Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2α RNA-dependent protein kinase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 1, 2006, Pages 63-68

  Su, Qiaozhu ^a   Wang, Shuo ^a   Baltzis, Dionissios ^a   Qu, Li Ke ^a   Wong, Andrew Hoi Tao ^a,b   Koromilas, Antonis E ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Cell proliferation; Protein phosphorylation; Translational control; Virus infection

Indexed keywords

DOUBLE STRANDED RNA; GLUTATHIONE TRANSFERASE; INITIATION FACTOR 2ALPHA; PROTEIN KINASE; RNA DEPENDENT PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RABBIT; RAT; RNA BINDING; RNA TRANSLATION; VESICULAR STOMATITIS VIRUS; VIRUS CARCINOGENESIS; VIRUS INFECTION;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; EIF-2 KINASE; ENZYME ACTIVATION; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; MICE, KNOCKOUT; MUTATION; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; TYROSINE;

ANIMALIA; EUKARYOTA; ORYCTOLAGUS CUNICULUS; VESICULAR STOMATITIS VIRUS;

EID: 30444452652     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0508207103     Document Type: Article

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