Measurement of telomeric DNA content in human tissues

BioTechniques

Volumn 23, Issue 3, 1997, Pages 476-484

  Bryant, Jennifer E ^a   Hutchings, Kent G ^a   Moyzis, Robert K ^b   Griffith, Jeffrey K ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA FRAGMENT; NUCLEOPROTEIN;

ARTICLE; ASSAY; CONTROLLED STUDY; DNA CONTENT; DNA STRAND BREAKAGE; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MEASUREMENT; PLACENTA; SOUTHERN BLOTTING; TELOMERE;

EUKARYOTA;

EID: 0030961037     PISSN: 07366205     EISSN: None     Source Type: Journal    
DOI: 10.2144/97233st05     Document Type: Article

References (18)

1. Adamson, D.J.A., D.J. King and N.E. Haites. 1992. Significant telomere shortening in childhood leukemia. Can. J. Genet. Cytol. 61:204-206.
2. Allsopp, R.C., E. Chang, M. Kashefiaazam, E.I. Rogaev, M.A. Piatyszek, J.W. Shay and C.B. Harley. 1995. Telomere shortening is associated with cell division in vitro and in vivo. Exp. Cell Res. 220:194-200.
3. Brown, W.R., P.J. MavKinnon, A. Villasante, N. Spurr, V. Buckle and M. Dobson. 1990. Structure and polymorphism of human telomere-associated DNA. Cell 63:119-132.
4. Counter, C.M., A.A. Avillon, C.E. LeFeuvre, N.G. Stewart, C.W. Greider, C.B. Harley and S. Bacchetti. 1992. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11:1921-1929.
5. de Lange, T., L. Shiue, R.M. Myers, D.R. Cox, S.L. Naylor, A.M. Killery and H.E. Varmus. 1990. Structure and variability of human chromosome ends. Mol. Cell Biol. 10:518-527.
6. Hastie, N.D., M. Dempster, M.G. Dunlop, E.M. Thompson, D.K. Green and R.C. Allshire. 1990. Telomere reduction in human colorectal carcinoma and with aging. Nature 346:866-868.
7. Hiyama, E., L. Gollahon, T. Kataoka, K. Kuroi, T. Yokoyama, A. Gazdar, K. Hiyama, A. Mieczyslaw, A. Piatyszek and J. Shay. 1996. Telomerase acitivity in human breast cancer. J. Natl. Cancer Inst. 88:116-122.
8. Hiyama, K., S. Ishioka, Y. Shirotani, K. Inai, E. Hiyama, I. Murakami, T. Isobe, T. Inamizu and M. Yamakido. 1995. Alterations in telomeric repeat length in lung cancer are associated with loss of heterozygosity in p53 and Rb. Oncogene 10:937-944.
9. Meyne, J., L.G. Littlefield and R.K. Moyzis. 1989. Labeling of human centromeres using an alphoid DNA concensus sequence: application to the scoring of chromosome aberrations. Mutat. Res. 226:75-79.
10. n, present at the telomeres of human chromosomes. Proc. Natl. Acad. Sci. USA 85:6622-6626.
11. Odagiri, E., N. Kanda, K. Jibiki, R. Demura, E. Aikawa and H. Demura. 1993. Reduction of telomeric length and c-erb2 gene amplification in human breast cancer, fibro-adenoma and gynecomastia. Cancer 73:2978-2984.
12. Schmitt, H., N. Blin, H. Zankl and H. Scherthan. 1994. Telomere length variation in normal and malignant human tissues. Genes Chromosom. Cancer 11:171-177.
13. Shay, J.W., H. Werbin and W.E. Wright. 1996. Telomeres and telomerase in human leukemias. Leukemia 10:1255-1261.
14. Takauchi, K., S. Tashiro, M. Ohtaki and N. Kamada. 1994. Telomere reduction of specific chromosome translocation in acute myelocytic leukemia. Japn. J. Cancer Res. 85-127-130.
15. Weber, B., L. Allen, R.E. Magnis, P.J. Goodfellow, L. Smith and M.R. Hayden. 1991. Intrachromosomal location of the telomere repeat (TTAGGG)n. Mamm. Genome 1:211-216.
16. Wells, R.A., G.G. Germino, S.K. Krishna, V.J. Buccle and S.T. Reeders. 1990. Telomere-related sequences in interstitial sites in the human genome. Genomics 5:699-704.
17. Zhuang, Z., P. Bertheau, M. Emmert-Buck, L. Liotta, J. Gnarra, M. Linehan and I. Lubensky. 1995. A microdissection technique for archival DNA analysis of specific cell populations in lesions .1 mm in size. Am. J. Pathol. 146:620-625.
18. Zhuang, Z., M. Merino, R. Chuaqui, L. Liotta and M. Emmert-Buck. 1995. Identical allelic loss on chromosome 11q13 in microdissected in situ invasive human breast cancer. Cancer Res. 55:467-471.