Modulatory effect of Syzygium cumini seeds and its isolated compound on biochemical parameters in diabetic rats

Pharmacognosy Magazine

Volumn 4, Issue 18, 2009, Pages 127-133

  Farswan, Mamta ^a   Mazumder, Papiya Mitra ^b   Parcha, V ^a   Upaganlawar, Aman ^c  

^a Sardar Bhagwan Singh Post Gratudate Institute of Biomedical Sciences & Research   (India)

^b BIRLA INSTITUTE OF TECHNOLOGY   (India)

^c M S UNIVERSITY OF BARODA   (India)

Author keywords

sitosterol; Atherogenic index; Diabetes; Hepatic enzymes; Lipid peroxidation; Streptozotocin; Syzygium cumini

Indexed keywords

ACETONE; ALANINE AMINOTRANSFERASE; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; CHLOROFORM; CHOLESTEROL; CUMINOSIDE; GLIBENCLAMIDE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LACTATE DEHYDROGENASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METHANOL; PETROLEUM ETHER; SUGAR; SYZYGIUM CUMINI EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; WATER; GLUCOSE; LIVER ENZYME; LOW DENSITY LIPOPROTEIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; CHEMICAL ANALYSIS; CHOLESTEROL BLOOD LEVEL; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DIET RESTRICTION; DRUG ACTIVITY; DRUG EFFECT; DRUG ISOLATION; FEMALE; GLUCOSE BLOOD LEVEL; HEART PROTECTION; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; NONHUMAN; PLANT SEED; RAT; STREPTOZOCIN DIABETES; TRIACYLGLYCEROL BLOOD LEVEL; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; LIPID ANALYSIS; LIPOPROTEIN BLOOD LEVEL; MEDICINAL PLANT; NON INSULIN DEPENDENT DIABETES MELLITUS; SYZYGIUM CUMINI; TRADITIONAL MEDICINE;

EID: 74049129383     PISSN: 09731296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. S. Rajasekaran, K. Ravi, K. Sivagnanam and S. Subramanian. Beneficial effect of Aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes. Journal of clinical and experimental pharmacology and physiology. 33: 232-237 (2006).
2. T. Jenson, S. Stender and T. Deckert. Abnormalities in plasma concentrations of lipoprotein and fibrinogen in type 1 diabetes mellitus with increased urinary albumin excretion. Diabetolgia. 31: 142-59 (1988).
3. K. Srinivasan, B. Viswanad, L. Asrat, C.L. Kaul and Ramarao. Combination of high fat diet fed and low dose streptozotocin treated rats: A model for type II diabetes and pharmacological screening. J. Pharmacol. Research. 52: 313- 320 (2005).
4. A. R. Saltiel and J. M. Olefsky. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes. 45: 1661-1669 (1996)
5. M. A. Banerji and H. E. Lebovitz. Treatment of insulin resistance in diabetes mellitus. Eurr. J. pharmacol. 490: 135-46 (2004).
6. D Kritchevsky. Dietary protein, cholesterol and atherosclerosis: A review of the early history. J.Nutr. 125: S589-93 (1995).
7. F. M. Al-Awaidi, M. A. Khattar and K. A. Gumaa. ON the mechanism of the hypoglycemic effect of a plant extract. Diabetologia. 28: 432-434 (1985).
8. M. Rakesh, V. Wazir and R. Kapil. Biotheraupatic diterpene glucoside from Tinospora cordifolia. J. Indian. Chem. Sco: 361 (1995).
9. P. Pushparay, C.H. Tan and B. K. H. Tan. Effect of Averrhoea bilimbi leaf extract on blood glucose and lipid in STZ- diabetic rats. J. ethanopharmacol. 72: 69-76. (2000).
10. K.R. Kirtikar and B. D. Basu. In Indian Medicinal Plants.Vol. II, (Periodical Experts, New Delhi, 1975) 1052-53.
11. H. D. Brahmachari, and K.T. Augusti. Hypoglycemic agents from Indian indigenous plants. Journal of Pharmacy and Pharmacology. XIII (1):143 (1961).
12. Ajit Kar, B. K. Choudhary and N.G. Bandyopadhyay. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxon diabetic rats. Journal of ethnopharmacology. 84: 105-108 (2003).
13. M.T. Pepato, D.M. Mori, A.M. Baviera. J.B. Harami, R. C. Vendramini and L.L Brunetti. Fruit of the jambolan tree (Eugenia jambolana Lam.) and experimental diabetes. Journal of Ethanopharmacol. 96: 43-48 (2005).
14. A. Sofowora. Medicinal plants and traditional medicines in Africa, (John Wiley and Sons, Chichester; 1993) 256-57.
15. M.E. Wall, C.R. Eddy, M.L. McClenna and M.E. Klump. Detection and estimation of steroids and saponins in plant tissues. Anal. Chem. 24: 1337-1342 (1952).
16. M.N. Ghosh. Toxicity studies, In Fundamentals of experimental pharmacology, (Hilton and Company, Kolkata, 2005) 190-197
17. B. Portha, M. Kerogoat, O. Blondel and D. Bailbe. The rat models of NIDDM by neonatal streptozotocin. Diabet. Met. 15: 61- 75 (1989).
18. S.R. Sharma, S.K. Dweidi and D. Swarup. Hypoglycemic, antihyperglycemic and hypolipidemic activities of Caesalpinia bonducella seeds in rats. J. Ethanopharmacol. 39-44 (1997).
19. A. C. parekh and D. H. Jung. Cholesterol determination with ferric acetate uranyl acetate and sulfuric acid-ferrous sulfate reagent. Anal.Chem. 42: 1423-7 (1970).
20. E.W. Rice. Triglyceride in serum. In: ROedrik P, McDonal RP (eds). Standard methods in Clinical Chemistry. Academic Press, New York; 215-22 (1970).
21. M. Burstein and H.R. Scholnick. Precipitation of chylomicrones and very low density proteins from human serum and sodium lauryl sulphate. Life Sci. 11:177-84 (1972).
22. J. King. The transferase alanine and transaminase. In: Van D (Ed.). Practical Clinical Enzymology, Nostrand, London; 363-75 (1965).
23. S. Reitman and S. Frankel, Am. J. Clin. Path. 28: 56 (1957).
24. S Seifter and S. England. Energy metabolism. In: AriasI Popper H, Schacter D et al. (ed.). The Liver: Biology and Pathophysiology. Rauen Press, New York; 219-49 (1982).
25. L. Al-shamaony, S.M. Al-Khajraji and H.A.A. Twij. Hypoglycemic effect of Artemisia herba Alba. II. Effect of a valuable extract on some blood parameters in diabetic animals. J. Ethanopharmacol. 43:167-71 (1994).
26. N Sekar, S. Williams, N. Balasubramaniyam, P. kamarajan and S. Govindasamy. Optimization of sodium orthovanadate to treat streptozotocin - induced diabetes in rats. J. Biosci. 15: 67-75 (1990).