-
1
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
10.1016/s1074-7613(00)00070-4 11114383 10.1016/S1074-7613(00)00070-4 1:CAS:528:DC%2BD3cXovV2ht7c%3D
-
B Oppmann R Lesley B Blom, et al. 2000 Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 Immunity 13 715 725 10.1016/s1074-7613(00)00070-4 11114383 10.1016/S1074-7613(00)00070-4 1:CAS:528:DC%2BD3cXovV2ht7c%3D
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
-
2
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R
-
C Parham M Chirica J Timans, et al. 2002 A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R J Immunol 168 5699 5708 12023369 1:CAS:528:DC%2BD38XktFCrtrw%3D (Pubitemid 34556153)
-
(2002)
Journal of Immunology
, vol.168
, Issue.11
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
Vaisberg, E.4
Travis, M.5
Cheung, J.6
Pflanz, S.7
Zhang, R.8
Singh, K.P.9
Vega, F.10
To, W.11
Wagner, J.12
O'Farrell, A.-M.13
McClanahan, T.14
Zurawski, S.15
Hannum, C.16
Gorman, D.17
Rennick, D.M.18
Kastelein, R.A.19
De Waal Malefyt, R.20
Moore, K.W.21
more..
-
3
-
-
0037238897
-
A unique role for IL-23 in promoting cellular immunity
-
DOI 10.1189/jlb.0602326
-
CS Lankford DM Frucht 2003 A unique role for IL-23 in promoting cellular immunity J Leukoc Biol 73 49 56 10.1189/jlb.0602326 12525561 10.1189/jlb.0602326 1:CAS:528:DC%2BD3sXnvVyitQ%3D%3D (Pubitemid 36125674)
-
(2003)
Journal of Leukocyte Biology
, vol.73
, Issue.1
, pp. 49-56
-
-
Lankford, C.S.R.1
Frucht, D.M.2
-
4
-
-
33746534417
-
IL-23 promotes tumour incidence and growth
-
DOI 10.1038/nature04808, PII NATURE04808
-
JL Langowski X Zhang L Wu, et al. 2006 IL-23 promotes tumour incidence and growth Nature. 442 461 465 10.1038/nature04808 16688182 10.1038/nature04808 1:CAS:528:DC%2BD28XnsVajtbk%3D (Pubitemid 44264796)
-
(2006)
Nature
, vol.442
, Issue.7101
, pp. 461-465
-
-
Langowski, J.L.1
Zhang, X.2
Wu, L.3
Mattson, J.D.4
Chen, T.5
Smith, K.6
Basham, B.7
McClanahan, T.8
Kastelein, R.A.9
Oft, M.10
-
5
-
-
33745968543
-
Regulatory T-cell compartmentalization and trafficking
-
DOI 10.1182/blood-2006-01-0177
-
S Wei I Kryczek W Zou 2006 Regulatory T-cell compartmentalization and trafficking Blood 108 426 431 10.1182/blood-2006-01-0177 16537800 10.1182/blood-2006-01-0177 1:CAS:528:DC%2BD28XntFehtrY%3D (Pubitemid 44061338)
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 426-431
-
-
Wei, S.1
Kryczek, I.2
Zou, W.3
-
6
-
-
8544265317
-
Forkhead-box transcription factors and their role in the immune system
-
DOI 10.1038/nri1488
-
PJ Coffer BM Burgering 2004 Forkhead-box transcription factors and their role in the immune system Nat Rev Immunol 4 889 899 10.1038/nri1488 15516968 10.1038/nri1488 1:CAS:528:DC%2BD2cXptFegtbw%3D (Pubitemid 39490764)
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.11
, pp. 889-899
-
-
Coffer, P.J.1
Burgering, B.M.T.2
-
7
-
-
8344275995
-
Crucial role of foxp3 in the development and function of human CD25∈+∈CD4∈+∈regulatory T cells
-
10.1093/intim/dxh165 15466453 10.1093/intimm/dxh165 1:CAS:528: DC%2BD2cXos1WqtbY%3D
-
H Yagi T Nomura K Nakamura, et al. 2004 Crucial role of foxp3 in the development and function of human CD25∈+∈CD4∈+∈regulatory T cells Int Immunol 16 1643 1656 10.1093/intim/dxh165 15466453 10.1093/intimm/dxh165 1:CAS:528:DC%2BD2cXos1WqtbY%3D
-
(2004)
Int Immunol
, vol.16
, pp. 1643-1656
-
-
Yagi, H.1
Nomura, T.2
Nakamura, K.3
-
8
-
-
33746599842
-
Regulatory T cells in cancer
-
DOI 10.1182/blood-2006-02-002774
-
M Beyer JL Schultze 2006 Regulatory T cells in cancer Blood 108 804 811 10.1182/blood -2006-02-002774 16861339 10.1182/blood-2006-02-002774 1:CAS:528:DC%2BD28XnvFajtrs%3D (Pubitemid 44154611)
-
(2006)
Blood
, vol.108
, Issue.3
, pp. 804-811
-
-
Beyer, M.1
Schultze, J.L.2
-
9
-
-
58549095632
-
High expression of Foxp3, IL-23p19 and surviving mRNA in colorectal carcinoma
-
10.1007/s00384-008-0588-8 18825388 10.1007/s00384-008-0588-8
-
N Stanilov L Miteva N Mintchev S Stanilova 2009 High expression of Foxp3, IL-23p19 and surviving mRNA in colorectal carcinoma Int J Colorectal Dis 24 151 157 10.1007/s00384-008-0588-8 18825388 10.1007/s00384-008-0588-8
-
(2009)
Int J Colorectal Dis
, vol.24
, pp. 151-157
-
-
Stanilov, N.1
Miteva, L.2
Mintchev, N.3
Stanilova, S.4
-
10
-
-
58249089749
-
+ T regulatory cells show strong prognostic significance in colorectal cancer
-
10.1200/jco.2008.18.7229 19064967 10.1200/JCO.2008.18.7229
-
+ T regulatory cells show strong prognostic significance in colorectal cancer J Clin Oncol 27 186 192 10.1200/jco.2008.18.7229 19064967 10.1200/JCO.2008.18.7229
-
(2009)
J Clin Oncol
, vol.27
, pp. 186-192
-
-
Salama, P.1
Phillips, M.2
Grieu, F.3
-
11
-
-
70349423483
-
+) T-cell ratio predicts a clinical outcome of human colon carcinoma
-
10.1053/j.gastro.2009.06.053 19577568 10.1053/j.gastro.2009.06.053 1:CAS:528:DC%2BD1MXht12gtr%2FP
-
+) T-cell ratio predicts a clinical outcome of human colon carcinoma Gastroenterology 137 1270 1279 10.1053/j.gastro.2009.06.053 19577568 10.1053/j.gastro.2009.06.053 1:CAS:528:DC%2BD1MXht12gtr%2FP
-
(2009)
Gastroenterology
, vol.137
, pp. 1270-1279
-
-
Sinicrope, F.A.1
Rego, R.L.2
Ansell, S.M.3
Knutson, K.L.4
Foster, N.R.5
Sargent, D.J.6
-
12
-
-
77951217044
-
+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients
-
10.1002/ijc.24989 19856313 1:CAS:528:DC%2BC3cXjvFKlsLk%3D
-
+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients Int J Cancer 126 2635 2643 10.1002/ijc.24989 19856313 1:CAS:528:DC%2BC3cXjvFKlsLk%3D
-
(2010)
Int J Cancer
, vol.126
, pp. 2635-2643
-
-
Frey, D.M.1
Droeser, R.A.2
Viehl, C.T.3
-
13
-
-
73049112438
-
Worldwide variations in colorectal cancer
-
10.3322/caac.20038 19897840 10.3322/caac.20038
-
MM Center A Jemal RA Smith E Ward 2009 Worldwide variations in colorectal cancer CA Cancer J Clin 59 366 378 10.3322/caac.20038 19897840 10.3322/caac.20038
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 366-378
-
-
Center, M.M.1
Jemal, A.2
Smith, R.A.3
Ward, E.4
-
14
-
-
73149125743
-
A novel synergistic combination of cyclophosphamide and gene transfer of interleukin-12 eradicates colorectal carcinoma in mice
-
10.1158/1078-0432.ccr-09-1861 19920110 10.1158/1078-0432.CCR-09-1861 1:CAS:528:DC%2BD1MXhsFSnu73O
-
M Malvicini M Rizzo L Alaniz, et al. 2009 A novel synergistic combination of cyclophosphamide and gene transfer of interleukin-12 eradicates colorectal carcinoma in mice Clin. Cancer Res 15 7256 7265 10.1158/1078-0432.ccr-09-1861 19920110 10.1158/1078-0432.CCR-09-1861 1:CAS:528:DC%2BD1MXhsFSnu73O
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 7256-7265
-
-
Malvicini, M.1
Rizzo, M.2
Alaniz, L.3
-
15
-
-
77951618566
-
IL-23 promotes growth and proliferation in human squamous cell carcinoma of the oral cavity
-
10.3892/ijo-00000620 20428758 10.3892/ijo-00000620 1:CAS:528: DC%2BC3cXnsVOqtLc%3D
-
M Fukuda M Ehara S Suzuki Y Ohmori H Sakashita 2010 IL-23 promotes growth and proliferation in human squamous cell carcinoma of the oral cavity Int J Oncol 36 1355 1365 10.3892/ijo-00000620 20428758 10.3892/ijo-00000620 1:CAS:528:DC%2BC3cXnsVOqtLc%3D
-
(2010)
Int J Oncol
, vol.36
, pp. 1355-1365
-
-
Fukuda, M.1
Ehara, M.2
Suzuki, S.3
Ohmori, Y.4
Sakashita, H.5
-
16
-
-
58649119388
-
Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment
-
10.1016/j.ccr.2008.12.018 19185846 10.1016/j.ccr.2008.12.018 1:CAS:528:DC%2BD1MXltFSmtLg%3D
-
M Kortylewski H Xin M Kujawski, et al. 2009 Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment Cancer Cell 15 114 123 10.1016/j.ccr.2008.12.018 19185846 10.1016/j.ccr.2008.12.018 1:CAS:528:DC%2BD1MXltFSmtLg%3D
-
(2009)
Cancer Cell
, vol.15
, pp. 114-123
-
-
Kortylewski, M.1
Xin, H.2
Kujawski, M.3
-
17
-
-
33747762947
-
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor
-
EL Jared RT Troy AS Lisa, et al. 2006 Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor J Immunol 177 3133 3142
-
(2006)
J Immunol
, vol.177
, pp. 3133-3142
-
-
Jared, E.L.1
Troy, R.T.2
Lisa, A.S.3
-
18
-
-
17044393922
-
Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells
-
10.1073/pnas. 0501675102 10.1073/pnas.0501675102
-
B Estelle D Maryam O Mohamed 2005 Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells Proc Natl Acad Sci USA 102 5138 5143 10.1073/pnas. 0501675102 10.1073/pnas.0501675102
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5138-5143
-
-
Estelle, B.1
Maryam, D.2
Mohamed, O.3
-
19
-
-
77955890952
-
Interleukin-23 drives intestinal inflammation through direct activity on T cells
-
10.1016/j.immuni. 2010.08.010 10.1016/j.immuni.2010.08.010
-
PA Philip S Chris B Sofia, et al. 2010 Interleukin-23 drives intestinal inflammation through direct activity on T cells Immunity 33 279 288 10.1016/j.immuni. 2010.08.010 10.1016/j.immuni.2010.08.010
-
(2010)
Immunity
, vol.33
, pp. 279-288
-
-
Philip, P.A.1
Chris, S.2
Sofia, B.3
-
20
-
-
77950876806
-
Foxp3 expression in p53-dependent DNA damage responses
-
10.1074/jbc.M109.047985 20075077 10.1074/jbc.M109.047985 1:CAS:528:DC%2BC3cXislyqtb0%3D
-
DJ Jung DH Jin SW Hong, et al. 2010 Foxp3 expression in p53-dependent DNA damage responses J Biol Chem 285 7995 8002 10.1074/jbc.M109.047985 20075077 10.1074/jbc.M109.047985 1:CAS:528:DC%2BC3cXislyqtb0%3D
-
(2010)
J Biol Chem
, vol.285
, pp. 7995-8002
-
-
Jung, D.J.1
Jin, D.H.2
Hong, S.W.3
-
21
-
-
34250026960
-
Monoclonal Anti-Interleukin 23 Reverses Active Colitis in a T Cell-Mediated Model in Mice
-
DOI 10.1053/j.gastro.2007.03.104, PII S0016508507006300
-
CO Elson Y Cong CT Weaver TR Schoeb McClanah an TK RB Fick RA Kastelein 2007 Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice Gastroentryology 13 2359 2370 10.1053/j.gastro.2007.03.104 10.1053/j.gastro.2007.03.104 (Pubitemid 46890867)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2359-2370
-
-
Elson, C.O.1
Cong, Y.2
Weaver, C.T.3
Schoeb, T.R.4
McClanahan, T.K.5
Fick, R.B.6
Kastelein, R.A.7
-
22
-
-
33750505009
-
Interleukin-23 drives innate and T cell-mediated intestinal inflammation
-
DOI 10.1084/jem.20061099
-
S Hue P Ahern S Buonocore, et al. 2006 Interleukin-23 drives innate and T cell-mediated intestinal inflammation J Exp Med 203 2473 2483 10.1084/jem.20061099 17030949 10.1084/jem.20061099 1:CAS:528:DC%2BD28XhtFGqtL7I (Pubitemid 44664617)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.11
, pp. 2473-2483
-
-
Hue, S.1
Ahern, P.2
Buonocore, S.3
Kullberg, M.C.4
Cua, D.J.5
McKenzie, B.S.6
Powrie, F.7
Maloy, K.J.8
-
23
-
-
33750530394
-
IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
-
DOI 10.1084/jem.20061082
-
MC Kullberg D Jankovic CG Feng, et al. 2006 IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis J Exp Med 203 2485 2494 10.1084/jem.20061082 17030948 10.1084/jem.20061082 1:CAS:528:DC%2BD28XhtFGqtL7J (Pubitemid 44664618)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.11
, pp. 2485-2494
-
-
Kullberg, M.C.1
Jankovic, D.2
Feng, C.G.3
Hue, S.4
Gorelick, P.L.5
McKenzie, B.S.6
Cua, D.J.7
Powrie, F.8
Cheever, A.W.9
Maloy, K.J.10
Sher, A.11
-
24
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
10.1172/JCI21404 16670770 10.1172/JCI21404 1:CAS:528:DC%2BD28XksVWns78%3D
-
D Yen J Cheung H Scheerens, et al. 2006 IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6 J Clin Invest 116 1310 1316 10.1172/JCI21404 16670770 10.1172/JCI21404 1:CAS:528: DC%2BD28XksVWns78%3D
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
-
25
-
-
79953246187
-
Interleukin-23-induced interleukin-23 receptor subunit expression is mediated by the Janus Kinase/signal transducer and activation of transcription pathway in human CD4 T cells
-
10.1089/jir.2010.0083 21138378
-
NF Che Mat X Zhang C Guzzo K Gee 2010 Interleukin-23-induced interleukin-23 receptor subunit expression is mediated by the Janus Kinase/signal transducer and activation of transcription pathway in human CD4 T cells J Interferon Cytokine Res 10.1089/jir.2010.0083 21138378
-
(2010)
J Interferon Cytokine Res
-
-
Che Mat, N.F.1
Zhang, X.2
Guzzo, C.3
Gee, K.4
-
26
-
-
33751546237
-
IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
-
DOI 10.1084/jem.20060244
-
JR Chan W Blumenschein E Murphy, et al. 2006 IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis J Exp Med 203 2577 2587 10.1084/jem.20060244 17074928 10.1084/jem.20060244 1:CAS:528:DC%2BD28Xht12htLbL (Pubitemid 44833335)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.12
, pp. 2577-2587
-
-
Chan, J.R.1
Blumenschein, W.2
Murphy, E.3
Diveu, C.4
Wiekowski, M.5
Abbondanzo, S.6
Lucian, L.7
Geissler, R.8
Brodie, S.9
Kimball, A.B.10
Gorman, D.M.11
Smith, K.12
Malefyt, R.D.W.13
Kastelein, R.A.14
McClanahan, T.K.15
Bowman, E.P.16
-
27
-
-
34250164929
-
Systemic administration of IL-23 induces potent antitumor immunity primarily mediated through Th1-type response in association with the endogenously expressed IL-12
-
17548592 1:CAS:528:DC%2BD2sXmtVKgtbg%3D
-
T Kaiga M Sato H Kaneda 2007 Systemic administration of IL-23 induces potent antitumor immunity primarily mediated through Th1-type response in association with the endogenously expressed IL-12 J Immunol 178 7571 7758 17548592 1:CAS:528:DC%2BD2sXmtVKgtbg%3D
-
(2007)
J Immunol
, vol.178
, pp. 7571-7758
-
-
Kaiga, T.1
Sato, M.2
Kaneda, H.3
|