human early pregnancy decidua suggests immunoregulatory potential
    • Nagaeva O, Jonsson L, Mincheva-Nilsson L. Dominant IL-10 and TGF-beta mRNA expression in gammadeltaT cells of human early pregnancy decidua suggests immunoregulatory potential. Am J Reprod Immunol 2002; 48:9-17.
    • (2002) Am J Reprod Immunol , vol.48 , pp. 9-17
    • Nagaeva, O.1    Jonsson, L.2    Mincheva-Nilsson, L.3
  • 40
    • 0033168162 scopus 로고    scopus 로고
    • Depletion of IL-10 and TGF-beta-producing regulatory gamma delta T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells
    • Seo N, Tokura Y, Takigawa M, Egawa K. Depletion of IL-10 and TGF-beta-producing regulatory gamma delta T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells. J Immunol 1999; 163:242-249.
    • (1999) J Immunol , vol.163 , pp. 242-249
    • Seo, N.1    Tokura, Y.2    Takigawa, M.3    Egawa, K.4
  • 41
    • 1542723004 scopus 로고    scopus 로고
    • Increased plasma transforming growth factor-beta1 is associated with disease progression in HIV-1-infected patients
    • Wiercinska-Drapalo A, Flisiak R, Jaroszewicz J, Prokopowicz D. Increased plasma transforming growth factor-beta1 is associated with disease progression in HIV-1-infected patients. Viral Immunol 2004; 17:109-113.
    • (2004) Viral Immunol , vol.17 , pp. 109-113
    • Wiercinska-Drapalo, A.1    Flisiak, R.2    Jaroszewicz, J.3    Prokopowicz, D.4
  • 42
    • 0025909487 scopus 로고
    • Association of circulating receptor Fc gamma RIII-positive monocytes in AIDS patients with elevated levels of transforming growth factor-beta
    • Allen JB, Wong HL, Guyre PM, Simon GL, Wahl SM. Association of circulating receptor Fc gamma RIII-positive monocytes in AIDS patients with elevated levels of transforming growth factor-beta. J Clin Invest 1991; 87:1773-1779.
    • (1991) J Clin Invest , vol.87 , pp. 1773-1779
    • Allen, J.B.1    Wong, H.L.2    Guyre, P.M.3    Simon, G.L.4    Wahl, S.M.5
  • 43
    • 0028271502 scopus 로고
    • Effect of cytokines on HIV replication in CD4R lymphocytes: Lack of identity with the CD8R cell antiviral factor
    • Mackewicz CE, Ortega H, Levy JA. Effect of cytokines on HIV replication in CD4R lymphocytes: lack of identity with the CD8R cell antiviral factor. Cell Immunol 1994; 153: 329-343.
    • (1994) Cell Immunol , vol.153 , pp. 329-343
    • MacKewicz, C.E.1    Ortega, H.2    Levy, J.A.3
  • 44
    • 34548775064 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 suppresses hepatitis B virus replication primarily through transcriptional inhibition of pregenomic RNA
    • Chou YC, Chen ML, Hu CP, Chen YL, Chong CL, Tsai YL, et al. Transforming growth factor-beta1 suppresses hepatitis B virus replication primarily through transcriptional inhibition of pregenomic RNA. Hepatology 2007; 46:672-681.
    • (2007) Hepatology , vol.46 , pp. 672-681
    • Chou, Y.C.1    Chen, M.L.2    Hu, C.P.3    Chen, Y.L.4    Chong, C.L.5    Tsai, Y.L.6
  • 45
    • 0037087471 scopus 로고    scopus 로고
    • DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents
    • Relloso M, Puig-Kroger A, Pello OM, Rodriguez-Fernandez JL, de la Rosa G, Longo N, et al. DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents. J Immunol 2002; 168:2634-2643.
    • (2002) J Immunol , vol.168 , pp. 2634-2643
    • Relloso, M.1    Puig-Kroger, A.2    Pello, O.M.3    Rodriguez-Fernandez, J.L.4    De La Rosa, G.5    Longo, N.6
  • 46
    • 42049095290 scopus 로고    scopus 로고
    • The mucosal barrier and immune activation in HIV pathogenesis
    • Brenchley JM, Douek DC. The mucosal barrier and immune activation in HIV pathogenesis. Curr Opin HIV AIDS 2008; 3:356-361.
    • (2008) Curr Opin HIV AIDS , vol.3 , pp. 356-361
    • Brenchley, J.M.1    Douek, D.C.2
  • 47
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006; 12:1365-1371.
    • (2006) Nat Med , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3    Asher, T.E.4    Silvestri, G.5    Rao, S.6
  • 48
    • 40549113336 scopus 로고    scopus 로고
    • Mucosal IL-10 and TGF-beta play crucial roles in preventing LPS-driven, IFN-gamma-mediated epithelial damage in human colon explants
    • Jarry A, Bossard C, Bou-Hanna C, Masson D, Espaze E, Denis MG, et al. Mucosal IL-10 and TGF-beta play crucial roles in preventing LPS-driven, IFN-gamma-mediated epithelial damage in human colon explants. J Clin Invest 2008; 118: 1132-1142.
    • (2008) J Clin Invest , vol.118 , pp. 1132-1142
    • Jarry, A.1    Bossard, C.2    Bou-Hanna, C.3    Masson, D.4    Espaze, E.5    Denis, M.G.6


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