메뉴 건너뛰기




Volumn 178, Issue 12, 2007, Pages 7571-7580

Systemic administration of IL-23 induces potent antitumor immunity primarily mediated through Th1-type response in association with the endogenously expressed IL-12

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIBODY; CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 23; PLASMID DNA; PROTEIN P19; PROTEIN P40;

EID: 34250164929     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.12.7571     Document Type: Article
Times cited : (81)

References (37)
  • 2
    • 0032482474 scopus 로고    scopus 로고
    • T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
    • Schoenberger, S. P., R. E. Toes, E. I. Van der Voort, R. Offringa, and C. J. Melief. 1998. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 393: 480-483.
    • (1998) Nature , vol.393 , pp. 480-483
    • Schoenberger, S.P.1    Toes, R.E.2    Van der Voort, E.I.3    Offringa, R.4    Melief, C.J.5
  • 7
    • 12044249483 scopus 로고
    • IL-12: Initiation cytokine for cell-mediated immunity
    • Scott, P. 1993. IL-12: initiation cytokine for cell-mediated immunity. Science 260: 496-497.
    • (1993) Science , vol.260 , pp. 496-497
    • Scott, P.1
  • 8
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunily
    • Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunily. Nat. Rev. Immunol. 3: 133-146.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 9
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen specific adaptive immunity. Annu. Rev. Immunol. 13: 251-276.
    • (1995) Annu. Rev. Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 12
    • 0030976279 scopus 로고    scopus 로고
    • The effect of interleukin 12 desensitization on the antitumor efficacy of recombinant interleukin 12
    • Coughlin, C. M., M. Wysocka, G. Trinchieri, and W. M. Lee. 1997. The effect of interleukin 12 desensitization on the antitumor efficacy of recombinant interleukin 12. Cancer Res. 57: 2460-2467.
    • (1997) Cancer Res , vol.57 , pp. 2460-2467
    • Coughlin, C.M.1    Wysocka, M.2    Trinchieri, G.3    Lee, W.M.4
  • 13
    • 0037238897 scopus 로고    scopus 로고
    • A unique role for IL-23 in promoting cellular immunity
    • Lankford, C. S., and D. M. Frucht. 2003. A unique role for IL-23 in promoting cellular immunity. J. Leukocyte Biol. 73: 49-56.
    • (2003) J. Leukocyte Biol , vol.73 , pp. 49-56
    • Lankford, C.S.1    Frucht, D.M.2
  • 17
    • 0036604306 scopus 로고    scopus 로고
    • A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R
    • Parham, C. M. Chirica, J. Timans, E. Vaisberg, M. Travis, J. Cheung, S. Pflanz, R. Zhang, K. P. Singh, F. Vega, et al. 2002. A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R. J. Immunol. 168: 5699-5708.
    • (2002) J. Immunol , vol.168 , pp. 5699-5708
    • Parham, C.1    Chirica, M.2    Timans, J.3    Vaisberg, E.4    Travis, M.5    Cheung, J.6    Pflanz, S.7    Zhang, R.8    Singh, K.P.9    Vega, F.10
  • 20
    • 33645318217 scopus 로고    scopus 로고
    • Diversification of T helper cell lineages: Finding the family root of IL-17-producing cells
    • Dong, C. 2006. Diversification of T helper cell lineages: finding the family root of IL-17-producing cells. Nat. Rev. Immunol. 6: 329-333.
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 329-333
    • Dong, C.1
  • 25
    • 12444328351 scopus 로고    scopus 로고
    • Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and -independent antitumor effects
    • Ugai, S., O. Shimozato, L. Yu, Y. Q. Wang, K. Kawamura, H. Yamamoto, T. Yamaguchi, H. Saisho, S. Sakiyama, and M. Tagawa. 2003. Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and -independent antitumor effects. Cancer Gene Ther. 10: 771-778.
    • (2003) Cancer Gene Ther , vol.10 , pp. 771-778
    • Ugai, S.1    Shimozato, O.2    Yu, L.3    Wang, Y.Q.4    Kawamura, K.5    Yamamoto, H.6    Yamaguchi, T.7    Saisho, H.8    Sakiyama, S.9    Tagawa, M.10
  • 29
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann, B., R. Lesley, B. Blom, J. C. Timans, Y. Xu, B. Hunte, F. Vega, N. Yu, J. Wang, K. Singh, et al. 2000. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13: 715-725.
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5    Hunte, B.6    Vega, F.7    Yu, N.8    Wang, J.9    Singh, K.10
  • 31
    • 0041672399 scopus 로고    scopus 로고
    • Dendritic cells stimulated with a bacterial product, OK-432, efficiently induce cytotoxic T lymphocytes specific to tumor rejection peptide
    • Nakahara, S., T. Tsunoda, T. Baba, S. Asabe, and H. Tahara. 2003. Dendritic cells stimulated with a bacterial product, OK-432, efficiently induce cytotoxic T lymphocytes specific to tumor rejection peptide. Cancer Res. 63: 4112-4118.
    • (2003) Cancer Res , vol.63 , pp. 4112-4118
    • Nakahara, S.1    Tsunoda, T.2    Baba, T.3    Asabe, S.4    Tahara, H.5
  • 33
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • Aggarwal, S., N. Ghilardi, M. H. Xie, F. J. de Sauvage, and A. L. Gurney. 2003. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278: 1910-1914.
    • (2003) J. Biol. Chem , vol.278 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.H.3    de Sauvage, F.J.4    Gurney, A.L.5
  • 34
    • 0029951658 scopus 로고    scopus 로고
    • Systemic administration of cellular IL-10 induces and effective, specific, and long-lived immune response against established tumors in mice
    • Berman, R. M., T. Suzuki, H. Tahara, P. D. Robbins, S. K. Narula, and M. T. Lotze. 1996. Systemic administration of cellular IL-10 induces and effective, specific, and long-lived immune response against established tumors in mice. J. Immunol. 157: 231-238.
    • (1996) J. Immunol , vol.157 , pp. 231-238
    • Berman, R.M.1    Suzuki, T.2    Tahara, H.3    Robbins, P.D.4    Narula, S.K.5    Lotze, M.T.6
  • 35
    • 0035872790 scopus 로고    scopus 로고
    • Differential effects of myeloid dendritic cells retrovirally transduced to express mammalian or viral IL-10 on CTL and NK cell functions and resistance to tumor growth
    • Takayama, T., H. Tahara, and A. W. Thomson. 2001. Differential effects of myeloid dendritic cells retrovirally transduced to express mammalian or viral IL-10 on CTL and NK cell functions and resistance to tumor growth. Transplantation 71: 1334-1340.
    • (2001) Transplantation , vol.71 , pp. 1334-1340
    • Takayama, T.1    Tahara, H.2    Thomson, A.W.3
  • 37
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells
    • Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells. Nature 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.