Histamine 3 receptor activation reduces the expression of neuronal angiotensin II type 1 receptors in the heart

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 1, 2012, Pages 185-191

  Hashikawa Hobara, Narumi ^a   Chan, Noel Yan Ki ^a   Levi, Roberto ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CARIPORIDE; CLOBENPROPIT; COMPLEMENTARY DNA; HISTAMINE H3 RECEPTOR; N(G) METHYLARGININE; NITRIC OXIDE; NORADRENALIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; SODIUM PROTON EXCHANGE PROTEIN;

ACIDIFICATION; ADRENERGIC NERVE CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HEART ARRHYTHMIA; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; ISOLATED HEART; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RECEPTOR BLOCKING; RECEPTOR DOWN REGULATION; SYMPATHETIC INNERVATION;

ANGIOTENSIN II; ANIMALS; GUINEA PIGS; HEART; HISTAMINE AGONISTS; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NERVE ENDINGS; NEURONS; NITRIC OXIDE; PC12 CELLS; PROTEIN KINASE C; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, HISTAMINE H3; SODIUM-HYDROGEN ANTIPORTER; SYMPATHETIC NERVOUS SYSTEM; SYNAPTOSOMES; TETRADECANOYLPHORBOL ACETATE;

EID: 84055213550     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.187765     Document Type: Article

References (46)

1. + exchanger activity: signalling and significance. Cardiovasc Res 57:942-952.
2. 3 receptor negatively coupled to phosphoinositide turnover in the human gastric cell line HGT1. J Biol Chem 267:25315-25320.
3. Connelly WM, Shenton FC, Lethbridge N, Leurs R, Waldvogel HJ, Faull RL, Lees G, and Chazot PL (2009) The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS. Br J Pharmacol 157:55-63.
4. Corti F, Olson KE, Marcus AJ, and Levi R (2011) The expression level of ecto-NTP diphosphohydrolase1/CD39 modulates exocytotic and ischemic release of neurotransmitters in a cellular model of sympathetic neurons. J Pharmacol Exp Ther 337:524-532.
5. Doobay MF, Talman LS, Obr TD, Tian X, Davisson RL, and Lazartigues E (2007) Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol 292:R373-R381.
6. Ferrario CM (2010) New physiological concepts of the renin-angiotensin system from the investigation of precursors and products of angiotensin I metabolism. Hypertension 55:445-452.
7. 3 receptor agonist. J Pharmacol Exp Ther 263:304-310.
8. Gildea JJ, Wang X, Jose PA, and Felder RA (2008) Differential D1 and D5 receptor regulation and degradation of the angiotensin type 1 receptor. Hypertension 51: 360-366. (Pubitemid 351159951)
9. Harada K, Komuro I, Hayashi D, Sugaya T, Murakami K, and Yazaki Y (1998) Angiotensin II type 1a receptor is involved in the occurrence of reperfusion arrhythmias. Circulation 97:315-317. (Pubitemid 28074330)
10. 3 receptors inhibits carrier-mediated norepinephrine release in a human model of protracted myocardial ischemia. J Pharmacol Exp Ther 283:494-500.
11. Ichiki T, Usui M, Kato M, Funakoshi Y, Ito K, Egashira K, and Takeshita A (1998) Down-regulation of angiotensin II type 1 receptor gene transcription by nitric oxide. Hypertension 31:342-348.
12. 3 receptors inhibits carrier-mediated norepinephrine release during protracted myocardial ischemia. Comparison with adenosine A1 receptors and 2-adrenoceptors. Circ Res 78:475-481.
13. 3 receptors in myocardial ischemia: their role as regulators of exocytotic norepinephrine release. J Pharmacol Exp Ther 271:1259-1266.
14. Iravanian S and Dudley SC, Jr. (2008) The renin-angiotensin-aldosterone system (RAAS) and cardiac arrhythmias. Heart Rhythm 5:S12-S17.
15. + exchange: structure, regulation, and its role in heart disease. Circ Res 85:777-786.
16. Koda K, Salazar-Rodriguez M, Corti F, Chan NY, Estephan R, Silver RB, Mochly- Rosen D, and Levi R (2010) Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells. Circulation 122:771-781.
17. Koyama M, Heerdt PM, and Levi R (2003a) Increased severity of reperfusion ar-rhythmias in mouse hearts lacking histamine H3 receptors. Biochem Biophys Res Commun 306:792-796. (Pubitemid 37323832)
18. Koyama M, Seyedi N, Fung-Leung WP, Lovenberg TW, and Levi R (2003b) Norepinephrine release from the ischemic heart is greatly enhanced in mice lacking histamine H3 receptors. Mol Pharmacol 63:378-382. (Pubitemid 36158373)
19. Lecour S, Maupoil V, Zeller M, Laubriet A, Briot T, and Rochette L (2001) Levels of nitric oxide in the heart after experimental myocardial ischemia. J Cardiovasc Pharmacol 37:55-63. (Pubitemid 32012932)
20. 3 receptors: a new frontier in myocardial ischemia. J Pharmacol Exp Ther 292:825-830.
21. Lim HD, van Rijn RM, Ling P, Bakker RA, Thurmond RL, and Leurs R (2005) Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective histamine H4 receptor agonist. J Pharmacol Exp Ther 314:1310-1321. (Pubitemid 41205997)
22. Mackins CJ, Kano S, Seyedi N, Schäfer U, Reid AC, Machida T, Silver RB, and Levi R (2006) Cardiac mast cell-derived renin promotes local angiotensin formation, norepinephrine release, and arrhythmias in ischemia/reperfusion. J Clin Invest 116:1063-1070.
23. Mackins CJ and Levi R (2000) Therapeutic potential of H3 receptor agonists in myocardial infarction. Expert Opin Investig Drugs 9:2537-2542.
24. Maruyama R, Hatta E, and Levi R (1999) Norepinephrine release and ventricular fibrillation in myocardial ischemia/reperfusion: roles of angiotensin and bradykinin. J Cardiovasc Pharmacol 34:913-915.
25. Meredith IT, Broughton A, Jennings GL, and Esler MD (1991) Evidence of a selective increase in cardiac sympathetic activity in patients with sustained ventricular arrhythmias. N Engl J Med 325:618-624.
26. Morrey C, Brazin J, Seyedi N, Corti F, Silver RB, and Levi R (2010) Interaction between sensory C-fibers and cardiac mast cells in ischemia/reperfusion: activation of a local renin-angiotensin system culminating in severe arrhythmic dysfunction. J Pharmacol Exp Ther 335:76-84.
27. 2+ channels. J Pharmacol Exp Ther 326:871-878.
28. Ping P, Takano H, Zhang J, Tang XL, Qiu Y, Li RC, Banerjee S, Dawn B, Balafonova Z, and Bolli R (1999) Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: a signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning. Circ Res 84:587-604. (Pubitemid 29138595)
29. Poole-Wilson PA (1989) Regulation of intracellular pH in the myocardium; relevance to pathology. Mol Cell Biochem 89:151-155.
30. Prasad MR and Jones RM (1992) Enhanced membrane protein kinase C activity in myocardial ischemia. Basic Res Cardiol 87:19-26.
31. Raizada MK and Ferreira AJ (2007) ACE2: a new target for cardiovascular disease therapeutics. J Cardiovasc Pharmacol 50:112-119. (Pubitemid 47267736)
32. Reid AC, Mackins CJ, Seyedi N, Levi R, and Silver RB (2004) Coupling of angiotensin II AT1 receptors to neuronal NHE activity and carrier-mediated norepinephrine release in myocardial ischemia. Am J Physiol Heart Circ Physiol 286:H1448-H1454. (Pubitemid 38381154)
33. Reid AC, Silver RB, and Levi R (2007) Renin: at the heart of the mast cell. Immunol Rev 217:123-140. (Pubitemid 46718147)
34. Santos RA, Simoes e Silva AC, Maric C, Silva DM, Machado RP, de Buhr I, Heringer- Walther S, Pinheiro SV, Lopes MT, Bader M, et al. (2003) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A 100:8258-8263. (Pubitemid 36842532)
35. Schömig A (1990) Catecholamines in myocardial ischemia. Systemic and cardiac release. Circulation 82:II13-II22.
36. Seyedi N, Maruyama R, and Levi R (1999) Bradykinin activates a cross-signaling pathway between sensory and adrenergic nerve endings in the heart: a novel mechanism of ischemic norepinephrine release? J Pharmacol Exp Ther 290:656-663. (Pubitemid 29344559)
37. + exchange: a novel protective mechanism in myocardial ischemia. Proc Natl Acad Sci U S A 98:2855-2859.
38. 1 Receptor- independent activation of protein kinase C in acute myocardial ischemia. Mechanisms for sensitization of the adenylyl cyclase system. Circ Res 70:1304-1312.
39. Taupenot L (2007) Analysis of regulated secretion using PC12 cells. Curr Protoc Cell Biol Chapter 15, Unit 15.12.
40. Tsutsumi Y, Matsubara H, Masaki H, Kurihara H, Murasawa S, Takai S, Miyazaki M, Nozawa Y, Ozono R, Nakagawa K, et al. (1999) Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation. J Clin Invest 104:925-935. (Pubitemid 29536342)
41. + exchangers. Physiol Rev 77:51-74.
42. Walker MJ, Curtis MJ, Hearse DJ, Campbell RW, Janse MJ, Yellon DM, Cobbe SM, Coker SJ, Harness JB, and Harron DW (1988) The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction and reperfusion. Cardiovasc Res 22:447-455.
43. Yahiro E, Ideishi M, Wang LX, Urata H, Kumagai K, Arakawa K, and Saku K (2003) Reperfusion-induced arrhythmias are suppressed by inhibition of the angiotensin II type 1 receptor. Cardiology 99:61-67. (Pubitemid 36506382)
44. Zhou J, Pavel J, Macova M, Yu ZX, Imboden H, Ge L, Nishioku T, Dou J, Delgiacco E, and Saavedra JM (2006) AT1 receptor blockade regulates the local angiotensin II system in cerebral microvessels from spontaneously hypertensive rats. Stroke 37:1271-1276. (Pubitemid 43731875)
45. Zweier JL, Wang P, and Kuppusamy P (1995a) Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy. J Biol Chem 270:304-307.
46. Zweier JL, Wang P, Samouilov A, and Kuppusamy P (1995b) Enzyme-independent formation of nitric oxide in biological tissues. Nat Med 1:804-809.