Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 1, 2012, Pages

  Kakisaka, Keisuke ^a   Cazanave, Sophie C ^a   Fingas, Christian D ^a   Guicciardi, Maria E ^a   Bronk, Steven F ^a   Werneburg, Nathan W ^a   Mott, Justin L ^a   Gores, Gregory J ^a  

^a MAYO CLINIC   (United States)

Author keywords

C jun nh2 terminal kinase; Endoplasmic reticulum stress; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; P53 upregulated modulator of apoptosis; Palmitate

Indexed keywords

CASPASE; GLYCOGEN SYNTHASE KINASE 3; LYSOPHOSPHATIDYLCHOLINE; PALMITIC ACID; PROTEIN P53; PUMA PROTEIN; SHORT HAIRPIN RNA; STEARIC ACID; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; HUMAN; HUMAN CELL; LIPOTOXICITY; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; EUKARYOTIC INITIATION FACTOR-2; GLYCOGEN SYNTHASE KINASE 3; HEPATOCYTES; HUMANS; LYSOPHOSPHATIDYLCHOLINES; MAP KINASE KINASE 4; MICE; MICE, INBRED C57BL; PALMITATES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; STEARATES; TRANSCRIPTION FACTOR CHOP; TUMOR SUPPRESSOR PROTEINS;

EID: 83755177737     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00301.2011     Document Type: Article

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