-
1
-
-
60849097255
-
Gene-expression signatures in breast cancer
-
Sotiriou C, Pusztai L. Gene-expression signatures in breast cancer. N Engl J Med. 2009;360:790-800.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 790-800
-
-
Sotiriou, C.1
Pusztai, L.2
-
2
-
-
73949136029
-
The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: A retrospective of the last decade
-
Weigelt B, Baehner FL, Reis-Filho JS. The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade. J Pathol. 2010;220:263-280.
-
(2010)
J. Pathol.
, vol.220
, pp. 263-280
-
-
Weigelt, B.1
Baehner, F.L.2
Reis-Filho, J.S.3
-
3
-
-
77953873673
-
Histological types of breast cancer: How special are they
-
Weigelt B, Geyer FC, Reis-Filho JS. Histological types of breast cancer: how special are they? Mol Oncol. 2010; 4:192-208.
-
(2010)
Mol. Oncol.
, vol.4
, pp. 192-208
-
-
Weigelt, B.1
Geyer, F.C.2
Reis-Filho, J.S.3
-
4
-
-
75649149550
-
Histological and molecular types of breast cancer: Is there a unifying taxonomy
-
Weigelt B, Reis-Filho JS. Histological and molecular types of breast cancer: is there a unifying taxonomy? Nat Rev Clin Oncol. 2009;6:718-730.
-
(2009)
Nat. Rev. Clin. Oncol.
, vol.6
, pp. 718-730
-
-
Weigelt, B.1
Reis-Filho, J.S.2
-
5
-
-
33745603978
-
An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen
-
DOI 10.1038/sj.onc.1209415, PII 1209415
-
Doane AS, Danso M, Lal P, et al. An estrogen receptornegative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen. Oncogene. 2006;25:3994-4008. (Pubitemid 43990755)
-
(2006)
Oncogene
, vol.25
, Issue.28
, pp. 3994-4008
-
-
Doane, A.S.1
Danso, M.2
Lal, P.3
Donaton, M.4
Zhang, L.5
Hudis, C.6
Gerald, W.L.7
-
6
-
-
22744448864
-
Identification of molecular apocrine breast tumours by microarray analysis
-
DOI 10.1038/sj.onc.1208561
-
Farmer P, Bonnefoi H, Becette V, et al. Identification of molecular apocrine breast tumours by microarray analysis. Oncogene. 2005;24:4660-4671. (Pubitemid 41032603)
-
(2005)
Oncogene
, vol.24
, Issue.29
, pp. 4660-4671
-
-
Farmer, P.1
Bonnefoi, H.2
Becette, V.3
Tubiana-Hulin, M.4
Fumoleau, P.5
Larsimont, D.6
MacGrogan, G.7
Bergh, J.8
Cameron, D.9
Goldstein, D.10
Duss, S.11
Nicoulaz, A.-L.12
Brisken, C.13
Fiche, M.14
Delorenzi, M.15
Iggo, R.16
-
7
-
-
33646874546
-
The molecular portraits of breast tumors are conserved across microarray platforms
-
Hu Z, Fan C, Oh DS, et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics. 2006;7:96.
-
(2006)
BMC Genomics
, vol.7
, pp. 96
-
-
Hu, Z.1
Fan, C.2
Oh, D.S.3
-
8
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
Lehmann BD, Bauer JA, Chen X, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest. 2011;121:2750-2767.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
-
9
-
-
78049308800
-
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
-
Prat A, Parker JS, Karginova O, et al. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res. 2010;12:R68.
-
(2010)
Breast Cancer Res.
, vol.12
-
-
Prat, A.1
Parker, J.S.2
Karginova, O.3
-
10
-
-
51349088017
-
Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes
-
Desmedt C, Haibe-Kains B, Wirapati P, et al. Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes. Clin Cancer Res. 2008; 14:5158-5165.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 5158-5165
-
-
Desmedt, C.1
Haibe-Kains, B.2
Wirapati, P.3
-
11
-
-
77953422867
-
PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer
-
USA.
-
Loi S, Haibe-Kains B, Majjaj S, et al. PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer. Proc Natl Acad Sci USA. 2010;107:10208-10213.
-
(2010)
Proc. Natl. Acad. Sci.
, vol.107
, pp. 10208-10213
-
-
Loi, S.1
Haibe-Kains, B.2
Majjaj, S.3
-
12
-
-
77955837344
-
Breast cancer precursors revisited: Molecular features and progression pathways
-
Lopez-Garcia MA, Geyer FC, Lacroix-Triki M, et al. Breast cancer precursors revisited: molecular features and progression pathways. Histopathology. 2010;57:171-192.
-
(2010)
Histopathology
, vol.57
, pp. 171-192
-
-
Lopez-Garcia, M.A.1
Geyer, F.C.2
Lacroix-Triki, M.3
-
13
-
-
58149330982
-
Meta-analysis of gene expression profiles in breast cancer: Toward a unified understanding of breast cancer subtyping and prognosis signatures
-
Wirapati P, Sotiriou C, Kunkel S, et al. Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res. 2008;10:R65.
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Wirapati, P.1
Sotiriou, C.2
Kunkel, S.3
-
14
-
-
78649825336
-
Current and emerging biomarkers in breast cancer: Prognosis and prediction
-
Weigel MT, Dowsett M. Current and emerging biomarkers in breast cancer: prognosis and prediction. Endocr Relat Cancer. 2010;17:R245-R262.
-
(2010)
Endocr. Relat. Cancer
, vol.17
-
-
Weigel, M.T.1
Dowsett, M.2
-
15
-
-
71249163835
-
Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online adjuvant! program: A hospitalbased retrospective cohort study
-
Mook S, Schmidt MK, Rutgers EJ, et al. Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospitalbased retrospective cohort study. Lancet Oncol. 2009;10: 1070-1076.
-
(2009)
Lancet Oncol.
, vol.10
, pp. 1070-1076
-
-
Mook, S.1
Schmidt, M.K.2
Rutgers, E.J.3
-
16
-
-
0035881617
-
Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns
-
Gruvberger S, Ringner M, Chen Y, et al. Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res. 2001;61:5979-5984. (Pubitemid 32762524)
-
(2001)
Cancer Research
, vol.61
, Issue.16
, pp. 5979-5984
-
-
Gruvberger, S.1
Ringner, M.2
Chen, Y.3
Panavally, S.4
Saal, L.H.5
Borg, A.6
Ferno, M.7
Peterson, C.8
Meltzer, P.S.9
-
17
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406:747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
18
-
-
62449131093
-
Supervised risk predictor of breast cancer based on intrinsic subtypes
-
Parker JS, Mullins M, Cheang MC, et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol. 2009;27:1160-1167.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 1160-1167
-
-
Parker, J.S.1
Mullins, M.2
Cheang, M.C.3
-
19
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
DOI 10.1073/pnas.191367098
-
Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA. 2001; 98:10869-10874. (Pubitemid 32878711)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
Hastie, T.7
Eisen, M.B.8
Van De Rijn, M.9
Jeffrey, S.S.10
Thorsen, T.11
Quist, H.12
Matese, J.C.13
Brown, P.O.14
Botstein, D.15
Lonning, P.E.16
Borresen-Dale, A.-L.17
-
20
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
DOI 10.1073/pnas.0932692100
-
Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA. 2003;100:8418-8423. (Pubitemid 36842560)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
Hastie, T.4
Marron, J.S.5
Nobel, A.6
Deng, S.7
Johnsen, H.8
Pesich, R.9
Geisler, S.10
Demeter, J.11
Perou, C.M.12
Lonning, P.E.13
Brown, P.O.14
Borresen-Dale, A.-L.15
Botstein, D.16
-
21
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
-
DOI 10.1073/pnas.1732912100
-
Sotiriou C, Neo SY, McShane LM, et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA. 2003;100:10393-10398. (Pubitemid 37071889)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.18
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.-Y.2
McShane, L.M.3
Korn, E.L.4
Long, P.M.5
Jazaeri, A.6
Martiat, P.7
Fox, S.B.8
Harris, A.L.9
Liu, E.T.10
-
22
-
-
34548863946
-
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
-
Herschkowitz JI, Simin K, Weigman VJ, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol. 2007;8:R76.
-
(2007)
Genome Biol.
, vol.8
-
-
Herschkowitz, J.I.1
Simin, K.2
Weigman, V.J.3
-
23
-
-
81555199640
-
Microarrays in the 2010s: The contribution of microarray-based gene expression profiling to breast cancer classification prognostication and prediction
-
Colombo PE, Milanezi F, Weigelt B, et al. Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction. Breast Cancer Res. 2011;13:212.
-
(2011)
Breast Cancer Res.
, vol.13
, pp. 212
-
-
Colombo, P.E.1
Milanezi, F.2
Weigelt, B.3
-
24
-
-
81555216077
-
Gene expression profiling in breast cancer: Classification prognostication and prediction
-
In press
-
Reis-Filho JS, Pusztai L. Gene expression profiling in breast cancer: classification, prognostication and prediction. Lancet. 2011. (In press.
-
(2011)
Lancet
-
-
Reis-Filho, J.S.1
Pusztai, L.2
-
26
-
-
79955423541
-
Robustness of breast cancer molecular subtypes identification
-
Haibe-Kains B, Culhane A, Desmedt C, et al. Robustness of breast cancer molecular subtypes identification. Ann Oncol. 2010;21:iv49-iv59.
-
(2010)
Ann. Oncol.
, vol.21
-
-
Haibe-Kains, B.1
Culhane, A.2
Desmedt, C.3
-
27
-
-
77950308839
-
Breast cancer molecular profiling with single sample predictors: A retrospective analysis
-
Weigelt B, Mackay A, A'Hern R, et al. Breast cancer molecular profiling with single sample predictors: a retrospective analysis. Lancet Oncol. 2010;11:339-349.
-
(2010)
Lancet Oncol.
, vol.11
, pp. 339-349
-
-
Weigelt, B.1
Mackay, A.2
A'Hern, R.3
-
28
-
-
84655161546
-
Challenges translating breast cancer gene signatures into the clinic
-
10.1038/nrclinonc.2011.125 Epub ahead of print
-
Weigelt B, Pusztai L, Ashworth A, et al. Challenges translating breast cancer gene signatures into the clinic. Nat Rev Clin Oncol. 2011. DOI: 10.1038/nrclinonc.2011.125. [Epub ahead of print].
-
(2011)
Nat. Rev. Clin. Oncol.
-
-
Weigelt, B.1
Pusztai, L.2
Ashworth, A.3
-
29
-
-
33748578365
-
Molecular classification of breast cancer: Limitations and potential
-
DOI 10.1634/theoncologist.11-8-868
-
Pusztai L, Mazouni C, Anderson K, et al. Molecular classification of breast cancer: limitations and potential. Oncologist. 2006;11:868-877. (Pubitemid 44373759)
-
(2006)
Oncologist
, vol.11
, Issue.8
, pp. 868-877
-
-
Pusztai, L.1
Mazouni, C.2
Anderson, K.3
Wu, Y.4
Symmans, W.F.5
-
30
-
-
33845438621
-
Are clusters found in one dataset present in another dataset?
-
DOI 10.1093/biostatistics/kxj029
-
Kapp AV, Tibshirani R. Are clusters found in one dataset present in another dataset? Biostatistics. 2007;8:9-31. (Pubitemid 44906101)
-
(2007)
Biostatistics
, vol.8
, Issue.1
, pp. 9-31
-
-
Kapp, A.V.1
Tibshirani, R.2
-
31
-
-
79955391807
-
Microarray-based class discovery for molecular classification of breast cancer: Analysis of interobserver agreement
-
Mackay A, Weigelt B, Grigoriadis A, et al. Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement. J Natl Cancer Inst. 2011;103:662-673.
-
(2011)
J. Natl. Cancer Inst.
, vol.103
, pp. 662-673
-
-
Mackay, A.1
Weigelt, B.2
Grigoriadis, A.3
-
32
-
-
38449122135
-
Challenges in projecting clustering results across gene expression-profiling datasets
-
DOI 10.1093/jnci/djm216
-
Lusa L, McShane LM, Reid JF, et al. Challenges in projecting clustering results across gene expression-profiling datasets. J Natl Cancer Inst. 2007;99:1715-1723. (Pubitemid 351767219)
-
(2007)
Journal of the National Cancer Institute
, vol.99
, Issue.22
, pp. 1715-1723
-
-
Lusa, L.1
McShane, L.M.2
Reid, J.F.3
De Cecco, L.4
Ambrogi, F.5
Biganzoli, E.6
Gariboldi, M.7
Pierotti, M.A.8
-
33
-
-
20144386127
-
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
-
DOI 10.1073/pnas.0409462102
-
Chang HY, Nuyten DS, Sneddon JB, et al. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci USA. 2005;102:3738-3743. (Pubitemid 40354681)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.10
, pp. 3738-3743
-
-
Chang, H.Y.1
Nuyten, D.S.A.2
Sneddon, J.B.3
Hastie, T.4
Tibshirani, R.5
Sorlie, T.6
Dai, H.7
He, Y.D.8
Van'T Veer, L.J.9
Bartelink, H.10
Van De Rijn, M.11
Brown, P.O.12
Van De Vijver, M.J.13
-
34
-
-
33746910265
-
Concordance among gene-expression-based predictors for breast cancer
-
DOI 10.1056/NEJMoa052933
-
Fan C, Oh DS, Wessels L, et al. Concordance among geneexpression- based predictors for breast cancer. N Engl J Med. 2006;355:560-569. (Pubitemid 44200649)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.6
, pp. 560-569
-
-
Fan, C.1
Oh, D.S.2
Wessels, L.3
Weigelt, B.4
Nuyten, D.S.A.5
Nobel, A.B.6
Van't Veer, L.J.7
Perou, C.M.8
-
35
-
-
63849148854
-
A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation immune response and RNA splicing modules in breast cancer
-
Reyal F, van Vliet MH, Armstrong NJ, et al. A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer. Breast Cancer Res. 2008;10:R93.
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Reyal, F.1
Van Vliet, M.H.2
Armstrong, N.J.3
-
36
-
-
78049453780
-
A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptorpositive breast cancer
-
Nielsen TO, Parker JS, Leung S, et al. A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptorpositive breast cancer. Clin Cancer Res. 2010;16:5222-5232.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 5222-5232
-
-
Nielsen, T.O.1
Parker, J.S.2
Leung, S.3
-
37
-
-
33745445353
-
The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis
-
Cleator SJ, Powles TJ, Dexter T, et al. The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis. Breast Cancer Res. 2006;8:R32.
-
(2006)
Breast Cancer Res.
, vol.8
-
-
Cleator, S.J.1
Powles, T.J.2
Dexter, T.3
-
38
-
-
79959654839
-
Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples
-
Elloumi F, Hu Z, Li Y, et al. Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples. BMC Med Genomics. 2011;4:54.
-
(2011)
BMC Med. Genomics
, vol.4
, pp. 54
-
-
Elloumi, F.1
Hu, Z.2
Li, Y.3
-
39
-
-
33744960226
-
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
-
DOI 10.1001/jama.295.21.2492
-
Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA. 2006;295:2492-2502. (Pubitemid 43854964)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.21
, pp. 2492-2502
-
-
Carey, L.A.1
Perou, C.M.2
Livasy, C.A.3
Dressler, L.G.4
Cowan, D.5
Conway, K.6
Karaca, G.7
Troester, M.A.8
Chiu, K.T.9
Edmiston, S.10
Deming, S.L.11
Geradts, J.12
Cheang, M.C.U.13
Nielsen, T.O.14
Moorman, P.G.15
Earp, H.S.16
Millikan, R.C.17
-
40
-
-
66849140730
-
Ki67 index HER2 status and prognosis of patients with luminal B breast cancer
-
Cheang MC, Chia SK, Voduc D, et al. Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst. 2009;101:736-750.
-
(2009)
J. Natl. Cancer Inst.
, vol.101
, pp. 736-750
-
-
Cheang, M.C.1
Chia, S.K.2
Voduc, D.3
-
41
-
-
79960980007
-
Strategies for subtypes-dealing with the diversity of breast cancer: Highlights of the St gallen international expert consensus on the primary therapy of early breast cancer 2011
-
Goldhirsch A, Wood WC, Coates AS, et al. Strategies for subtypes-dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011. Ann Oncol. 2011;22:1736-1747.
-
(2011)
Ann. Oncol.
, vol.22
, pp. 1736-1747
-
-
Goldhirsch, A.1
Wood, W.C.2
Coates, A.S.3
-
42
-
-
40949121882
-
Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
-
DOI 10.1158/1078-0432.CCR-07-1658
-
Cheang MC, Voduc D, Bajdik C, et al. Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res. 2008; 14:1368-1376. (Pubitemid 351413917)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.5
, pp. 1368-1376
-
-
Cheang, M.C.U.1
Voduc, D.2
Bajdik, C.3
Leung, S.4
McKinney, S.5
Chia, S.K.6
Perou, C.M.7
Nielsen, T.O.8
-
43
-
-
4143150688
-
Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
-
DOI 10.1158/1078-0432.CCR-04-0220
-
Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004;10: 5367-5374. (Pubitemid 39100473)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.16
, pp. 5367-5374
-
-
Nielsen, T.O.1
Hsu, F.D.2
Jensen, K.3
Cheang, M.4
Karaca, G.5
Hu, Z.6
Hernandez-Boussard, T.7
Livasy, C.8
Cowan, D.9
Dressler, L.10
Akslen, L.A.11
Ragaz, J.12
Gown, A.M.13
Gilks, C.B.14
Van De Rijn, M.15
Perou, C.M.16
-
44
-
-
79958766471
-
Association between breast cancer subtypes and response to neoadjuvant anastrozole
-
Dunbier AK, Anderson H, Ghazoui Z, et al. Association between breast cancer subtypes and response to neoadjuvant anastrozole. Steroids. 2011;76:736-740.
-
(2011)
Steroids
, vol.76
, pp. 736-740
-
-
Dunbier, A.K.1
Anderson, H.2
Ghazoui, Z.3
-
45
-
-
79959268722
-
Randomized phase II neoadjuvant comparison between letrozole anastrozole and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: Clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype-ACOSOG Z1031
-
Ellis MJ, Suman VJ, Hoog J, et al. Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor- rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype-ACOSOG Z1031. J Clin Oncol. 2011; 29:2342-2349.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 2342-2349
-
-
Ellis, M.J.1
Suman, V.J.2
Hoog, J.3
-
46
-
-
82455164239
-
First generation prognostic gene signatures for breast cancer predict both survival and chemotherapy sensitivity and identify overlapping patient populations
-
Iwamoto T, Lee JS, Bianchini G, et al. First generation prognostic gene signatures for breast cancer predict both survival and chemotherapy sensitivity and identify overlapping patient populations. Breast Cancer Res Treat. 2011; 130:155-164.
-
(2011)
Breast Cancer Res. Treat
, vol.130
, pp. 155-164
-
-
Iwamoto, T.1
Lee, J.S.2
Bianchini, G.3
-
47
-
-
67649983962
-
Ki67 expression and docetaxel efficacy in patients with estrogen receptorpositive breast cancer
-
Penault-Llorca F, Andre F, Sagan C, et al. Ki67 expression and docetaxel efficacy in patients with estrogen receptorpositive breast cancer. J Clin Oncol. 2009;27:2809-2815.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 2809-2815
-
-
Penault-Llorca, F.1
Andre, F.2
Sagan, C.3
-
48
-
-
84857782927
-
A refined molecular taxonomy of breast cancer
-
Jul 25 10.1038/onc.2011.301. Epub ahead of print
-
Guedj M, Marisa L, de Reynies A, et al. A refined molecular taxonomy of breast cancer. Oncogene. 2011. Jul 25. Doi: 10.1038/onc.2011.301. [Epub ahead of print].
-
(2011)
Oncogene
-
-
Guedj, M.1
Marisa, L.2
De Reynies, A.3
-
49
-
-
37849041082
-
Molecular subtypes in breast cancer evaluation and management: Divide and conquer
-
Peppercorn J, Perou CM, Carey LA. Molecular subtypes in breast cancer evaluation and management: divide and conquer. Cancer Invest. 2008;26:1-10.
-
(2008)
Cancer Invest.
, vol.26
, pp. 1-10
-
-
Peppercorn, J.1
Perou, C.M.2
Carey, L.A.3
-
50
-
-
29144475553
-
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials
-
DOI 10.1016/S0140-6736(05)67887-7, PII S0140673605678877
-
Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;366:2087-2106. (Pubitemid 41797643)
-
(2005)
Lancet
, vol.366
, Issue.9503
, pp. 2087-2106
-
-
Clarke, M.1
Collins, R.2
Darby, S.3
-
51
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
DOI 10.1038/415530a
-
van't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002;415:530-536. (Pubitemid 34130608)
-
(2002)
Nature
, vol.415
, Issue.6871
, pp. 530-536
-
-
Van't Veer, L.J.1
Dai, H.2
Van De Vijver, M.J.3
He, Y.D.4
Hart, A.A.M.5
Mao, M.6
Peterse, H.L.7
Van Der Kooy, K.8
Marton, M.J.9
Witteveen, A.T.10
Schreiber, G.J.11
Kerkhoven, R.M.12
Roberts, C.13
Linsley, P.S.14
Bernards, R.15
Friend, S.H.16
-
52
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
DOI 10.1056/NEJMoa021967
-
van de Vijver MJ, He YD, van't Veer LJ, et al. A geneexpression signature as a predictor of survival in breast cancer. N Engl J Med. 2002;347:1999-2009. (Pubitemid 35461656)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.25
, pp. 1999-2009
-
-
Van De Vijver, M.J.1
He, Y.D.2
Van 'T Veer, L.J.3
Dai, H.4
Hart, A.A.M.5
Voskuil, D.W.6
Schreiber, G.J.7
Peterse, J.L.8
Roberts, C.9
Marton, M.J.10
Parrish, M.11
Atsma, D.12
Witteveen, A.13
Glas, A.14
Delahaye, L.15
Van Der Velde, T.16
Bartelink, H.17
Rodenhuis, S.18
Rutgers, E.T.19
Friend, S.H.20
Bernards, R.21
more..
-
53
-
-
13844310310
-
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
-
DOI 10.1016/S0140-6736(05)17947-1
-
Wang Y, Klijn JG, Zhang Y, et al. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet. 2005;365:671-679. (Pubitemid 40260888)
-
(2005)
Lancet
, vol.365
, Issue.9460
, pp. 671-679
-
-
Wang, Y.1
Klijn, J.G.M.2
Zhang, Y.3
Sieuwerts, A.M.4
Look, M.P.5
Yang, F.6
Talantov, D.7
Timmermans, M.8
Meijer-Van Gelder, M.E.9
Yu, J.10
Jatkoe, T.11
Berns, E.M.J.J.12
Atkins, D.13
Foekens, J.A.14
-
54
-
-
78751696635
-
Predicting prognosis of breast cancer with gene signatures: Are we lost in a sea of data
-
Iwamoto T, Pusztai L. Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data? Genome Med. 2010;2:81.
-
(2010)
Genome Med.
, vol.2
, pp. 81
-
-
Iwamoto, T.1
Pusztai, L.2
-
55
-
-
78650918264
-
Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry
-
Weigelt B, Reis-Filho JS. Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry. Breast Cancer Res. 2010;12(suppl 4):S5.
-
(2010)
Breast Cancer Res.
, vol.12
, Issue.4
-
-
Weigelt, B.1
Reis-Filho, J.S.2
-
56
-
-
80052845090
-
A new molecular predictor of distant recurrence in ER-positive HER2-negative breast cancer adds independent information to conventional clinical risk factors
-
Filipits M, Rudas M, Jakesz R, et al. A new molecular predictor of distant recurrence in ER-positive, HER2- negative breast cancer adds independent information to conventional clinical risk factors. Clin Cancer Res. 2011; 17:6012-6020.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 6012-6020
-
-
Filipits, M.1
Rudas, M.2
Jakesz, R.3
-
57
-
-
67649183386
-
The 70-gene prognosissignature predicts disease outcome in breast cancer patients with 1-3 positive lymph nodes in an independent validation study
-
Mook S, Schmidt MK, Viale G, et al. The 70-gene prognosissignature predicts disease outcome in breast cancer patients with 1-3 positive lymph nodes in an independent validation study. Breast Cancer Res Treat. 2009;116:295-302.
-
(2009)
Breast Cancer Res. Treat.
, vol.116
, pp. 295-302
-
-
Mook, S.1
Schmidt, M.K.2
Viale, G.3
-
58
-
-
77950862535
-
The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age
-
Mook S, Schmidt MK, Weigelt B, et al. The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age. Ann Oncol. 2010; 21:717-722.
-
(2010)
Ann. Oncol.
, vol.21
, pp. 717-722
-
-
Mook, S.1
Schmidt, M.K.2
Weigelt, B.3
-
59
-
-
49649114805
-
Analysis of the mammaprint breast cancer assay in a predominantly postmenopausal cohort
-
Wittner BS, Sgroi DC, Ryan PD, et al. Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort. Clin Cancer Res. 2008;14:2988-2993.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 2988-2993
-
-
Wittner, B.S.1
Sgroi, D.C.2
Ryan, P.D.3
-
60
-
-
77950859892
-
The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer
-
Knauer M, Mook S, Rutgers EJ, et al. The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer. Breast Cancer Res Treat. 2010;120:655-661.
-
(2010)
Breast Cancer Res. Treat.
, vol.120
, pp. 655-661
-
-
Knauer, M.1
Mook, S.2
Rutgers, E.J.3
-
61
-
-
77953565979
-
Gene-expression-based prognostic assays for breast cancer
-
Kim C, Paik S. Gene-expression-based prognostic assays for breast cancer. Nat Rev Clin Oncol. 2010;7:340-347.
-
(2010)
Nat. Rev. Clin. Oncol.
, vol.7
, pp. 340-347
-
-
Kim, C.1
Paik, S.2
-
62
-
-
33144462268
-
Gene expression profiling in breast cancer: Understanding the molecular basis of histologic grade to improve prognosis
-
DOI 10.1093/jnci/djj052
-
Sotiriou C, Wirapati P, Loi S, et al. Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. J Natl Cancer Inst. 2006;98:262-272. (Pubitemid 43264710)
-
(2006)
Journal of the National Cancer Institute
, vol.98
, Issue.4
, pp. 262-272
-
-
Sotiriou, C.1
Wirapati, P.2
Loi, S.3
Harris, A.4
Fox, S.5
Smeds, J.6
Nordgren, H.7
Farmer, P.8
Praz, V.9
Haibe-Kains, B.10
Desmedt, C.11
Larsimont, D.12
Cardoso, F.13
Peterse, H.14
Nuyten, D.15
Buyse, M.16
Van De Vijver, M.J.17
Bergh, J.18
Piccart, M.19
Delorenzi, M.20
more..
-
63
-
-
33751261643
-
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer
-
DOI 10.1158/0008-5472.CAN-05-4414
-
Ivshina AV, George J, Senko O, et al. Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer. Cancer Res. 2006;66:10292-10301. (Pubitemid 44799747)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10292-10301
-
-
Ivshina, A.V.1
George, J.2
Senko, O.3
Mow, B.4
Putti, T.C.5
Smeds, J.6
Lindahl, T.7
Pawitan, Y.8
Hall, P.9
Nordgren, H.10
Wong, J.E.L.11
Liu, E.T.12
Bergh, J.13
Kuznetsov, V.A.14
Miller, L.D.15
-
64
-
-
70350458132
-
Improvement of the clinical applicability of the genomic grade index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues
-
Toussaint J, Sieuwerts AM, Haibe-Kains B, et al. Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues. BMC Genomics. 2009;10:424.
-
(2009)
BMC Genomics
, vol.10
, pp. 424
-
-
Toussaint, J.1
Sieuwerts, A.M.2
Haibe-Kains, B.3
-
65
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
-
DOI 10.1056/NEJMoa041588
-
Paik S, Shak S, Tang G, et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med. 2004;351:2817-2826. (Pubitemid 40051905)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.27
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
Kim, C.4
Baker, J.5
Cronin, M.6
Baehner, F.L.7
Walker, M.G.8
Watson, D.9
Park, T.10
Hiller, W.11
Fisher, E.R.12
Wickerham, D.L.13
Bryant, J.14
Wolmark, N.15
-
66
-
-
33744814477
-
Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer
-
DOI 10.1200/JCO.2005.04.7985
-
Paik S, Tang G, Shak S, et al. Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor- positive breast cancer. J Clin Oncol. 2006;24:3726-3734. (Pubitemid 46622311)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.23
, pp. 3726-3734
-
-
Paik, S.1
Tang, G.2
Shak, S.3
Kim, C.4
Baker, J.5
Kim, W.6
Cronin, M.7
Baehner, F.L.8
Watson, D.9
Bryant, J.10
Costantino, J.P.11
Geyer Jr., C.E.12
Wickerham, D.L.13
Wolmark, N.14
-
67
-
-
33744808550
-
A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients
-
Habel LA, Shak S, Jacobs MK, et al. A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients. Breast Cancer Res. 2006;8:R25.
-
(2006)
Breast Cancer Res.
, vol.8
-
-
Habel, L.A.1
Shak, S.2
Jacobs, M.K.3
-
68
-
-
51649110952
-
Prognostic utility of the 21-gene assay in hormone receptor-positive operable breast cancer compared with classical clinicopathologic features
-
Goldstein LJ, Gray R, Badve S, et al. Prognostic utility of the 21-gene assay in hormone receptor-positive operable breast cancer compared with classical clinicopathologic features. J Clin Oncol. 2008;26:4063-4071.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 4063-4071
-
-
Goldstein, L.J.1
Gray, R.2
Badve, S.3
-
69
-
-
77951637777
-
Prediction of risk of distant recurrence using the 21-gene recurrence score in nodenegative and node-positive postmenopausal patients withbreast cancer treated with anastrozole or tamoxifen: A TransATAC study
-
Dowsett M, Cuzick J, Wale C, et al. Prediction of risk of distant recurrence using the 21-gene recurrence score in nodenegative and node-positive postmenopausal patients withbreast cancer treated with anastrozole or tamoxifen: a TransATAC study. J Clin Oncol. 2010;28:1829-1834.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1829-1834
-
-
Dowsett, M.1
Cuzick, J.2
Wale, C.3
-
70
-
-
28044472321
-
Gene expression profiles in paraffin-embedded core biopsy tissue predict response to chemotherapy in women with locally advanced breast cancer
-
DOI 10.1200/JCO.2005.02.0818
-
Gianni L, Zambetti M, Clark K, et al. Gene expression profiles in paraffin-embedded core biopsy tissue predict response to chemotherapy in women with locally advanced breast cancer. J Clin Oncol. 2005;23:7265-7277. (Pubitemid 46202341)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.29
, pp. 7265-7277
-
-
Gianni, L.1
Zambetti, M.2
Clark, K.3
Baker, J.4
Cronin, M.5
Wu, J.6
Mariani, G.7
Rodriguez, J.8
Carcangiu, M.9
Watson, D.10
Valagussa, P.11
Rouzier, R.12
Symmans, W.F.13
Ross, J.S.14
Hortobagyi, G.N.15
Pusztai, L.16
Shak, S.17
-
71
-
-
73249140371
-
Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive oestrogen-receptor- positive breast cancer on chemotherapy: A retrospective analysis of a randomised trial
-
Albain KS, Barlow WE, Shak S, et al. Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor- positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. Lancet Oncol. 2010;11: 55-65.
-
(2010)
Lancet Oncol.
, vol.11
, pp. 55-65
-
-
Albain, K.S.1
Barlow, W.E.2
Shak, S.3
-
72
-
-
70449420123
-
Use of archived specimens in evaluation of prognostic and predictive biomarkers
-
Simon RM, Paik S, Hayes DF. Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst. 2009;101:1446-1452.
-
(2009)
J. Natl. Cancer Inst.
, vol.101
, pp. 1446-1452
-
-
Simon, R.M.1
Paik, S.2
Hayes, D.F.3
-
73
-
-
36849069347
-
American society of clinical oncology 2007 update of recommendations for the use of tumor markers in breast cancer
-
DOI 10.1200/JCO.2007.14.2364
-
Harris L, Fritsche H, Mennel R, et al. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J Clin Oncol. 2007;25:5287-5312. (Pubitemid 350232263)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.33
, pp. 5287-5312
-
-
Harris, L.1
Fritsche, H.2
Mennel, R.3
Norton, L.4
Ravdin, P.5
Taube, S.6
Somerfield, M.R.7
Hayes, D.F.8
Bast Jr., R.C.9
-
74
-
-
53149133527
-
Refinement of breast cancer classification by molecular characterization of histological special types
-
Weigelt B, Horlings HM, Kreike B, et al. Refinement of breast cancer classification by molecular characterization of histological special types. J Pathol. 2008;216:141-150.
-
(2008)
J. Pathol.
, vol.216
, pp. 141-150
-
-
Weigelt, B.1
Horlings, H.M.2
Kreike, B.3
-
75
-
-
33748693297
-
Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer
-
DOI 10.1093/jnci/djj329
-
Buyse M, Loi S, van't Veer L, et al. Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer. J Natl Cancer Inst. 2006; 98:1183-1192. (Pubitemid 44390989)
-
(2006)
Journal of the National Cancer Institute
, vol.98
, Issue.17
, pp. 1183-1192
-
-
Buyse, M.1
Loi, S.2
Van't Veer, L.3
Viale, G.4
Delorenzi, M.5
Glas, A.M.6
D'Assignies, M.S.7
Bergh, J.8
Lidereau, R.9
Ellis, P.10
Harris, A.11
Bogaerts, J.12
Therasse, P.13
Floore, A.14
Amakrane, M.15
Piette, F.16
Rutgers, E.17
Sotiriou, C.18
Cardoso, F.19
Piccart, M.J.20
Decker, N.21
Straehle, C.22
more..
-
76
-
-
34250652449
-
Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series
-
DOI 10.1158/1078-0432.CCR-06-2765
-
Desmedt C, Piette F, Loi S, et al. Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res. 2007;13:3207-3214. (Pubitemid 46944903)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.11
, pp. 3207-3214
-
-
Desmedt, C.1
Piette, F.2
Loi, S.3
Wang, Y.4
Lallemand, F.5
Haibe-Kains, B.6
Viale, G.7
Delorenzi, M.8
Zhang, Y.9
D'Assignies, M.S.10
Bergh, J.11
Lidereau, R.12
Ellis, P.13
Harris, A.L.14
Klijn, J.G.M.15
Foekens, J.A.16
Cardoso, F.17
Piccart, M.J.18
Buyse, M.19
Sotiriou, C.20
more..
-
77
-
-
81155133281
-
Prognostic value of a combined estrogen receptor progesterone receptor Ki-67 and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the genomic health recurrence score in early breast cancer
-
Cuzick J, Dowsett M, Pineda S, et al. Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health Recurrence Score in early breast cancer. J Clin Oncol. 2011; 29:4273-4278.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4273-4278
-
-
Cuzick, J.1
Dowsett, M.2
Pineda, S.3
-
78
-
-
33846965616
-
Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer
-
Dowsett M, Smith IE, Ebbs SR, et al. Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer. J Natl Cancer Inst. 2007; 99:167-170.
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 167-170
-
-
Dowsett, M.1
Smith, I.E.2
Ebbs, S.R.3
-
79
-
-
81555208345
-
Assessment of Ki67 in breast cancer: Recommendations from the international Ki67 in breast cancer working group
-
Dowsett M, Nielsen TO, A'Hern R, et al. Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer Working Group. J Natl Cancer Inst. 2011;103:1656-1664.
-
(2011)
J. Natl. Cancer Inst.
, vol.103
, pp. 1656-1664
-
-
Dowsett, M.1
Nielsen, T.O.2
A'Hern, R.3
-
80
-
-
38949202980
-
Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
-
DOI 10.1002/path.2278
-
Bergamaschi A, Tagliabue E, Sorlie T, et al. Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome. J Pathol. 2008;214:357-367. (Pubitemid 351212391)
-
(2008)
Journal of Pathology
, vol.214
, Issue.3
, pp. 357-367
-
-
Bergamaschi, A.1
Tagliabue, E.2
Sorlie, T.3
Naume, B.4
Triulzi, T.5
Orlandi, R.6
Russnes, H.G.7
Nesland, J.M.8
Tammi, R.9
Auvinen, P.10
Kosma, V.-M.11
Menard, S.12
Borresen-Dale, A.-L.13
-
81
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
DOI 10.1038/nm1764, PII NM1764
-
Finak G, Bertos N, Pepin F, et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat Med. 2008; 14:518-527. (Pubitemid 351655218)
-
(2008)
Nature Medicine
, vol.14
, Issue.5
, pp. 518-527
-
-
Finak, G.1
Bertos, N.2
Pepin, F.3
Sadekova, S.4
Souleimanova, M.5
Zhao, H.6
Chen, H.7
Omeroglu, G.8
Meterissian, S.9
Omeroglu, A.10
Hallett, M.11
Park, M.12
-
82
-
-
63349091533
-
A robust classifier of high predictive value to identify good prognosis patients in ERnegative breast cancer
-
Teschendorff AE, Caldas C. A robust classifier of high predictive value to identify good prognosis patients in ERnegative breast cancer. Breast Cancer Res. 2008;10:R73.
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Teschendorff, A.E.1
Caldas, C.2
-
83
-
-
77957759237
-
A multigene predictor of metastatic outcome in early stage hormone receptornegative and triple-negative breast cancer
-
Yau C, Esserman L, Moore DH, et al. A multigene predictor of metastatic outcome in early stage hormone receptornegative and triple-negative breast cancer. Breast Cancer Res. 2010;12:R85.
-
(2010)
Breast Cancer Res.
, vol.12
-
-
Yau, C.1
Esserman, L.2
Moore, D.H.3
-
84
-
-
84859111188
-
A prognostic model for lymph node-negative breast cancer patients based on the integration of proliferation and immunity
-
Jun 11. 10.1007/s10549-011-1626-8 Epub ahead of print
-
Oh E, Choi YL, Park T, et al. A prognostic model for lymph node-negative breast cancer patients based on the integration of proliferation and immunity. Breast Cancer Res Treat. 2011. Jun 11. DOI: 10.1007/s10549-011-1626-8 [Epub ahead of print].
-
(2011)
Breast Cancer Res. Treat.
-
-
Oh, E.1
Choi, Y.L.2
Park, T.3
-
85
-
-
78049437767
-
Molecular anatomy of breast cancer stroma and its prognostic value in estrogen receptor-positive and -negative cancers
-
Bianchini G, Qi Y, Alvarez RH, et al. Molecular anatomy of breast cancer stroma and its prognostic value in estrogen receptor-positive and -negative cancers. J Clin Oncol. 2010;28:4316-4323.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 4316-4323
-
-
Bianchini, G.1
Qi, Y.2
Alvarez, R.H.3
-
86
-
-
79956329617
-
Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer
-
Mahmoud SM, Paish EC, Powe DG, et al. Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer. J Clin Oncol. 2011;29:1949-1955.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 1949-1955
-
-
Mahmoud, S.M.1
Paish, E.C.2
Powe, D.G.3
-
87
-
-
84865191854
-
Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer
-
May 12. 10.1007/s10549-011-1554-7 Epub ahead of print
-
Ono M, Tsuda H, Shimizu C, et al. Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer. Breast Cancer Res Treat. 2011. May 12. DOI: 10.1007/s10549-011-1554-7 [Epub ahead of print].
-
(2011)
Breast Cancer Res. Treat.
-
-
Ono, M.1
Tsuda, H.2
Shimizu, C.3
-
88
-
-
67650327607
-
Genomic grade index is associated with response to chemotherapy in patients with breast cancer
-
Liedtke C, Hatzis C, Symmans WF, et al. Genomic grade index is associated with response to chemotherapy in patients with breast cancer. J Clin Oncol. 2009;27:3185-3191.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 3185-3191
-
-
Liedtke, C.1
Hatzis, C.2
Symmans, W.F.3
-
89
-
-
77957935139
-
Genomic index of sensitivity to endocrine therapy for breast cancer
-
Symmans WF, Hatzis C, Sotiriou C, et al. Genomic index of sensitivity to endocrine therapy for breast cancer. J Clin Oncol. 2010;28:4111-4119.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 4111-4119
-
-
Symmans, W.F.1
Hatzis, C.2
Sotiriou, C.3
-
90
-
-
65249138229
-
Tiling path genomic profiling of grade 3 invasive ductal breast cancers
-
Natrajan R, Lambros MB, Rodriguez-Pinilla SM, et al. Tiling path genomic profiling of grade 3 invasive ductal breast cancers. Clin Cancer Res. 2009;15:2711-2722.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 2711-2722
-
-
Natrajan, R.1
Lambros, M.B.2
Rodriguez-Pinilla, S.M.3
-
91
-
-
77953123909
-
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like HER2 and luminal cancers
-
Natrajan R, Weigelt B, Mackay A, et al. An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers. Breast Cancer Res Treat. 2010;121:575-589.
-
(2010)
Breast Cancer Res Treat.
, vol.121
, pp. 575-589
-
-
Natrajan, R.1
Weigelt, B.2
Mackay, A.3
-
92
-
-
59449094654
-
Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array
-
Andre F, Job B, Dessen P, et al. Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array. Clin Cancer Res. 2009;15:441-451.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 441-451
-
-
Andre, F.1
Job, B.2
Dessen, P.3
-
93
-
-
39749108733
-
Highresolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer
-
Chin SF, Teschendorff AE, Marioni JC, et al. Highresolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer. Genome Biol. 2007;8:R215.
-
(2007)
Genome Biol.
, vol.8
-
-
Chin, S.F.1
Teschendorff, A..E.2
Marioni, J.C.3
-
94
-
-
33845191779
-
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
-
DOI 10.1016/j.ccr.2006.10.009, PII S1535610806003151
-
Chin K, DeVries S, Fridlyand J, et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell. 2006;10:529-541. (Pubitemid 44854748)
-
(2006)
Cancer Cell
, vol.10
, Issue.6
, pp. 529-541
-
-
Chin, K.1
DeVries, S.2
Fridlyand, J.3
Spellman, P.T.4
Roydasgupta, R.5
Kuo, W.-L.6
Lapuk, A.7
Neve, R.M.8
Qian, Z.9
Ryder, T.10
Chen, F.11
Feiler, H.12
Tokuyasu, T.13
Kingsley, C.14
Dairkee, S.15
Meng, Z.16
Chew, K.17
Pinkel, D.18
Jain, A.19
Ljung, B.M.20
Esserman, L.21
Albertson, D.G.22
Waldman, F.M.23
Gray, J.W.24
more..
-
95
-
-
78149477701
-
Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics
-
Jonsson G, Staaf J, Vallon-Christersson J, et al. Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics. Breast Cancer Res. 2010;12:R42.
-
(2010)
Breast Cancer Res.
, vol.12
-
-
Jonsson, G.1
Staaf, J.2
Vallon-Christersson, J.3
-
96
-
-
78650028237
-
The molecular pathology of breast cancer progression
-
Bombonati A, Sgroi DC. The molecular pathology of breast cancer progression. J Pathol. 2011;223:307-317.
-
(2011)
J. Pathol.
, vol.223
, pp. 307-317
-
-
Bombonati, A.1
Sgroi, D.C.2
-
97
-
-
0031736180
-
Highly recurrent der(1; 16)(q10;p10) and other 16q arm alterations in lobular breast cancer
-
DOI 10.1002/(SICI)1098-2264(199812)23:4<300::AID-GCC4>3.0.CO;2-N
-
Flagiello D, Gerbault-Seureau M, Sastre-Garau X, et al. Highly recurrent der(1;16)(q10;p10) and other 16q arm alterations in lobular breast cancer. Genes Chromosomes Cancer. 1998;23:300-306. (Pubitemid 28507369)
-
(1998)
Genes Chromosomes and Cancer
, vol.23
, Issue.4
, pp. 300-306
-
-
Flagiello, D.1
Gerbault-Seureau, M.2
Sastre-Garau, X.3
Padoy, E.4
Vielh, P.5
Dutrillaux, B.6
-
98
-
-
0032889648
-
Der(16)t(1;16)/der(1;16) in breast cancer detected by fluorescence in situ hybridization is an indicator of better patient prognosis
-
DOI 10.1002/(SICI)1098-2264(199901)24:1<72::AID-GCC10>3.0.CO;2-M
-
Tsuda H, Takarabe T, Fukutomi T, et al. der(16)t(1;16)/ der(1;16) in breast cancer detected by fluorescence in situ hybridization is an indicator of better patient prognosis. Genes Chromosomes Cancer. 1999;24:72-77. (Pubitemid 28544465)
-
(1999)
Genes Chromosomes and Cancer
, vol.24
, Issue.1
, pp. 72-77
-
-
Tsuda, H.1
Takarabe, T.2
Fukutomi, T.3
Hirohashi, S.4
-
99
-
-
79960988896
-
To DNA or not to DNA that is the question when it comes to molecular subtyping for the clinic!
-
Smeets SJ, Harjes U, van Wieringen WN, et al. To DNA or not to DNA? That is the question, when it comes to molecular subtyping for the clinic! Clin Cancer Res. 2011; 17:4959-4964.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 4959-4964
-
-
Smeets, S.J.1
Harjes, U.2
Van Wieringen, W.N.3
-
100
-
-
33748939380
-
Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
-
DOI 10.1002/gcc.20366
-
Bergamaschi A, Kim YH, Wang P, et al. Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer. Genes Chromosomes Cancer. 2006;45: 1033-1040. (Pubitemid 44435537)
-
(2006)
Genes Chromosomes and Cancer
, vol.45
, Issue.11
, pp. 1033-1040
-
-
Bergamaschi, A.1
Kim, Y.H.2
Wang, P.3
Sorlie, T.4
Hernandez-Boussard, T.5
Lonning, P.E.6
Tibshirani, R.7
Borresen-Dale, A.-L.8
Pollack, J.R.9
-
101
-
-
79952198073
-
A prognostic DNA signature for T1T2 node-negative breast cancer patients
-
Gravier E, Pierron G, Vincent-Salomon A, et al. A prognostic DNA signature for T1T2 node-negative breast cancer patients. Genes Chromosomes Cancer. 2010;49:1125-1134.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 1125-1134
-
-
Gravier, E.1
Pierron, G.2
Vincent-Salomon, A.3
-
102
-
-
51049118140
-
An integrative genomic and proteomic analysis of PIK3CA PTEN and AKT mutations in breast cancer
-
Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, et al. An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. Cancer Res. 2008;68:6084-6091.
-
(2008)
Cancer Res.
, vol.68
, pp. 6084-6091
-
-
Stemke-Hale, K.1
Gonzalez-Angulo, A.M.2
Lluch, A.3
-
103
-
-
0036632368
-
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
-
Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer. 2002;2: 489-501. (Pubitemid 37328931)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.7
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
104
-
-
81755162797
-
Phosphatidylinositol 3-kinase and antiestrogen resistance in breast cancer
-
Miller TW, Balko JM, Arteaga CL. Phosphatidylinositol 3-kinase and antiestrogen resistance in breast cancer. J Clin Oncol. 2011;29:4452-4461.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4452-4461
-
-
Miller, T.W.1
Balko, J.M.2
Arteaga, C.L.3
-
105
-
-
79959508436
-
Targeting the phosphoinositide-3 PI3 kinase pathway in breast cancer
-
Baselga J. Targeting the phosphoinositide-3 (PI3) kinase pathway in breast cancer. Oncologist. 2011;16(suppl 1): 12-19.
-
(2011)
Oncologist
, vol.16
, Issue.1
, pp. 12-19
-
-
Baselga, J.1
-
106
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
DOI 10.1158/0008-5472.CAN-04-2933
-
Campbell IG, Russell SE, Choong DY, et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res. 2004;64:7678-7681. (Pubitemid 39446895)
-
(2004)
Cancer Research
, vol.64
, Issue.21
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.H.3
Montgomery, K.G.4
Ciavarella, M.L.5
Hooi, C.S.F.6
Cristiano, B.E.7
Pearson, R.B.8
Phillips, W.A.9
-
107
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
DOI 10.1126/science.1096502
-
Samuels Y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science. 2004;304:554. (Pubitemid 38541907)
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Yan, H.7
Gazdar, A.8
Powell, S.M.9
Riggins, G.J.10
Willson, J.K.V.11
Markowitz, S.12
Kinzler, K.W.13
Vogelstein, B.14
Velculescu, V.E.15
-
108
-
-
16644393213
-
The PIK3CA gene is mutated with high frequency in human breast cancers
-
Bachman KE, Argani P, Samuels Y, et al. The PIK3CA gene is mutated with high frequency in human breast cancers. Cancer Biol Ther. 2004;3:772-775. (Pubitemid 41351083)
-
(2004)
Cancer Biology and Therapy
, vol.3
, Issue.8
, pp. 772-775
-
-
Bachman, K.E.1
Argani, P.2
Samuels, Y.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Konishi, H.7
Karakas, B.8
Blair, B.G.9
Lin, C.10
Peters, B.A.11
Velculescu, V.E.12
Park, B.H.13
-
109
-
-
48949119513
-
PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer
-
Liedtke C, Cardone L, Tordai A, et al. PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer. Breast Cancer Res. 2008;10:R27.
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Liedtke, C.1
Cardone, L.2
Tordai, A.3
-
110
-
-
20144387695
-
PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma
-
DOI 10.1158/0008-5472-CAN-04-3913
-
Saal LH, Holm K, Maurer M, et al. PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. Cancer Res. 2005;65:2554-2559. (Pubitemid 40490050)
-
(2005)
Cancer Research
, vol.65
, Issue.7
, pp. 2554-2559
-
-
Saal, L.H.1
Holm, K.2
Maurer, M.3
Memeo, L.4
Su, T.5
Wang, X.6
Yu, J.S.7
Malmstrom, P.-O.8
Mansukhani, M.9
Enoksson, J.10
Hibshoosh, H.11
Borg, A.12
Parsons, R.13
-
111
-
-
34250749822
-
PIK3CA mutations and PTEN loss correlate with similar prognostic factors and are not mutually exclusive in breast cancer
-
DOI 10.1158/1078-0432.CCR-06-1609
-
Perez-Tenorio G, Alkhori L, Olsson B, et al. PIK3CA mutations and PTEN loss correlate with similar prognostic factors and are not mutually exclusive in breast cancer. Clin Cancer Res. 2007;13:3577-3584. (Pubitemid 46955118)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.12
, pp. 3577-3584
-
-
Perez-Tenorio, G.1
Alkhori, L.2
Olsson, B.3
Waltersson, M.A.4
Nordenskjold, B.5
Rutqvist, L.E.6
Skoog, L.7
Stal, O.8
-
112
-
-
33947230755
-
Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines
-
DOI 10.1158/1541-7786.MCR-06-0263
-
Hollestelle A, Elstrodt F, Nagel JH, et al. Phosphatidylinositol- 3-OH kinase or RAS pathway mutations in human breast cancer cell lines. Mol Cancer Res. 2007;5:195-201. (Pubitemid 46424000)
-
(2007)
Molecular Cancer Research
, vol.5
, Issue.2
, pp. 195-201
-
-
Hollestelle, A.1
Elstrodt, F.2
Nagel, J.H.A.3
Kallemeijn, W.W.4
Schutte, M.5
-
113
-
-
74849112055
-
Phosphatidyl-inositol-3-kinase alpha catalytic subunit mutation and response to neoadjuvant endocrine therapy for estrogen receptor positive breast cancer
-
Ellis MJ, Lin L, Crowder R, et al. Phosphatidyl-inositol-3- kinase alpha catalytic subunit mutation and response to neoadjuvant endocrine therapy for estrogen receptor positive breast cancer. Breast Cancer Res Treat. 2010;119:379-390.
-
(2010)
Breast Cancer Res. Treat.
, vol.119
, pp. 379-390
-
-
Ellis, M.J.1
Lin, L.2
Crowder, R.3
-
114
-
-
79960732694
-
PIK3CA mutation but not PTEN loss of function determines the sensitivity of breast cancer cells to mTOR inhibitory drugs
-
Weigelt B,Warne PH. Downward J. PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs. Oncogene. 2011;30:3222-3233.
-
(2011)
Oncogene
, vol.30
, pp. 3222-3233
-
-
Weigelt, B.1
Warne, P.H.2
Downward, J.3
-
116
-
-
69349105634
-
PIK3CA mutation associates with improved outcome in breast cancer
-
Kalinsky K, Jacks LM, Heguy A, et al. PIK3CA mutation associates with improved outcome in breast cancer. Clin Cancer Res. 2009;15:5049-5059.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5049-5059
-
-
Kalinsky, K.1
Jacks, L.M.2
Heguy, A.3
-
117
-
-
29644444566
-
Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines
-
DOI 10.1016/j.bbrc.2005.12.025, PII S0006291X05027592
-
Whyte DB, Holbeck SL. Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines. Biochem Biophys Res Commun. 2006;340:469-475. (Pubitemid 43021772)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.340
, Issue.2
, pp. 469-475
-
-
Whyte, D.B.1
Holbeck, S.L.2
-
118
-
-
34250687198
-
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity
-
DOI 10.1073/pnas.0702507104
-
Saal LH, Johansson P, Holm K, et al. Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. Proc Natl Acad Sci USA. 2007;104:7564-7569. (Pubitemid 47185946)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.18
, pp. 7564-7569
-
-
Saal, L.H.1
Johansson, P.2
Holm, K.3
Gruvberger-Saal, S.K.4
She, Q.-B.5
Maurer, M.6
Koujak, S.7
Ferrando, A.A.8
Malmstrom, P.9
Memeo, L.10
Isola, J.11
Bendahl, P.-O.12
Rosen, N.13
Hibshoosh, H.14
Ringner, M.15
Borg, A.16
Parsons, R.17
-
119
-
-
4544223402
-
The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome
-
DOI 10.1002/path.1611
-
Panigrahi AR, Pinder SE, Chan SY, et al. The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome. J Pathol. 2004;204:93-100. (Pubitemid 39214486)
-
(2004)
Journal of Pathology
, vol.204
, Issue.1
, pp. 93-100
-
-
Panigrahi, A.R.1
Pinder, S.E.2
Chan, S.Y.3
Paish, E.C.4
Robertson, J.F.R.5
Ellis, I.O.6
-
120
-
-
0032857217
-
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast
-
Perren A, Weng LP, Boag AH, et al. Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast. Am J Pathol. 1999;155: 1253-1260. (Pubitemid 29488932)
-
(1999)
American Journal of Pathology
, vol.155
, Issue.4
, pp. 1253-1260
-
-
Perren, A.1
Weng, L.-P.2
Boag, A.H.3
Ziebold, U.4
Thakore, K.5
Dahia, P.L.M.6
Komminoth, P.7
Lees, J.A.8
Mulligan, L.M.9
Mutter, G.L.10
Eng, C.11
-
121
-
-
0034920457
-
Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer
-
DOI 10.1038/modpathol.3880371
-
Depowski PL, Rosenthal SI, Ross JS. Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer. Mod Pathol. 2001;14:672-676. (Pubitemid 32667211)
-
(2001)
Modern Pathology
, vol.14
, Issue.7
, pp. 672-676
-
-
Depowski, P.L.1
Rosenthal, S.I.2
Ross, J.S.3
-
122
-
-
63849329936
-
Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells
-
Marty B, Maire V, Gravier E, et al. Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells. Breast Cancer Res. 2008;10:R101.
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Marty, B.1
Maire, V.2
Gravier, E.3
-
123
-
-
13244259196
-
Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen
-
DOI 10.1038/modpathol.3800296
-
Shoman N, Klassen S, McFadden A, et al. Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen. Mod Pathol. 2005;18:250-259. (Pubitemid 40188633)
-
(2005)
Modern Pathology
, vol.18
, Issue.2
, pp. 250-259
-
-
Shoman, N.1
Klassen, S.2
McFadden, A.3
Bickis, M.G.4
Torlakovic, E.5
Chibbar, R.6
-
124
-
-
12144269500
-
Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer
-
Osborne CK, Shou J, Massarweh S, et al. Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer. Clin Cancer Res. 2005;11:865s-870ss.
-
(2005)
Clin. Cancer Res.
, vol.11
-
-
Osborne, C.K.1
Shou, J.2
Massarweh, S.3
-
125
-
-
67651174555
-
Gene expression profiling identifies activated growth factor signaling in poor prognosis luminal-B estrogen receptor positive breast cancer
-
Loi S, Sotiriou C, Haibe-Kains B, et al. Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer. BMC Med Genomics. 2009;2:37.
-
(2009)
BMC Med. Genomics
, vol.2
, pp. 37
-
-
Loi, S.1
Sotiriou, C.2
Haibe-Kains, B.3
-
126
-
-
79958728268
-
PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer
-
Gonzalez-Angulo AM, Ferrer-Lozano J, Stemke-Hale K, et al. PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer. Mol Cancer Ther. 2011;10:1093-1101.
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 1093-1101
-
-
Gonzalez-Angulo, A.M.1
Ferrer-Lozano, J.2
Stemke-Hale, K.3
-
127
-
-
80054921787
-
Changes in breast cancer biomarkers in the IGF1R/PI3K pathway in recurrent breast cancer after tamoxifen treatment
-
Drury SC, Detre S, Leary A, et al. Changes in breast cancer biomarkers in the IGF1R/PI3K pathway in recurrent breast cancer after tamoxifen treatment. Endocr Relat Cancer. 2011; 18:565-577.
-
(2011)
Endocr. Relat. Cancer
, vol.18
, pp. 565-577
-
-
Drury, S.C.1
Detre, S.2
Leary, A.3
-
128
-
-
67649382929
-
AKTindependent signaling downstream of oncogenic PIK3CA mutations in human cancer
-
Vasudevan KM. Barbie DA, Davies MA, et al. AKTindependent signaling downstream of oncogenic PIK3CA mutations in human cancer. Cancer Cell. 2009;16:21-32.
-
(2009)
Cancer Cell
, vol.16
, pp. 21-32
-
-
Vasudevan, K.M.1
Barbie, D.A.2
Davies, M.A.3
-
129
-
-
63749129788
-
PI3K and mTOR inhibitors: A new generation of targeted anticancer agents
-
Brachmann S, Fritsch C, Maira SM, et al. PI3K and mTOR inhibitors: a new generation of targeted anticancer agents. Curr Opin Cell Biol. 2009;21:194-198.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 194-198
-
-
Brachmann, S.1
Fritsch, C.2
Maira, S.M.3
-
130
-
-
79955983369
-
The selective class I PI3K inhibitor CH5132799 targets human cancers harboring oncogenic PIK3CA mutations
-
Tanaka H, Yoshida M, Tanimura H, et al. The selective class I PI3K inhibitor CH5132799 targets human cancers harboring oncogenic PIK3CA mutations. Clin Cancer Res. 2011; 17:3272-3281.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 3272-3281
-
-
Tanaka, H.1
Yoshida, M.2
Tanimura, H.3
-
131
-
-
79959327886
-
Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase PI3K inhibitors
-
Shuttleworth SJ, Silva FA, Cecil AR, et al. Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase (PI3K) inhibitors. Curr Med Chem. 2011;18:2686-2714.
-
(2011)
Curr. Med. Chem.
, vol.18
, pp. 2686-2714
-
-
Shuttleworth, S.J.1
Silva, F.A.2
Cecil, A.R.3
-
132
-
-
78650984926
-
Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab
-
Andre F, Campone M, O'Regan R, et al. Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab. J Clin Oncol. 2010;28:5110-5115.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 5110-5115
-
-
Andre, F.1
Campone, M.2
O'Regan, R.3
-
133
-
-
37149020235
-
The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: Results of a phase I study with pharmacokinetics
-
DOI 10.1016/j.ejca.2007.10.003, PII S0959804907007939
-
Awada A, Cardoso F, Fontaine C, et al. The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics. Eur J Cancer. 2008; 44:84-91. (Pubitemid 350256937)
-
(2008)
European Journal of Cancer
, vol.44
, Issue.1
, pp. 84-91
-
-
Awada, A.1
Cardoso, F.2
Fontaine, C.3
Dirix, L.4
De Greve, J.5
Sotiriou, C.6
Steinseifer, J.7
Wouters, C.8
Tanaka, C.9
Zoellner, U.10
Tang, P.11
Piccart, M.12
-
134
-
-
23944439945
-
Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer
-
DOI 10.1200/JCO.2005.66.130
-
Chan S, Scheulen ME, Johnston S, et al. Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer. J Clin Oncol. 2005;23:5314-5322. (Pubitemid 46206985)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.23
, pp. 5314-5322
-
-
Chan, S.1
Scheulen, M.E.2
Johnston, S.3
Mross, K.4
Cardoso, F.5
Dittrich, C.6
Eiermann, W.7
Hess, D.8
Morant, R.9
Semiglazov, V.10
Borner, M.11
Salzberg, M.12
Ostapenko, V.13
Illiger, H.-J.14
Behringer, D.15
Bardy-Bouxin, N.16
Boni, J.17
Kong, S.18
Cincotta, M.19
Moore, L.20
more..
-
135
-
-
78650967232
-
Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer
-
Jerusalem G, Fasolo A, Dieras V, et al. Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer. Breast Cancer Res Treat. 2011;125:447-455.
-
(2011)
Breast Cancer Res. Treat.
, vol.125
, pp. 447-455
-
-
Jerusalem, G.1
Fasolo, A.2
Dieras, V.3
-
136
-
-
80051751593
-
Phase I/II study of trastuzumab in combination with everolimus RAD001 in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy
-
Morrow PK, Wulf GM, Ensor J, et al. Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy. J Clin Oncol. 2011;29:3126-3132.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 3126-3132
-
-
Morrow, P.K.1
Wulf, G.M.2
Ensor, J.3
-
137
-
-
66849136781
-
Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer
-
Baselga J, Semiglazov V, van Dam P, et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. J Clin Oncol. 2009;27:2630-2637.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 2630-2637
-
-
Baselga, J.1
Semiglazov, V.2
Van Dam, P.3
-
138
-
-
73649109111
-
Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC clinical trials group IND.163
-
Ellard SL, Clemons M, Gelmon KA, et al. Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163. J Clin Oncol. 2009;27:4536-4541.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4536-4541
-
-
Ellard, S.L.1
Clemons, M.2
Gelmon, K.A.3
-
139
-
-
73949159645
-
Does massively parallel DNA resequencing signify the end of histopathology as we know it
-
Aparicio SA, Huntsman DG. Does massively parallel DNA resequencing signify the end of histopathology as we know it? J Pathol. 2010;220:307-315.
-
(2010)
J. Pathol.
, vol.220
, pp. 307-315
-
-
Aparicio, S.A.1
Huntsman, D.G.2
|