메뉴 건너뛰기




Volumn 34, Issue 1, 2012, Pages 56-65

WNT/β-catenin pathway is modulated in asthma patients and LPS-stimulated RAW264.7 macrophage cell line

Author keywords

Cytokine; Hyperactivation; IL 6; Inflammation; NF B

Indexed keywords

AXIN; BETA CATENIN; DISHEVELLED 2; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MESSENGER RNA; SMALL INTERFERING RNA; WNT PROTEIN;

EID: 84055190357     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2011.574704     Document Type: Article
Times cited : (45)

References (74)
  • 2
    • 66349130447 scopus 로고    scopus 로고
    • Regulation of macrophage function in inflammation and atherosclerosis
    • Shibata, N., Glass, C.K. Regulation of macrophage function in inflammation and atherosclerosis. J Lipid Res 2009, 50 Suppl, S277-S281.
    • (2009) J. Lipid. Res. , vol.50
    • Shibata, N.1    Glass, C.K.2
  • 5
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995, 13, 251-276.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 6
    • 34548583437 scopus 로고    scopus 로고
    • Innate immunity, macrophage activation, and atherosclerosis
    • DOI 10.1111/j.1600-065X.2007.00554.x
    • Yan, Z.Q., Hansson, G.K. Innate immunity, macrophage activation, and atherosclerosis. Immunol Rev 2007, 219, 187-203. (Pubitemid 47390007)
    • (2007) Immunological Reviews , vol.219 , Issue.1 , pp. 187-203
    • Yan, Z.-Q.1    Hansson, G.K.2
  • 7
    • 0029890168 scopus 로고    scopus 로고
    • Endotoxin signal transduction in macrophages
    • Sweet, M.J., Hume, D.A. Endotoxin signal transduction in macrophages. J Leukoc Biol 1996, 60, 8-26. (Pubitemid 26248877)
    • (1996) Journal of Leukocyte Biology , vol.60 , Issue.1 , pp. 8-26
    • Sweet, M.J.1    Hume, D.A.2
  • 8
    • 0032013322 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced NF-κB activation and cytokine release in human alveolar macrophages is PKC-independent and TK- and PC-PLC-dependent
    • Carter, A.B., Monick, M.M., Hunninghake, G.W. Lipopolysaccharide-induced NF-kappaB activation and cytokine release in human alveolar macrophages is PKC-independent and TK- and PC-PLC-dependent. Am J Respir Cell Mol Biol 1998, 18, 384-391. (Pubitemid 128354096)
    • (1998) American Journal of Respiratory Cell and Molecular Biology , vol.18 , Issue.3 , pp. 384-391
    • Carter, A.B.1    Monick, M.M.2    Hunninghake, G.W.3
  • 10
    • 0028068084 scopus 로고
    • Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-α and IL-1β production by human monocytes
    • Shapira, L., Takashiba, S., Champagne, C., Amar, S., Van Dyke, T.E. Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-alpha and IL-1 beta production by human monocytes. J Immunol 1994, 153, 1818-1824. (Pubitemid 24251127)
    • (1994) Journal of Immunology , vol.153 , Issue.4 , pp. 1818-1824
    • Shapira, L.1    Takashiba, S.2    Champagne, C.3    Amar, S.4    Van Dyke, T.E.5
  • 13
    • 0025260779 scopus 로고
    • Regulation of tumor necrosis factor alpha transcription in macrophages: Involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B
    • Collart, M.A., Baeuerle, P., Vassalli, P. Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B. Mol Cell Biol 1990, 10, 1498-1506.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 1498-1506
    • Collart, M.A.1    Baeuerle, P.2    Vassalli, P.3
  • 15
    • 0025343895 scopus 로고
    • Activation of interleukin-6 gene expression through the NF-kappa B transcription factor
    • Libermann, T.A., Baltimore, D. Activation of interleukin-6 gene expression through the NF-kappa B transcription factor. Mol Cell Biol 1990, 10, 2327-2334.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 2327-2334
    • Libermann, T.A.1    Baltimore, D.2
  • 17
    • 0028169399 scopus 로고
    • Localization of the human beta-catenin gene CTNNB1 to 3p21: A region implicated in tumor development
    • Kraus, C., Liehr, T., Hülsken, J., Behrens, J., Birchmeier, W., Grzeschik, K.H., Ballhausen, W.G. Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development. Genomics 1994, 23, 272-274.
    • (1994) Genomics , vol.23 , pp. 272-274
    • Kraus, C.1    Liehr, T.2    Hülsken, J.3    Behrens, J.4    Birchmeier, W.5    Grzeschik, K.H.6    Ballhausen, W.G.7
  • 18
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through β-catenin
    • DOI 10.1126/science.1071549
    • Moon, R.T., Bowerman, B., Boutros, M., Perrimon, N. The promise and perils of Wnt signaling through beta-catenin. Science 2002, 296, 1644-1646. (Pubitemid 34579151)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 19
    • 0041695485 scopus 로고    scopus 로고
    • A second canon: Functions and mechanisms of β-catenin-independent Wnt signaling
    • DOI 10.1016/S1534-5807(03)00266-1, PII S1534580703002661
    • Veeman, M.T., Axelrod, J.D., Moon, R.T. A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell 2003, 5, 367-377. (Pubitemid 37107667)
    • (2003) Developmental Cell , vol.5 , Issue.3 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 21
    • 33644967242 scopus 로고    scopus 로고
    • Wnt signaling: Complexity at the surface
    • Cadigan, K.M., Liu, Y.I. Wnt signaling: complexity at the surface. J Cell Sci 2006, 119, 395-402.
    • (2006) J. Cell Sci. , vol.119 , pp. 395-402
    • Cadigan, K.M.1    Liu, Y.I.2
  • 22
    • 0031888098 scopus 로고    scopus 로고
    • Beta-catenin: A key mediator of wnt signaling
    • Willert, K., Nusse, R. Beta-catenin: a key mediator of Wnt signaling. Curr Opin Genet Dev 1998, 8, 95-102.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 95-102
    • Willert, K.1    Nusse, R.2
  • 23
    • 0036860704 scopus 로고    scopus 로고
    • The Wnt signalling pathway
    • DOI 10.1242/jcs.00089
    • Huelsken, J., Behrens, J. The Wnt signalling pathway. J Cell Sci 2002, 115, 3977-3978. (Pubitemid 35446796)
    • (2002) Journal of Cell Science , vol.115 , Issue.21 , pp. 3977-3978
    • Huelsken, J.1    Behrens, J.2
  • 24
    • 34249034925 scopus 로고    scopus 로고
    • β-Catenin activity negatively regulates bacteria-induced inflammation
    • DOI 10.1038/labinvest.3700545, PII 3700545
    • Duan, Y., Liao, A.P., Kuppireddi, S., Ye, Z., Ciancio, M.J., Sun, J. Beta-catenin activity negatively regulates bacteria-induced inflammation. Lab Invest 2007, 87, 613-624. (Pubitemid 46788789)
    • (2007) Laboratory Investigation , vol.87 , Issue.6 , pp. 613-624
    • Duan, Y.1    Liao, A.P.2    Kuppireddi, S.3    Ye, Z.4    Ciancio, M.J.5    Sun, J.6
  • 25
    • 77953555446 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta and betacatenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages
    • Kim, J.S., Yeo, S., Shin, D.G., Bae, Y.S., Lee, J.J., Chin, B.R., Lee, C.H., Baek, S.H. Glycogen synthase kinase 3beta and betacatenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages. FEBS J 2010, 277, 2830-2837.
    • (2010) FEBS J. , vol.277 , pp. 2830-2837
    • Kim, J.S.1    Yeo, S.2    Shin, D.G.3    Bae, Y.S.4    Lee, J.J.5    Chin, B.R.6    Lee, C.H.7    Baek, S.H.8
  • 26
    • 0035313040 scopus 로고    scopus 로고
    • Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of β-catenin
    • Monick, M.M., Carter, A.B., Robeff, P.K., Flaherty, D.M., Peterson, M.W., Hunninghake, G.W. Lipopolysaccharide activates Akt inhuman alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin. J Immunol 2001, 166, 4713-4720. (Pubitemid 32233759)
    • (2001) Journal of Immunology , vol.166 , Issue.7 , pp. 4713-4720
    • Monick, M.M.1    Carter, A.B.2    Robeff, P.K.3    Flaherty, D.M.4    Peterson, M.W.5    Hunninghake, G.W.6
  • 28
    • 58149198796 scopus 로고    scopus 로고
    • IFN-beta production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-beta
    • Wang, H., Garcia, C.A., Rehani, K., Cekic, C., Alard, P., Kinane, D.F., Mitchell, T., Martin, M. IFN-beta production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-beta. J Immunol 2008, 181, 6797-6802.
    • (2008) J. Immunol. , vol.181 , pp. 6797-6802
    • Wang, H.1    Garcia, C.A.2    Rehani, K.3    Cekic, C.4    Alard, P.5    Kinane, D.F.6    Mitchell, T.7    Martin, M.8
  • 29
    • 0023567409 scopus 로고
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease COPD and asthma this official statement of the American Thoracic Society was adopted by the ATS Board of directors
    • November 1986
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. Am Rev Respir Dis 1987, 136, 225-244.
    • (1987) Am. Rev. Respir. Dis. , vol.136 , pp. 225-244
  • 33
    • 0035710746 scopus 로고    scopus 로고
    • -δδCT method
    • DOI 10.1006/meth.2001.1262
    • Livak, K.J., Schmittgen, T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001, 25, 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 36
    • 0028221482 scopus 로고
    • IL-6, IL-8 and TNF production by cytokine and lipopolysaccharide- stimulated-human renal cortical epithelial cells in vitro
    • Von Asmuth, E.J., Dentener, M.A., Ceska, M., Buurman, W.A. IL-6, IL-8 and TNF production by cytokine and lipopolysaccharidestimulated human renal cortical epithelial cells in vitro. Eur Cytokine Netw 1994, 5, 301-310. (Pubitemid 24212016)
    • (1994) European Cytokine Network , vol.5 , Issue.3 , pp. 301-310
    • Von Asmuth, E.J.U.1    Dentener, M.A.2    Ceska, M.3    Buurman, W.A.4    Asmuthl, E.J.U.V.5
  • 37
    • 0027198202 scopus 로고
    • Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1
    • Romero, L.I., Schettini, G., Lechan, R.M., Dinarello, C.A., Reichlin, S. Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1. Neuroendocrinology 1993, 57, 892-897. (Pubitemid 23249934)
    • (1993) Neuroendocrinology , vol.57 , Issue.5 , pp. 892-897
    • Romero, L.I.1    Schettini, G.2    Lechan, R.M.3    Dinarello, C.A.4    Reichlin, S.5
  • 38
    • 0024586781 scopus 로고
    • Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells
    • Jirik, F.R., Podor, T.J., Hirano, T., Kishimoto, T., Loskutoff, D.J., Carson, D.A., Lotz, M. Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J Immunol 1989, 142, 144-147. (Pubitemid 19034734)
    • (1989) Journal of Immunology , vol.142 , Issue.1 , pp. 144-147
    • Jirik, F.R.1    Podor, T.J.2    Hirano, T.3    Kishimoto, T.4    Loskutoff, D.J.5    Carson, D.A.6    Lotz, M.7
  • 39
    • 0037199972 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
    • DOI 10.1074/jbc.M203298200
    • Guha, M., Mackman, N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J Biol Chem 2002, 277, 32124-32132. (Pubitemid 34969025)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.35 , pp. 32124-32132
    • Guha, M.1    Mackman, N.2
  • 40
    • 52449091206 scopus 로고    scopus 로고
    • Lipopolysaccharide LPS of porphyromonas gingivalis induces IL-1beta TNF-alpha and IL-6 production by THP-1 cells in a way different from that of escherichia coli LPS
    • Diya, Z., Lili, C., Shenglai, L., Zhiyuan, G., Jie, Y. Lipopolysaccharide (LPS) of Porphyromonas gingivalis induces IL-1beta, TNF-alpha and IL-6 production by THP-1 cells in a way different from that of Escherichia coli LPS. Innate Immun 2008, 14, 99-107.
    • (2008) Innate. Immun. , vol.14 , pp. 99-107
    • Diya, Z.1    Lili, C.2    Shenglai, L.3    Zhiyuan, G.4    Jie, Y.5
  • 41
    • 14844344042 scopus 로고    scopus 로고
    • The nuclear IκB protein IκBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria
    • Hirotani, T., Lee, P.Y., Kuwata, H., Yamamoto, M., Matsumoto, M., Kawase, I., Akira, S., Takeda, K. The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria. J Immunol 2005, 174, 3650-3657. (Pubitemid 40354075)
    • (2005) Journal of Immunology , vol.174 , Issue.6 , pp. 3650-3657
    • Hirotani, T.1    Lee, P.Y.2    Kuwata, H.3    Yamamoto, M.4    Matsumoto, M.5    Kawase, I.6    Akira, S.7    Takeda, K.8
  • 43
    • 40749157135 scopus 로고    scopus 로고
    • Wnt pathway: A new role in regulation of inflammation
    • George, S.J. Wnt pathway: a new role in regulation of inflammation. Arterioscler Thromb Vasc Biol 2008, 28, 400-402.
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 400-402
    • George, S.J.1
  • 44
    • 65449123456 scopus 로고    scopus 로고
    • The wnt pathway: A macrophage effector molecule that triggers inflammation
    • Pereira, C.P., Bachli, E.B., Schoedon, G. The wnt pathway: a macrophage effector molecule that triggers inflammation. Curr Atheroscler Rep 2009, 11, 236-242.
    • (2009) Curr. Atheroscler. Rep. , vol.11 , pp. 236-242
    • Pereira, C.P.1    Bachli, E.B.2    Schoedon, G.3
  • 45
    • 43149122725 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses proinflammatory NFkappaB activation through GSK3beta inactivation in renal tubular epithelial cells
    • Gong, R., Rifai, A., Ge, Y., Chen, S., Dworkin, L.D. Hepatocyte growth factor suppresses proinflammatory NFkappaB activation through GSK3beta inactivation in renal tubular epithelial cells. J Biol Chem 2008, 283, 7401-7410.
    • (2008) J. Biol. Chem. , vol.283 , pp. 7401-7410
    • Gong, R.1    Rifai, A.2    Ge, Y.3    Chen, S.4    Dworkin, L.D.5
  • 46
    • 0033119801 scopus 로고    scopus 로고
    • β-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • DOI 10.1038/18884
    • Tetsu, O., McCormick, F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398, 422-426. (Pubitemid 29180374)
    • (1999) Nature , vol.398 , Issue.6726 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 49
    • 77953814158 scopus 로고    scopus 로고
    • Genetic polymorphism of manganese superoxide dismutase is associated with childhood asthma
    • Kuo Chou, T.N., Li, Y.S., Lue, K.H., Liao, C.F., Lin, C.Y., Tzeng, P.R., Wong, R.H. Genetic polymorphism of manganese superoxide dismutase is associated with childhood asthma. J Asthma 2010, 47, 532-538.
    • (2010) J. Asthma. , vol.47 , pp. 532-538
    • Kuo Chou, T.N.1    Li, Y.S.2    Lue, K.H.3    Liao, C.F.4    Lin, C.Y.5    Tzeng, P.R.6    Wong, R.H.7
  • 50
    • 0031842804 scopus 로고    scopus 로고
    • Transcription factors and asthma
    • DOI 10.1183/09031936.98.12010221
    • Barnes, P.J., Adcock, I.M. Transcription factors and asthma. Eur Respir J 1998, 12, 221-234. (Pubitemid 28325681)
    • (1998) European Respiratory Journal , vol.12 , Issue.1 , pp. 221-234
    • Barnes, P.J.1    Adcock, I.M.2
  • 51
    • 0026583649 scopus 로고
    • Expression of the potent inflammatory cytokines granulocyte- macrophagecolony- stimulating factor and interleukin-6 and interleukin-8 in bronchial epithelial cells of patients with asthma
    • Marini, M., Vittori, E., Hollemborg, J., Mattoli, S. Expression of the potent inflammatory cytokines, granulocyte-macrophagecolony- stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma. J Allergy Clin Immunol 1992, 89, 1001-1009.
    • (1992) J. Allergy. Clin. Immunol. , vol.89 , pp. 1001-1009
    • Marini, M.1    Vittori, E.2    Hollemborg, J.3    Mattoli, S.4
  • 52
    • 0031811429 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide-induced sulfidoleukotriene release from peripheral blood leukocytes in patients with asthma and chronic obstructive pulmonary disease
    • Kraus-Filarska, M., Malolepszy, J., Medrala, W., Dobek, R. Bacterial lipopolysaccharide-induced sulfidoleukotriene release from peripheral blood leukocytes in patients with asthma and chronic obstructive pulmonary disease. J Investig Allergol Clin Immunol 1998, 8, 94-97. (Pubitemid 28239237)
    • (1998) Journal of Investigational Allergology and Clinical Immunology , vol.8 , Issue.2 , pp. 94-97
    • Kraus-Filarska, M.1    Malolepszy, J.2    Medrala, W.3    Dobek, R.4
  • 54
    • 55049118368 scopus 로고    scopus 로고
    • A combination of Lox-1 and Nox1 regulates TLR9-mediated foam cell formation
    • Lee, J.G., Lim, E.J., Park, D.W., Lee, S.H., Kim, J.R., Baek, S.H. A combination of Lox-1 and Nox1 regulates TLR9-mediated foam cell formation. Cell Signal 2008, 20, 2266-2275.
    • (2008) Cell Signal , vol.20 , pp. 2266-2275
    • Lee, J.G.1    Lim, E.J.2    Park, D.W.3    Lee, S.H.4    Kim, J.R.5    Baek, S.H.6
  • 55
    • 33750912209 scopus 로고    scopus 로고
    • NADPH oxidases in the gastrointestinal tract: A potential role of Nox1 in innate immune response and carcinogenesis
    • DOI 10.1089/ars.2006.8.1573
    • Rokutan, K., Kawahara, T., Kuwano, Y., Tominaga, K., Sekiyama, A., Teshima-Kondo, S. NADPH oxidases in the gastrointestinal tract: a potential role of Nox1 in innate immune response and carcinogenesis. Antioxid Redox Signal 2006, 8, 1573-1582. (Pubitemid 44726332)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.9-10 , pp. 1573-1582
    • Rokutan, K.1    Kawahara, T.2    Kuwano, Y.3    Tominaga, K.4    Sekiyama, A.5    Teshima-Kondo, S.6
  • 56
    • 0028177849 scopus 로고
    • Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults
    • Akashi, K., Hayashi, S., Gondo, H., Mizuno, S., Harada, M., Tamura, K., Yamasaki, K., Shibuya, T., Uike, N., Okamura, T. Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults. Br J Haematol 1994, 87, 243-250.
    • (1994) Br. J. Haematol. , vol.87 , pp. 243-250
    • Akashi, K.1    Hayashi, S.2    Gondo, H.3    Mizuno, S.4    Harada, M.5    Tamura, K.6    Yamasaki, K.7    Shibuya, T.8    Uike, N.9    Okamura, T.10
  • 57
    • 0027970795 scopus 로고
    • Histiocytes and histiocytosis
    • Cline, M.J. Histiocytes and histiocytosis. Blood 1994, 84, 2840-2853. (Pubitemid 24328071)
    • (1994) Blood , vol.84 , Issue.9 , pp. 2840-2853
    • Cline, M.J.1
  • 61
    • 0041917266 scopus 로고    scopus 로고
    • Th1/Th2 balance: The hypothesis, its limitations, and implications for health and disease
    • Kidd, P. Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease. Altern Med Rev 2003, 8, 223-246. (Pubitemid 37099886)
    • (2003) Alternative Medicine Review , vol.8 , Issue.3 , pp. 223-246
    • Kidd, P.1
  • 62
    • 21344467014 scopus 로고    scopus 로고
    • Th1 and Th2 lymphocytes in autoimmune disease
    • DOI 10.1615/CritRevImmunol.v25.i2.10
    • Crane, I.J., Forrester, J.V. Th1 and Th2 lymphocytes in autoimmune disease. Crit. Rev. Immunol. 2005, 25, 75-102. (Pubitemid 40910583)
    • (2005) Critical Reviews in Immunology , vol.25 , Issue.2 , pp. 75-102
    • Crane, I.J.1    Forrester, J.V.2
  • 63
    • 0037338904 scopus 로고    scopus 로고
    • The role of T lymphocytes in the pathogenesis of asthma
    • DOI 10.1067/mai.2003.169
    • Larché, M., Robinson, D.S., Kay, A.B. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 2003, 111, 450-63; quiz 464. (Pubitemid 36337859)
    • (2003) Journal of Allergy and Clinical Immunology , vol.111 , Issue.3 , pp. 450-463
    • Larche, M.1    Robinson, D.S.2    Kay, A.B.3
  • 64
    • 0031908032 scopus 로고    scopus 로고
    • The TH1/TH2 paradigm in allergy
    • DOI 10.1016/S1380-2933(97)10005-7, PII S1380293397100057
    • Maggi, E. The TH1/TH2 paradigm in allergy. Immunotechnology 1998, 3, 233-244. (Pubitemid 28098326)
    • (1998) Immunotechnology , vol.3 , Issue.4 , pp. 233-244
    • Maggi, E.1
  • 65
    • 0036889996 scopus 로고    scopus 로고
    • The two faces of IL-6 on Th1/Th2 differentiation
    • DOI 10.1016/S0161-5890(02)00210-9, PII S0161589002002109
    • Diehl, S., Rincón, M. The two faces of IL-6 on Th1/Th2 differentiation. Mol Immunol 2002, 39, 531-536. (Pubitemid 35341492)
    • (2002) Molecular Immunology , vol.39 , Issue.9 , pp. 531-536
    • Diehl, S.1    Rincon, M.2
  • 66
    • 0032955469 scopus 로고    scopus 로고
    • Increased bcl-2 expression in lymphocytes and its association with hepatocellular damage in patients with autoimmune hepatitis
    • DOI 10.1046/j.1365-2249.1999.00861.x
    • Yachida, M., Kurokohchi, K., Arima, K., Nishioka, M. Increased bcl-2 expression in lymphocytes and its association with hepatocellular damage in patients with autoimmune hepatitis. Clin Exp Immunol 1999, 116, 140-145. (Pubitemid 29170017)
    • (1999) Clinical and Experimental Immunology , vol.116 , Issue.1 , pp. 140-145
    • Yachida, M.1    Kurokohchi, K.2    Arima, K.3    Nishioka, M.4
  • 68
    • 84055171636 scopus 로고    scopus 로고
    • The soluble interleukin 6 receptor: Generation and role in inflammation and cancer
    • 1016.
    • Chalaris, A., Garbers, C., Rabe, B., Rose-John, S., Scheller, J. The soluble interleukin 6 receptor: generation and role in inflammation and cancer. Eur J Cell Biol 2010; DOI10.1016.
    • (2010) Eur J Cell Biol
    • Chalaris, A.1    Garbers, C.2    Rabe, B.3    Rose-John, S.4    Scheller, J.5
  • 71
    • 23944471116 scopus 로고    scopus 로고
    • Pathological role of IL-6 in the experimental allergic bronchial asthma in mice
    • Doganci, A., Sauer, K., Karwot, R., Finotto, S. Pathological role of IL-6 in the experimental allergic bronchial asthma in mice. Clin Rev Allergy Immunol 2005, 28, 257-270.
    • (2005) Clin. Rev. Allergy Immunol. , vol.28 , pp. 257-270
    • Doganci, A.1    Sauer, K.2    Karwot, R.3    Finotto, S.4
  • 72
  • 73
    • 35648965192 scopus 로고    scopus 로고
    • Interleukin-6 -174G/C polymorphism and ischemic stroke: A systematic review
    • DOI 10.1161/STROKEAHA.107.492231, PII 0000767020071100000033
    • Tso, A.R., Merino, J.G., Warach, S. Interleukin-6 174G/C polymorphism and ischemic stroke: a systematic review. Stroke 2007, 38, 3070-3075. (Pubitemid 350035706)
    • (2007) Stroke , vol.38 , Issue.11 , pp. 3070-3075
    • Tso, A.R.1    Merino, J.G.2    Warach, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.