Biochemistry: H 2S-induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response

Science Signaling

Volumn 4, Issue 203, 2011, Pages

  Krishnan, Navasona ^a   Fu, Cexiong ^a   Pappin, Darryl J ^a   Tonks, Nicholas K ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTATHIONINE GAMMA LYASE; CYSTEINE; DITHIOTHREITOL; GLUTATHIONE; HYDROGEN SULFIDE; INITIATION FACTOR 2; PROTEIN TYROSINE PHOSPHATASE 1B; THIOREDOXIN; OXYGEN; PERK KINASE; PROTEIN KINASE R; PTPN1 PROTEIN, HUMAN; THIOL DERIVATIVE; TYROSINE;

ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; HYDRATION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; BIOLOGICAL MODEL; CELL STRAIN HEK293; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; ENDOPLASMIC RETICULUM; HELA CELL; METABOLISM; METHODOLOGY; PH; PHOSPHORYLATION; PROTEIN SYNTHESIS;

CATALYTIC DOMAIN; EIF-2 KINASE; ENDOPLASMIC RETICULUM; HEK293 CELLS; HELA CELLS; HUMANS; HYDROGEN SULFIDE; HYDROGEN-ION CONCENTRATION; MODELS, BIOLOGICAL; OXYGEN; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFHYDRYL COMPOUNDS; TYROSINE;

EID: 83655165310     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2002329     Document Type: Article

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