α-synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter

Journal of Biological Chemistry

Volumn 286, Issue 51, 2011, Pages 43933-43943

  Swant, Jarod ^a   Goodwin, J Shawn ^a   North, Ashley ^a   Ali, Ahmad Abdul ^b   Gamble George, Joyonna ^a   Chirwa, Sanika ^a   Khoshbouei, Habibeh ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

^b JAMES MADISON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACES; CHO CELL; DOPAMINE TRANSPORTERS; DOPAMINERGIC NEURONS; DRUG ADDICTION; HETEROLOGOUS SYSTEMS; MIDBRAIN; N-METHYLPYRIDINIUM; NEURONAL FUNCTION; NEUROPSYCHIATRIC DISORDER; OVER-EXPRESSION; REAL TIME MONITORING; STABLE COMPLEXES; SUBSTRATE UPTAKE; SYNUCLEIN; TRANSPORT FUNCTION; WHOLE CELL PATCH CLAMP;

AMINO ACIDS; CELL MEMBRANES; CHLORINE COMPOUNDS; DIALYSIS; ELECTROPHYSIOLOGY; NEURODEGENERATIVE DISEASES; NEURONS; SODIUM; SUBSTRATES;

BRAIN;

1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE; 4 [4 (DIMETHYLAMINO)STYRYL] N METHYLPYRIDINIUM; ALPHA SYNUCLEIN; CHLORIDE ION; DOPAMINE TRANSPORTER; PYRIDINIUM DERIVATIVE; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL IMMORTALIZATION; CELL MEMBRANE; CHEMICAL BINDING; CHLORIDE CURRENT; CONTROLLED STUDY; DIALYSIS; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; ION TRANSPORT; MESENCEPHALON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM;

ALPHA-SYNUCLEIN; ANIMALS; BRAIN; CHLORIDES; CHO CELLS; CRICETINAE; CRICETULUS; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FLUORESCENT DYES; HUMANS; MICE; NEURODEGENERATIVE DISEASES; NEURONS; PATCH-CLAMP TECHNIQUES;

EID: 83755181403     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.241232     Document Type: Article

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