Telomere sister chromatid exchange and the process of aging

Aging

Volumn 2, Issue 10, 2010, Pages 727-730

  Blagoev, Krastan B ^a   Goodwin, Edwin H ^b   Bailey, Susan M ^c  

^a NATIONAL SCIENCE FOUNDATION   (United States)

^b KromaTiD Inc   (United States)

^c Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Aging; BLM; T SCE; WRN

Indexed keywords

ANTIOXIDANT; BLOOM SYNDROME HELICASE; EXODEOXYRIBONUCLEASE; RECQ HELICASE; WRN PROTEIN, HUMAN;

AGING; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BLOOM SYNDROME; CELL AGING; CELL PROLIFERATION; COMPUTER SIMULATION; CUTANEOUS PARAMETERS; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; NEOPLASM; PHYSIOLOGY; RADIATION EXPOSURE; SISTER CHROMATID EXCHANGE; TELOMERE; WERNER SYNDROME;

AGING; ANIMALS; ANTIOXIDANTS; BLOOM SYNDROME; CELL AGING; CELL PROLIFERATION; COMPUTER SIMULATION; EXODEOXYRIBONUCLEASES; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; RECQ HELICASES; SISTER CHROMATID EXCHANGE; SKIN AGING; TELOMERE; WERNER SYNDROME;

EID: 79954480154     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100206     Document Type: Article

References (22)

1. Goodwin E, Meyne J. Strand-specific FISH reveals orientation of chromosome 18 alphoid DNA. Cytogenet Cell Genet 1993; 63:126-127.
2. Bailey SM, Goodwin EH, Cornforth MN. Strand-specific fluorescence in situ hybridization: the CO-FISH family. Cytogenet Genome Res 2004; 107:14-17.
3. Meyne J, Goodwin EH. Direction of Dna-Sequences Within Chromatids Determined Using Strand-Specific Fish. Chromosome Research 1995; 3:375-378.
4. Bailey SM, Brenneman MA, Goodwin EH. Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells. Nucleic Acids Res 2004; 32:3743-3751.
5. Cesare AJ, Reddel RR. Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet 2010.
6. Blagoev KB, Goodwin EH. Telomere exchange and asymmetric segregation of chromosomes can account for the unlimited proliferative potential of ALT cell populations. DNA Repair (Amst) 2008; 7:199-204.
7. Salk D, Bryant E, Hoehn H, Johnston P, Martin GM. Growth characteristics of Werner syndrome cells in vitro. Adv Exp Med Biol 1985; 190:305-311.
8. Hagelstrom RT, Blagoev KB, Niedernhofer LJ, Goodwin EH, Bailey SM. Hyper telomere recombination accelerates replicative senescence and may promote premature aging. Proc Natl Acad Sci U S A 2010; 107:15768-15773.
9. Antal T, Blagoev KB, Trugman SA, Redner S. Aging and immortality in a cell proliferation model. J Theor Biol 2007; 248:411-417.
10. Liu L, Bailey SM, Okuka M, Munoz P, Li C, Zhou L, Wu C, Czerwiec E, Sandler L, Seyfang A, Blasco MA, Keefe DL. Telomere lengthening early in development. Nat Cell Biol 2007; 9:1436- 1441.
11. Zalzman M, Falco G, Sharova LV, Nishiyama A, Thomas M, Lee SL, Stagg CA, Hoang HG, Yang HT, Indig FE, Wersto RP, Ko MS. Zscan4 regulates telomere elongation and genomic stability in ES cells. Nature 2010; 464:858-863.
12. Wang Y, Erdmann N, Giannone RJ, Wu J, Gomez M, Liu Y. An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres. Proc Natl Acad Sci U S A 2005; 102:10256-10260.
13. Coppe JP, Desprez PY, Krtolica A, Campisi J. The senescenceassociated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol 2010; 5:99-118.
14. Hagelstrom RT, Blagoev KB, Niedernhofer LJ, Goodwin EH, Bailey SM. Hyper telomere recombination accelerates replicative senescence and may promote premature aging. Proc Natl Acad Sci U S A 2010; 107:15768-15773.
15. Wu L, Multani AS, He H, Cosme-Blanco W, Deng Y, Deng JM, Bachilo O, Pathak S, Tahara H, Bailey SM, Deng Y, Behringer RR, Chang S. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell 2006; 126:49-62.
16. Rai R, Zheng H, He H, Luo Y, Multani A, Carpenter PB, Chang S. The function of classical and alternative non-homologous endjoining pathways in the fusion of dysfunctional telomeres. EMBO J 2010; 29:2598-2610.
17. Rhee DB, Wang Y, Mizesko M, Zhou F, Haneline L, Liu Y. FANCC suppresses short telomere-initiated telomere sister chromatid exchange. Hum Mol Genet 2010; 19:879-887.
18. Yaar M, Eller MS, Gilchrest BA. Fifty years of skin aging. J Investig Dermatol Symp Proc 2002; 7:51-58.
19. Kosmadaki MG, Gilchrest BA. The role of telomeres in skin aging/photoaging. Micron 2004; 35:155-159.
20. Sugimoto M, Yamashita R, Ueda M. Telomere length of the skin in association with chronological aging and photoaging. J Dermatol Sci 2006; 43:43-47.
21. Latt SA, Schreck RR. Sister chromatid exchange analysis. Am J Hum Genet 1980; 32:297-313.
22. Bailey SM, Meyne J, Chen DJ, Kurimasa A, Li GC, Lehnert BE, Goodwin EH. DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes. Proceedings of the National Academy of Sciences of the United States of America 1999; 96:14899-14904.