Plants used as antidiabetics in popular medicine in Rio Grande do Sul, southern Brazil

Journal of Ethnopharmacology

Volumn 139, Issue 1, 2012, Pages 155-163

  Trojan Rodrigues, M ^a   Alves, T L S ^a   Soares, G L G ^a   Ritter, M R ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Diabetes mellitus; Ethnobotany; Folk medicine; South Brazil

Indexed keywords

ACHYROCLINE SATUREIOIDES EXTRACT; ANTIDIABETIC AGENT; AVERRHOA CARAMBOLA EXTRACT; BACCHARIS ARTICULATA EXTRACT; BACCHARIS TRIMERA EXTRACT; BAUHINIA FORFICATA EXTRACT; BIDENS PILOSA EXTRACT; CYNARA SCOLYMUS EXTRACT; LEANDRA AUSTRALIS EXTRACT; MANGIFERA INDICA EXTRACT; PHYLLANTHUS NIRURI EXTRACT; PLANT EXTRACT; SACCHARUM OFFICINARUM EXTRACT; SALVIA OFFICINALIS EXTRACT; SPHAGNETICOLA TRILOBATA EXTRACT; SYZYGIUM CUMINI EXTRACT; UNCLASSIFIED DRUG;

ASTERACEAE; BRAZIL; DIABETES MELLITUS; ETHNOBOTANY; HUMAN; KNOWLEDGE BASE; LEGUME; MEDICINAL PLANT; MELASTOMATACEAE; MYRTACEAE; NONHUMAN; REVIEW;

ASTERACEAE; BACCHARIS TRIMERA; BAUHINIA FORFICATA; BIDENS PILOSA; CYNARA SCOLYMUS; FABACEAE; LEANDRA; MELASTOMATACEAE; MYRTACEAE; SPHAGNETICOLA TRILOBATA; SYZYGIUM CUMINI;

EID: 83555166263     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.10.034     Document Type: Article

References (90)

1. A.C. Adebajo, E.O. Olawode, O.R. Omobuwajo, S.A. Adesanya, F. Begrow, A. Elkhawad, M.A. Akanmu, R. Edrada, P. Proksch, T.J. Schimidt, M. Klaes, and E.J. Verspohl Hypoglycaemic constituents of Stachytarpheta cayennensis leaf Planta Medica 73 2007 241 250 (Pubitemid 46917476)
2. A.O. Aderibigbe, T.S. Emudianughe, and B.A.S. Lawal Evaluation of the antidiabetic action of Mangifera indica in mice Phytotherapy Research 15 2001 456 458 (Pubitemid 32762401)
3. F.J. Alarcon-Aguilar, R. Roman-Ramos, J.L. Flores-Saenz, and F. Aguirre-Garcia Investigation on the hypoglycaemic effects of extracts of four Mexican medicinal plants in normal and alloxan-diabetic mice Phytotherapy Research 16 2002 383 386 (Pubitemid 34700279)
4. American Diabetes Association Standards of medical care in diabetes Diabetes Care 30 2007 4 41
5. R. Anandharajan, S. Jaiganesh, N.P. Shankernarayanan, R.A. Viswakarma, and A. Balakrishnan In vitro glucose uptake activity of Aegles marmelos and Syzygium cumini by activation of Glut-4 PI3 kinase and PPARgamma in L6 myotubes Phytomedicine 13 6 2006 434 441 (Pubitemid 43728733)
6. J.F. Barbosa Estudo etnobotânico das plantas de uso medicinal e místico utilizadas na comunidade quilombola de Nova Real, Bom Retiro do Sul, estado do Rio Grande do Sul. Monografia de Conclusão de Curso 2005 Universidade do Vale do Rio dos Sinos São Leopoldo
7. J.M. Barbosa-Filho, T.H.C. Vasconcelos, A.A. Alencar, L.M. Batista, R.A.G. Oliveira, D.N. Guedes, H.S. Falcão, M.D. Moura, M.F.F.M. Diniz, and J. Modesto-Filho Plants and their active constituents from South, Central, and North America with hypoglycemic activity Brazilian Journal of Pharmacognosy 15 2005 392 413
8. F.M.C. Barros, K.N. Pereira, G.D. Zanetti, and B.M. Heinzmann Plantas de uso medicinal no município de São Luiz Gonzaga, RS, Brasil Latin American Journal of Pharmacy 26 2007 652 662
9. A. Bopp, K.S. De Bona, L.P. Bellé, R.N. Moresco, and M.B. Moretto Syzygium cumini inhibits adenosine deaminase activity and reduces glucose levels in hyperglycemic patients Fundamental & Clinical Pharmacology 23 2009 501 507
10. K.N. Borges, H.P. Bautista, and S. Guilhera Diabetes - utilizaão de plantas medicinais como forma opcional de tratamento Revista Eletrônica da Faculdade de Farmácia 5 2008 12 20
11. L.F.V. Bresciani, R.A. Yunes, C. Burger, L.E. De Oliveira, K.L. Bóf, and V. Cechinel-Filho Seasonal variation of kaurenoic acid, a hypoglycemic diterpene present in Wedelia paludosa (Acmela brasiliensis) (Asteraceae) Journal of Biosciences 59 2004 229 232 (Pubitemid 38492618)
12. J.R. Carney, J.M. Krenisky, R.T. Williamson, and J. Luo Achyrofuran, a new antihyperglycemic dibenzofuran from the South American medicinal plant Achyrocline satureioides Journal of Natural Products 65 2002 203 205 (Pubitemid 34171183)
13. L.H. Cazarolli, L. Zanatta, E.H. Alberton, M.S.R.B. Figueiredo, P. Folador, R.G. Damazio, M.G. Pizzolatti, and F.R.M.B. Silva Flavonoids: cellular and molecular mechanism of action in glucose homeostasis. Mini-reviews Medicinal Chemistry 8 2008 1032 1038
14. L.H. Cazarolli, P. Folador, H.H. Moresco, I.M.C. Brighente, M.G. Pizzolatt, and F.R. Mena Barreto Silva Mechanism of action of the stimulatory effect of apigenin-6-C-(2-O-alpha-l-rhamnopyranosyl) beta-l-fucopyranoside on C-14-glucose uptake Chemico-Biological Interactions 179 2009 407 412
15. L.H. Cazarolli, P. Folador, M.G. Pizzolatti, and F.R. Mena Barreto Silva Signaling pathways of kaempferol-3-neohesperidoside in glycogen synthesis in rat soleus muscle Biochimie 91 2009 843 849
16. V. Cechinel Chemical composition and biological potential of plants from the genus Bauhinia Phytotherapy Research 23 2009 1347 1354
17. Ceolin T.; 2009. Conhecimento sobre plantas medicinais entre agricultores de base ecológica da Região Sul do Rio Grande do Sul. M.Sc. Thesis. Pelotas.
18. C.L.T. Chang, H.K. Kuo, S.L. Chang, Y.M. Chiang, T.H. Lee, W.M. Wu, L.F. Shyur, and W.C. Yang The distinct effects of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice Journal of Biomedical Science 12 2005 79 89
19. S.L. Chang, C.L.T. Chang, Y.M. Chiang, R.H. Hsieh, C.R. Tzeng, T.K. Wu, H.K. Sytwu, L.F. Shyur, and W.C. Yang Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice Planta Medica 70 2004 1045 1051
20. C.F. Chau, C.H. Chen, and C.Y. Lin Insoluble fiber-rich fractions derived from Averrhoa carambola: hypoglycemic effects determined by in vitro methods Food Science and Technology 37 2004 331 335
21. R.M.T. Dahlgren A revised system of classification of the angiosperms Botany Journal of the Linnean Society 80 1980 91 124
22. S.Q. De Oliveira, F. Dal-Pizzol, G. Gosmann, D. Guillaume, J.C. Moreira, and E.P. Schenkel Antioxidant activity of Baccharis articulata extracts: isolation of a new compound with antioxidant activity Free Radical Research 37 2003 555 559 (Pubitemid 36410897)
23. L.C. Di Stasi Plantas Medicinais - verdades e mentiras 1st ed. 2007 Fundaão Editora Unesp São Paulo
24. M. Eidi, A. Eidi, and H. Zamanizadeh Effect of Salvia officinalis L. leaves on serum glucose and insulin in healthy and streptozotocin-induced diabetic rats Journal of Ethnopharmacology 100 2005 310 313 (Pubitemid 41206627)
25. E. Elisabetsky, and G.P. Coelho de Souza Etnofarmacologia como ferramenta na busca de substâncias ativas C.M.O. Simões, E.P. Schenkel, G. Gosmann, J.P.P. Mello, L.A. Mentz, P.R. Petrovick, Farmacognosia: da planta ao medicamento 6th ed. 2007 Editora da Universidade/UFRGS/UFSC Porto Alegre/Florianópolis 107 122
26. M. Farswan, P.M. Mazumder, V. Parcha, and A. Upaganlawar Modulatory Effect of Syzygium cumini seeds and its isolated compound on biochemical parameters in diabetic rats Pharmacognosy Magazine 5 18 2009 127 133
27. E.B. Ferreira, L.C. Fernandes, S.B. Galende, D.A.G. Cortez, and R.B. Bazotte Hypoglycemic effect of the hydroalcoholic extract of leaves of Averrhoa carambola L. (Oxalidaceae) Brazilian Journal of Pharmacognosy 18 2008 339 343
28. L. Figueroa-Valverde, F. Diaz-Cedillo, A. Camacho-Luis, and M.L. Ramos Induced effects by Ruta graveolens L.; Rutaceae, Cnidoscolus chayamansa McVaugh, Euphorbiaceae, and Citrus aurantium L.; Rutaceae, on glucose, cholesterol and triacylglycerides levels in a diabetic rat model Brazilian Journal of Pharmacognosy 19 2009 898 907
29. J. Friedman, Z. Yaniv, A. Dafni, and D. Palewitch A preliminary classification of the healing potential of medicinal plants, based on a rational analysis of an ethnopharmacological field survey among bedouins in the Negev Desert, Israel Journal of Ethnopharmacology 16 1986 275 287
30. T.S. Fröde, and Y.S. Medeiros Animal models to test drugs with potential antidiabetic activity Journal of Ethnopharmacology 115 2008 173 183 (Pubitemid 50011561)
31. Garlet, T.M.B.; 2000. Levantamento das plantas medicinais utilizadas no município de Cruz Alta, RS, Brasil. M.Sc. Thesis. Universidade Federal do Rio Grande do Sul, Porto Alegre.
32. T.M.B. Garlet, and B. Irgang Plantas medicinais utilizadas na medicina popular por mulheres trabalhadoras rurais de Cruz Alta, Rio Grande do Sul, Brasil Revista Brasileira de Plantas Medicinais 4 2001 9 18 (Pubitemid 34093259)
33. A.M. Giulietti, R.M. Harley, L.P. Queiroz, M.G.L. Wanderley, and C. Van Den Berg Biodiversity and conservation of plants in Brazil Conservation Biology 19 2005 632 663
34. C.M.P. Gourgue, M.M. Champ, Y. Lozano, and J. Delort-Laval Dietary fiber from mango byproducts - characterization and hypoglycemic effects determined by in vitro methods Journal of Agricultural and Food Chemistry 40 1992 1864 1868
35. A.P.S. Hass Categorizaão tóxico-terapêutica da plantas medicinais usadas no município de Maquine - Rio Grande do Sul 2003 Monografia de Conclusão de Curso. Universidade Federal do Rio Grande do Sul Porto Alegre
36. Y.J. Hsu, T.H. Lee, C.L.T. Chang, Y.T. Huang, and W.C. Yang Anti-hyperglycemic effects and mechanism of Bidens pilosa water extract Journal of Ethnopharmacology 122 2009 379 383
37. International Diabetes Federation, 2011. Unite for diabetes. Bruxelas. Available from: http://www.worlddiabetesday.org/the-campaign/unite-for-diabetes (accessed 13.03.11).
38. ISI Web of Knowledge, 2010. Thomson Reuters. Available from: http://www.isiwebofknowledge.com (accessed 13.03.01).
39. A.P. Jorge, H. Horst, E. De Sousa, M.G. Pizzolatti, and F.R.M.B. Silva Insulinomimetic effects of kaempferitrin on glycaemia and on 14 C-glucose uptake in rat soleus muscle Chemico-Biological Interactions 149 2004 89 96 (Pubitemid 39387212)
40. M. Jung, M. Park, H.C. Lee, Y.H. Kang, E.S. Kang, and S.K. Kim Antidiabetic agents from medicinal plants Current Medicinal Chemistry 13 2006 1203 1218
41. N.M. Khalil, M.T. Pepato, and I.L. Brunetti Free radical scavenging profile and myeloperoxidase inhibition of extracts from antidiabetic plants: Bauhinia forficata and Cissus sicyoides Biological Research 41 2008 165 171
42. M.I. Kotowaroo, M.F. Mahomoodally, A. Gurib-Fakim, and A.H. Subratty Screening of traditional antidiabetic medicinal plants of mautitius for possible α-amylase inhibitory effects in vitro Phytotherapy Research 20 2006 228 231
43. Kubo, R.; 1997. Levantamento das plantas de uso medicinal em Coronel Bicaco, RS. M.Sc. Thesis. Universidade Federal do Rio Grande do Sul, Porto Alegre.
44. K. Kubitzki, and O.R. Gottlieb Phytochemical aspects of angiosperm origin and evolution Acta Botanica Neerlandica 33 387 1984 457 468
45. K. Kubitzki, and O.R. Gottlieb Micromolecular patterns and the evolution and major classification of Angiosperms Taxon 33 1984 375 391
46. A. Kumar, R. Ilavarasan, T. Jayachandran, M. Decaraman, P. Aravindan, N. Padmanabhan, and M.V. Krishnan Anti-diabetic activity of Syzygium cumini and its isolated compound against streptozotocin-induced diabetic rats Journal of Medicinal Plants Research 2 2008 246 249
47. Z.C.S. Leitzke Levantamento das plantas medicinais da comunidade Nossa Senhora da Conceião - Canguu-RS 2003 Trabalho de Conclusão do curso de Ciências Biológicas - Universidade Federal de Pelotas Pelotas, RS
48. C.F. Lima, M.F. Azevedo, R. Araujo, M. Fernandes-Ferreira, and C. Pereira-Wilson Metformin-like effect of Salvia officinalis (common sage): is it useful in diabetes prevention? British Journal of Nutrition 96 2006 326 333 (Pubitemid 46470100)
49. T.R. Löwe Estudo etnobotânico em uma área rural do município de Três de Maio, RS 2004 Trabalho de Conclusão do Curso de Ciências Biológicas, Instituto de Biologia, Universidade Federal de Pelotas, RS
50. Magalhães, R.G.; 1997. Plantas medicinais na região do Alto Uruguai-RS: conhecimentos de João Martins Fiúza, "Sarampião". M.Sc. Thesis. Universidade Federal do Rio Grande do Sul, Porto Alegre.
51. N. Malviya, S. Jain, and S. Malviya Antidiabetic potential of medicinal plants Acta Poloniae Pharmaceutica 67 2010 113 118
52. R. Marles, and N. Farnsworth Antidiabetic plants and their active constituents Phytomedicine 2 1995 137 165
53. Marodin, S.M.; 2000. Plantas utilizadas como medicinais no município de Dom Pedro de Alcântara, Rio Grande do Sul. M.Sc. Thesis. Universidade Federal do Rio Grande do Sul, Porto Alegre.
54. E.M. Martha O uso das plantas medicinais pela comunidade da associaão dos agricultores construtores da Palma - assentamento 24 de Novembro 2003 Trabalho de Conclusão do Curso de Ciências Biológicas, Instituto de Biologia, Universidade Federal de Pelotas, RS
55. L.G.S. Martins, L. Senna-Valle, and N.A. Pereira Princípios ativos e atividades farmacológicas de 8 plantas popularmente conhecidas por nome de medicamentos comerciais Revista Brasileira de Plantas Medicinais 7 2 2005 73 76 (Pubitemid 40895823)
56. G. Negri Diabetes melito: plantas e princípios ativos naturais hipoglicemiantes Brazilian Journal of Pharmaceutical Sciences 41 2005 121 141
57. C.O. Okoli, A.F. Ibiam, A.C. Ezike, P.A. Akah, and T.C. Okoye Evaluation of antidiabetic potentials of Phyllanthus niruri in alloxan diabetic rats African Journal of Biotechnology 9 2010 248 259
58. A.C.P. Oliveira, D.C. Endringer, L.A.S. Amorim, L. Das Graas, M. Brandão, and M.M. Coelho Effect of the extracts and fractions of Baccharis trimera and Syzygium cumini on glycaemia of diabetic and non-diabetic mice Journal of Ethnopharmacology 102 2005 465 469 (Pubitemid 41571856)
59. J.D. Phillipson Phytochemistry and pharmacology Phytochemistry 68 2007 2960 2972
60. E.P.P. Pinto, M.C.M. Amorozo, and A. Furlan Conhecimento popular sobre plantas medicinais em comunidades rurais de mata atlântica - Itacaré, BA, Brasil Acta Botanica Brasilica 20 2006 751 762 (Pubitemid 46513531)
61. Possamai, R.M.; 2000. Levantamento etnobotânico das plantas de uso medicinal em Mariana Pimentel, Rio Grande do Sul. M.Sc. Thesis. Universidade Federal do Rio Grande do Sul, Porto Alegre.
62. M.R.M. Rafiullah, A.W. Siddiqui, S.R. Mir, M. Ali, K.K. Pillai, and S. Singh Antidiabetic activity of some Indian medicinal plants Pharmaceutical Biology 44 2006 95 99
63. B. Ramesh, and K.V. Pugalendi Influence of umbelliferone on glycoprotein components in diabetic rats Toxicology Mechanisms and Methods 17 2007 153 159 (Pubitemid 46631436)
64. B. Ramesh, and K.V. Pugalendi Influence of umbelliferone on membrane-bound ATPases in streptozotocin-induced diabetic rats Pharmacological Reports 59 2007 339 348 (Pubitemid 47299735)
65. M.R. Ritter, G.R. Sobierajski, E.P. Schenkel, and L.A. Mentz Plantas usadas como medicinais no município de Ipê, RS, Brasil Revista Brasileira de Farmacognosia 12 2002 51 62
66. G. Roglic Global prevalence of diabetes: estimates for the year 2000 and projections for 2030 Diabetes Care 27 2004 10147 11053
67. G. Roglic, N. Unwin, P.H. Bennett, C. Mathers, J. Tuomilehto, S. Nag, V. Connolly, and H. King The burden of mortality attributable to diabetes - realistic estimates for the year 2000 Diabetes Care 28 2005 2130 2135 (Pubitemid 41242456)
68. T. Schoenfelder, C.Z. Warmlin, M.S. Manfredini, L.L. Pavei, J.V. Réus, T.C. Tristão, M.S. Fernandes, and L. Costa-Campos Hypoglycemic and hypolipidemic effect of leaves from Syzygium cumini (L.) Skeels, Myrtaceae in diabetic rats Brazilian Journal of Pharmacognosy 20 2010 222 227
69. Sebold, D.F.; 2003. Levantamento etnobotânico de plantas de uso medicinal no município de Campo Bom, Rio Grande do Sul, Brasil. M.Sc. Thesis. Universidade Federal do Rio Grande do Sul, Porto Alegre.
70. C.M.O. Simões, L.A. Mentz, E.L. Schenkel, B.E. Irgang, and J.R. Stehmann Plantas da medicina popular no Rio Grande do Sul 5th ed. 1986 Editora da UFRGS Porto Alegre
71. N. Singh, and M. Gupta Effects of ethanolic extract of Syzygium cumini (L.) Skeels seed powder on pancreatic islets of alloxan diabetic rats Indian Journal of Experimental Biology 45 2007 861 867
72. E.L.C. Soares, G.S. Vendruscolo, S.M. Eisinger, and R.A. Záchia Estudo etnobotânico do uso dos recursos vegetais em São João do Polêsine, RS, Brasil, no período de outubro 1999 a junho de 2001. I - Origem e fluxo do conhecimento Revista Brasileira de Plantas Medicinais 6 2004 69 95 (Pubitemid 39388150)
73. C.R.F. Souza, S.R. Georgetti, M.J. Salvador, M.J.V. Fonseca, and W.P. Oliveira Antioxidant activity and physical-chemical properties of spray and spouted bed dried extracts of Bauhinia forficata Brazilian Journal of Pharmaceutical Sciences 46 2009 209 218
74. Stevens, P.F.; 2011. Angiosperm Phylogeny Website. Version 9, June 2008 [and more or less continuously updated since]. Available from: http://www.mobot.org/MOBOT/research/APweb/ (accessed in 10 abr. 2011).
75. M. Takahashi, C. Konno, and H. Hikino Antidiabetes drugs 10. Isolation and hypoglycemic activity of saccharans A, B, C, D, E and F glycans of Saccharum officinarum stalks Planta Medica 51 1985 258 260 (Pubitemid 15000791)
76. C.C. Teixeira, C.A. Rava, P.M. Silva, R. Melchior, R. Argenta, F. Anselmi, C.R.C. Almeida, and F.D. Fuchs Absence of antihyperglycemis effect of jambolan in experimental and clinical models Journal of Ethnopharmacology 71 2000 343 347 (Pubitemid 30440689)
77. C.C. Teixeira, and F.D. Fuchs The efficacy of herbal medicines in clinical models: the case of jambolan Journal of Ethnopharmacology 108 2006 16 19 (Pubitemid 44498997)
78. C.C. Teixeira, F.D. Fuchs, L.S. Weinert, and J. Esteves The efficacy of folk medicines in the management of type 2 diabetes mellitus: results of a randomized controlled trial of Syzygium cumini (L.) Skeels Journal of Clinical Pharmacy and Therapeutics 31 2006 1 5
79. C.C. Teixeira, L.P. Pinto, F.H.P. Kessler, L. Knijnik, C.P. Pinto, G.J. Gastaldo, and F.D. Fuchs The effect of Syzygium cumini (L.) Skeels on post-prandial blood glucose levels in non-diabetic rats and rats with streptozotocin-induced diabetes mellitus Journal of Ethnopharmacology 56 1997 209 213 (Pubitemid 27271815)
80. C.C. Teixeira, L.S. Weinert, D.C. Barbosa, C. Ricken, J.F. Esteves, and F.D. Fucks Syzygium cumini (L.) Skeels in the treatment of type 2 diabetes - results of a randomized, double-blind, double-dummy, controlled trial Diabetes Care 27 2004 3019 3020 (Pubitemid 39565084)
81. The Plant List, 2011. Version 1. Available from: http://www.theplantlist. org (accessed 18.03.11).
82. Tropicos, 2011. Missouri Botanical Garden (Mobot). Available from: http://www.tropicos.org (accessed 10 abr. 2011).
83. R.P. Ubillas, C.D. Mendez, S.D. Jolad, J. Luo, S.R. King, T.J. Carlson, and D.M. Fort Antihyperglycemic acetylenic glucosides from Bidens pilosa Planta Medica 66 2000 82 83 (Pubitemid 30097291)
84. G.S. Vendruscolo, and L.A. Mentz Levantamento etnobotânico das plantas utilizadas como medicinais por moradores do bairro Ponta Grossa, Porto Alegre, Rio Grande do Sul, Brasil, Iheringia Série Botânica 61 2006 83 103
85. Vendruscolo, G.S.; 2004. Estudo etnobotânico das plantas utilizadas como medicinais por moradores do bairro Ponta Grossa, Porto Alegre, Rio Grande do Sul. M.Sc. Thesis. Universidade Federal do Rio Grande do Sul, Porto Alegre.
86. I.M. Villaseñor, and M.R.A. Lamadrid Comparative anti-hyperglycemic potentials of medicinal plants Journal of Ethnopharmacology 104 2006 129 131 (Pubitemid 43234093)
87. G.P. Volpato, D.C. Damasceno, I.M.P. Calderon, and M.V.C. Rudge Revisão de plantas brasileiras com comprovado efeito hipoglicemiante no controle do diabetes mellitus Revista Brasileira de Plantas Medicinais 4 2002 35 45 (Pubitemid 34670119)
88. G.P. Volpato, D.C. Damasceno, M.V.C. Rudge, C.R. Padovani, and I.M. Calderon Effect of Bauhinia forficata aqueous extract on the maternal-fetal outcome and oxidative stress biomarkers of streptozotocin-induced diabetic rats Journal of Ethnopharmacology 116 2008 131 137
89. G.L. Von Poser Polissacarídeos C.M.O. Simões, E.P. Schenkel, G. Gosmann, J.P.P. Mello, L.A. Mentz, P.R. Petrovick, Farmacognosia: da planta ao medicamento 6th ed. 2007 Editora da Universidade/UFRGS/UFSC Porto Alegre/Florianópolis 497 517
90. L.A. Witters The blooming of the French lilac Journal of Clinical Investigation 108 2001 1105 1107 (Pubitemid 32995367)