MIC-1 (a multifunctional modulator of dendritic cell phenotype and function) is produced by decidual stromal cells and trophoblasts

Human Reproduction

Volumn 27, Issue 1, 2012, Pages 200-209

  Segerer, S E ^a   Rieger, L ^a   Kapp, M ^a   Dombrowski, Y ^b   Muller N ^a   Dietl, J ^a   Kammerer U ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

decidua; early pregnancy; MIC 1 dendritic cells

Indexed keywords

CD14 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; DEXAMETHASONE; GROWTH DIFFERENTIATION FACTOR 15; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 2 RECEPTOR ALPHA;

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; CYTOKINE RELEASE; DECIDUA; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MIXED LYMPHOCYTE REACTION; MONOCYTE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; STROMA CELL; T LYMPHOCYTE; TROPHOBLAST; WESTERN BLOTTING;

EID: 83755205859     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/der358     Document Type: Article

References (43)

1. Anacker J, Segerer SE, Hagemann C, Feix S, Kapp M, Bausch R, Kämmerer U. Human decidua and invasive trophoblasts are rich sources of nearly all human matrix metalloproteinases. Mol Hum Reprod 2011;17:637-652.
2. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392:245-252. (Pubitemid 28155090)
3. Beagley KW, Gockel CM. Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone. FEMS Immunol Med Microbiol 2003;38:13-22. (Pubitemid 37297438)
4. Belladonna ML, Volpi C, Bianchi R, Vacca C, Orabona C, Pallotta MT, Boon L, Gizzi S, Fioretti MC, Grohmann U et al. Cutting edge: autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. J Immunol 2008;181:5194-5198.
5. Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, Steinman RM. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 2002;196: 1627-1638. (Pubitemid 36026474)
6. Bootcov MR, Bauskin AR, Valenzuela SM, Moore AG, Bansal M, He XY, Zhang HP, Donnellan M, Mahler S, Pryor K et al. MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proc Natl Acad Sci USA 1997;94:11514-11519. (Pubitemid 27451030)
7. Braun D, Longman RS, Albert ML. A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation. Blood 2005;106:2375-2381. (Pubitemid 41510810)
8. de Jong EC, Vieira PL, Kalinski P, Kapsenberg ML. Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3. J Leukoc Biol 1999;66:201-204. (Pubitemid 29379155)
9. Elenkov IJ. Glucocorticoids and the Th1/Th2 balance. Ann N Y Acad Sci 2004;1024:138-146. (Pubitemid 38879598)
10. Fairlie WD, Moore AG, Bauskin AR, Russell PK, Zhang HP, Breit SN. MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation. J Leukoc Biol 1999;65:2-5. (Pubitemid 29024911)
11. Gomez-Lopez N, Guilbert LJ, Olson DM. Invasion of the leukocytes into the fetal-maternal interface during pregnancy. J Leukoc Biol 2010; 88:625-633.
12. Hill ME, Ferguson DJ, Austyn JM, Newsom-Davis J, Willcox HN. Potent immunostimulatory dendritic cells can be cultured in bulk from progenitors in normal infant and adult myasthenic human thymus. Immunology 1999;97:325-332. (Pubitemid 29274167)
13. Hromas R, Hufford M, Sutton J, Xu D, Li Y, Lu L. PLAB, a novel placental bone morphogenetic protein. Biochim Biophys Acta 1997; 1354:40-44. (Pubitemid 27479891)
14. Jokhi PP, King A, Loke YW. Reciprocal expression of epidermal growth factor receptor (EGF-R) and c-erbB2 by non-invasive and invasive human trophoblast populations. Cytokine 1994;6:433-442. (Pubitemid 24263889)
15. Jones RL, Stoikos C, Findlay JK, Salamonsen LA. TGF-beta superfamily expression and actions in the endometrium and placenta. Reproduction 2006;132:217-232. (Pubitemid 44269704)
16. Katz JB, Muller AJ, Prendergast GC. Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape. Immunol Rev 2008; 222:206-221. (Pubitemid 351430372)
17. Lawton LN, Bonaldo MF, Jelenc PC, Qiu L, Baumes SA, Marcelino RA, de Jesus GM, Wellington S, Knowles JA, Warburton D et al. Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta. Gene 1997;203:17-26. (Pubitemid 27520649)
18. Lee Y, Kim S, Lee ST, Kim HS, Baek EJ, Kim HJ, Lee M, Kim HO. Analysis of characteristics of mononuclear cells remaining in the leukoreduction system chamber of Trima Accel and their differentiation into dendritic cells. Korean J Lab Med 2009;29:353-360.
19. Loke YW, King A. Human implantation. In Cell Biology and Immunology. London: Cambridge University Press, 1995.
20. Lutz MB, Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 2002;23:445-449. (Pubitemid 35015188)
21. Marjono AB, Brown DA, Horton KE, Wallace EM, Breit SN, Manuelpillai U. Macrophage inhibitory cytokine-1 in gestational tissues and maternal serum in normal and pre-eclamptic pregnancy. Placenta 2003;24:100-106. (Pubitemid 37184701)
22. Matasic R, Dietz AB, Vuk-Pavlovic S. Dexamethasone inhibits dendritic cell maturation by redirecting differentiation of a subset of cells. J Leukoc Biol 1999;66:909-914. (Pubitemid 30010514)
23. Moore AG, Brown DA, Fairlie WD, Bauskin AR, Brown PK, Munier ML, Russell PK, Salamonsen LA, Wallace EM, Breit SN. The transforming growth factor-ss superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women. J Clin Endocrinol Metab 2000;85:4781-4788. (Pubitemid 32157666)
24. Morrish DW, Dakour J, Li H. Life and death in the placenta: new peptides and genes regulating human syncytiotrophoblast and extravillous cytotrophoblast lineage formation and renewal. Curr Protein Pept Sci 2001;2:245-259. (Pubitemid 32798794)
25. Mou HB, Lin MF, Cen H, Yu J, Meng XJ. TGF-beta1 treated murine dendritic cells are maturation resistant and down-regulate Toll-like receptor 4 expression. J Zhejiang Univ Sci 2004;5:1239-1244.
26. Munn DH, Mellor AL. Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J Clin Invest 2007;117:1147-1154. (Pubitemid 46718399)
27. Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, Brown C, Mellor AL. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998;281:1191-1193. (Pubitemid 28406294)
28. Piemonti L, Monti P, Allavena P, Leone BE, Caputo A, Di Carlo V. Glucocorticoids affect human dendritic cell differentiation and maturation. J Immunol 1999;162:6473-6481. (Pubitemid 29309369)
29. Rieger L, Honig A, Sutterlin M, Kapp M, Dietl J, Ruck P, Kammerer U. Antigen-presenting cells in human endometrium during the menstrual cycle compared to early pregnancy. J Soc Gynecol Investig 2004; 11:488-493. (Pubitemid 39349202)
30. Romani N, Reider D, Heuer M, Ebner S, Kampgen E, Eibl B, Niederwieser D, Schuler G. Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J Immunol Methods 1996;196:137-151. (Pubitemid 26306735)
31. Rook AH, Kehrl JH,Wakefield LM, Roberts AB, Sporn MB, Burlington DB, Lane HC, Fauci AS. Effects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness. J Immunol 1986; 136:3916-3920. (Pubitemid 16122096)
32. Rutella S, Bonanno G, Procoli A, Mariotti A, de Ritis DG, Curti A, Danese S, Pessina G, Pandolfi S, Natoni F et al. Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features. Blood 2006;108:218-227. (Pubitemid 43990632)
33. Sallusto F, Lanzavecchia A. Mobilizing dendritic cells for tolerance, priming, and chronic inflammation. J Exp Med 1999;189:611-614. (Pubitemid 29193361)
34. Sato K, Yamashita N, Baba M, Matsuyama T. Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood 2003;101:3581-3589. (Pubitemid 36857945)
35. Segerer SE, Muller N, Brandt J, Kapp M, Dietl J, Reichardt HM, Rieger L, Kammerer U. The glycoprotein-hormones activin A and inhibin A interfere with dendritic cell maturation. Reprod Biol Endocrinol 2008;6:17.
36. Segerer SE, Muller N, van den BJ, Kapp M, Dietl J, Reichardt HM, Rieger L, Kammerer U. Impact of female sex hormones on the maturation and function of human dendritic cells. Am J Reprod Immunol 2009; 62:165-173.
37. Senapati S, Rachagani S, Chaudhary K, Johansson SL, Singh RK, Batra SK. Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway. Oncogene 2010;29:1293-1302.
38. Sharma MD, Baban B, Chandler P, Hou DY, Singh N, Yagita H, Azuma M, Blazar BR, Mellor AL, Munn DH. Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase. J Clin Invest 2007;117:2570-2582. (Pubitemid 47494358)
39. Steinman RM. Some interfaces of dendritic cell biology. APMIS 2003; 111:675-697. (Pubitemid 37130017)
40. Strobl H, Knapp W. TGF-beta1 regulation of dendritic cells. Microbes Infect 1999;1:1283-1290.
41. Tong S, Marjono B, Brown DA, Mulvey S, Breit SN, Manuelpillai U, Wallace EM. Serum concentrations of macrophage inhibitory cytokine 1 (MIC 1) as a predictor of miscarriage. Lancet 2004;363:129-130. (Pubitemid 38068331)
42. Wan H, Versnel MA, Leijten LM, van Helden-Meeuwsen CG, Fekkes D, Leenen PJ, Khan NA, Benner R, Kiekens RC. Chorionic gonadotropin induces dendritic cells to express a tolerogenic phenotype. J Leukoc Biol 2008;83:894-901. (Pubitemid 351959869)
43. Xu J, Kimball TR, Lorenz JN, Brown DA, Bauskin AR, Klevitsky R, Hewett TE, Breit SN, Molkentin JD. GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ Res 2006;98:342-350.