Dysfunctional telomeres in human BRCA2 mutated breast tumors and cell lines

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 729, Issue 1-2, 2012, Pages 90-99

  Bodvarsdottir, Sigridur K ^a   Steinarsdottir, Margret ^b   Bjarnason, Hordur ^a   Eyfjord, Jorunn E ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

^b LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

Author keywords

BRCA2; Breast carcinoma; Extrachromosomal telomeric repeat DNA; Interstitial telomeric sequences; Telomere dysfunction induced foci; Telomere sister chromatid exchanges

Indexed keywords

DNA; GAMMA HISTONE H2AX; HISTONE H2AX; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOGENESIS; BREAST EPITHELIUM; BREAST TUMOR; CELL DIVISION; CHROMATID; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; CHROMOSOME END TO END FUSION; CONTROLLED STUDY; DNA CONTENT; DNA DAMAGE; DNA REPLICATION; EPITHELIUM CELL; EXTRACHROMOSOMAL TELOMERIC REPEAT; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERPHASE; INTERSTITIAL TELOMERE SEQUENCE; METAPHASE CHROMOSOME; MUTATION RATE; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE; TARGETED GENE REPAIR; TELOMERE; TELOMERE CAPPING; TELOMERE DYSFUNCTION INDUCED FOCI; TELOMERE HOMEOSTASIS; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

ALLELES; BRCA2 PROTEIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CHROMOSOME ABERRATIONS; FEMALE; GENE FREQUENCY; HETEROZYGOTE; HISTONES; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; SISTER CHROMATID EXCHANGE; TELOMERE;

EID: 83555168326     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2011.10.002     Document Type: Article

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